scholarly journals SCREENING OF PREGNANT WOMEN FOR PRESENCE OF IGG ANTIBODIES FOR RUBELLA, MUMPS, MEASLES AND VARICELLA VIRUSES IN TERTIARY CARE HOSPITAL , JAIPUR

2019 ◽  
pp. 1-6
Author(s):  
Seema Malav ◽  
Bharti Malhotr

Background : The aim of this study were assess the susceptible pregnant women for vaccine preventable infection like rubella, mumps, measles and varicella viruses. Infection of mothers with these viruses during pregnancy can be serious. They can cause congenital infections, miscarriage, stillbirth and death of fetuses. Material and Method : This study is cross sectional. To determine the presence of IgG antibodies for rubella, mumps, measles and varicella viruses, blood samples were collected, stored at -700 c. Serum was separated for detection of IgG antibodies for these viruses by using enzyme linked immunosorbant assay. Results : Of 277 samples evaluated for IgG antibodies. Susceptibility Of pregnant women for rubella, mumps measles and varicella viruses were 7.6%, 17.6%,7.2% and 19.5% respectively. Susceptibility rates for rubella and mumps were higher in rural population as compares to urban while for varicella urban population was more susceptible, but it was not statistically signicant. No correlation could be observed in susceptibility to different to different viruses and their education status and age of patients, but youngest age group was most susceptible to varicella and oldest group to rubella. Primigravida were more susceptible to rubella and varicella while multigravida were more susceptible to mumps and measles. Conclusion : Majority of the pregnant women had protective levels of IgG antibody although susceptibility to rubella, mumps measles and varicella were low. Intensication of MMRV immunization of all females of child-bearing age is advocated.

2020 ◽  
Author(s):  
Dr. Animesh Ray ◽  
Dr. Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Dr. Gaurav Batra ◽  
...  

BACKGROUND Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India OBJECTIVE The primary objective of this study is to estimate the seroprevalence of SARS-CoV-2 antibody among patients admitted to the Medicine ward and ICU METHODS This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the ELISA method RESULTS A total of 212 hospitalized patients were recruited in the study with mean age (±SD) of 41.2 (±15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8%patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity CONCLUSIONS Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21)


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ishara P. Premathilake ◽  
Praveena Aluthbaduge ◽  
Channa P. Senanayake ◽  
Renuka Jayalatharachchi ◽  
Sirithilak Gamage ◽  
...  

Author(s):  
Nitin A. Lodha

Background: Antenatal care is the care of a woman during pregnancy. The primary aim of antenatal care is to achieve at the end of pregnancy a healthy mother and a healthy baby. To improve maternal health, barriers which limit access to quality maternal health services must be identified and addressed at all levels of health system. Objectives were to determine demographic and obstetric factors affecting utilization of ANC service and prevalence of anaemia among pregnant women.Methods: This is cross-sectional descriptive study carried out in tertiary care hospital, using structured questionnaire, interviews were conducted with married pregnant women age between 18-45 years, who visited ANC clinic. Total 170 pregnant women visited hospital during a period was included in study. Data was analysed using MS excel and Epi info. Chi –square test was applied.Results: Maximum number of study subjects (42.9%) from age 23-27 years. 66.5% were Hindu, 56.5% study subjects from joint family. 14.7% were illiterate. 45.3% were primigravida, 54.7% were multigravida. 71.1% study subjects were from third trimester of pregnancy. 94.7% were taken at least one dose of Tetanus Toxoids. Iron folic acid tablets were taken by 87.6%. Prevalence of anaemia was 55.8%.Conclusions: Majority of pregnant women came for antenatal check-up, but regularity was not seen in most of cases. The presence study has brought out no significant socio-cultural barrier like women’s literacy, socio economic class and parity of women affecting the utilization of services.


2015 ◽  
Vol 1 (1) ◽  
pp. 3-7
Author(s):  
Fatema Nusrat ◽  
K.M. Shahidul Islam ◽  
S.M. Shamsuzzaman ◽  
Md. Abdullah Yusuf ◽  
Aleya Farzana ◽  
...  

Background: Antibiotic sensitivity pattern of Neisseria gonorrhoae is changing frequently. Objective: The purpose of the present study was to see the antibiotic sensitivity pattern of Neisseria gonorrhoae isolated from women presented with cervicitis.Methodology: This cross sectional study.carried out in the Department  of Microbiology at Dhaka Medical College, Dhaka from July 2011 to December 2012 for a period of one and half year. All the women presented with or without the clinical features of  cervicitis at child bearing age (15 to 49 yrs) with or without pregnancy were enrolled as study population. Endocervical swabs were collected  for Gram staining, culture, biochemical test from clinically diagnosed  patients of cervicitis for presumptive identification of Neisseria gonorrhoeae. The isolates with presumptive identification were confirmed by rapid carbohydrate utilization test (RCUT), which differentiates  N.gonorrhoeae from other Neisseria. Antimicrobial susceptibility test was done according CLSI guideline. Result: A total 245 females were recruited of which N. gonorrhoeae were detected from 39(15.9%) cases. Among 39 positive cases of gonococcal cervicitis, 19 (48.71%) were detected in the age group of 21-30 years. 56.41% were sensitive and 30.76% were resistant to ceftriaxone. Similarly 51.28% were sensitive and 23.07% were resistant to cefuroxime; 23.07% sensitive, 30.76% moderately sensitive and 46.15% resistant to ciprofloxacin. Conclusion: Gonococcal cervicitis is found in a high frequency rate with a reduced sensitivity to antibiotics especially ciprofloxacin, second and third generation cephalosporins.Bangladesh J Infect Dis 2014;1(1):3-7


2020 ◽  
Vol 58 (227) ◽  
Author(s):  
Jyotshna Sharma ◽  
Sanjeeb Tiwari

Introduction: The sedentary lifestyle of women and change in their food habits has a significantrole in developing diabetes in pregnancies. This leads to an increased chance of fetal cardiacabnormality born by a mother with gestational diabetes and pre-existing diabetes. The objectiveof the study is to find out the prevalence of abnormal fetal echocardiography in gestational andpre-existing diabetic pregnant women at a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted among 104 diabetic pregnantwomen in a tertiary care hospital from April 15, 2017, to April 14, 2018. Ethical approvalwas obtained from the institutional review committee. The convenient sampling method wasused. The patients who were diagnosed as gestational diabetes and diabetic before pregnancywere included in the study. Fetal echocardiography was mainly done at a gestational age of22-32 weeks depending upon the time of diagnosis of gestational diabetes and for pre-diabeticwomen, fetal echocardiography was done at 24-26 weeks of gestation. Statistical analysis wasdone using the Statistical Package of the Social Sciences version 20. Results: Among 104 patients, 16 (15.38%) patients had abnormal fetal echocardiography.Eighty-three (79.81%) were gestational diabetics, 21 (20.19%) were pre-existing diabeticwomen. Among 83 gestational diabetes, 7 (8.4%) had abnormal echo finding and among 21pre-existing diabetics, 9 (42.8%) had abnormal echo finding. Conclusions: There was an increased chance of fetal cardiac malformation in gestational diabeticand pre-existing diabetics diabetic especially in an uncontrolled glycemic state. And, if theywere diagnosed prenatally, clinical outcomes for both mother and fetus would have been better.


2021 ◽  
Vol 15 (10) ◽  
pp. 3370-3374
Author(s):  
Syeda Fariha Hussain ◽  
Shazia Aftab ◽  
Huma Baloch ◽  
Naila Qamar ◽  
Maryam Masood ◽  
...  

Background: Female population can be affected by various psychological factors that can have adverse effects on the woman’s mental health. Pandemics are one such times which can have negative effect on the mental health. Therefore, this study was conducted to determine the status of depression and anxiety and factors associated with it in the female population (pregnant and non-pregnant women) during the outbreak of COVID-19. Methods: This descriptive-analytical cross-sectional study was performed on 345 women coming to a tertiary care hospital in Karachi, Pakistan. The data was collected using the socio-demographic characteristics questionnaire and the GAD-7 and PHQ-9 questionnaires. Regression analysis was done to determine the association between various factors with depression and anxiety. Results: Mean age of the participants was 27.9 years Depression and anxiety symptoms were observed in 32.7, 32.7, and 43.9% of the participants, respectively The mean score of depression was found to be 3.72 (3.80) whereas of anxiety was 3.5 (4.006). The overall prevalence of depression was 30.5% and that of anxiety was 18.55%, with varying degrees from mild to severe. Conclusions: Females in general and pregnant women specifically need special attention of the health care policy makers and this group should be given importance especially in times of such pandemics and all necessary measures should be taken to provide mental and psychological support. Keywords: COVID-19, Pregnancy, Prevalence, Depression, Anxiety, Stress


2021 ◽  
Vol 15 (10) ◽  
pp. 3137-3139
Author(s):  
Mona Fatima ◽  
Urooj Naz ◽  
Aruna Kumari Hira ◽  
Aneela Habib ◽  
Prof Sarah Kazi ◽  
...  

Objectives: To determine the frequency of preterm labour in association with interpregnancy interval among pregnant women visiting tertiary care Hospital. Subject and Methods: This prospective cross-sectional study was performed at Unit-I, Obstetrics and Gynaecology Department, Civil Hospital Karachi; from June to November 2020. A total of 190 women with singleton pregnancy confirmed by ultrasound were included. After taking detailed medical history regarding previous fetal death and C-section was recorded either patient goes into preterm labour or not and confirmed by history for short and prolong interpregnancy interval (IPI). Data was collected by pre-designed study proforma. Results: The average age of study subjects was 26.27±4.07 years. The frequency of preterm labour among the pregnant women was 51.05%. The rate of preterm was significantly higher in those women who had with short inter interpregnancy interval (p=0.0005). Conclusion: Our findings clearly show that a short interval in inter-pregnancy is a cause of premature birth. Preterm birth can also be indicated by the antenatal care visits, inter-pregnancy complications, and having a birth defect. Premature birth minimization can enhance overall newborn's health and can lead to considerable minimization of neonatal death in the future. Keywords: Preterm labor, prolong pregnancy interval, neonatal health


Author(s):  
Vruti Patel ◽  
J. D. Lakhani

Introduction: A number of adaptations happen in the anatomy, physiology and metabolic processes within the mother which aids in successful progression of the pregnancy. The different blood indices such as haemoglobin concentration, packed cell volume (PCV), red blood cell count; total WBC count etc. can be measured to evaluate haematological status in a pregnant woman. The hematological profile of the pregnant women has an impact on both pregnancy and its outcome. Anaemia in pregnancy can be leads to morbidity and mortality in mother and fetus. The current study was designed to determine the variation in status of hemoglobin and other blood indices in anemic and non-anemic pregnant women. Aims ans Objectives: 1. To study the hematological and other blood indices among pregnant women, 2. To assess the degree of anemia in pregnant women, 3. To compare the Various hematological parameters between anemic and non -anemic pregnant women. Materials and Methods: A Cross-sectional comparative descriptive survey design and quantitative approach was adopted to achieve the goal of the study. The study was conducted at the tertiary care hospital of Vadodara, Gujarat. Total 300 pregnant women were recruited and socio demographic information was collected. Hemoglobin concentration (Hb), total leucocyte count (TLC), differential leucocyte count (DLC), and platelet count, blood indices of the recruited samples were studied.Mean and SD of Haematological parameters were calculated and unpaired t-test was used to compare the pregnant anaemic women data with non-anaemic pregnant women. Results: Out of 300, 204 pregnant women were found anemic and most of the pregnant women 84% belonged to rural area. In accordance with severity of anemia, Moderate degree of anemia was found to be highest (41%) in anemic pregnant women. Comparison of non - anaemic pregnant women with anaemic pregnant women shows significant changes in haematological parameters (p <0.05). Conclusion: It can be concluded that there is significant changes in hematological parameters in each trimesters of pregnancy as well compare to non-anemic to anemic pregnant women. Most of the hematological changes occur in order to physiological adaptation of pregnancy but abnormal status of Haemoglobin and other blood indices cause adverse outcome of the pregnancy.


Author(s):  
Indresh Gupta ◽  
Anindita Mandal

Background: Antenatal care is an umbrella term used to describe the medical procedures and care that are carried out during pregnancy. Every day, approximately 830 women die from preventable causes related to pregnancy and childbirth. Worldwide, the annual number of maternal deaths per 100,000 live births fell by 44% between 1990 and 2015, from approximately 385 to 216. The sub-Saharan African region accounted for an estimated 66% (201,000) of global maternal deaths, followed by southern Asia at 22% (66,000 deaths).Basically, only 5% of the world’s countries accounted for over half of maternal deaths.Methods: A cross-sectional hospital based study was conducted on 384 spouses attending antenatal OPD. Interview Schedule was conducted to assess their knowledge and attitude using a self-structured questionnaire. Knowledge score of spouses has been computed on the basis of correct response to 18 knowledge questions and by converting it to percentage score.Results: The mean knowledge score was 61.10% taken as the arithmetic average of all the scores.  Mean attitude score was very high 94.29% with small SD 3.87. The attitude of spouse towards antenatal care is found to be extremely high. The educational status (p<0.000), age (p<0.002), type of family (p<0.018) and average income earned per month (p<0.000) were statistically significant to the level of knowledge.Conclusions: The study shows that the knowledge and attitude among spouses of pregnant women about antenatal care is good.


Author(s):  
Varsha Singh ◽  
Amit Mohan Varshney ◽  
Samarjeet Kaur

Background: Ultrasound examination during pregnancy has become an integral part of antenatal care throughout the world. This technology is an important tool for the obstetricians, to reassure their patients regarding the well-being of their fetus in utero. The objective of this study was to assess the awareness of USG among pregnant women.Methods: This cross-sectional study was carried out among pregnant women attending the ANC clinic of Obstetric department of MLB Medical College Hospital, Jhansi, UP from March to May 2018. The study included 300 pregnant women and data was collected by using pre tested questionnaire.Results: The study reveals that 51.3% of participants were in the age group of 20-25 yr and 50% of them belong to upper lower class, most of them unskilled (83.4%), 63.3% of participants depicted that USG is done only to confirm the pregnancy and 81% of women considered that it is beneficial during pregnancy and 65% was known that USG can be used to determine sex of the foetus.Conclusions: Awareness regarding the uses of ultrasonography during pregnancy was found to be average. There is need to create more awareness in community about the USG uses and PCPNDT act and its provisions. There is need of creating more awareness about the safety, utility and frequency of USG during antenatal period to avoid misuse.


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