Anti-Invasive Activity of Bovine Lactoferrin against Listeria monocytogenes
1997 ◽
Vol 60
(3)
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pp. 267-271
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Keyword(s):
We have investigated the possible role of bovine lactoferrin in protecting the intestinal epithelium from bacterial infections, using as an in vitro model enterocyte-like cell lines HT-39 and Caco-2 infected with a food-borne pathogen, Listeria monocytogenes. When infection occurred in the presence of 1 mg/ml of bovine lactoferrin, in the form of apolactoferrin or iron- or manganese-saturated forms, the adhesion of bacteria to eukaryotk cells was unaffected, but the number of internalized bacteria was reduced by 42- to 125-fold. The possibility of a toxic effect of lactoferrin was excluded, because bovine lactoferrin was used at nonbactericidal and noncytotoxic concentrations.
2017 ◽
Vol 15
(4)
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pp. 255-264
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Keyword(s):
2019 ◽
Vol 289
◽
pp. 209-214
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Keyword(s):
2019 ◽
Vol 68
(1)
◽
pp. 358-368
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2010 ◽
Vol 188
(3)
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pp. 659-667
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Keyword(s):
Keyword(s):
Keyword(s):