scholarly journals A Hospital based cross sectional study to find out factors associated with disease severity and length of hospital stay in COVID-19 patients in Tertiary Care Hospital of Ahmedabad city

2021 ◽  
Vol 33 (2) ◽  
pp. 256-259
Author(s):  
Arpit Chelabhai Prajapati ◽  
Mansi Maulik Patel ◽  
Hardika Jamanadas Khanpara ◽  
Rujul Pankajbhai Shukla ◽  
Donald Shailendra Christian ◽  
...  

Background: Tertiary hospital care may vary from isolation bed ward care to high dependency units (HDUs) with oxygen support to intensive care unit (ICU) where patients may be intubated for mechanical ventilation The major risk factors for severe disease are age more than 60 years and underlying diseases like diabetes, hypertension. COVID-19 patients present at varying levels of severity. Understanding how long patients hospitalized with COVID-19 remain in hospital is critical for planning. Objectives: 1. To determine risk factors associated with disease severity 2. To determine risk factors associated with length of hospital stay in COVID-19 patients 3. To study the disease outcome Material & Methods: This was retrospective record-based study of inpatients with COVID-19 at Tertiary Care Hospital of Ahmedabad City. All patients admitted at tertiary care hospital diagnosed with COVID-19 between April 2020 to June, 2020, were included in present study. Inclusion criteria were all COVID-19 patients admitted at tertiary care hospital during the duration of April 2020 to June 2020. Results: A total of 916 COVID-19 patients were included in the study. Out of 916 total admitted patients 526 (57.4%) were male. 174 (19%) patients having one or more comorbidities like diabetes, hypertension, tuberculosis, heart diseases etc. Total 769 discharged (83.9%), 115 deaths (12.6%) and 32 transferred to other COVID-19 hospital (3.5%) out of total 916 patients admitted during study period. Conclusion: Severity of disease and deaths were associated with age and comorbidities. COVID-19 patients with comorbidities have more deteriorating outcomes compared with patients without.

2010 ◽  
Vol 19 (6) ◽  
pp. 463-467 ◽  
Author(s):  
Ilknur Erdem ◽  
Naz Oguzoglu ◽  
Derya Ozturk Engin ◽  
Asu Ozgultekin ◽  
Asuma Sengoz Inan ◽  
...  

2020 ◽  
Vol 81 (1) ◽  
pp. e95-e97 ◽  
Author(s):  
Xiaofan Liu ◽  
Hong Zhou ◽  
Yilu Zhou ◽  
Xiaojun Wu ◽  
Yang Zhao ◽  
...  

2021 ◽  
Vol 9 (3) ◽  
pp. 98
Author(s):  
Shamsul Alam ◽  
Erfanul Huq Siddiqui ◽  
Sheikh Forhad ◽  
Anjumun Ara ◽  
Jannat Sultana

Chemotherapy ◽  
2012 ◽  
Vol 58 (3) ◽  
pp. 217-224 ◽  
Author(s):  
Sissy Muro ◽  
Elvira Garza-González ◽  
Adrian Camacho-Ortiz ◽  
Gloria María González ◽  
Jorge Martín Llaca-Díaz ◽  
...  

2013 ◽  
Vol 5 (1) ◽  
pp. e2013014 ◽  
Author(s):  
Muhammad Imran Hasan Khan ◽  
Eram Anwar ◽  
Adnan Agha ◽  
Noha Saleh ◽  
Ehsan Ullah ◽  
...  

Introduction: Dengue virus (DENV) affects over half the world’s population in 112 countries, and dengue fever (DF) is the second largest arthropod borne infectious global hazard after malaria with complications like Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) accounting for significant morbidity and mortality world over. Pakistan is significantly affected with DENV infection and to-date no study identifying risk factors associated with complications of DF has been done. Methods: 997 confirmed cases of DF were collected in a tertiary care hospital in Lahore, Pakistan and their clinical and biochemical data were collected. Univariate, multivariate and logistics regression analysis was performed to identify risk factors associated with development of DHF and DSS. Results: Bleeding OR 70.7 (CI 38.4-129.9), deranged liver function test OR 1.9 (CI 0.97-0.99), platelet count on admission less than 50,000 x109/L OR 0.16 (CI 0.13-0.19), presence of urinary red blood cells OR 1.4 (CI 0.179-0.900) and presence of urinary protein OR 1.1 (CI 0.191-0.974) were related to development of DHF and DSS.


PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e10826
Author(s):  
Amna Saifullah ◽  
Tauqeer Hussain Mallhi ◽  
Yusra Habib Khan ◽  
Muhammad Shahid Iqbal ◽  
Nasser Hadal Alotaibi ◽  
...  

Background Drug resistant tuberculosis (DR-TB) infringes substantial burden in terms of longer treatment duration, morbidity and mortality. Timely identification of patients at risks of DR-TB will aid individualized treatment. Current study was aimed to ascertain several factors associated with DR-TB among patients attending a tertiary care hospital. Methods This retrospective study was conducted among patients with confirmed diagnosis of DR-TB and drug susceptible TB (DS-TB) seeking medical care from a tertiary care hospital during 2014–2019. The types of DR-TB included were rifampicin resistant tuberculosis (RR-TB), Multidrug resistant tuberculosis (MDR-TB) and extensively drug resistant tuberculosis (XDR-TB). Appropriate statistical methods were implied to evaluate the factors associated with DR-TB. Results Out of 580 patients, DS-TB was diagnosed in 198 (34.1%) patients while DR-TB was present in 382 patients. Of resistance cases, RR-TB, MDR-TB and XDR-TB were diagnosed in 176 (30.3%), 195 (33.6%) and 11 (1.9%) patients, respectively. Significant differences (P < 0.05) in demographics and clinico-laboratory characteristics were observed between patients with DS-TB and DR-TB. Logistic regression analysis revealed age ≤38 years (OR: 2.5), single marital status (OR: 11.1), tobacco use (OR: 2.9), previous treatment (OR: 19.2), treatment failure (OR: 9.2) and cavity on chest X-ray (OR: 30.1) as independent risk factors for MDR-TB. However, XDR-TB was independently associated with age group of ≤38 years (OR: 13.6), students (OR: 13.0), previous treatment (OR: 12.5), cavity on chest X-ray (OR: 59.6). The independent risk factors associated with RR-TB are age ≤38 years (OR: 2.8), females (OR: 5.7), unemployed (OR: 41.5), treatment failure (OR: 4.9), previous treatment (OR: 38.2) and cavity on chest X-ray (OR: 4.3). ROC curve analysis accentuate the excellent predictive accuracy of all logistic regression models as shown by AUC (0.968, P < 0.001) for MDR-TB, AUC (0.941, P < 0.001) for XDR-TB and AUC (0.962, P < 0.001) for RR-TB. Conclusions Current study demonstrates a sizeable extent of resistant cases among pulmonary TB patients. This study presaged significant risk of DR-TB among females, young adults, unemployed, smokers, patients with previous treatment failure and cavitation on chest X-ray. Timely identification of high risk patients will give pronounced advantages regarding appropriate choices of prevention, treatment and disease control.


2020 ◽  
Vol 6 (3) ◽  
pp. 16-19
Author(s):  
Hira Bakhtiar ◽  
Maria Malik A. Khaliq ◽  
Asif Nawaz ◽  
Muhammad Asif ◽  
Siraj Jamil ◽  
...  

Introduction: Postpartum depression has become a common complication in women in their postpartum period, affecting not only the mother but her child and her family. Due to lack of awareness regarding the subject it has been widely neglected, especially in Pakistan.Objective: To determine and compare the frequency and risk factors associated with postpartum depression in a public and a private tertiary care hospital in Peshawar.Materials & Methods: A comparative cross-sectional study was conducted in the Gynecology and Pediatrics OPD and Pediatrics ward of Rehman Medical Institute (RMI) and Gynecology and Pediatrics OPD as well as the vaccination center of Hayatabad Medical Complex (HMC) over a period of 6 months (January to June 2016). The women were interviewed after obtaining informed consent during 1-12 months of their postpartum period using the Edinburgh Postnatal Depression Scale (EPDS) as well as a pretested self-structured questionnaire. Chi Square test and binary logistic regression were used to determine the relative significance of various risk factors for PPD.Results: A total of 280 women were interviewed, 140 in each hospital, their ages ranging from 16 to 45 years. The frequency of PPD calculated at RMI was 62.7% and at HMC it was 37.3% (p=0.001). Risk factors that showed a close association with PPD included the level of education of women (p=0.008), family support (p=0.022), and history of previous trauma (p= 0.055).Conclusion: Postpartum depression is twice as likely to occur in a private tertiary care hospital compared to a public one, and appears related to educational status, family help, and history of trauma.Keywords: Depression, Postpartum; Postpartum Period, Mothers; Child; Breast Feeding; Childbirth


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