scholarly journals Evaluation of wound healing and antibacterial properties of methanolic root extract of Stephania dinklagei (Engl.) Diels

2015 ◽  
Vol 12 (6) ◽  
pp. 122
Author(s):  
Sunday Ositadimma Udegbunam ◽  
Nnabuike Prince Igbokwe ◽  
Rita Ijeoma Udegbunam ◽  
Theophilus Okafor Nnaji ◽  
Madubuike Umunna Anyanwu
Keyword(s):  
Wound Healing ◽  
Antibacterial Properties ◽  
Root Extract

scholarly journals Phytochemical Screening, Antioxidant and Antibacterial Activities of the Root Extract of Cyphostemma adenocaule (Steud. ex A. Rich.) Wild & R.B.Drumm

2021 ◽  
Vol 10 (2) ◽  
pp. 105-110
Author(s):  
Abdulbasit Haliru Yakubu ◽  
Mohammed Mustapha Mohammed ◽  
Abdulqadir Bukar Bababe ◽  
Hassan Yesufu Braimah
Keyword(s):  
Scientific Evidence ◽  
Antibacterial Properties ◽  
Plant Secondary Metabolites ◽  
Biological Properties ◽  
Chloroform Extract ◽  
Chemical Diversity ◽  
Root Extract ◽  
Moderate Activity ◽  
Phytochemical Screening ◽  
Test Organisms

Plant secondary metabolites have provided important bioactive principles for developing new lead compounds. Within their confinement, they exhibit unique chemical diversity, which influences their diverse biological properties. The Vitaceae family is known for its potent antioxidant and antibacterial phytoconstituents, among other biological properties. Cyphostemma adenocaule is one of the family members explored for its ethnomedicinal properties. This study undertook the evaluation of the phytochemical, antioxidant, and antibacterial properties of the root extract of Cyphostemma adenocaule. Preliminary phytochemical screening revealed the presence of flavonoids, alkaloids, carbohydrates & glycoside, saponins, and tannins. The methanol root extract had the highest activity in the DPPH assay, providing IC50 (50% inhibition) of 10.87µg/ml, followed by n-Hexane (IC50 74.10µg/ml) and chloroform (IC50 74.31µg/ml) extract. In the antibacterial assay, the chloroform extract was active against E. coli (24.00±0.15) and had moderate activity against Staph. aureus (12.5±0.18). The n-Hexane extract was completely inactive against the test organisms while the methanol extract showed poor activity against the test organisms. The present study adds to the existing literature on Cyphostemma adenocaule with scientific evidence into its biological properties.

Preparation and in vitro osteogenic, angiogenic and antibacterial properties of cuprorivaite (CaCuSi4O10, Cup) bioceramics

RSC Advances ◽  
2016 ◽  
Vol 6 (51) ◽  
pp. 45840-45849 ◽  
Author(s):  
Tian Tian ◽  
Chengtie Wu ◽  
Jiang Chang
Keyword(s):  
Wound Healing ◽  
Sol Gel ◽  
Antibacterial Properties ◽  
Antibacterial Activities ◽  
Gel Method ◽  
Sol Gel Method

Cuprorivaite firstly synthesized by sol–gel method with angiogenic and antibacterial activities for wound healing application.

scholarly journals Effect of Carica papaya Extract toward Incised Wound Healing Process in Mice (Mus musculus) Clinically and Histologically

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Rachmi Fanani Hakim ◽  
Fakhrurrazi ◽  
Dinni
Keyword(s):  
Wound Healing ◽  
Mus Musculus ◽  
Carica Papaya ◽  
Healing Process ◽  
Antibacterial Properties ◽  
The Body ◽  
Wound Healing Process ◽  
Protective Function ◽  
Incised Wound ◽  
Anterior Teeth

Wound healing entails a sequence of complex biological processes, which is a protective function of the body that focuses on a quick recovery. Reducing wound healing time is crucial in a wound as it lowers the chance of infection and decreases complications and costs. Papaya extract was obtained by a maceration method. It contains papain enzyme, flavonoid, saponin, and alkaloid, which act as an anti-inflammatory, astringent substance, vasodilator, antioxidant, analgesic, with antifungal, and antibacterial properties, and increase the collagen synthesis. This study aimed to assess the effect of Carica papaya extract application toward incised wound healing process in mice (Mus musculus) clinically and histologically. This experimental laboratory study was performed using 24 mice weighing between 30 and 40 grams and 12 and 14 weeks of age as experimental animals. Each group was incised along 5 mm at the labial gingiva under both of mandible anterior teeth with a depth reaching alveolar bone. Papaya extract was applied topically in the morning and evening for 14 days. The clinical result was obtained by assessing the length of wound closure measured every day for 14 days. Based on the statistic test result, it showed that the papaya extract has a significant effect (p≤0.05) toward the healing process of an incised oral wound in mice. Histologically at day 14, 75% concentration papaya extract showed perfect epithelial layer and fibrillation.

scholarly journals Correction: Ga and Ce ion-doped phosphate glass fibres with antibacterial properties and their composite for wound healing applications

2019 ◽  
Vol 7 (45) ◽  
pp. 7246-7246
Author(s):  
Agata Łapa ◽  
Mark Cresswell ◽  
Ian Campbell ◽  
Phil Jackson ◽  
Wolfgang H. Goldmann ◽  
...  
Keyword(s):  
Wound Healing ◽  
Phosphate Glass ◽  
Antibacterial Properties ◽  
Glass Fibres

Correction for ‘Ga and Ce ion-doped phosphate glass fibres with antibacterial properties and their composite for wound healing applications’ by Agata Łapa et al., J. Mater. Chem. B, 2019, DOI: 10.1039/c9tb00820a.

scholarly journals Antibacterial-Integrated Collagen Wound Dressing for Diabetes-Related Foot Ulcers: An Evidence-Based Review of Clinical Studies

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2168
Author(s):  
Ibrahim N. Amirrah ◽  
Mohd Farhanulhakim Mohd Razip Wee ◽  
Yasuhiko Tabata ◽  
Ruszymah Bt Hj Idrus ◽  
Abid Nordin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Clinical Trials ◽  
Clinical Studies ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Gentian Violet ◽  
Antibacterial Properties ◽  
Small Sample ◽  
Wound Dressings ◽  
Sample Sizes

Diabetic foot ulcer (DFU) is a chronic wound frequently delayed from severe infection. Wound dressing provides an essential barrier between the ulcer and the external environment. This review aimed to analyse the effectiveness of antibacterial collagen-based dressing for DFU treatment in a clinical setting. An electronic search in four databases, namely, Scopus, PubMed, Ovid MEDLINE(R), and ISI Web of Science, was performed to obtain relevant articles published within the last ten years. The published studies were included if they reported evidence of (1) collagen-based antibacterial dressing or (2) wound healing for diabetic ulcers, and (3) were written in English. Both randomised and non-randomised clinical trials were included. The search for relevant clinical studies (n) identified eight related references discussing the effectiveness of collagen-based antibacterial wound dressings for DFU comprising collagen impregnated with polyhexamethylene biguanide (n = 2), gentamicin (n = 3), combined-cellulose and silver (n = 1), gentian violet/methylene blue mixed (n = 1), and silver (n = 1). The clinical data were limited by small sample sizes and multiple aetiologies of chronic wounds. The evidence was not robust enough for a conclusive statement, although most of the studies reported positive outcomes for the use of collagen dressings loaded with antibacterial properties for DFU wound healing. This study emphasises the importance of having standardised clinical trials, larger sample sizes, and accurate reporting for reliable statistical evidence confirming DFU treatment efficiency.

A facile and large-scale synthesis of a PVA/chitosan/collagen hydrogel for wound healing

2020 ◽  
Vol 44 (47) ◽  
pp. 20776-20784
Author(s):  
XiaoHui Zhang ◽  
Zhengrong Yin ◽  
Yuqing Guo ◽  
Haofei Huang ◽  
JianYe Zhou ◽  
...  
Keyword(s):  
Wound Healing ◽  
Large Scale ◽  
Antibacterial Properties ◽  
Freezing And Thawing ◽  
Collagen Hydrogel ◽  
Large Scale Synthesis

PVA/chitosan/collagen hydrogel prepared by simple freezing and thawing method has high antibacterial properties and excellent wound healing ability.

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