scholarly journals Seroprevalence of rubella-specific IgM and IgG antibodies among pregnant women in a Catholic Hospital in Yaoundé, Cameroon

2018 ◽  
Vol 12 (3) ◽  
pp. 1123
Author(s):  
Anna Aret Eno ◽  
Louise Stéphanie Makemgue ◽  
Daves Stéphane Tonye III ◽  
Cheikh Saad Bouh Boye ◽  
Abdoulaye Seck ◽  
...  
2021 ◽  
Vol 16 (10) ◽  
pp. 3-7
Author(s):  
Tonya Robinson ◽  
Nicole Pozzi ◽  
Saeed Jortani

Awareness of SARS-COV-2 IgG may contribute to the management of asymptomatic RT PCR COVID-19 positive pregnant women, their newborns, and future vaccination practices. Objective: Characterize COVID testing results of asymptomatic COVID-19 positive pregnant women and their infants. Our assumption/hypothesis maintained that all infants born to asymptomatic COVID-19 positive mothers would have detectable SARS-CoV-2 specific IgG. Study Design: Retrospective chart review. Clinical demographics/COVID-19 testing of maternal/infant dyads were reviewed/collected for reporting purposes. Setting: Center for Women and Infants (CWI), University of Louisville Hospital, Louisville, KY Participants: Asymptomatic COVID-19 positive pregnant women/infant dyads admitted to the CWI between June 2020 to February 2021. Results: 36 COVID-19 positive asymptomatic mother/37 infant dyads (one set of twins) reviewed. 38% of the mother/infant dyads were positive for SARS-CoV-2 IgG, while 27% of mother/infant dyads were negative for IgG. A COVID-19 positive mother of twins was IgG negative, but both twins were positive. Two mothers in this study group had developed significant COVID-19 disease at 28w4d gestation and 34w0d gestation. Both required intensive care but recovered, and their pregnancies were maintained until 37w4d and 39w3d gestation, respectively. By the time of delivery, both mothers had negative COVID-19 RT PCR testing, but both infants were positive for SARS-CoV-2 IgG antibodies. COVID-19 RT PCR testing on both of these infants at 24 and 48 hours of age was negative. Conclusion: SARS-CoV-2 IgG is passively transferred to the infant during pregnancy of asymptomatic positive COVID-19 mothers however appears variable and/or possibly based on the ability of IgG detection with current testing. Further investigation of the immune system’s response to the SARS-CoV-2 virus during pregnancy can direct future management/treatment during pregnancy, especially in the wake of vaccination for the virus during pregnancy and emerging variants.


Author(s):  
Maryam Aminu ◽  
Okikiola Olajide ◽  
Abdullahi, Jibril Randawa ◽  
Daniel, Stephen Adejo

Author(s):  
Okonko, I. O. ◽  
Ijandipe, L. A. ◽  
Ilusanya, A. O. ◽  
Donbraye-Emmanuel, O. B. ◽  
Ejembi, J. ◽  
...  

2019 ◽  
pp. 1-6
Author(s):  
Seema Malav ◽  
Bharti Malhotr

Background : The aim of this study were assess the susceptible pregnant women for vaccine preventable infection like rubella, mumps, measles and varicella viruses. Infection of mothers with these viruses during pregnancy can be serious. They can cause congenital infections, miscarriage, stillbirth and death of fetuses. Material and Method : This study is cross sectional. To determine the presence of IgG antibodies for rubella, mumps, measles and varicella viruses, blood samples were collected, stored at -700 c. Serum was separated for detection of IgG antibodies for these viruses by using enzyme linked immunosorbant assay. Results : Of 277 samples evaluated for IgG antibodies. Susceptibility Of pregnant women for rubella, mumps measles and varicella viruses were 7.6%, 17.6%,7.2% and 19.5% respectively. Susceptibility rates for rubella and mumps were higher in rural population as compares to urban while for varicella urban population was more susceptible, but it was not statistically signicant. No correlation could be observed in susceptibility to different to different viruses and their education status and age of patients, but youngest age group was most susceptible to varicella and oldest group to rubella. Primigravida were more susceptible to rubella and varicella while multigravida were more susceptible to mumps and measles. Conclusion : Majority of the pregnant women had protective levels of IgG antibody although susceptibility to rubella, mumps measles and varicella were low. Intensication of MMRV immunization of all females of child-bearing age is advocated.


2010 ◽  
Vol 2 (2) ◽  
pp. 156-159 ◽  
Author(s):  
Mohammed-Durosinlorun Amina ◽  
Shittu Oladapo ◽  
Sadauki Habib ◽  
Olayinka Adebola ◽  
Kolawole Bimbo ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e110700 ◽  
Author(s):  
Manola Comar ◽  
Connie Wong ◽  
Mauro Tognon ◽  
Janet S. Butel

2007 ◽  
Vol 122 (4) ◽  
pp. 499-506 ◽  
Author(s):  
Barbara Watson ◽  
Rachel Civen ◽  
Meredith Reynolds ◽  
Karl Heath ◽  
Dana Perella ◽  
...  

Objective. The purpose of this study was to assess the validity of self-reported history for varicella disease relative to serological evidence of varicella immunity in pregnant women attending antenatal care at clinics located in two diverse geographical locations in the U.S. (Antelope Valley, California, and Philadelphia) with high varicella vaccination coverage. Methods. Pregnant women attending prenatal care appointments who needed blood drawn as part of their routine care were eligible to participate. Self-reported varicella disease history was obtained via questionnaire. Varicella serostatus was determined using a whole-cell enzyme-linked immunosorbent assay to test for varicella zoster virus-specific immunoglobulin G (VZV IgG) antibodies. Results. Of the 309 study participants from Antelope Valley and the 528 participants from Philadelphia who self-reported having had chickenpox disease, 308 (99.7%; 95% confidence interval [CI]: 98.2, 100) and 517 (97.9%; 95% CI: 96.3, 99.0), respectively, had serological evidence of immunity to varicella. Only 6.8% (95% CI: 3.9, 11.0) and 17.4% (95% CI: 13.1, 22.5) of women who self-reported having a negative or uncertain varicella disease history in Antelope Valley and Philadelphia, respectively, were seronegative for varicella antibodies. Conclusion. Despite the dramatic changes in the epidemiology of varicella that have occurred since 1995 due to the introduction and subsequent widespread use of the varicella vaccine, self-reported history of varicella continues to be a strong predictor of VZV IgG antibodies in pregnant women. Negative or uncertain history remains poorly predictive of negative serostatus.


Sign in / Sign up

Export Citation Format

Share Document