scholarly journals Phytochemistry and in vitro antiplasmodial properties of aqueous and ethanol stem bark extracts of Jatropha curcas (Physic Nut)

2018 ◽  
Vol 10 (2) ◽  
pp. 159 ◽  
Author(s):  
Abdullahi A. Imam ◽  
Amina Shehu ◽  
Ibrahim A. Khalil ◽  
Hadiza Abdullahi
Keyword(s):  
2014 ◽  
Vol 13 (2) ◽  
pp. 265-273 ◽  
Author(s):  
Mahalakshmi Ravi ◽  
Eganathan Palanisami ◽  
Parida Ajay

2015 ◽  
Vol 176 (3) ◽  
pp. 892-902 ◽  
Author(s):  
Jefferson da Luz Costa ◽  
André Luís Lopes da Silva ◽  
Mário César Jucoski Bier ◽  
Gilvano Ebling Brondani ◽  
André Luiz Gollo ◽  
...  

2017 ◽  
Author(s):  
Ahmed Ibrahim Alrashid Yousif ◽  
Ankardiansyah Pandu Pradana ◽  
Muhammad Firdaus Oktafiyanto ◽  
Diana Putri ◽  
Abdul Munif

Radopholus similis is a nematode that infects many plantation crops. Infected plant roots by nematodes will show necrosis symptoms, then rot due to infection of secondary pathogens. Control of R. similis that is effective, environmentally friendly, and easy to be performed by the farmers is the key to success in reducing losses by this nematode. Extract of physic nut has been recognized to be effective in controlling some important pests, but there is currently no reports of its effectiveness in controlling R. similis. This study aimed to determine the effectiveness of leaves and fruit steeping of physic nut for in vitro control of R. similis. A total of 1:10 (w/v) leaves and fruit of physic nut were steepped, then filtered by a 500 mesh sieve. Steeping was then dripped into a suspension containing 40 R. similis. Twenty-four hours after treatment, the number of dead nematodes was observed. The leaves steeping of physic nut could kill up to 70% of R. similis. Mortality of R. similis treated with steeping of physic nut seeds reached 76.25%. Both steeping applications did not cause damage to the body of nematodes, thus it is presumably that the mortality was due to toxic compounds.


Author(s):  
Noorzaid Muhamad ◽  
Syahirah Sazeli ◽  
Resni Mona ◽  
Jannathul Firdous

The anthelmintic resistance has limited the control of gastrointestinal nematodes of small ruminants and thus has awakened interest in the study of plants extract as a source of anthelmintics. These experiments were carried out to evaluate the in vitro efficacy of Jatrophacurcas latex extract against Haemonchuscontortus larval motility. To evaluate the larvicidal activity, H.contortus L3 were incubated with the extracts with varying concentration of 5 mg/mL, 10 mg/mL, 15 mg/mL and 20 mg/mL at 27°C for 48, 72 and 96 hrs. The results were subjected to the Kruskal-Wallis test (P less than 0.05). The extracts showed dose-dependent larvicidal effects. These results suggest that J.curcas can be used to control gastrointestinal nematodes of small ruminants.


Author(s):  
Kelly Oriakhi ◽  
Collins U. Ibeji ◽  
Emmanuel E. Essien ◽  
Nkeiruka Eluehike ◽  
Kissinger Orumwensodia ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (24) ◽  
pp. 6034
Author(s):  
Wen-bing Ding ◽  
Rui-yuan Zhao ◽  
Guan-hua Li ◽  
Bing-lei Liu ◽  
Hua-liang He ◽  
...  

Five new cyclic diarylheptanoids (platycary A–E, compounds 1–5) and three previously identified analogues (i.e., phttyearynol (compound 6), myricatomentogenin (compound 7), and juglanin D (compound 8)) were isolated from the stem bark of Platycarya strobilacea. The structures of these compounds were determined using NMR, HRESIMS, and electronic circular dichroism (ECD) data. The cytotoxicity of compounds 1–5 and their ability to inhibit nitric oxide (NO) production, as well as protect against the corticosterone-induced apoptosis of Pheochromocytoma (PC12) cells, were evaluated in vitro using the appropriate bioassays. Compounds 1 and 2 significantly inhibited the corticosterone-induced apoptosis of PC12 cells at a concentration of 20 μΜ.


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