Prevalence of adverse drug reactions in adult patients on anti-retrovirals at Kenyatta National Hospital, Comprehensive Care Centre

Background: Recent increases in access to HAART have made the management of drug toxicities an increasingly crucial component of HIV care in developing countries. The aim of this study was to determine prevalence of antiretroviral ther- apy adverse drug reactions and associated factors among HIV-infected adult patients at Nigist Eleni Mohammed memorial hospital. Methods: A cross sectional study was conducted by retrospective review of patients’ medical records. From a total 721 adult patient records, 231 patients record were selected by simple random sampling technique. The study was conducted April15-25, 2015.The association between dependent and independent variables was measured by using OR at 95% CI. P-value <0.05 was considered as statistically significant. Result: About 53(22.9%) patients developed ADRs (adverse drug reactions). Female (AOR=2.72, CI=1.177-6.30), patients with WHO stage III and IV (AOR= 13.06, CI=4.17- 40.90) were found more likely to develop ADRs. Commonly identified ADRs were fatigue (18.1%), diarrhea (7.7%), nausea (6.5%), headache (3.6%) and anemia (2%). Conclusion: Nearly one in five patients develop ADRs. Sex of respondents, WHO stage and functional status were asso- ciated with ADRs. The health care providers should give due attention to ambulatory, bedridden, and WHO stage III and IV patients. Keywords: ART; HIV; AIDS; Ethiopia.

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Nurses’ and Patients’ Perceptions on the Importance of Nurse-Caring Behaviors: A Study at the Surgical Wards of Kenyatta National Hospital, Nairobi

International Journal for Human Caring ◽

10.20467/1091-5710.19.2.55 ◽

2015 ◽

Vol 19 (2) ◽

pp. 55-61

Author(s):

Everlyne Ogugu, ◽

Theresa Odero, ◽

Antony Ong’any, ◽

Miriam Wagoro,

Keyword(s):

Descriptive Study ◽

Adult Patients ◽

National Hospital ◽

Cross Sectional ◽

Caring Behaviors ◽

Know How ◽

Kenyatta National Hospital ◽

Nurse Caring

A cross-sectional descriptive study was done at surgical wards of Kenyatta National Hospital to compare nurses’ and patients’ perceptions on importance of nurse-caring behaviors. Data were collected from 182 adult patients and 127 nurses. The most important nurse-caring behaviors as ranked by patients were give me treatments and medications on time and help me with my care until am able to do it for myself. Nurses ranked treat the patient as an individual and know how to give injections as the 2 most important nurse-caring behaviors.

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Awareness of adverse drug reactions reporting among doctors in a tertiary care centre

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20163267 ◽

2016 ◽

pp. 2236-2239

Author(s):

Laila V. ◽

Hemalatha T.

Keyword(s):

Adverse Drug Reactions ◽

Tertiary Care ◽

Care Centre ◽

Drug Reactions ◽

Tertiary Care Centre

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STUDY TO EVALUATE SEVERE ADRS IN A TERTIARY CARE TEACHING HOSPITAL

International Journal of Current Pharmaceutical Research ◽

10.22159/ijcpr.2017v9i5.22137 ◽

2017 ◽

pp. 55-58

Author(s):

A. R. Malahat ◽

C. Deepa Latha ◽

Sudhakar K. ◽

Deepika Baloju ◽

G. Vijayalakshmi

Keyword(s):

Adverse Drug Reactions ◽

Teaching Hospital ◽

Prospective Observational Study ◽

Healthcare Professionals ◽

Tertiary Care ◽

Care Centre ◽

Drug Reactions ◽

Tertiary Care Centre ◽

Tertiary Care Teaching Hospital ◽

Care Teaching

Objective: This study attempts to analyze the severe ADRs in a tertiary care centre and assess their seriousness, outcome, causality and severity. We emphasize on the need for reporting of ADRs by all healthcare professionals as it will reduce the burden of morbidity due to drugs and ensure better and more efficient healthcare. To analyse and evaluate the severe ADVERSE DRUG REACTIONs reported from various departments in a Tertiary care Teaching hospital.Methods: It is a prospective observational study that was carried out over a period of 6 mo (from July 2016 to December 2016) to assess the percentage of severe adverse drug reactions reported to the Pharmacovigilance cell of a tertiary care teaching hospital. The data collected included patientâ€™s demographic details, presenting complaints, clinical diagnosis and details of the drug(s) prescribed. The data was analysed for causality (as per the WHO-UMC scale) and severity (as per Hartwig and Siegel scale).Results: Out of 64 ADRs reported, 17 were serious. The majority of serious ADRs were categorized as probable (82.35%), whilst 1(5.8%) was categorized as possible and 2(11.76%) as certain in nature. The criteria for the majority of serious ADRs were hospitalization (%) followed by intervention to prevent permanent impairment or damage (%).Conclusion: The highest percentage of severe cases was reported with Antitubercular therapy (23.5%) followed by analgesics (23%) and anti epileptic agents (17.6%).

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