scholarly journals Serum fructosamine targeting the treatment of gestational diabetes mellitus

2021 ◽  
pp. 5-10
Author(s):  
Le Huy Truong ◽  
Van Chi Le
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Blood Glucose Control ◽  
Reference Value ◽  
Diabetic Patients ◽  
Delivery Outcome ◽  
Serum Fructosamine ◽  
A Prospective Study ◽  
Pregnant Diabetic

Background: Currently,the blood glucose control in women with gestational diabetes (GDM) in Vietnam has been still based on the criteria applied for non-pregnant diabetic patients, while these GDM patients require more specific criteria in order to get a better care of the women and the good delivery outcome. Objective: To determine serum fructosamine target as a supporting test for the treatment and follow-up of GDM. Methodology: A prospective study was done in 451women with GDM at Cho Ray Hospital from  August 2016 to March 2019.At least 2 of 3 tests (Go, G2 and HbA1c) and serum fructosamine were determined every 2-3 week-up until delivery. Result: The target fructosamine reference value at Cho Ray Hospital was 188.5±42.3µmol/L. Conclusion: The specific target of serum fructosamine  in GDM treatment at Cho Ray hospital should be £188.5 ± 42.3mmol/L.

scholarly journals DIABETES MELLITUS MODIFYING FACTORS;

2014 ◽  
Vol 21 (06) ◽  
pp. 1185-1190
Author(s):  
Safirah Maheen ◽  
Haroon-ur- Rashid ◽  
Khan Mohammad Baber ◽  
Hafeez ullah Khan ◽  
Ambreen Malik Uttra ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Sampling Method ◽  
Diabetic Patients ◽  
Dietary Recommendations ◽  
Modifying Factors ◽  
Convenience Sampling ◽  
Healthy Activity ◽  
A Prospective Study ◽  
Structured Questionnaire

Objective: Diabetes mellitus is wide spread non transmissible disease but its prevalence is increasing everyday so this study was conducted with an aim to investigate the factors that are modifying diabetes mellitus among patients at DHQ (District Head Quarter) Hospital Sargodha. Methodology: A prospective study was carried out by well-trained pharmacists in DHQ Sargodha, Pakistan to assess the factors modifying diabetes mellitus. Data was collected from 110 patients randomly by using convenience sampling method. A well structured questionnaire was designed to collect information from patients and entire procedure was conducted with the permission of concerned authorities of Hospital management. The factors that are considered in present study are medication, treatment, patient physician interaction and society attitude towards diabetic patients which are helpful in halting the progression of diabetes and prevention of co morbidities. Results: The results of study disclose that 74.5% diabetic patients felt better after treatment whereas 56% diabetic patients were satisfied with the information provided by physician to them but still 70% patients were suffering from co morbidities. The survey indicated that 62.7% patients said that exercise proved to be healthy activity in improving diabetes. However 59% diabetic patients were following a proper diet plan which was helpful in modifying their diabetes. Conclusions: The diabetic patients must be informed about importance of regular follow-up in averting long-standing complications. Patients should be guided about importance of dietary recommendations, exercise and strict metabolic control, that can holdup or avert the series of complications allied with diabetes.

scholarly journals The effect of diabetes mellitus on evolution and outcome of tuberculosis in a prospective study

2021 ◽  
Vol 64 (5) ◽  
pp. 16-20
Author(s):  
Alina Malic ◽  
◽  
Evelina Lesnic ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Prospective Study ◽  
Treatment Effectiveness ◽  
Similar Rate ◽  
Control Group ◽  
Diabetic Patients ◽  
A Prospective Study ◽  
Prospective Longitudinal ◽  
The Impact

Background: In the Republic of Moldova almost 5% of the cases with tuberculosis are diagnosed annually among diabetic patients. The aim of this study was to assess the impact of diabetes mellitus on the evolution and anti-tuberculosis treatment effectiveness in a prospective study. Material and methods: A prospective, longitudinal and case-control study, which included a total number of 252 patients diagnosed with pulmonary tuberculosis and distributed in a study group, consisting of 93 patients diagnosed with diabetes mellitus and a control group, consisting of 159 patients without glycemic disorders, was performed. Results: This study identified that one half of the group with diabetes was detected by active screening and one third received anti-tuberculous treatment before actual episode. A similar rate of diabetic and non-diabetic patients was microbiologically positive, as well confirmed with drug-resistance. The anti-tuberculous treatment effectiveness was lower in diabetic patients, the death rate and the low treatment outcome (lost to follow-up and failed) were higher than in non-diabetic patients. The main causes of unfavorable evolution were: glycemic disorders (hyperglycemia), diabetes complications and the history of the anti-tuberculous treatment in the anamnesis. Conclusions: The individualized approach and a tight follow-up should be performed regularly in all patients with glycemic disorders and tuberculosis for the improvement of the disease outcome.

scholarly journals Gestational Diabetes Mellitus and Renal Function: A Prospective Study With 9- to 16-Year Follow-up After Pregnancy

Diabetes Care ◽  
2018 ◽  
Vol 41 (7) ◽  
pp. 1378-1384 ◽  
Author(s):  
Shristi Rawal ◽  
Sjurdur F. Olsen ◽  
Louise G. Grunnet ◽  
Ronald C. Ma ◽  
Stefanie N. Hinkle ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Function ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Prospective Study ◽  
A Prospective Study

Postpartum Tip 2 DM follow-up after gestational diabetes mellitus

2017 ◽  
Author(s):  
Seda Sancak ◽  
Ali Ozdemir ◽  
Kerem Yiğit Abacar ◽  
Ayhan Celik ◽  
Nalan Okuroğlu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus

scholarly journals Metabolic signatures in the conversion from gestational diabetes mellitus to postpartum abnormal glucose metabolism: a pilot study in Asian women

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xi-Meng Wang ◽  
Yan Gao ◽  
Johan G. Eriksson ◽  
Weiqing Chen ◽  
Yap Seng Chong ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Metabolism ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Post Partum ◽  
Diagnostic Biomarkers ◽  
Serum Metabolites ◽  
Abnormal Glucose Metabolism ◽  
Metabolic Signatures

AbstractWe aimed to identify serum metabolites related to abnormal glucose metabolism (AGM) among women with gestational diabetes mellitus (GDM). The study recruited 50 women diagnosed with GDM during mid-late pregnancy and 50 non-GDM matchees in a Singapore birth cohort. At the 5-year post-partum follow-up, we applied an untargeted approach to investigate the profiles of serum metabolites among all participants. We first employed OPLS-DA and logistic regression to discriminate women with and without follow-up AGM, and then applied area under the curve (AUC) to assess the incremental indicative value of metabolic signatures on AGM. We identified 23 candidate metabolites that were associated with postpartum AGM among all participants. We then narrowed down to five metabolites [p-cresol sulfate, linoleic acid, glycocholic acid, lysoPC(16:1) and lysoPC(20:3)] specifically associating with both GDM and postpartum AGM. The combined metabolites in addition to traditional risks showed a higher indicative value in AUC (0.92–0.94 vs. 0.74 of traditional risks and 0.77 of baseline diagnostic biomarkers) and R2 (0.67–0.70 vs. 0.25 of traditional risks and 0.32 of baseline diagnostic biomarkers) in terms of AGM indication, compared with the traditional risks model and traditional risks and diagnostic biomarkers combined model. These metabolic signatures significantly increased the AUC value of AGM indication in addition to traditional risks, and might shed light on the pathophysiology underlying the transition from GDM to AGM.

scholarly journals Patient counseling increases postpartum follow-up in women with gestational diabetes mellitus

2011 ◽  
Vol 204 (6) ◽  
pp. 522.e1-522.e6 ◽  
Author(s):  
Marina Stasenko ◽  
Jennifer Liddell ◽  
Yvonne W. Cheng ◽  
Teresa N. Sparks ◽  
Molly Killion ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Patient Counseling
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