scholarly journals Levels of some trace metals and their potential health risks in water from Kwadon boreholes, Gombe State, Nigeria

2018 ◽  
Vol 10 (1) ◽  
pp. 654
Author(s):  
A.U. Maigari ◽  
M Umar Maryam ◽  
M.S. Sambo
2017 ◽  
Vol 24 (17) ◽  
pp. 14847-14856 ◽  
Author(s):  
Yan Wu ◽  
Yihui Zhou ◽  
Yanling Qiu ◽  
Da Chen ◽  
Zhiliang Zhu ◽  
...  

Abstract The present study measured concentrations of Cr, Ni, Cu, Zn, As, Cd, Sb, and Pb in surface sediments and two benthic invertebrate species (Anodonta woodiana and Bellamya aeruginosa) collected from Dianshan Lake, located in the Yangtze River Delta. The Dianshan Lake acts as one of the most important drinking water sources to Shanghai, the biggest city in China. Concentrations of trace metals and metalloids ranged from 0.04 mg/kg for Cd to 288.0 mg/kg for Zn. Substantial bioaccumulation in invertebrates was observed for Zn and Cu based on the biota-sediment accumulation factor (BSAF) measurements. The results revealed that concentrations of metals and metalloids in sediments from Dianshan Lake were at the lower end of the range of levels found in other regions of China. The assessment of three significantly inter-related evaluation indices, including the geo-accumulation Index (Igeo), potential ecological risk factor (Eri), and mean probable effect concentration quotients (Qm-PEC), suggested that sediment-associated trace elements exhibited no considerable ecological risks in the studied watershed. However, the target hazard quotient and hazard index analysis suggested that selected elements (particularly As) accumulation in edible tissues of benthic invertebrates could pose potential health risks to local populations, especially fishermen. Given that wild aquatic organisms (e.g., fish and bivalves) constitute the diet of local populations as popular food/protein choices, further investigations are needed to better elucidate human health risks from metal and metalloid exposure via edible freshwater organisms.


2020 ◽  
Vol 10 (27) ◽  
pp. 200905
Author(s):  
Md. Al Amin ◽  
Md. Estiar Rahman ◽  
Sahadat Hossain ◽  
Mahmudur Rahman ◽  
Mohammad Moshiur Rahman ◽  
...  

Background. The occurrence of high levels of trace metals in foodstuffs represents a significant threat to human health. Vegetables grown in metal-contaminated soil or irrigated with wastewater can accumulate metals and bioaccumulate in the food chain affecting animals and humans. Objectives. The present study aimed to measure the levels of lead (Pb), cadmium (Cd), chromium (Cr) and cobalt (Co) in common vegetables grown in the industrial areas of Savar, Bangladesh, and to determine their potential health risks. Methods. Five vegetables species: jute ( Corchorus capsularis), red amaranth ( Amaranthus gangeticus), okra ( Abelmoschus esculentus), zucchini ( Luffa aegyptiaca) and stem amaranth ( Amaranthus viridis) were sampled randomly from agricultural fields across each study site. Vegetable samples were digested in a microwave digestion system (Berghof Microwave MWS-2, Germany). Metal concentrations were determined using an atomic absorption spectrophotometer (AA-7000, Shimadzu Corporation, Japan). Results. The range of Pb, Cd, Cr and Co in analyzed vegetables was 0.643–3.362, 0.041–0.049, 1.681–2.431 and 1.612–2.492 mg/kg, respectively. The target hazard quotient (THQ) of Pb in zucchini and stem amaranth and the THQs of Cr in all analyzed vegetables was greater than one. The target carcinogenic risk (TCR) of Pb and Cd for all analyzed vegetables was in the unacceptable range. In all vegetable samples, lead content was detected to be higher than the maximum permissible limits. The THQ values indicate the possibility of non-carcinogenic health risk through consumption of these vegetables. In addition, the TCR values of Pb and Cd indicate a lifetime carcinogenic health risks to consumers. Conclusions. Consumption of vegetables grown in this area may pose long-term health risks. Competing Interests. The authors declare no competing financial interests.


2021 ◽  
Vol 6 (4) ◽  
pp. 508-518
Author(s):  
Vedaste Munyeshury ◽  
Eutilerio Felizardo Crisino Chaúque ◽  
Noor Jehan Gulamussen ◽  
Jaime Silvestre Mandlate ◽  
Heidi Richards ◽  
...  

Due to the toxicity of trace metals and the propensity of fishes to bioaccumulate metals in their tissues, we investigated the concentrations of arsenic (As), cadmium (Cd), copper (Cu), iron (Fe), lead (Pb), mercury (Hg), and zinc (Zn) in the muscles of tilapia (Oreochromis mossambicus) and catfish (Chrysichthys nigrodidatatus) collected from open markets in Mozambique. Fe and Hg were the most and least bioaccumulated metals in the fishes, respectively. One-way ANOVA showed significant differences between sites for the analytes. Furthermore, we estimated the possible health risks (estimated daily intake (EDI), target hazard quotient (THQ), and maximum allowable consumption rate (CRlim)) associated with fish consumption. The concentrations of As, Cd, and Pb exceeded the recommended maximum permissible limits (MPL) in fish samples, ranging between 5.65 – 12.7, 1.05 – 12.9, and 1.88 – 6.45 mgkg-1, respectively, whereas values lower than MPL viz. 5.25 – 18.9, ND – 0.033, and 30.8 – 52.3 mgkg-1 were observed for Cu, Hg, and Zn, respectively. Similarly, the EDI (mgkg-1day-1) were below the provisional tolerable daily intake (PTDI) with decreasing order: Fe >Zn >Cu >As >Cd >Pb>Hg. However, the THQ (mg kg-1) was slightly > 1 for As and Cd in some samples. Moreover, the CRlim (kg day-1) showed a decreasing order of Hg >Fe >Zn >Pb> Cu >Cd >As. Generally, consumers are susceptible to health hazards associated with As and Cd. Hence, regular toxicological monitoring of the fishes from the study area is imperative.


Cells ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 940
Author(s):  
Linda Rubinstein ◽  
Amber M. Paul ◽  
Charles Houseman ◽  
Metadel Abegaz ◽  
Steffy Tabares Ruiz ◽  
...  

Long duration spaceflight poses potential health risks to astronauts during flight and re-adaptation after return to Earth. There is an emerging need for NASA to provide successful and reliable therapeutics for long duration missions when capability for medical intervention will be limited. Clinically relevant, human placenta-derived therapeutic stromal cells (PLX-PAD) are a promising therapeutic alternative. We found that treatment of adult female mice with PLX-PAD near the onset of simulated weightlessness by hindlimb unloading (HU, 30 d) was well-tolerated and partially mitigated decrements caused by HU. Specifically, PLX-PAD treatment rescued HU-induced thymic atrophy, and mitigated HU-induced changes in percentages of circulating neutrophils, but did not rescue changes in the percentages of lymphocytes, monocytes, natural killer (NK) cells, T-cells and splenic atrophy. Further, PLX-PAD partially mitigated HU effects on the expression of select cytokines in the hippocampus. In contrast, PLX-PAD failed to protect bone and muscle from HU-induced effects, suggesting that the mechanisms which regulate the structure of these mechanosensitive tissues in response to disuse are discrete from those that regulate the immune- and central nervous system (CNS). These findings support the therapeutic potential of placenta-derived stromal cells for select physiological deficits during simulated spaceflight. Multiple countermeasures are likely needed for comprehensive protection from the deleterious effects of prolonged spaceflight.


2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Trishala Gopikrishna ◽  
Harini Keerthana Suresh Kumar ◽  
Kumar Perumal ◽  
Elavarashi Elangovan

Abstract Purpose Fermented soybean foods (FSF) is popularly consumed in the South-East Asian countries. Bacillus species, a predominant microorganism present in these foods, have demonstrated beneficial and deleterious impacts on human health. These microorganisms produce bioactive compounds during fermentation that have beneficial impacts in improving human health. However, the health risks associated with FSF, food pathogens, biogenic amines (BAs) production, and late-onset anaphylaxis, remain a concern. The purpose of this review is to present an in-depth analysis of positive and negative impacts as a result of consumption of FSF along with the measures to alleviate health risks for human consumption. Methods This review was composed by scrutinizing contemporary literature of peer-reviewed publications related to Bacillus and FSF. Based on the results from academic journals, this review paper was categorized into FSF, role of Bacillus species in these foods, process of fermentation, beneficial, and adverse influence of these foods along with methods to improve food safety. Special emphasis was given to the potential benefits of bioactive compounds released during fermentation of soybean by Bacillus species. Results The nutritional and functional properties of FSF are well-appreciated, due to the release of peptides and mucilage, which have shown health benefits: in managing cardiac disease, gastric disease, cancer, allergies, hepatic disease, obesity, immune disorders, and especially microbial infections due to the presence of probiotic property, which is a potential alternative to antibiotics. Efficient interventions were established to mitigate pitfalls like the techniques to reduce BAs and food pathogens and by using a defined starter culture to improve the safety and quality of these foods. Conclusion Despite some of the detrimental effects produced by these foods, potential health benefits have been observed. Therefore, soybean foods fermented by Bacillus can be a promising food by integrating effective measures for maintaining safety and quality for human consumption. Further, in vivo analysis on the activity and dietary interventions of bioactive compounds among animal models and human volunteers are yet to be achieved which is essential to commercialize them for safe consumption by humans, especially immunocompromised patients.


Toxin Reviews ◽  
2021 ◽  
pp. 1-13
Author(s):  
Masumeh Taheri ◽  
Mohamad Hosein Mahmudy Gharaie ◽  
Jalil Mehrzad ◽  
Michael Stone ◽  
Reza Afshari

Sign in / Sign up

Export Citation Format

Share Document