scholarly journals Upper respiratory tract infection and otitis media are clinically and microbiologically associated

2018 ◽  
Vol 1 (1) ◽  
pp. 29-33
Author(s):  
Hanan Raheem Hassooni ◽  
Samih Faiq Fadhil ◽  
Raed M. Hameed ◽  
Adil Hassan Alhusseiny ◽  
Saad Ahmed Ali Jadoo
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Acute Otitis Media ◽  
Chronic Otitis Media ◽  
Cross Sectional Study ◽  
Klebsiella Pneumonia ◽  
Upper Respiratory Tract ◽  
Culture Methods ◽  
Cross Sectional ◽  
Upper Respiratory

Background: Although significant improvement has been achieved in terms of antibiotic care, otitis media (OM) continues to be a worldwide health problem that may develop serious complications. This study aimed to detect the growth of organisms and to find out the most susceptible factors related to OM among the Iraqi population. Methods: A prospective cross-sectional study was conducted at the out-patient department (OPD) of Ear, Nose, and Throat (ENT) at the Baquba teaching hospital at the Faculty of medicine, Diyala University from November 2017 to March 2018. A total of 300 ear samples collected from 87 (29.0%) patients of acute otitis media (AOM), 104 (34.7%) patients of otitis media with effusion (OME), and 109 (36.3%) patients of chronic otitis media (COM). Standard microbiological procedures were recruited to investigate the samples using aerobic and anaerobic culture methods. Results: The highest incidence of OM 218 (72.7%) was observed among the age group of fewer than ten years old. The most common bacteria isolated were Pseudomonas aeruginosa (35.0%), Staphylococcus aureus (25.0%), Proteus spp. (24.0%), Escherichia coli (7.0%), Streptococcus pneumonia (6.0%), Klebsiella pneumonia (2.0%) and Streptococcus pyogenes (1.0%). It was found that upper respiratory infection (URTI), adenoid inflammation with (URTI), adenoid inflammation, the practices of complementary and alternative medicine (CAM), and the accident or trauma are the main factors related to OM in about (42.0%), (31.0%), (11.0%), (10.0%) and (6.0%) of cases respectively. Conclusion: Our findings suggest that OM was effectively related to URTI and adenoid inflammation with (URTI) in about 73.0% of cases. More attention should be given to early diagnosis and treatment of URTI before progressing to undesirable OM.

scholarly journals Ear diseases in school going children of Sunsari and Morang districts of Nepal

2017 ◽  
Vol 7 (1) ◽  
pp. 16-19 ◽  
Author(s):  
Sanjeev Kumar Thakur ◽  
Rabin Acharya ◽  
Sanjay Kumar Singh ◽  
Nisha Ghimire
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Acute Otitis Media ◽  
Chronic Otitis Media ◽  
Health Care Facilities ◽  
Cross Sectional ◽  
Ear Diseases ◽  
Important Health ◽  
Tube Dysfunction ◽  
Ear Wax

This study was carried out to find the prevalence of ear diseases in school-going children of the Sunsari and Morang district of Eastern Nepal. This is a prospective, cross sectional, clinical study in 3729 school going children of up to 15 years of the Sunsari and Morang district of eastern Nepal done in year 2014 and 2015 AD. Informed consent was obtained. 1346 (36.09%) children had different ear ailments. Ear wax 616 (45.76%) and otitis media with effusion 226 (16.79%) were the commonest diseases found. Chronic otitis media mucosal type was found in 104 (7.73%) children. Chronic otitis media squamous 6 (0.45%), Otomycosis 155 (11.51%), otitis externa 16 (1.19%), acute Otitis media 119 (8.84%), Eustachian tube dysfunction 92 (6.84%), Perichondritis 4(0.29%), Foreign body in the ear 2 (0.15%), Preauricular sinus 2 (0.15%) and sensorineural hearing loss 4 (0.29%) were the other diseases found. Ear diseases are important health problems among school-going children of the Sunsari and Morang district of eastern Nepal. Health education,nutrition, improvement of socioeconomic status and health care facilities should be helpful in reducing the prevalence of ear diseases.

scholarly journals Case-Control Microbiome Study of Chronic Otitis Media with Effusion in Children Points at Streptococcus salivarius as a Pathobiont-Inhibiting Species

mSystems ◽  
2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Jennifer Jörissen ◽  
Marianne F. L. van den Broek ◽  
Ilke De Boeck ◽  
Wannes Van Beeck ◽  
Stijn Wittouck ◽  
...  
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Chronic Otitis Media ◽  
Case Control ◽  
Healthy Controls ◽  
Upper Respiratory Tract ◽  
Streptococcus Salivarius ◽  
Healthy Individuals ◽  
Content Type ◽  
Upper Respiratory

ABSTRACT Chronic otitis media with effusion (OME) has been associated with a shift in microbiome composition and microbial interaction in the upper respiratory tract (URT). While most studies have focused on potential pathogens, this study aimed to find bacteria that could be protective against OME through a case-control microbiome study and characterization of isolates from healthy subjects. The URT and ear microbiome profiles of 70 chronic OME patients and 53 controls were compared by 16S rRNA amplicon sequencing. Haemophilus influenzae was the most frequent classic middle ear pathobiont. However, other taxa, especially Alloiococcus otitis, were also frequently detected in the ear canal of OME patients. Streptococci of the salivarius group and Acinetobacter lwoffii were more abundant in the nasopharynx of healthy controls than in OME patients. In addition to the microbiome analysis, 142 taxa were isolated from healthy individuals, and 79 isolates of 13 different Streptococcus species were tested for their pathobiont-inhibiting potential. Of these, Streptococcus salivarius isolates showed a superior capacity to inhibit the growth of H. influenzae, Moraxella catarrhalis, Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, A. otitis, and Corynebacterium otitidis. S. salivarius strains thus show potential as a probiotic for prevention or treatment of OME based on their overrepresentation in the healthy nasopharynx and their ability to inhibit the growth of respiratory pathobionts. (This study has been registered at ClinicalTrials.gov under registration no. NCT03109496.) IMPORTANCE The majority of probiotics marketed today target gastrointestinal health. This study searched for bacteria native to the human upper respiratory tract, with a beneficial potential for respiratory and middle ear health. Comparison of the microbiomes of children with chronic otitis media with effusion (OME) and of healthy controls identified Streptococcus salivarius as a health-associated and prevalent inhabitant of the human nasopharynx. However, beneficial potential should be assessed at strain level. Here, we also isolated specific S. salivarius strains from the healthy individuals in our study. These isolates showed a beneficial safety profile and efficacy potential to inhibit OME pathogens in vitro. These properties will now have to be evaluated and confirmed in human clinical studies.

scholarly journals Persistent adenoids and their secondary effects

2020 ◽  
Vol 6 (7) ◽  
pp. 1245
Author(s):  
Sowmya Tumkur Rangaiah ◽  
Vikram Kemmannu Bhat ◽  
Mona Yadav
Keyword(s):  
Respiratory Tract ◽  
Chronic Rhinosinusitis ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Early Adulthood ◽  
Chronic Otitis Media ◽  
Upper Respiratory Tract ◽  
Secondary Effects ◽  
Tube Dysfunction ◽  
Upper Respiratory

<p class="abstract"><strong>Background:</strong> Regression of adenoids is assumed to be a physiological phenomenon at puberty. However, it has been found that it can persist well beyond adolescence into early adulthood, cascading a series of after effects in the upper respiratory tract that can cause considerable morbidity leading to public health problems. This study aimed to explore the clinicopathological features of persistent adenoids and their secondary effects on the upper respiratory tract.</p><p class="abstract"><strong>Methods:</strong> This was a prospective controlled study of 100 eligible patients in the age group of 15-60 years presenting with enlarged adenoids confirmed by nasal endoscopy. Equal number of controls without enlarged adenoids was also taken. Both the groups were evaluated for secondary effects like chronic rhinosinusitis, otitis media with effusion, chronic otitis media and Eustachian tube dysfunction. The relationship between adenoid enlargement in adults and secondary effects was analysed statistically.  </p><p class="abstract"><strong>Results:</strong> Seventy-seven patients with persistent adenoids had some or the other secondary effect. Eustachian tube dysfunction was present in 21, otitis media with effusion in 10, chronic otitis media in 29 and chronic rhinosinusitis in 33. In the control group only 46 had secondary effects. The association between the presence of adenoids and secondary effects was statistically significant.</p><p class="abstract"><strong>Conclusions:</strong> Adenoids can persist into early adulthood and majority of them can have secondary effects. Chronic rhinosinusitis was the commonest in this study. Careful evaluation by means of nasal endoscopy is required to identify them. This is crucial for the timely treatment of this condition in order to prevent the associated secondary effects.</p>

Otitis Media

PEDIATRICS ◽  
1984 ◽  
Vol 74 (5) ◽  
pp. 948-949
Author(s):  
Charles M. Ginsburg
Keyword(s):  
Otitis Media ◽  
Viral Infections ◽  
Otitis Media With Effusion ◽  
Acute Otitis Media ◽  
Medical Personnel ◽  
Medical Attention ◽  
Common Symptom ◽  
Upper Respiratory Tract ◽  
Primary Responsibility ◽  
Printed Materials

Earache, a common symptom in children, causes many parents to seek medical attention. Aside from trauma and the discomfort that often accompanies viral infections of the upper respiratory tract, acute otitis media with effusion is the commonest cause of otalgia in infants and children. Proper management requires a team effort between the physician and the child's parents or caretaker. The physician must transmit to the parents a concise but thorough overview of the problem and a plan for management. This should include information on the pathophysiology of ear disease, its incidence, therapy and the potential adverse effects, and any measures that the parents may take to prevent recurrence. The primary responsibility for transmittal of this information lies with the physician. Ancillary medical personnel and communication aids (videotapes, computers, printed materials) should be utilized, if available, to reinforce the physician's "message.'

scholarly journals Evaluation of hearing status after type I tympanoplasty

2020 ◽  
Vol 24 (1) ◽  
pp. 50-55
Author(s):  
Mashuque Mahamud ◽  
Mani Lal Aich ◽  
Abdullah Al Mamun ◽  
Rafiul Alam
Keyword(s):  
Otitis Media ◽  
Chronic Otitis Media ◽  
Neck Surgery ◽  
Cross Sectional Study ◽  
Type I ◽  
Cross Sectional ◽  
Female Ratio ◽  
The Mean ◽  
Type I Tympanoplasty ◽  
Air Conduction

Objective: To evaluate hearing outcome after type I tympanoplasty in inactive mucous type of chronic otitis media. Methods: It was a cross-sectional study conducted in the department of Otolaryngology & Head Neck Surgery, Sir Salimullah Medical College and Mitford Hospital, Dhaka, from July 2014 to June 2016. 50 cases were selected by matching inclusion and exclusion criteria. Paired t-test and Z test was used to analyze the variables. P values <0.05 was considered as statistically significant. Results: The mean age was found 28.5 years with range from 15 to 41 years and male female ratio was 1.3:1. All patients had intermittent otorrhoea and varying degree of hearing loss. The mean air conduction threshold was 40.2 dB preoperatively and 27.1 dB post-operatively. Air-bone gap was found 26.9 dB in preoperative and 16.1 dB in post-operative group. The differences were statistically significant between preoperative and post-operative group. Thus mean improvement of air conduction threshold was 13.1 dB and air-bone gap was 10.8 dB. Two third (66.%) patients improved <15 db air conduction thresholds and 17(34%) improved ≥15 db air conduction thresholds. Using the proportion of patients with a postoperative hearing within 40 dB as the criterion, this study showed 46(92%) patients achieving this and 40(80%) patients achieving AB gap within 20 db postoperatively. Conclusion: Improvement of air conduction threshold and AB gap after type I tympanoplasty was statistically significant. Thus from this study it can be concluded that type I tympanoplasty is an effective technique for hearing improvement in inactive mucous type of chronic otitis media. Bangladesh J Otorhinolaryngol; April 2018; 24(1): 50-55

scholarly journals A cross sectional study on prescription pattern of drugs in upper respiratory tract infections in a tertiary care hospital

2020 ◽  
Vol 9 (2) ◽  
pp. 271
Author(s):  
Divya Bade ◽  
Shivashankaramurthy K. G. ◽  
Kiran L. J. ◽  
Raghuprasada M. S. ◽  
Harishkumar V. S. ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Cross Sectional Study ◽  
Prescribing Patterns ◽  
Essential Medicines ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Cross Sectional ◽  
Upper Respiratory ◽  
Tract Infections

Background: Upper respiratory tract infections are one of the leading causes of hospital visits worldwide. Judicious use of antibiotics is challenging for upper respiratory tract infections (URTIs) in developing countries like India. This leads to inappropriate use of antibiotics causing many dreaded conditions like antibacterial resistance among other things. Hence rational use of drugs, mainly antibacterial, is a priority to reduce the burden of treatment failure. The objective of this study is to study the prescribing patterns and rationality of drugs prescribed in the management of URTIs.Methods: This was a cross-sectional study. Data was collected from records of 300 outpatients clinically diagnosed as URTIs from SSIMS and RC Hospital, Davangere between January 2015 and June 2016. The prescribing patterns, approval status and listing of drugs in World Health Organization (WHO) essential medicines list/ National List of Essential Medicines (NLEM) were analysed. The data was presented as percentages, mean and standard deviations.Results: A total of 300 cases were studied. Among these, acute pharyngitis (29%) and acute sinusitis (26%) are the most common infections. Of the 300 cases studied, 283 (94.3%) were prescribed antimicrobials. Of the total 740 medications prescribed, 393 (53.1%) were fixed-dose combinations (FDCs). A total of 724 medications (97.8%) were approved by Drugs Controller General of India and 248 (33.5%) by Food and Drug Administration. Only 5.8% of the prescribed drugs have been listed in WHO’s and NLEM. The most common class of antibacterials prescribed was Beta-lactams.Conclusions: Oral formulations were preferred over parenteral formulations and FDCs were preferred over single drug formulations. Beta-lactams comprised the major class of antibacterial prescribed.

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