Individual Therapy

2018 ◽  
pp. 31-136
Author(s):  
MISSING-VALUE MISSING-VALUE
Keyword(s):  
2020 ◽  
Vol 15 ◽  
Author(s):  
Jim Philip ◽  
Cornelius James Fernandez

: Meglitinides are a group of oral hypoglycemic medications currently approved for the treatment of type 2 diabetes mellitus (T2DM). Two meglitinide molecules, Repaglinide and Nateglinide,are presently in use. Repaglinide is preferred because of its superior glycemic efficacy.They have modest efficacy with a mean decrement of glycosylated haemoglobin (HbA1c) ranging between -0.2 to -1.50% with individual therapy. Additional HbA1c reduction can occur with combination therapy with other oral hypoglycemics. This class of drugs is effective in controlling postprandial hyperglycemia with minimal risk of hypoglycemia.It is also useful in patients in with variable meal timings, especially in the elderly, and in patients with renal failure. There are is a dearth of long-term studies on meglitinides to assess cardiovascular outcomes or mortality in T2DM,although the Nateglinide and Valsartan in Impaired Glucose ToleranceOutcomes Research (NAVIGATOR) study showed no difference between Nateglinide and placebo with regard to the core composite cardiovascular outcomes. Based on a PubMed literature search using key words: ‘meglitinides’, ‘repaglinide’, ‘nateglinide’, ‘HbA1c’, ‘glycated haemoglobin’, ‘cardiovascular safety’, ‘cardiovascular events’, ‘cardiovascular outcome trials’, ‘type 2 diabetes mellitus’ and heart failure, and combining the search terms using Boolean operators ‘AND’, ‘OR’ and ‘NOT’ as needed we compiled current evidence for use of these oral hypoglycemic agents in clinical use. This article is an attempt to review the efficacy and cardiovascular (CV) safety of Meglitinides to help clinicians to use this class of oral hypoglycaemic agents prudently.


Author(s):  
Alexander L. Chapman ◽  
Nora H. Hope

Developed to treat highly suicidal patients and often associated with the treatment of borderline personality disorder (BPD), dialectical behavior therapy (DBT) has evolved into a transdiagnostic treatment addressing emotion dysregulation. DBT is an emotion-focused, comprehensive cognitive-behavioral treatment including individual therapy, group skills training, between-session skills coaching (phone coaching), and a therapist consultation team. Several elements of DBT address emotion dysregulation directly or indirectly, including emotion regulation skills, distress tolerance strategies to dampen physiological arousal and curb impulses to engage in problematic behaviors, and individual therapy interventions to reduce emotion dysregulation. Growing evidence suggests that DBT may address behavioral, cognitive, physiological, and neurobiological aspects of emotion dysregulation. Future directions should include increasing multimethod research on the effects of DBT on emotion dysregulation, streamlining treatment, making DBT more efficient and targeted, and conceptualizing DBT’s place within the spectrum of other emotion-focused transdiagnostic treatments.


1988 ◽  
Vol 27 (2) ◽  
pp. 105-114 ◽  
Author(s):  
Susan P. Llewelyn ◽  
Robert Elliott ◽  
David A. Shapiro ◽  
Gillian Hardy ◽  
Jenny Firth-Cozens

2011 ◽  
Vol 21 (6) ◽  
pp. 709-721 ◽  
Author(s):  
Flavia Cigolla ◽  
Dora Brown
Keyword(s):  

1994 ◽  
Vol 79 (3_suppl) ◽  
pp. 1475-1478
Author(s):  
Atholl T. Malcolm ◽  
Michel Pierre Janisse

Three suicides occurred within 3 years in a military unit of 35 individuals. This represented an annual rate 220 times the North American average. A clinical intervention was requested by medical authorities, the goal being to minimize the risk of further deaths. Group and individual therapy was conducted over 3 days and ongoing referrals were made as necessary. In addition, measures of anxiety, depression, and hostility were obtained from this unit and from a unit equivalent in size and job description to examine whether these constructs could be used diagnostically. Analysis of the data indicated that differences in mean scores between the units yielded potentially misleading information, although on an individual basis scores were useful in identifying clients at risk of suicide. When those who personally knew one or more of the deceased were compared with those who did not, variability of scores in conjunction with interviews was helpful in identifying relatively high-risk subgroups.


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