scholarly journals NEW DOSAGE FORM IN AYURVEDA - THERMO-SENSITIVE VAGINAL GEL OF PVK EXTRACT

2021 ◽  
Vol 9 (8) ◽  
pp. 1754-1758
Author(s):  
Kirtidhara Behera ◽  
Usha Sharma ◽  
Shuchi Mitra ◽  
Khem Chand Sharma
Keyword(s):  
Room Temperature ◽  
Dosage Forms ◽  
Cellulose Derivatives ◽  
Liquid Form ◽  
Ancient Medicine ◽  
Thermosensitive Gel ◽  
Vaginal Gel ◽  
Poly Ethylene Oxide ◽  
Ancient Times ◽  
Poly Ethylene

Rasashastra & Bhaisajya Kalpana is the prime branch of Ayurveda because of the preparation of medicine described in this branch. In ancient times pharmacokinetics of the drug was described in the principle of Dosha and Dushya which is a comprehensive matter for Ayurvedic professionals. But for global acceptance, we need to describe this view (pharmacokinetics) in the form of pharmacological language and convert this ancient medicine in the form of new dosage forms like gel, granules, syrup etc. Panchavalkal Kashaya was described for the treatment of women disease wounds and ulcers in different Ayurvedic texts like Charaka Samhita, Sharangdhara Samhita, Kashyapa Samhita, Bharat Bhaisajya Ratnakar, Bhava-Prakash. In this article, an attempt has been made to describe how to prepare the thermo-sensitive vaginal gel form, of Panchavalkal Kashaya extract for the use of women diseases like leucorrhoea. The thermosensitive gel is in the liquid form at room temperature (20- 25°C) and undergoes gelation when in contact with body fluid (35-37°C). There are many thermo-sensitive polymers like cellulose derivatives, poloxamer, poly (ethylene oxide) /poly (D, L- lactic acid-glycolic acid). Keywords: Ayurveda, Panchvalkal Kashaya, Thermo-sensitive gel, Charaka Samhita.

Li ion Conduction in Cross-Linked Peo-LiCF3SO3 Complex

1988 ◽  
Vol 135 ◽  
Author(s):  
Jun Tsuchiya
Keyword(s):  
Diffusion Coefficient ◽  
Room Temperature ◽  
Transport Number ◽  
Diffusion Measurement ◽  
Poly Ethylene Oxide ◽  
Li Ion ◽  
Poly Ethylene ◽  
Pfg Nmr ◽  
And Diffusion ◽  
Ion Transport Number

AbstractIonic migration of cross-linked amorphous Poly (Ethylene Oxide)-LiCF3SO3was investigated by measuring ionic conductivity and diffusion coefficient. Pulsed-Field-Gradient NMR (PFG-NMR) was used for the diffusion measurement. The measurements were carried out at a temperature region between room temperature and 120°C. The PFG-NMR mea-surement shows the two modes of migration of both cation(Li) and anion (CF3 SO3-) for specimens containing plasticizer (CH30(CHeiH20)gH3C). The two modes of migration for anion are present for specimens without the plasticizer. Li+ transport number is found to be less than 0.1 for specimens without the plasticizer. Plasticizer is found to increase the Li+ ion transport number.

scholarly journals Preparation, Properties and Cell Biocompatibility of Room Temperature LCST-Hydrogels Based on Thermoresponsive PEO Stars

Gels ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. 84
Author(s):  
Bagus Santoso ◽  
Paul Turner ◽  
Lyall Hanton ◽  
Stephen C. Moratti
Keyword(s):  
Shear Modulus ◽  
Room Temperature ◽  
Good Control ◽  
Linear Polymers ◽  
High Concentration ◽  
Gelling Temperature ◽  
Poly Ethylene Oxide ◽  
Cell Biocompatibility ◽  
Poly Ethylene ◽  
Lower Temperature

A series of star and linear polymers based on a poly(ethylene oxide) core and poly(diethylene glycol ethyl ether acrylate) outer arms were synthesised by atom-transfer radical polymerization. The polydispersity of the polymers were low, showing good control of initiation and growth. They all showed lower critical solution (LCST) behaviour, and at 30% concentration most gelled at or below room temperature. The behaviour depended on the number and length of the arms, with the polymers with longer arms gelling at a lower temperature and producing stiffer gels. The shear modulus of the gels varied between 1 and 48 kPa, with the gelling temperature varying between 16 and 23 °C. Attempted cell cultures with the polymers proved unsuccessful, which was determined to be due to the high concentration of polymers needed for gelling.

scholarly journals Effects on the Properties after Addition of Lithium Salt in Poly(ethylene oxide)/Poly(methyl acrylate) Blends

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 2963
Author(s):  
Suhaila Idayu Abdul Halim ◽  
Chin Han Chan ◽  
Jörg Kressler
Keyword(s):  
Ethylene Oxide ◽  
Phase Behavior ◽  
Methyl Acrylate ◽  
Room Temperature ◽  
Electrochemical Impedance ◽  
Lithium Perchlorate ◽  
Ternary Mixtures ◽  
Casting Technique ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

The studies of phase behavior, dielectric relaxation, and other properties of poly(ethylene oxide) (PEO)/poly(methyl acrylate) (PMA) blends with the addition of lithium perchlorate (LiClO4) were done for different blend compositions. Samples were prepared by a solution casting technique. The binary PEO/PMA blends exhibit a single and compositional-dependent glass transition temperature (Tg), which is also true for ternary mixtures of PEO/PMA/LiClO4 when PEO was in excess with low content of salt. These may indicate miscibility of the constituents for the molten systems and amorphous domains of the systems at room temperature from the macroscopic point of view. Subsequently, the morphology of PEO/PMA blends with or without salt are correlated to the phase behavior of the systems. Phase morphology and molecular interaction of polymer chains by salt ions of the systems may rule the dielectric or electric relaxation at room temperature, which was estimated using electrochemical impedance spectroscopy (EIS). The frequency-dependent impedance spectra are of interest for the elucidation of polarization and relaxation of the charged entities for the systems. Relaxation can be noted only when a sufficient amount of salt is added into the systems.

Sign in / Sign up

Export Citation Format

Share Document