scholarly journals Hubungan antara Kadar Low Density Lipoprotein dengan Tekanan Darah Sistolik saat Puncak Exercise pada Personil Kepolisian Daerah Sulawesi Tenggara (The Relationship between Low Density Lipoprotein Levels and Systolic Blood Pressure during Peak Exercise of Police Personnel in Southeast Sulawesi)

MEDULA ◽  
2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Dina Fitriana ◽  
Hilma Yuniar ◽  
Jamaluddin Jamaluddin
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Peak Exercise ◽  
P Value ◽  
Low Density ◽  
Cross Sectional ◽  
Police Personnel ◽  
The Relationship

Background: Systolic blood pressure during exercise is the blood pressure as measured by aneroid sphygmomanometer at the peak exercise (treadmill), namely when the subject has experienced fatigue or heart rate has reached > 85% of Maximum Heart Rate. Purpose:This research purpose is to determine the relationship between LDL level and systolic blood pressure at the exercise peak of  police personnel in Southeast Sulawesi. Methods: This research used analytical-observasional study with cross sectional aproach. The independent variables used in this research are LDL level while the dependent variables was systolic blood pressure during the peak exercise. Research location is in Maxima Laboratory Kendari.The subjects of this study were 95 people based on the inclusion and exclusion criteria that selected by Purposive Sampling method. Data collection was gained by taking the secondary data and was processed by using statistical test data of Independent T-test with a significance p-value <0.05. Result: The result of bivariate analysis showed that there was a relationship between LDL level and systolic blood pressure at the exercise peak on the police personnel in Southeast Sulawesi with a p-value = 0,000 (<0.05). Conclusion: This study can be conlcuded that there was a relationship between LDL level and systolic blood pressure at the peak exercise of police personnel in Southeast Sulawesi.Keywords: low density lipoprotein, systolic blood pressure, peak exercise. ABSTRAKLatar belakang : Puncak tekanan darah sistolik pada saat exercise adalah tekanan darah sistolik yang diukur dengan menggunakan sfignomanometer air raksa pada saat puncak exercise, dimana subyek sudah mengalami kelelahan atau denyut jantung telah mencapai 85% dari denyut jantung maximal. Tujuan: Tujuan penelitian ini adalah untuk mengetahui hubungan antara kadar LDL plasma dengan tekanan darah sistolik pada puncak exercise pada personil Kepolisian Daerah Sulawesi Tenggara. Metode: penelitian ini merupakan penelitian analitik-observasional dengan metode cross sectional. variabel independen adalah kadar LDL plasma dan dependen variabel adalah tekanan darah sistol pada puncak exercise. penelitian dilakukan di Laboratorium Klinik Maxima Kendari. sebanyak 95 sampel penelitian yang memenuhi kriteria inklusi dan eksklusi diambil dengan metode purposive sampling. Data tekanan darah saat puncak exercise dan kadar LDL plasma diambil dari data sekunder rekam medik pasien. Data kemudian dianalisa dengan uji statistik Independent T-test dan bermakna bila nilai p <0,05. Hasil: Analisa statistik menunjukkan adanya hubungan antara kadar LDL plasma dengan tekanan darah sistolik pada puncak exercise pada personil POLDA Sulawesi Tenggara, dengan nilai p=0,000. Simpulan : Pada penelitian ini dapat disimpulkan bahwa terdapat hubungan antara kadar LDL plasma dengan tekanan darah sistolik pada puncak exercise pada personil POLDA Sulawesi Tenggara.Kata Kunci: low density lipoprotein, tekanan darah sistolik, puncak exercise

Jumpstarting Health With a 15-Day Whole-Food Plant-Based Program

2021 ◽  
pp. 155982762110063
Author(s):  
Susan M. Friedman ◽  
Carol Hee Barnett ◽  
Robert Franki ◽  
Bruce Pollock ◽  
Beth Garver ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Blood Sugar ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Food Plant ◽  
Fasting Blood Sugar ◽  
Average Weight ◽  
Low Density ◽  
Average Drop

The 15-day Jumpstart was developed as an evidence-based, affordable, standardized, replicable, and scalable program, designed to demonstrate quickly to patients that changing what they eat can improve their health. The program was designed using the principles of the self-determination theory of motivation and personality. Patients were instructed to eat an Esselstyn-compliant, whole-food plant-based diet consisting of vegetables, fruits, whole grains, and legumes. Of the 389 participants in the program from September 2018 to February 2020, average weight loss was 5.8 pounds (7.3 for those whose body mass index was >30), average systolic blood pressure drop was 6.8 points (16.8 points for those with systolic blood pressure >140), average drop in cholesterol was 26 points (44 points for those with a cholesterol >200), average drop in low-density lipoprotein was 19 points (33 points for those with a low-density lipoprotein >100), and average drop in fasting blood sugar was 5.1 points (28.4 points for those starting in the diabetic range); P value was <.005 for fasting blood sugar and <.001 for all other comparisons. A 15-day program that helps patients adopt an Esselstyn-style whole-food plant-based diet, through education, individualized medical feedback, social support, and facilitated small group work, rapidly improves health.

scholarly journals Cardiometabolic risk factors are associated with immune cell mitochondrial respiration in humans

2020 ◽  
Vol 319 (2) ◽  
pp. H481-H487
Author(s):  
Theodore M. DeConne ◽  
Eric R. Muñoz ◽  
Faria Sanjana ◽  
Joshua C. Hobson ◽  
Christopher R. Martens
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Mitochondrial Respiration ◽  
Cardiometabolic Risk ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol

Independent of other cardiometabolic risk factors, low-density lipoprotein cholesterol, and systolic blood pressure were found to be negatively associated with several parameters of mitochondrial respiration in peripheral blood mononuclear cells of healthy adults. These data suggest that low-density lipoprotein cholesterol and systolic blood pressure may induce metabolic reprogramming of immune cells, contributing to increased cardiovascular disease risk and impaired immune health.

scholarly journals Anti-atherosclerotic effects of konjac

2015 ◽  
Vol 5 (4) ◽  
pp. 136
Author(s):  
Hidekatsu Yanai ◽  
Hiroki Adachi ◽  
Hisayuki Katsuyama ◽  
Hidetaka Hamasaki ◽  
Akahito Sako
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Glucose Metabolism ◽  
Dietary Fiber ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Future Studies ◽  
The Relationship

Definition: The Konjac plant comes from the genus Amorphophallus. Japanese food uses Konjac cake. Konjac contains almost no calories and a great amount of dietary fiber. Here, we reviewed possible anti-atherosclerotic effects of konjac, using the search Pubmed ®. Konjac ingestion is likely beneficially associated with obesity, blood pressure, lipid and glucose metabolism. However, evidence is lacking on the relationship between konjac ingestion and development of atherosclerotic diseases. To more fully understand the anti-atherosclerotic effects of konjac, future studies, preferably with larger numbers of subjects, will be performed.Keywords: atherosclerosis, body weight, glucose, konjac mannan, low-density lipoprotein-cholesterol

scholarly journals Glycaemic, blood pressure and low-density lipoprotein-cholesterol control among patients with diabetes mellitus in a specialised clinic in Botswana: a cross-sectional study

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e026807 ◽  
Author(s):  
Julius Chacha Mwita ◽  
Joel M Francis ◽  
Bernard Omech ◽  
Elizabeth Botsile ◽  
Aderonke Oyewo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Low Density ◽  
Sectional Study ◽  
Low Density Lipoprotein Cholesterol ◽  
Cross Sectional ◽  
Patients With Diabetes

ObjectiveControl of glycaemic, hypertension and low-density lipoprotein-cholesterol (LDL-C) among patients with type 2 diabetes mellitus (T2DM) is vital for the prevention of cardiovascular diseases. The current study was an audit of glycaemic, hypertension and LDL-C control among ambulant patients with T2DM in Botswana. Also, the study aimed at assessing factors associated with attaining optimal glycaemic, hypertension and LDL-C therapeutic goals.DesignA cross-sectional study.SettingA specialised public diabetes clinic in Gaborone, Botswana.ParticipantsPatients with T2DM who had attended the clinic for ≥3 months between August 2017 and February 2018.Primary outcome measureThe proportion of patients with optimal glycaemic (HbA1c<7%), hypertension (blood pressure <140/90 mm Hg) and LDL-C (<1.8 mmol/L) control.ResultsThe proportions of patients meeting optimal targets were 32.3% for glycaemic, 54.2% for hypertension and 20.4% for LDL-C. Age≥ 50 years was positively associated with optimal glycaemic control (adjusted OR [AOR] 5.79; 95% CI 1.08 to 31.14). On the other hand, an increase in diabetes duration was inversely associated with optimal glycemic control (AOR 0.91; 95% CI 0.85 to 0.98). Being on an ACE inhibitor was inversely associated with optimal hypertension control (AOR 0.35; 95% CI 0.14 to 0.85). Being female was inversely associated with optimal LDL-C control (AOR 0.24; 95% CI (0.09 - 0.59).ConclusionPatients with T2DM in Gaborone, Botswana, presented with suboptimal control of recommended glycaemic, hypertension and LDL-C targets. These findings call for urgent individual and health systems interventions to address key determinants of the recommended therapeutic targets among patients with diabetes in this setting.

scholarly journals Assessment of Small Dense Low-Density Lipoprotein and Apolipoprotein B/Apolipoprotein A-I Ratio to Predict the Peripheral Arterial Disease in Patients with Hypertension

2020 ◽  
Vol 26 (3) ◽  
Author(s):  
Kurniawan Prihutomo ◽  
MID. Pramudianti ◽  
Amiroh Kurniati
Keyword(s):  
Peripheral Arterial Disease ◽  
Low Density Lipoprotein ◽  
Multivariate Logistic Regression Analysis ◽  
Density Lipoprotein ◽  
Arterial Disease ◽  
Bivariate Analysis ◽  
P Value ◽  
Low Density ◽  
Cross Sectional ◽  
Peripheral Arterial

Small Dense Low-Density Lipoprotein (sdLDL) and the ApoB/ApoA-I ratio has greater atherogenic potential and is a better marker to predict atherosclerotic blood vessel disease. The purpose of this study was to determine the relationship between the sdLDL and ApoB/ApoA-I ratio to assess the prevalence risk of Peripheral Arterial Disease (PAD) in hypertensive patients. A cross-sectional observational analytic study was performed in 51 hypertension patients with age> 18 years old in Dr. Moewardi Hospital Surakarta from May until June 2018. Patients have measured ABI scores, BMI, blood pressure, lipid profile, ApoB, and ApoA levels. Data were statistically analyzed was using bivariate analysis and multivariate analysis. P-value <0.05 was statistically significant. The prevalence of PAD was 54.90%. Bivariate analysis of age variables (PR: 3.15; 95%Cl: 1.128-8.811; p=0.005), sdLDL (PR: 2; 95%Cl: 0.997-4.013; p=0.03), the ratio of ApoB/ApoA-I (PR: 5.786; 95%Cl: 0.899-37.224; p=0.007), and smoking (PR: 1.896; 95%Cl: 1.210-2.971; p=0.015) was significantly related with PAD. After adjustment of age, smoking, and dyslipidemia variables using multivariate logistic regression analysis, PAD was still related with sdLDL (PR: 10.55; 95%CI: 1.80-61.73; p=0.009), age (PR: 11. 61; 95%CI: 1.83-61.73; p=0.009), and smoking (PR: 11.96; 95%CI: 1.71-83.81; p= 0.013). sdLDL and ApoB/ApoA-I ratio were related to PAD. However, sdLDL, age, and smoking are independent variables of PAD in hypertension patients.

scholarly journals Associations of serum low-density lipoprotein and systolic blood pressure levels with type 2 diabetic patients with and without peripheral neuropathy: Systemic review, meta-analysis and meta-regression analysis of observational studies

2019 ◽  
Author(s):  
Syed Shah Zaman Haider Naqvi ◽  
Saber imani ◽  
Hossein Hosseinifard ◽  
QingLian Wen ◽  
M. Naveed Shahzad ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Peripheral Neuropathy ◽  
Systolic Blood Pressure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Systemic Review ◽  
Low Density ◽  
Collision Risk ◽  
Meta Regression

Abstract Background: Compositional abnormalities in lipoproteins and cardiovascular risk factors play an important role in the progression of diabetic peripheral neuropathy (DPN). This systematic review aimed to estimate the predicting value of low-density lipoprotein (LDL) and systolic blood pressure (SBP) level in type-2 diabetes mellitus (T2DM) patients with and without peripheral neuropathy. We also tried to determine whether LDL and SBP are associated with an increased collision risk of DPN. Materials: A systematic search was conducted for eligible publications which explored the LDL and SBP level in T2DM patients with and without peripheral neuropathy. The quality of the included studies was assessed by the QUADAS-2 tool. The standardized mean difference (SMD) with 95% CI of LDL and SBP level were pooled to assess the correlation between LDL and SBP level with DPN. We performed random effects meta-regression analyses to investigate factors associated with an increased collision risk of DPN. Results: There was a significant association between LDL and SBP with poor prognosis of DPN in those included studies (I 2 = 88.1% and I 2 = 84.9%, respectively, Both P < 0.001 ). European T2DM patients have higher serum level of LDL in compare with the European DPN patients (SMD = 0.16, 95 % CI: -0.06 - 0.38; P < 0.001). SBP level was associated with a 2.6-fold decrease in non-DPN patients of T2DM (SMD = -2.63, 95% CI: -4.00 - -1.27, P < 0.001). Old age European T2DM patients have significantly high risk for diabetes drivers. Furthermore, the results of the case-control study design model are more precise to show the accuracy of SBP in Asian T2DM patients. Conclusion: Our finding supports the LDL and SBP status could be associated with increased risk of peripheral neuropathy in T2DM patients.

scholarly journals Associations of serum low-density lipoprotein and systolic blood pressure levels with type 2 diabetic patients with and without peripheral neuropathy: Systemic review, meta-analysis and meta-regression analysis of observational studies

2019 ◽  
Author(s):  
Syed Shah Zaman Haider Naqvi ◽  
Saber imani(Former Corresponding Author) ◽  
Hossein Hosseinifard ◽  
QingLian Wen ◽  
M. Naveed Shahzad ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Peripheral Neuropathy ◽  
Systolic Blood Pressure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Systemic Review ◽  
Low Density ◽  
Collision Risk ◽  
Meta Regression

Abstract Background:Compositional abnormalities in lipoproteins and cardiovascular risk factors play an important role in the progression of diabetic peripheral neuropathy (DPN). This systematic review aimed to estimate the predicting value of low-density lipoprotein (LDL) and systolic blood pressure (SBP) level in type-2 diabetes mellitus (T2DM) patients with and without peripheral neuropathy. We also tried to determine whether LDL and SBP are associated with an increased collision risk of DPN. Materials and Methods:A systematic search was conducted for eligible publications which explored the LDL and SBP level in T2DM patients with and without peripheral neuropathy. The quality of the included studies was assessed by the QUADAS-2 tool. The standardized mean difference (SMD) with 95% CI of LDL and SBP level were pooled to assess the correlation between LDL and SBP level with DPN. We performed random effects meta-regression analyses to investigate factors associated with an increased collision risk of DPN. Results:There was a significant association between LDL and SBP with poor prognosis of DPN in those included studies (I2= 88.1% and I2= 84.9%, respectively, Both P < 0.001). European T2DM patients have higher serum level of LDL in compare with the European DPN patients (SMD = 0.16, 95 % CI: -0.06 - 0.38; P <0.001). SBP level was associated with a 2.6-fold decrease in non-DPN patients of T2DM (SMD = -2.63, 95% CI: -4.00 - -1.27, P <0.001). Old age European T2DM patients have significantly high risk for diabetes drivers. Furthermore, the results of the case-control study design model are more precise to show the accuracy of SBP in Asian T2DM patients. Conclusion:Our finding supports the LDL and SBP status could be associated with increased risk of peripheral neuropathy in T2DM patients.

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