scholarly journals Is Bioavailable Vitamin D Better Than Total Vitamin D to Evaluate Vitamin D Status in Obese Children?

2021 ◽  
Vol 13 (4) ◽  
pp. 391-399
Author(s):  
Gülin Karacan Küçükali ◽  
Özlem Gülbahar ◽  
Şervan Özalkak ◽  
Hasan Dağlı ◽  
Serdar Ceylaner ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Status ◽  
Obese Children ◽  
Total Vitamin ◽  
Bioavailable Vitamin D ◽  
Better Than

scholarly journals Is Bioavailable Vitamin D Better Than Total Vitamin D to Evaluate Vitamin D Status in Obese Children?

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Gülin Karacan Küçükali ◽  
Özlem Gülbahar ◽  
Şervan Özalkak ◽  
Hasan Dağlı ◽  
Serdar Ceylaner ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Status ◽  
Obese Children ◽  
Total Vitamin ◽  
Bioavailable Vitamin D ◽  
Better Than

scholarly journals Modulating effect of vitamin D status on serum anti-adenovirus 36 antibody amount in obese children: National Food and Nutrition Surveillance

2019 ◽  
Author(s):  
Bahareh Nikooyeh ◽  
Bruce Hollis ◽  
Tirang Reza Neyestani
Keyword(s):  
Vitamin D ◽  
Viral Infections ◽  
Normal Weight ◽  
Surveillance Program ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Obese Children ◽  
Food And Nutrition ◽  
Unit Increase ◽  
Adenovirus 36

Abstract Background. Among the causative factors of obesity, a rather newly proposed theory is viral infections. The association of ADV-36 infection and obesity has been reported by some research groups in children. We hypothesized that the association between ADV-36 infection and adiposity may be mediated by sub-optimal vitamin D status of the host. To examine this hypothesis, we conducted a case control study on children and adolescents with normal weight, over weight and obesity. Methods. In total, 91 (normal weight: 33, overweight: 33, obese: 25) apparently healthy children aged 5-18 years were randomly selected from the registered population at National Food and Nutrition Surveillance Program (NFNS). The groups were matched based on age and sex. Anthropometric, biochemical and serological assessments were performed. Results. The amount of anti-ADV36-Ab increased whereas circulating concentrations of calcidiol decreased across BMI categories with higher amounts in normal weight than in overweight and obese children (31.0±16.4, 22.5±10.5 and 21.9±9.8 nmol/L, respectively, p=0.004). Logistic regression analysis revealed that for each unit increment of anti-ADV36-Ab, the chance of increase in weight was 8.5 times (OR: 8.5, p=0.029). Interestingly, when 25(OH)D was introduced into the model, anti-ADV36-Ab was no longer the predictor of weight increment and the chance of increase in weight reduced 5% for each unit increase in calcidiol concentration (OR: 0.95, p=0.012). Conclusion. It is suggested that ADV36-induced lipogenesis and weight gain may be mediated by vitamin D deficiency in obese children. Further studies are warranted.

scholarly journals Inadequate vitamin D status is associated with lower food plus supplemental intake of vitamin D in children of South Asian ethnicity living in the National Capital Region of Canada

2021 ◽  
Author(s):  
Stephen Brooks ◽  
W.M. Nimal Ratnayake ◽  
Isabelle Rondeau ◽  
Eleonora Swist ◽  
Kurtis Sarafin ◽  
...  
Keyword(s):  
Vitamin D ◽  
South Asian ◽  
Vitamin D Status ◽  
National Capital Region ◽  
Total Vitamin ◽  
Serum 25Ohd ◽  
Vitamin D Intake ◽  
Asian Children ◽  
National Capital ◽  
Lower Vitamin

Vitamin D status, measured in a Vitamin D Standardization Program certified laboratory, was assessed among children of South Asian and European ethnicity living in the national capital region of Canada to explore factors that may account for inadequate status. Demographic information, dietary and supplemental vitamin D over 30 d prior to measurement of serum 25-hydroxyvitamin D (25OHD), and anthropometry were measured (age 6.0-18.9 y; n=58/group; Feb-Mar 2015). No group related differences in age, height and BMI Z-scores or in food vitamin D intakes were observed. Standardized serum 25OHD was lower in South Asian children (mean ± SD: 39.0 ± 16.8 nmol/L vs European: 58.4 ± 15.8 nmol/L). A greater proportion of South Asian children had serum 25OHD < 40 nmol/L (56.9 vs 8.6%, P < 0.0001) and fewer took supplements (31 vs 50%, P = 0.0389). In a multi-factorial model (r2 = 0.54), lower vitamin D status was associated with overweight/obese BMI and older age (14-18 y); no interaction with ethnicity was observed. Lower vitamin D status was associated with lower total vitamin D intake only in South Asian children. This study reinforces the importance of public health actions towards meeting vitamin D intake recommendations among those of high-risk deficiency. Novelty: • A higher proportion of South Asian vs. European children had inadequate vitamin D status. • Lower vitamin D status was associated with a BMI in the overweight/obese range. • Lower vitamin D status was associated with lower total vitamin D intake in South Asian but not European children.

scholarly journals Bioavailable vitamin D is more tightly linked to mineral metabolism than total vitamin D in incident hemodialysis patients

2012 ◽  
Vol 82 (1) ◽  
pp. 84-89 ◽  
Author(s):  
Ishir Bhan ◽  
Camille E. Powe ◽  
Anders H. Berg ◽  
Elizabeth Ankers ◽  
Julia B. Wenger ◽  
...  
Keyword(s):  
Vitamin D ◽  
Mineral Metabolism ◽  
Hemodialysis Patients ◽  
Total Vitamin ◽  
Bioavailable Vitamin D

A Rapid Chemiluminescence Immunoassay for Total Vitamin D Status Assessment in Fingertip Blood

2020 ◽  
Vol 66 (08/2020) ◽  
Author(s):  
Xiang Chen ◽  
Shanshan Sun ◽  
Qian Liu ◽  
Feng Ren ◽  
Zhonghu Bai ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Status ◽  
Total Vitamin ◽  
Chemiluminescence Immunoassay ◽  
Status Assessment

scholarly journals Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status

2021 ◽  
Vol 14 ◽  
pp. 117863882110187
Author(s):  
Hedyeh Saneifard ◽  
Marjan Shakiba ◽  
Ali Sheikhy ◽  
Leila Baniadam ◽  
Fatemeh Abdollah Gorji ◽  
...  
Keyword(s):  
Vitamin D ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Tanner Stage ◽  
Additional Risk Factor ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Obese Children ◽  
Increased Risk ◽  
Vitamin D Levels

Background: Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity. Objective: The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level. Method: A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020. Results: 220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, P < .001). Mean vitamin D level was lower in obese children compared with non-obese ( P < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) ( P = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) ( P = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls ( P < .001). Conclusion: Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups.

scholarly journals total and free vitamin D in type 2 diabetes mellitus patients in Baghdad city

2021 ◽  
Vol 2 (02) ◽  
pp. 79-93
Author(s):  
Zainab Subber ◽  
Ghassan Al-Shamma ◽  
Hashim Hashim
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Fasting Glucose ◽  
Free Form ◽  
Vitamin D Status ◽  
Total Vitamin ◽  
Free Vitamin D

Background: The free-form of vitamin D has been used by many researchers as an index of vitamin D status in health and disease. Several methods are there to estimate free, total, and even bioavailable vitamin D. Objective: The present work was carried out to measure free vitamin D using a special formula suggested by Bikle and Schwartz in 2019, which includes the vitamin D binding protein (VDBP). The results will be used to evaluate the vitamin D status in patients with type 2 diabetes mellitus (T2DM), and its relation to the disease progression. Methods: Sixty-four patients with T2DM and 73 healthy subjects, all from Baghdad city, were enrolled in the current study from March to October 2020. For each participant, fasting blood glucose, hemoglobin (HbA1c), insulin resistance HOMA-IR, and body mass index (BMI) were measured in addition to the total vitamin D and VDBP. Moreover, free vitamin D was calculated by the formula of Bikle &amp; Schwartz. Results: There were highly significant correlations between total vitamin D and absolute values of free vitamin D or its percentage. The difference in total vitamin D was significant between patients and healthy controls with no significant change in VDBP, free and bio-available vitamin D, while free vitamin D% was higher in the patient’s group. Correlations between vitamin D and each of BMI, fasting glucose, HbA1c, and HOMA-IR were not significant; however, there was a negative correlation with BMI and fasting glucose in the healthy control subjects only. The Receiver Operating Characteristic (ROC) curve analysis of vitamin D in the diagnosis of diabetes mellitus was poor. Conclusion: Total vitamin D can represent vitamin D status, but it cannot be used as a factor for diagnosing T2DM. However, it could be of importance to change the glycemic status.

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