scholarly journals Clinical Profile of Paediatric Head and Neck Cancers at a Tertiary Hospital in Tanzania

2020 ◽  
Vol 3 (1) ◽  
pp. 11-20
Author(s):  
Zephania Saitabau Abraham ◽  
Enica Richard Massawe ◽  
Aveline Aloyce Kahinga ◽  
Kassim Babu Mapondella ◽  
Willybroad Augustine Massawe ◽  
...  

Background Paediatric head and neck cancers represent an important group of childhood cancers that require maximum attention at large. They are often diagnosed at advanced clinical stages at Muhimbili National Hospital (MNH). Objective To describe the clinical profile of paediatric head and neck cancers at a tertiary hospital in Tanzania Method A hospital based descriptive cross-sectional study was conducted involving 180 paediatric patients. Data were analyzed using SPSS program version 21. Results A total of 180 paediatric patients were recruited where 61.1% were males and 38.9% were females. Majority belonged to the age group 0-5 years (53.9%). A total of 10 primary anatomical sites were found with the neck (cervical lymph node) predominating (36.1%), followed by the orbit/eye (34.4%) and the least anatomical sites were oral cavity (1.1%) and parapharyngeal space (0.5%). Leukocoria (93.9%), red eye (93.9%) and orbital cellulitis (77.6%) predominated in retinoblastoma but in patients with lymphomas, predominant features were night sweats (100%), weight loss (100%) and fevers (95.8%). Conclusion The clinical profile depicted in this study appears to correlate with advanced clinical stages. Keywords: Paediatric; Head; Neck Cancers; Muhimbili; Tanzania

Author(s):  
Zephania Saitabau Abraham ◽  
Daudi Ntunaguzi ◽  
Aveline Aloyce Kahinga ◽  
Henry Swai ◽  
Siwillis Mithe ◽  
...  

<p class="abstract"><strong>Background:</strong> Head and neck cancer is the sixth most common cancer in the world and the largest burden occurs in developing countries where such burden of infectious diseases is also high. Data on the clinico-pathological profile of paediatric head and neck cancers is scarce in Tanzania. To the best of our knowledge, this is the first study in Tanzania to characterize such profile.</p><p class="abstract"><strong>Methods:</strong> A hospital based descriptive cross sectional study was conducted involving 180 pediatric patients at Muhimbili National Hospital. Data collected was analyzed using SPSS program version 21.  </p><p class="abstract"><strong>Results:</strong> A total of 180 paediatric patients were recruited where 61.1% were males with a male to female ratio of 1.57:1 and majority fell into the 0-5years age range (53.9%). Ten primary anatomical sites were found with the neck (cervical lymph node) (36.1%) predominating followed by the orbit/eye (34.4%) and the least common site was parapharyngeal space (0.5%). The neck was more affected in patients aged 6-11 years with a diagnosis of lymphomas (98.5%) whereas the orbit was affected predominantly in those aged 0-5 years (90.3%) by retinoblastoma (79%). The predominant histocytopathological variant was lymphoma (52.8%) and the least was Langerhans cell histiocytosis (0.6%). Lymphomas and retinoblastoma occurred commonly in males (70.53% and 53.06% respectively) but sarcomas showed no gender predilection. Lymphomas (32.6%) and retinoblastomas (93.9%) predominated in patients aged 6-11 years and 0-5 years respectively.</p><p><strong>Conclusions:</strong> Lymphomas, retinoblastomas and sarcomas were more predominant in paediatric patients similar to what has been reported in various reports elsewhere.</p>


2020 ◽  
pp. 172-174
Author(s):  
Aravind Reddy. Gangula ◽  
M Manasa

Snake bite is an occupational disease of farmers, plantation workers herdsmen, fishermen, snake workers and other food producers.It is therefore a medical problem that has significant implications for the nutritional and Economy of the countries. Snake envenomation is a common presentation in rural tertiary hospitals . The clinical profile of snake envenomation has been well established. However data on Electrocardiographic changes in snake envenomation particularly patients presenting to SouthIndian rural tertiary hospital are scant Aims and objectives: To study on the cardiac manifestations and electrocardiographic findings of patients with snake envenomation. Place of study : Department of General medicine,kamineni Institute of Medical sciences, Narketpally. Duration of study- sep 2018 to sep 2020. Study design – Cross sectional study. Sample size – 60. The clinical profile of snake envenomation is varied, in its severity and type of species, hence the ECG may be cheap and simple tool to detect warning signs early to initiate timely and appropriate management .


2021 ◽  
Vol 28 (04) ◽  
pp. 548-551
Author(s):  
Maria Saleem ◽  
Asim Khurshid ◽  
Amna Wajdan ◽  
Muhammad Salman Zafar

Objectives: To analyze the clinical profile, etiologies and outcome of seriously ill patients admitted in Pediatric Intensive Care Unit (PICU). Study Design: Cross Sectional study. Setting: PICU of Nishtar Medical Hospital, Multan, Pakistan. Period: January 2018 to December 2018. Material & Methods: During the study period, a total of 150 children, aged 1 to 12 years, with better prognosis and post-surgical cases requiring intensive care were registered. Age, gender, cause for hospitalization (clinical, surgical or emergency), length of PICU stay, diagnosis and outcome were recorded for all patients. Results: During the year of the study, 83 (55.3%) children were noted to be male. The mean age was 56.9+12.5 months. Mechanical ventilation was done in 62 (41.3%) patients. Major indications for admission to the PICU were respiratory disorders (21.5%), followed by sepsis (11.4%) and meningitis (8.1%). Majority, 80 (53.3%) patients improved and were shifted to ward and later discharged while 27 (18.0%) expired. Conclusion: Most of the children admitted in the PICU were male, aged below 5 years. Most common indication for admission in the PICU were respiratory disorders followed by sepsis and meningitis.


2017 ◽  
Vol 31 (1) ◽  
pp. 10-15 ◽  
Author(s):  
Saria Tasnim ◽  
Md Abidul Haque ◽  
Summyia Nazmeen

Objective (s): The objective was to explore frequency of menopause related symptoms among middle aged women and their perception about menopause,Materials and Methods: This was a cross sectional study carried during March to May 2013 among women aged 45-60 years at the out patient Department of Obstetrics and Gynaecology of a tertiary hospital using structured questionnaire. Information was sought regarding menstrual pattern, self reported menopausal symptoms and attitude towards menopausal transition. Data analysis was done using SPSS version 16.Results: Total 106 women were interviewed, The mean age of the respondents was 50.3± 53 years, and 58.5% were post menopausal and 41.5% in menopausal transition. More than half (59.4%) were illiterate, 32% were working. Common menopausal symptoms were insomnia 51.8%, body ache 44.3% and feeling sad 31.3%. Hot flush and night sweats were reported by 50% and 33% respectively. Half of them regard menopause as normal and health seeking for menopausal problems was 42.5%.Conclusion: A significant proportion of women were suffering from vasomotor and psychosomatic symptoms but most of them did not seek treatment. To ensure quality of life health needs of middle aged women should be identified and their views towards menopause incorporated in formulating services for themBangladesh J Obstet Gynaecol, 2016; Vol. 31(1) : 10-15


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Olumayowa Abimbola Oninla

Skin diseases are indicators of HIV/AIDS which correlates with WHO clinical stages. In resource limited environment where CD4 count is not readily available, they can be used in assessing HIV patients. The study aims to determine the mucocutaneous manifestations in HIV positive patients and their correlation with WHO clinical stages. A prospective cross-sectional study of mucocutaneous conditions was done among 215 newly diagnosed HIV patients from June 2008 to May 2012 at adult ART clinic, Wesley Guild Hospital Unit, OAU Teaching Hospitals Complex, Ilesha, Osun State, Nigeria. There were 156 dermatoses with oral/oesophageal/vaginal candidiasis (41.1%), PPE (24.4%), dermatophytic infections (8.9%), and herpes zoster (3.8%) as the most common dermatoses. The proportions of dermatoses were 4.5%, 21.8%, 53.2%, and 20.5% in stages 1–4, respectively. A significant relationship (using Pearson’s Chi square withPvalue<0.05) was obtained between dermatoses and WHO clinical stages. Pearson’s correlation coefficient showed a positive correlation between the number of dermatoses and the WHO clinical stages. Dermatoses can therefore serve as diagnostic and prognostic markers in resource limited settings to initiate HAART in clinical stages 3 and 4.


2021 ◽  
Vol 10 (04) ◽  
pp. 236-240
Author(s):  
Gambhir Shrestha ◽  
Bhola Siwakoti ◽  
Rashmi Mulmi ◽  
Dejkumar Gautam

Abstract Introduction Head and neck cancers (HNCs) are increasing in Nepal and have become a major public health issue. This study aims to describe the trend of HNCs in a national tertiary cancer hospital in Nepal. Methods This was a cross-sectional study with secondary data analysis conducted at B.P Koirala Memorial Hospital, Chitwan, Nepal. The data were obtained from the medical record section and included all new HNC cases registered from 2012 to 2017. Analysis was done using Statistical Package for Social Sciences version 17. Subgroup analysis was done according to age, gender, site, and year. Results A total of 4,582 new HNCs were registered, of which 3,097 (67.6%) were males and 1,482 (32.4%) were females. Lip and oral cavity cancers (46.5%) were the most common HNCs followed by tonsil and pharynx (18.0%) and larynx (15.8%). The trend of HNCs shows a steady rise in incidence with difference according to the sites. HNCs were more common among males than females except for thyroid cancer. The most common age group was 60 to 74 years. Conclusions The trend of HNCs is increasing in Nepal especially oral cancers. Awareness of risk factors, effective screening programs, and comprehensive treatment should be focused to decrease the burden of HNCs.


2021 ◽  
pp. 875647932110210
Author(s):  
Idigo Felicitas Ugochinyere ◽  
Nwankwo Sylvia Chiamaka ◽  
Abonyi Everistus Obinna ◽  
Anakwue Angel-Mary Chukwunyelu ◽  
Agbo Julius Amechi

Objective: Renal volume (RV) assessment during obstetric sonography is rarely considered in our locality. Understanding the changes in RV in both normotensive pregnant (NP) and pregnancy-induced hypertensive (PIH) women is important in making correct diagnosis regarding pregnancy outcome. This study is aimed at determining the RV in NP and PIH women and correlating RV with fetal gestational age (FGA), body mass index (BMI), and parity in NP women. Materials and Methods: This cross-sectional study involved 450 patients recruited at a Tertiary Hospital. A pilot study was done to determine the interobserver variability in RV measurement. RV was calculated using the following formula: L × W × AP × 0.523. Parity, BMI, and blood pressure were documented, while FGA was calculated as an average of FGAs obtained from the measurements of fetal biometric parameters. Results: Mean RV of PIH women was significantly higher than that of NP women ( P < .05). RV shows a positive significant relationship with BMI and FGA, while it shows a negative relationship with parity in NP ( P < .05). Conclusion: Reference range values of RV were generated for clinical use in our locality, while there is statistically significant difference between RV in NP and PIH women.


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