scholarly journals A dynamic analysis of viral load, T lymphocyte subsets and main biochemical indexes before and after prevention of mother to child transmission (PMTCT) in HIV/AIDS

2018 ◽  
Vol 2 (4) ◽  
pp. 223-231
Author(s):  
Guosheng Su ◽  
◽  
Yesheng Wei ◽  
Lihua Qin ◽  
Lida Mo
2018 ◽  
Vol 1 (3) ◽  
pp. 1-8
Author(s):  
Naichaya Chamroonkul

Even with two decades of widespread using hepatitis B vaccination, chronic hepatitis B remains a major global health problem. In Thailand, the prevalence of chronic hepatitis B infection was down from 8 - 10% in last decade to 5% recently. Failure to control mother to child transmission is one of the important barriers to the total elimination of hepatitis B infection from world population. In the majority, vertical transmission can be prevented with a universal screening program, immunoprophylaxis by administration of hepatitis B vaccine and hepatitis B immunoglobulin (HBIg) for babies born to mothers with HBV. However, in mothers with a high viral load, the chance of immunoprophylaxis failure remains high. To date, there are standard recommendations by all international liver societies including AASLD, EASL and APASL suggest introducing an antiviral agent during the third trimester to CHB pregnant women with a high viral load. Previous US FDA pregnancy category B agents such as Tenofovir and Telbivudine are allowed through all trimesters of pregnancy and are effective for prevention of mother to child transmission. Breastfeeding for patients who receive antiviral agents can be allowed after a risk-benefit discussion with the patient and family.


Author(s):  
Chandrashekhara Chandrashekhara ◽  
Sandeepkumar O

Children are innocent victims of HIV infection through vertical transmission. Children who are HIV positive, either through mother-to-child transmission or following sexual abuse, are often not told what could happen to them, and they will certainly be frightened when they experience symptoms.


Curationis ◽  
2003 ◽  
Vol 26 (3) ◽  
Author(s):  
L Roets

The transmission of HIV/AIDS from mother to child is the main cause of HIV/AIDS in children and child mortality. Two-thirds of children with HIV/AIDS are infected in the intrapartum period (Farley, 2000:1-2). Midwives, through effective practices, can lower the transmission of HIV/AIDS from mother to child in the intrapartum period. The aim of the study was to determine which preventive practices registered midwives in provincial labour wards in Bloemfontein, implement to lower the risk of mother to child transmission of HIV/AIDS and in doing so to lower child mortality.


Author(s):  
Dr. Shilpa Karir ◽  
Dr. Smita Kumari Panda ◽  
Dr. Sadhu Charan Panda

Globally, around 34 million people are living with HIV in 2010, and 35% of the pregnant women are tested for HIV in the low and middle income countries. HIV infection in pregnancy has become a complication of pregnancy in some developing countries. This has major implications for the management of pregnancy and birth. A cross sectional study was conducted from December 2018 – February 2019 in tertiary care hospital, VIMSAR Burla . The present study was conducted to assess the knowledge about HIV/AIDS and mother to child transmission issues among women seeking antenatal care and visiting ICTC. A sample of 150 pregnant females was used to accomplish the study. A pre- tested semi-structured questionnaire was used to gather information on the study variables. The questionnaire included variables related socio-demographics e.g., age, education status, occupation, residence, awareness about HIV/AIDS. The study reflected that 83.4% of the women had heard of the term HIV/AIDS which reflects a relatively high level of awareness about the term but subsequently dropping levels of awareness about the routes of transmission, laboratory diagnosis and the availability of drugs. Only 45.3% of the respondents were aware of ICTC. 42.7% were aware about mother to child transmission of HIV and only 32% were aware of anti-retro viral therapy for newborn. Keywords: HIV, ICTC, Antenatal


BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e026322 ◽  
Author(s):  
John E Ehiri ◽  
Halimatou S Alaofè ◽  
Victoria Yesufu ◽  
Mobolanle Balogun ◽  
Juliet Iwelunmor ◽  
...  

ObjectiveTo assess AIDS stigmatising attitudes and behaviours by prevention of mother-to-child transmission (PMTCT) service providers in primary healthcare centres in Lagos, Nigeria.DesignCross-sectional survey.SettingThirty-eight primary healthcare centres in Lagos, Nigeria.ParticipantsOne hundred and sixty-one PMTCT service providers.Outcome measuresPMTCT service providers’ discriminatory behaviours, opinions and stigmatising attitudes towards persons living with HIV/AIDS (PLWHAs), and nature of the work environment (HIV/AIDS-related policies and infection-control guidelines/supplies).ResultsReported AIDS-related stigmatisation was low: few respondents (4%) reported hearing coworkers talk badly about PLWHAs or observed provision of poor-quality care to PLWHAs (15%). Health workers were not worried about secondary AIDS stigmatisation due to their occupation (86%). Opinions about PLWHAs were generally supportive; providers strongly agreed that women living with HIV should be allowed to have babies if they wished (94%). PMTCT service providers knew that consent was needed prior to HIV testing (86%) and noted that they would get in trouble at work if they discriminated against PLWHAs (83%). A minority reported discriminatory attitudes and behaviours; 39% reported wearing double gloves and 41% used other special infection-control measures when providing services to PLWHAs. Discriminatory behaviours were correlated with negative opinions about PLWHAs (r=0.21, p<0.01), fear of HIV infection (r=0.16, p<0.05) and professional resistance (r=0.32, p<0.001). Those who underwent HIV training had less fear of contagion.ConclusionsThis study documented generally low levels of reported AIDS-related stigmatisation by PMTCT service providers in primary healthcare centres in Lagos. Policies that reduce stigmatisation against PLWHA in the healthcare setting should be supported by the provision of basic resources for infection control. This may reassure healthcare workers of their safety, thus reducing their fear of contagion and professional resistance to care for individuals who are perceived to be at high risk of HIV.


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