scholarly journals EVALUATION OF EFFICACY OF DARUHARIDRA CHANDANA MALAHARA LEPA AND PANCHAVALKALA MALAHARA LEPA IN PARIKARTIKA WITH SPECIAL REFERENCE TO ACUTE FISSURE IN ANO

2021 ◽  
Vol 9 (8) ◽  
pp. 1623-1628
Author(s):  
Suresh Y. Bhajantri ◽  
Gannur P. G. ◽  
Gujar R. S.
Keyword(s):  
Quality Of Life ◽  
Anal Canal ◽  
Special Reference ◽  
Clinical Condition ◽  
Signs And Symptoms ◽  
Burning Sensation ◽  
Fissure In Ano ◽  
Men And Women ◽  
Anal Region

Background: Parikartika (Fissure-in-ano) is a clinical condition enrolled with the Laxana’s like Kartanavat (cut- ting type of pain) and Chedanavat Shoola in the anal region and it can be correlated with Anal Fissure associated with Pain, Burning sensation during Defecation and tear in the distal Anal Canal. The Incidence rate of Anal Fis- sure is around 1 in 350 adults they occur equally common in men and women and most often occurs in adults aged 15 to 40. Aims and Objectives: To compare the Efficacy of Daruharidra Chandana Malahara with Pan- chavalkala Malahara in the Management of Parikartika (Acute fissure in ano). Materials and Methods: For the Present study, cases were selected from OPD and IPD of Shalya Tantra with the Classical Clinical Features like Kartanvat and Chedanavat Shoola in the anal region. Intervention: Daruharidra Chandana Malahara Lepa and Panchavalkala Malahara Lepa, applied Locally into Two Groups with each Group having 20 Patients for 7 days along with Triphala Choorna (1tsp) HS. Results: Copesetic Relief was seen in Signs and Symptoms and Im- proved Quality of Life after Treatment. Conclusion: The Study Was Proved that Parikartika was Effectively Managed by Daruharidra Chandana Malahara Lepa comparatively Panchavalkala Malahara Lepa. Keywords: Parikartika, Fissure-in-ano, Daruharidra Chandana Malaharal Lepa, Panchavalkala Malahara Le- pa.

scholarly journals PRELIMINARY CLINICAL STUDY TO EVALUATE JATYADI GHRITA SUPPOSITORY IN THE MANAGEMENT OF PARIKARTIKA WITH SPECIAL REFERENCE TO FISSURE-IN-ANO.

2019 ◽  
Vol 7 (4) ◽  
Author(s):  
Ashwini Bhikaji Rathod
Keyword(s):  
Clinical Study ◽  
Anal Canal ◽  
Signs And Symptoms ◽  
Burning Sensation ◽  
Point Of View ◽  
Anal Margin ◽  
Sleep Habits ◽  
Fissure In Ano ◽  
Fast Foods ◽  
Bowel Movements

The earliest reference of Parikartika was available in Acharya Charaka, Sushruta and Kashyap Samhita. In modern point of view, it can be correlated with Fissure-In-Ano. Now a day, in Modern technological era, due to changing life style, consumption of fast foods, improper sleep habits may ultimately results into irregular bowel movements and constipation leads to the passage of hard stool and finally it causes erosion and deep tear through the skin of the anal margin extending into anal canal, which named as Parikartika i.e. Fissure-In-Ano. In this study total 10 patients of Parikartika having signs and symptoms of same, selected from Arogyashala Rugnalaya OPD of Shalyatantra Department. The patients were treated with self-made “Jatyadi Ghrita Suppository” per anus for 10 days daily. Assessment was done on the basis of criteria such as burning sensation, pain, spasm, and itching. The better result was observed in reduction of burning sensation, pain, spasm and itching after treatment. Key words: Parikartika, Jatyadi Ghrita, Suppository, Fissure-In-Ano

Efficacy and safety of beta-blockers and prolonged bronchodilators in patients with heart failure with coronary artery disease and moderate to severe COPD

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
V Evdokimov ◽  
E Yushchuk ◽  
A Evdokimova ◽  
S Ivanova ◽  
I Sadulaeva
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Clinical Condition ◽  
Blood Pressure Monitoring ◽  
Beta Blockers ◽  
Control Group ◽  
Efficacy And Safety ◽  
Serious Adverse Events ◽  
Severe Copd

Abstract Purpose To compare clinical efficacy and safety of various treatment regimens with the inclusion of beta-blockers, RAAS antagonists (ACE inhibitors or ARBs), prolonged bronchodilators (LABA, LAMA) in heart failure patients with CAD and COPD. Methods 385 patients (292 men and 93 women), aged 66.3±4.1 years, with CHF classes II to III (NYHA) combined with moderate to severe COPD (GOLD) and with LVEF less than 45% were randomized into nine groups: enalapril + LAMA (control group), nebivolol + enalapril + LAMA, nebivolol + losartan + LAMA, nebivolol + losartan + LABA, nebivolol + losartan + LAMA/LABA, carvedilol + enalapril + LAMA, carvedilol + losartan + LAMA, carvedilol + losartan + LABA, carvedilol + losartan + LAMA/LABA. Patients of all groups received complex CHF treatment comprising diuretics, nitrates, cardiac glycosides (if necessary). Clinical examination, TTE, 6-minute walk test (6MWT), 24-hour electrocardiogram and blood pressure monitoring, respiratory function test were assessed at baseline and after 6 months of treatment. The quality of life was evaluated by MYHFQ, SGRQ and mMRC scale. Results After 6 months of therapy the improvement of clinical condition and quality of life were marked in all groups. At the end of observation period there was a significant improvement of patients clinical condition, quality of life, reduction of mean CHF FC and dyspnea severity, increase of exercise tolerance, slowing of progression of CHF and COPD, improvement of the parameters of intracardiac hemodynamics, structural and functional parameters of the left and right heart (a decrease in the size of the atria, LV volumes and internal dimension at end-diastole and end-systole, cardiac index, LVMMI, an increase of LVEF, a significant decrease in systemic vascular resistance and the pulmonary hypertension grade, significant improvement in systolic and diastolic function of the ventricles, regression of pathological remodeling of the heart, reduction of heart rate, duration and frequency of myocardial ischemia episodes (including its “silent” form). The best results were obtained in groups using a beta-blocker (nebivolol or carvedilol), a RAAS antagonist, and a combination of long-acting bronchodilators (indacaterol and tiotropium) – group 5 and 9. It is worth noting that beta-blockers, LABA and LAMA were well tolerated in all observation groups and serious adverse events were absent. Conclusions The appointment of 3-generation beta-blockers to patients with CHF on the background of CAD and COPD can significantly increase the effectiveness of treatment and does not cause a deterioration in spirometry in patients with such cardiopulmonary pathology. In our opinion, the most important point in the appointment of beta blockers to patients with moderate to severe COPD is low start dose and slow titration of the dose at the beginning of the therapy. It is advisable to include in the complex therapy of such patients a combination of LABA and LAMA as a basic bronchodilator support. Funding Acknowledgement Type of funding source: None

Quality of life in terminal care—with special reference to age, gender and marital status

2005 ◽  
Vol 14 (4) ◽  
pp. 320-328 ◽  
Author(s):  
C. Lundh Hagelin ◽  
Åke Seiger ◽  
C. J. Fürst
Keyword(s):  
Quality Of Life ◽  
Marital Status ◽  
Special Reference ◽  
Terminal Care

Exercise-Induced Scalenus Syndrome

2008 ◽  
Vol 36 (2) ◽  
pp. 369-374 ◽  
Author(s):  
Panagiotis Baltopoulos ◽  
Charalampos Tsintzos ◽  
George Prionas ◽  
Maria Tsironi
Keyword(s):  
Quality Of Life ◽  
Thoracic Outlet Syndrome ◽  
Surgical Intervention ◽  
Case Series ◽  
Signs And Symptoms ◽  
Underlying Mechanism ◽  
Level Of Evidence ◽  
Full Activity ◽  
Exercise Induced

Background Thoracic outlet syndrome is described as a group of distinct disorders producing signs and symptoms attributed to compression of nerves and blood vessels in the thoracic outlet region. Purpose To describe the exercise-induced scalenus anticus syndrome attributed to the anterior scalenus hypertrophy as a thoracic outlet syndrome underlying mechanism and to give recommendations for a safe and effective surgical treatment. Study Design Case series; Level of evidence, 4. Methods Twelve young professional athletes admitted for thoracic outlet syndrome (8 cases of neurologic thoracic outlet syndrome, 4 cases of mixed neurologic and vascular thoracic outlet syndrome) who reported numbness, tingling, early fatigue, muscle weakness, and pain were enrolled in the study. Scalenus hypertrophy was suspected to be the causative factor. Scalenectomy was performed in all cases. Results All patients had moderate to severe hypertrophy of the anterior scalenus muscle. Scalenectomy was performed, and there were no intraoperative or postoperative complications. Full activity was quickly achieved, and no recurrence of symptoms was documented. Conclusion Surgical intervention for scalenus anticus syndrome can allow an athlete to return to full activity and improve quality of life. Surgical intervention seems to be the treatment of choice in terms of restoring quality of life and physical activity.

scholarly journals Comparison of quality of life between men and women who underwent Transforaminal Percutaneous Endoscopic Discectomy for lumbar disc herniation

10.14444/4028 ◽  
2017 ◽  
Vol 11 (4) ◽  
pp. 28 ◽  
Author(s):  
Stylianos Kapetanakis ◽  
Grigorios Gkasdaris ◽  
Tryfon Thomaidis ◽  
Georgios Charitoudis ◽  
Konstantinos Kazakos
Keyword(s):  
Quality Of Life ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Men And Women ◽  
Endoscopic Discectomy

scholarly journals Dr the efficacy of karpoor ghrith in the management of parikartika.

2020 ◽  
Vol 8 (05) ◽  
Author(s):  
Om Dhote
Keyword(s):  
Surgical Treatment ◽  
Anal Canal ◽  
Faecal Incontinence ◽  
Squamous Epithelium ◽  
Burning Sensation ◽  
Local Application ◽  
Ancient Text ◽  
Fissure In Ano ◽  
Longitudinal Ulcer ◽  
Stratified Squamous Epithelium

Fissure in Ano ( Parikartika) is a vertical tear or an elongated longitudinal ulcer in the long axis of stratified squamous epithelium of the lower anal canal. Ancient text couldn’t give a brief idea about this condition. Mainly it has been described as complication of Bastikarma and Atisar. It is so named in which sharp cutting pain is felt in the anus. For that Modern surgical treatment of choice is again has limitations such as faecal incontinence. Hence, karpoor Ghrita having effective Vranaropan & vedanashamak, tridoshaghna  property i.e. it relieves burning sensation quickly. So we modified a method of Local Application is conceived for this study.   

scholarly journals Quality of Life and Depressive Signs and Symptoms of the Elderly Women with Breast Cancer

10.3823/2055 ◽  
2016 ◽  
Author(s):  
Nathacha Adriela Lima de Carvalho ◽  
Maria do Livramento Fortes Figueiredo ◽  
Chrystiany Plácido de Brito Vieira ◽  
Jaqueline Carvalho e Silva Sales ◽  
Maria Helena Barros Araújo Luz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Elderly Women ◽  
Signs And Symptoms ◽  
The Elderly
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