A Prospective Examination of the Relationship between Physical Activity and Dementia Risk in Later Life

2012 ◽  
Vol 26 (6) ◽  
pp. 333-340 ◽  
Author(s):  
Mary Elizabeth Bowen

Purpose. To examine the relationship between vigorous physical activity and dementia risk. Design. Prospective study design utilizing physical activity data from the Health and Retirement Study and cognitive outcome data from the Aging, Demographics, and Memory Study. Setting. Community-based. Subjects. Adults age 71 and over (N = 808) with 3 to 7 years of physical activity information prior to dementia/no dementia diagnosis. Measures. Physical activity was measured by participation in vigorous activities such as aerobics, sports, running, bicycling, and heavy housework three or more times per week (yes/no). Dementia diagnosis was based on an expert panel (e.g., neuropsychologists, neurologists, geropsychiatrists) who performed and reviewed a battery of neuropsychological tests. Analysis. Binary logistic regression models were used to account for demographic characteristics, genetic risk factors (one or two apolipoprotein E ε4 alleles), health behaviors (e.g., smoking, drinking alcohol), health indicators (body mass index), and health conditions (e.g., diabetes, heart disease) in a sequential model-building process. Results. The relationship between vigorous physical activity and dementia risk remained robust across models. In the final model, older adults who were physically active were 21% (p ≤ .05) less likely than their counterparts to be diagnosed with dementia. Conclusion. Vigorous physical activity may reduce the risk for dementia independently of the factors examined here. This study's findings are important given that few preventative strategies for dementia have been explored beyond hormonal therapy and anti-inflammatory drugs.

Author(s):  
Thaynã Alves Bezerra ◽  
Paulo Felipe Ribeiro Bandeira ◽  
Anastácio Neco de Souza Filho ◽  
Cain Craig Truman Clark ◽  
Jorge Augusto Pinto Silva Mota ◽  
...  

Background: The relationship between moderate to vigorous physical activity (MVPA) and fundamental motor skill (FMS) is inconsistent in early childhood, due to its complex and nonlinear characteristics. This study aimed to analyze the nonlinear relationships between MVPA, FMS, body mass index (BMI), sex, and age in preschoolers. Methods: This cross-sectional study with preschoolers (n = 204; 4.0 [0.8] y old; 99 boys), provided objective physical activity data, FMS assessments, and BMI. The associations between MVPA, FMS, BMI, sex, and age were explored using the network analysis (RStudio and qgraph). Results: Boys were more motor competent than girls in all FMS skills, while girls were more active than boys during the weekend. Older children were less active than their younger peers during these days. MVPA is weak and differently related to each FMS, and the leap skill emerged with the highest betweenness and strength values in the network. Conclusions: For the assessed preschoolers, when considering BMI, age, and sex, the relationships between MVPA and FMS are inconsistent, and leap emerged as the main variable. During early childhood, these variables are connected as part of a complex system in which each skill has a dynamic role within the emerging pattern.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Jennifer Barnes ◽  
Samantha Concha ◽  
Erin Fejes ◽  
Jonathan Grimwood ◽  
Karen Dennis ◽  
...  

Abstract Objectives Dietary compensation for energy expenditure is one hypothesis for why many individuals struggle to maintain a healthy body weight. The objective of this investigation was to assess the relationship between the amount of moderate to vigorous physical activity (MVPA) and dietary intake of college students within corresponding 24-hour periods. Methods College students enrolled in a personal health and fitness class were recruited to participate in this study. As part of the course, all students completed a 7 day food journal and were concurrently assigned to wear a Polar Active fitness tracker with a tracker wear time of 24 hours per day. Physical activity data was collected from consenting participants and served as the independent variable. Dietary intake including but not limited to total kilocalories (kcals), carbohydrate (CHO), protein, fat, and selected micronutrients were also collected. Pearson correlations were assessed using SPSS between physical activity and dietary variables. Further, amount of daily MVPA was divided into <30 minutes, 30–60 minutes, and > 60 minutes per recorded day. ANOVA was utilized to compare dietary means of various activity levels. Results A total of 110 students participated in this study with 50% female, 45% male, 5% that did not answer, mean age of 21.3 (±1.7) and BMI 24.7 (±3.7). A weak but positive correlation was identified between total minutes of MVPA and total kcal intake (r = 0.124, P = 0.007). The total intake of fat (g) (r = 0.16, P < 0.001), saturated fat (g) (r = 0.11, P = 0.01), CHO (g) (r = 0.17, P < 0.001), protein (g) (r = 0.10, P = 0.03), and added sugar (r = 0.09, P = 0.04) increased with greater time spent in MVPA. No relationship was detected for fiber intake. When participants were separated into physical activity categories, those in the lowest category consumed more trans-fat than both the middle and high category (P = 0.003). Conclusions College students in this study tended to increase their overall intake as physical activity increased. The lack of relationship between physical activity and fiber intake in combination with the positive relationship detected with added sugar suggests that the quality of carbohydrate may decrease as students perform more physical activity. Funding Sources None to report.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 342-342
Author(s):  
Jason Newsom ◽  
Emily Denning ◽  
Ana Quinones ◽  
Miriam Elman ◽  
Anda Botoseneanu ◽  
...  

Abstract Racial/ethnic disparities in multimorbidity (≥2 chronic conditions) and their rate of accumulation over time have been established. Studies report differences in physical activity across racial/ethnic groups. We investigated whether racial/ethnic differences in accumulation of multimorbidity over a 10-year period (2004-2014) were mediated by physical activity using data from the Health and Retirement Study (N = 10,724, mean age = 63.5 years). Structural equation modeling was used to estimate a latent growth curve model of changes in the number of self-reported chronic conditions (of nine) and investigate whether the relationship of race/ethnicity (non-Hispanic Black, Hispanic, non-Hispanic White) to change in the number of chronic conditions was mediated by physical activity after controlling for age, sex, education, marital status, personal wealth, and insurance coverage. Results indicated that Blacks engaged in significantly lower levels of physical activity than Whites (b = -.171, □ = -.153, p &lt; .001), but there were no differences between Hispanics and Whites (b = -.010, □ = -.008, ns). Physical activity also significantly predicted both lower initial levels of multimorbidity (b = -1.437, □ = -.420, p &lt; .001) and greater decline in multimorbidity (b = -.039, □ = -.075, p &lt; .001). The indirect (mediational) effect for the Black vs. White comparison was significant (b = .007, □ = .011, 95% CI [.004,.010]). These results provide important new information for understanding how modifiable lifestyle factors may help explain disparities in multimorbidity in middle and later life, suggesting greater need to reduce sedentary behavior and increase activity.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Lydia Q. Ong ◽  
John Bellettiere ◽  
Citlali Alvarado ◽  
Paul Chavez ◽  
Vincent Berardi

Abstract Background Prior research examining the relationship between cannabis use, sedentary behavior, and physical activity has generated conflicting findings, potentially due to biases in the self-reported measures used to assess physical activity. This study aimed to more precisely explore the relationship between cannabis use and sedentary behavior/physical activity using objective measures. Methods Data were obtained from the 2005–2006 National Health and Nutrition Examination Survey. A total of 2,092 participants (ages 20–59; 48.8% female) had accelerometer-measured sedentary behavior, light physical activity, and moderate-to-vigorous physical activity. Participants were classified as light, moderate, frequent, or non-current cannabis users depending on how often they used cannabis in the previous 30 days. Multivariable linear regression estimated minutes in sedentary behavior/physical activity by cannabis use status. Logistic regression modeled self-reported moderate-to-vigorous physical activity in relation to current cannabis use. Results Fully adjusted regression models indicated that current cannabis users’ accelerometer-measured sedentary behavior did not significantly differ from non-current users. Frequent cannabis users engaged in more physical activity than non-current users. Light cannabis users had greater odds of self-reporting physical activity compared to non-current users. Conclusions This study is the first to evaluate the relationship between cannabis use and accelerometer-measured sedentary behavior and physical activity. Such objective measures should be used in other cohorts to replicate our findings that cannabis use is associated with greater physical activity and not associated with sedentary behavior in order to fully assess the potential public health impact of increases in cannabis use.


Author(s):  
Annie M. Constable ◽  
Josie E. Porter ◽  
Danielle Benger ◽  
Dimitris Vlachopoulos ◽  
Alan R. Barker ◽  
...  

Purpose: Moderate-to-vigorous physical activity (MVPA) positively influences bone mineral content (BMC) in prepubertal children, but it is unknown whether this relationship is partially mediated by free leptin index. The aim of this study was to examine whether the relationship between MVPA and total body less head (TBLH) BMC is mediated or moderated by free leptin index in prepubertal children. Methods: We performed a cross-sectional analysis on 401 children (194 girls) from baseline examinations of the Physical Activity and Nutrition in Childhood Study. We applied the four-way decomposition mediation analysis method to assess whether free leptin index, measured from fasted blood samples, mediated the relationship between accelerometer-measured MVPA and TBLH BMC measured by dual-energy X-ray absorptiometry. Results: MVPA had a positive controlled direct effect on TBLH BMC in girls and boys (β = 0.010 to 0.011, p < 0.05). There was no mediation or interaction between MVPA, free leptin index and TBLH BMC in girls or boys (β = −0.000 to 0.001, p > 0.05). Conclusion: Our study indicates that MVPA positively influences TBLH BMC through pathways not related to free leptin index in predominantly normal-weight prepubertal children, likely primarily through mechanical loading. The relationships between MVPA, free leptin index and TBLH BMC may be influenced by other factors such as pubertal status and adiposity, so it is unknown whether these observations extend to overweight and obese children at different stages of puberty.


2010 ◽  
Vol 22 (3) ◽  
pp. 369-378 ◽  
Author(s):  
Joey C. Eisenman ◽  
Mark A. Sarzynski ◽  
Jerod Tucker ◽  
Kate A. Heelan

The purpose of this study was to examine if offspring physical activity may affect the relationship between maternal overweight and offspring fatness and blood pressure (BP). Subjects included 144 maternal-child pairs (n = 74 boys and 70 girls, mean age = 7.3 yrs). Maternal prepregnancy BMI was determined by self-report. Offspring characteristics included resting systolic and diastolic BP, body fatness by dual energy x-ray absorbtiometry, and moderate-to-vigorous physical activity (MVPA) using the Actigraph accelerometer. Children whose mothers were overweight or obese prepregnancy (Prepreg OW) were significantly larger and fatter than children from mothers with a normal prepregnancy BMI (Prepreg NORM). Prepreg OW children also had higher mean arterial pressure than Prepreg NORM children. BP values were not different across maternal Prepreg BMI/MVPA groups. Percent fat was significantly different across Prepreg BMI/MVPA groups. Prepreg OW children that did not meet the daily recommended value of MVPA were the fattest. Prepreg OW children that attained 360 min of MVPA/day had a mean percent body fat that was similar to Prepreg NORM children of either MVPA group.


2014 ◽  
Vol 26 (3) ◽  
pp. 221-230 ◽  
Author(s):  
Katrina D. DuBose ◽  
Andrew J. McKune

The relationship between physical activity levels, salivary cortisol, and the metabolic syndrome (MetSyn) score was examined. Twenty-three girls (8.4 ± 0.9 years) had a fasting blood draw, waist circumference and blood pressure measured, and wore an ActiGraph accelerometer for 5 days. Saliva samples were collected to measure cortisol levels. Previously established cut points estimated the minutes spent in moderate, vigorous, and moderate-to-vigorous physical activity. A continuous MetSyn score was created from blood pressure, waist circumference, high-density-lipoprotein (HDL), triglyceride, and glucose values. Correlation analyses examined associations between physical activity, cortisol, the MetSyn score, and its related components. Regression analysis examined the relationship between cortisol, the MetSyn score, and its related components adjusting for physical activity, percent body fat, and sexual maturity. Vigorous physical activity was positively related with 30 min post waking cortisol values. The MetSyn score was not related with cortisol values after controlling for confounders. In contrast, HDL was negatively related with 30 min post waking cortisol. Triglyceride was positively related with 30 min post waking cortisol and area under the curve. The MetSyn score and many of its components were not related to cortisol salivary levels even after adjusting for physical activity, body fat percentage, and sexual maturity.


2018 ◽  
Vol 16 (7) ◽  
Author(s):  
Oliver Ling Hoon Leh ◽  
Nur Hidayah Shaharom ◽  
Marlyana Azyyati Marzukhi ◽  
Sharifah Zannierah Syed Marzuki

The natural ecosystems are increasingly being replaced by urban built-up area due to fast urbanisation. The urban development pressure brought urban areas to the uncontrolled built environment which, in turn, significantly compromises the quality of public spaces and facilities. Furthermore, the urban environment discourages active living. Thus, research on the relationship between urbanisation and physical health is rapidly coming to the force. Urbanisation can have detrimental effects, particularly on physical health, which further attributed to unsustainable urban development. A study was carried out at Sri Pahang Public Housing (Flat), Kuala Lumpur with the aim to investigate the healthy lifestyle among residents and the relationship with the public facilities available at study area for the physical activity. Data was obtained through questionnaire survey. The relationship between healthy lifestyle particularly the level of physical activity and the facilities in the study area was analysed using correlation test. It was found that most of the respondents were physically inactive and their healthy lifestyle can be related to the planning aspects of facilities in the study area.


2020 ◽  
pp. 1-12
Author(s):  
Brad R. Julius ◽  
Amy M.J. O’Shea ◽  
Shelby L. Francis ◽  
Kathleen F. Janz ◽  
Helena Laroche

Purpose: The authors examined the relationship between mother and child activity. Methods: The authors compared moderate–vigorous physical activity (MVPA) and sedentary time of low-income mothers with obesity and their 6- to 12-year-old children on week (WD) and weekend (WE) days. A total of 196 mother–child pairs wore accelerometers simultaneously for a week. Mothers completed questionnaires. Spearman correlation and multivariate regression were used. Results: WE MVPA (accelerometry) was significantly correlated between mothers with children aged 6–7 (rs = .35) and daughters (rs = .27). Self-reported maternal PA time spent with one of their children was significantly correlated with the WE MVPA of all children (rs = .21) and children aged 8–10 (rs = .22) and with the WD MVPA of all children (rs = .15), children aged 8–10 (rs = .23), aged 11–12 (rs = .52), and daughters (rs = .37), and inversely correlated to the WD sedentary time of all children (rs = −.21), children aged 8–10 (rs = −.30), aged 11–12 (rs = −.34), daughters (rs = −.26), and sons (rs = −.22). In multivariate regression, significant associations were identified between reported child–mother PA time together and child MVPA and sedentary time (accelerometry). Conclusions: Mothers may influence the PA levels of their children with the strongest associations found in children aged 6–7 and daughters. Mother–child coparticipation in PA may lead to increased child MVPA and decreased sedentary behavior.


Sign in / Sign up

Export Citation Format

Share Document