Clinical presentation of depression in the elderly

Abstract Background Malignant otitis externa is a fatal infection of the external ear and temporal bone. Pseudomonas aeruginosa is the most common causative organism, while fungi are a rare cause of malignant otitis externa. We aimed to compare the clinical, therapeutic and evolutionary features between bacterial and fungal malignant otitis externa. Methods We conducted a retrospective study including all patients hospitalized for malignant otitis externa in the infectious diseases department between 2000 and 2018. Results Overall, we encountered 82 cases of malignant otitis externa, among which there were 54 cases (65.9%) of bacterial malignant otitis externa (BMO) and 28 cases (34.1%) of fungal malignant otitis externa (FMO). The males were predominant among BMO cases (57.4% vs 50%; p=0.5). Patients with FMO were significantly older (70±9 years vs 61±10 years; p< 0.001) and had medical history of diabetes mellitus more frequently (96.4% vs 77.8%; p=0.03). The use of topical corticosteroids was significantly more reported among FMO cases (28.6% vs 5.6%; p=0.006). Otalgia (96.4% vs 81.5%), otorrhea (75% vs 66.7%) and cephalalgia (46.4% vs 42.6%) were the revealing symptoms among FMO and BMO, respectively, with no significant difference. Tenderness to palpation of the mastoid bone (64.3% vs 38.9%; p=0.02) and stenosis of the external auditory canal (92.9% vs 72.2%; p=0.02) were significantly more frequent among FMO cases. Complications were significantly more frequent among FMO cases (42.9% vs 9.3%; p< 0.001). Treatment duration was significantly longer among FMO cases (70[40-90] days vs 45[34-75] days; p=0.03). Conclusion Our study showed that FMO affected more frequently the elderly and diabetic patients, when compared with BMO. Regardless of the causative agent, the clinical presentation was similar. However, the outcome was poor among FMO cases with the occurrence of complications, requiring a longer duration of treatment. Disclosures All Authors: No reported disclosures

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Clinical presentation, therapeutic approach, and outcome of young patients admitted for COVID-19, with respect to the elderly counterpart

Clinical and Experimental Medicine ◽

10.1007/s10238-021-00684-1 ◽

2021 ◽

Vol 21 (2) ◽

pp. 249-268

Author(s):

Martino Pepe ◽

Charbel Maroun-Eid ◽

Rodolfo Romero ◽

Ramón Arroyo-Espliguero ◽

Inmaculada Fernàndez-Rozas ◽

...

Keyword(s):

Therapeutic Approach ◽

Clinical Presentation ◽

Young Patients ◽

The Elderly

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Spontaneous resolution of large non-traumatic bilateral acute-on-chronic subdural hematoma

Romanian Neurosurgery ◽

10.1515/romneu-2017-0002 ◽

2017 ◽

Vol 31 (1) ◽

pp. 8-16

Author(s):

D. Adam ◽

D. Iftimie ◽

Gina Burduşa ◽

Cristiana Moisescu

Keyword(s):

Conservative Treatment ◽

Subdural Hematoma ◽

Clinical Presentation ◽

Surgical Intervention ◽

Chronic Subdural Hematoma ◽

The Elderly ◽

Neurological Status ◽

Spontaneous Resolution ◽

Subdural Hematomas ◽

Gcs Score

Abstract Background and importance: Chronic subdural hematomas are a frequently encountered neurosurgical pathology, especially in the elderly. They often require surgical evacuation, but recent studies have shown good results with conservative treatment in selected cases. Clinical presentation: We report the case of a 72-year old patient that developed large, non-traumatic, bilateral, acute-on-chronic subdural hematoma after repeated abdominal surgery for appendicular carcinoma. He presented an abdominal wound infection and good neurological status (GCS score of 14 points), factors that indicated the delay of surgical intervention. Subsequent clinical and radiological improvement forestalled the operation altogether and he presented complete spontaneous resolution of subdural hematomas at only 5 months after diagnosis. Conclusion: Although surgical treatment is performed in the majority of chronic subdural hematomas, in clinically and radiologically selected cases, the operation can be avoided. The hematoma can present resolution, either spontaneously or with the help of conservative treatment.

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Clinical manifestations of chronic subdural hematoma in the elderly: Literature Review

10.5327/1516-3180.462 ◽

2021 ◽

Author(s):

Gabriela Ferreira Kalkmann ◽

Carlos Umberto Pereira ◽

Francisco de Assis Pereira ◽

Débora Moura da Paixão Oliveira ◽

Nicollas Nunes Rabelo

Keyword(s):

Early Diagnosis ◽

Literature Review ◽

Subdural Hematoma ◽

Elderly Population ◽

Clinical Presentation ◽

Clinical Manifestations ◽

Chronic Subdural Hematoma ◽

Signs And Symptoms ◽

The Elderly ◽

Study Results

Introduction: The clinical manifestations of chronic subdural hematoma (CSDH) are often confused with other medical entities in the elderly, making their early diagnosis difficult or difficult. Early diagnosis is important, since its prognosis is directly associated with the preoperative neurological state, thus resulting in a worse vital and functional prognosis. Objectives: Report through a literature review the clinical manifestations of CSDH in the elderly population. Methods: Literature review, with the search terms: “Signs and Symptoms”, “Chronic Subdural Hematoma”, Aged, Diagnosis and Prognosis. In which PubMed, Lilacs, Scielo, Cochrane and TripDataBase data platforms were used. The inclusion criteria were: original studies published in any language. Articles in which full reading was prevented were excluded. With the application of the inclusion and exclusion criteria, 110 articles were included in the study. Results: Clinical presentation depends on the location, volume of the hematoma, rapid growth, the location of the CSDH, whether unilateral or bilateral, and the clinical conditions of the patient. Because the forms of clinical presentation of CSDH are variable, it is necessary that health professionals linked to the elderly (geriatrician, psychiatrist, general practitioner) have knowledge of this clinical entity. Conclusions: The recognition of classic forms as well as the identification of risk factors in the elderly favors the timely diagnosis and treatment of CSDH in the elderly population.

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Meningitis, Clinical Presentation of Tetanus

Case Reports in Infectious Diseases ◽

10.1155/2015/372375 ◽

2015 ◽

Vol 2015 ◽

pp. 1-2 ◽

Cited By ~ 2

Author(s):

Anna Moniuszko ◽

Agata Zajkowska ◽

Ewa Tumiel ◽

Krzysztof Rutkowski ◽

Piotr Czupryna ◽

...

Keyword(s):

Intensive Care Unit ◽

Differential Diagnosis ◽

Clinical Presentation ◽

The Elderly ◽

Developed Countries ◽

Fatal Disease ◽

Clostridium Tetani ◽

Foot Injury ◽

Sporadic Cases ◽

Tetanus Immunization

Background. Tetanus is an acute disease caused by a neurotoxin produced byClostridium tetani. Tetanus immunization has been available since the late 1930s but sporadic cases still occur, usually in incompletely vaccinated or unvaccinated individuals.Case Report. An elderly previously vaccinated female contracted tetanus following foot injury. Clinically she presented with meningitis causing diagnostic and therapeutic delays.Why Should Physician Be Aware of This?Even in developed countries the differential diagnosis of meningitis, especially in the elderly, should include tetanus. Treatment in intensive care unit is required. General population might benefit from vaccine boosters and education on this potentially fatal disease.

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A peculiar uncommon cutaneous neoplasia: Angiosarcoma of the head and neck of the elderly (Wilson Jones Angiosarcoma)

Case Reports in Clinical Pathology ◽

10.5430/crcp.v6n1p9 ◽

2019 ◽

Vol 6 (1) ◽

pp. 9

Author(s):

Alessandro D'Amuri ◽

Federica Floccari ◽

Raffaele Filotico ◽

Marcello Filotico

Keyword(s):

Head And Neck ◽

Clinical Presentation ◽

Morphological Characteristics ◽

The Elderly ◽

Classic Case

Cutaneous Angiosarcoma of the elderly's face is a rare and peculiar neoplasm with all its own clinical and morphological characteristics. The observation of a classic case in the clinical presentation and morphology has offered the opportunity to revisit this topic.

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Manic syndromes in old age

10.1093/med/9780199644957.003.0044 ◽

2013 ◽

Cited By ~ 1

Author(s):

Akshya Vasudev

Keyword(s):

Bipolar Disorder ◽

Clinical Presentation ◽

Age Of Onset ◽

Late Onset ◽

Epidemiological Data ◽

The Elderly ◽

Published Data ◽

Management Options ◽

Pharmacological Management ◽

Heterogenous Group

Manic syndromes in the elderly are different from those seen in the younger bipolar population. They are a heterogenous group but can probably be divided into two main groups based on age of onset of the illness: late onset bipolar disorder (LOB) and early onset bipolar disorder (EOB). This chapter elaborates on differences in these two groups based on epidemiological data findings, clinical presentation, aetiopathogenesis and management. Latest concepts with regards to the vascular mania hypothesis, neuroimaging findings, cognitive impairment in bipolar disorder are also dealt with. A critical review of pharmacological management options is also provided with reference to recently published data on mood stabilisers, antipsychotic and antidepressant usage for this age group.

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Clinical Presentation of Peptic Ulcer in the Elderly

Gerontology ◽

10.1159/000213864 ◽

1997 ◽

Vol 43 (5) ◽

pp. 283-288 ◽

Cited By ~ 32

Author(s):

H. Kemppainen ◽

I. Räihä ◽

L. Sourander

Keyword(s):

Peptic Ulcer ◽

Clinical Presentation ◽

The Elderly

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Update on Amyloid-associated Intracerebral Haemorrhage

European Neurological Review ◽

10.17925/enr.2012.07.01.22 ◽

2012 ◽

Vol 7 (1) ◽

pp. 22 ◽

Cited By ~ 3

Author(s):

Rebbeca Grysiewicz ◽

Philip B Gorelick ◽

◽

Keyword(s):

Intracerebral Haemorrhage ◽

Scientific Inquiry ◽

Clinical Presentation ◽

The Elderly ◽

Superficial Siderosis ◽

Amyloid Angiopathy ◽

Common Cause ◽

Prevention And Treatment ◽

Primary Focus ◽

Brain Haemorrhage

Cerebral congophilic or amyloid angiopathy (CAA) is a clinicopathological entity that is considered a common cause of primary non-traumatic brain haemorrhage in the elderly. CAA is frequently associated with Alzheimer’s disease (AD) and has become a primary focus of scientific inquiry. The spectrum of intracerebral haemorrhage (ICH) that may occur in CAA includes: cerebral lobar haemorrhages, deep haemorrhages, purely subarachnoid and subdural haemorrhages and cerebral microbleeds. CAA is also associated with microinfarcts, leukoencephalopathy and superficial siderosis. This brief article will provide an update on the advances in our understanding of CAA-associated ICH with a focus on the following topics: neuropathology and mechanism of CAA-related haemorrhage; epidemiology, including genetic and other possible risk factors; clinical presentation; diagnosis, including newer imaging modalities; and prospects for prevention and treatment.

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