scholarly journals Anxiety, depression and stress tension screening in patients with rheumatic and musculoskeletal diseases at the onset of the 2019 coronavirus disease (COVID-19) pandemic

2021 ◽  
Vol 59 (6) ◽  
pp. 676-683
Author(s):  
A. B. Borisova ◽  
T. A. Lisitsyna ◽  
D. Yu. Veltishchev ◽  
E. L. Nasonov

The aim - screening of anxiety, depression and stress in patients with rheumatic and musculoskeletal diseases (RMD) and medical workers at the beginning of the COVID-19.Material and methods. 150 patients (men/women: 39 (26.0%)/111 (74.0%); mean age - 43.2±16.1 years) with RMD, hospitalized at the V.A. Nasonova Research Institute of Rheumatology (Moscow) from July to November 2020, and 32 relatively healthy medical workers (men/women: 3 (9.38%)/29 (90.6%), mean age - 40.7±14.6 years) as a control group was included in the study. The Hospital Anxiety and Depression Scale (HADS) and the Depression Anxiety and Stress Scale - 21 Items (DASS-21) were used for anxiety, depression and stress screening. Results. Frequency of anxiety-depressive spectrum disorders in patients with RMD was 48% (according to DASS-21) and 27.2% (according to HADS), which did not differ significantly from the control group - 46.9% and 18.8% respectively. According to the DASS-21, patients with systemic sclerosis were significantly more likely to have a combination of clinically significant anxiety, depression and stress compared to healthy control (6 (46.2%) vs 4 (12.5%); p=0.02) and patients with spondyloarthritis (6 (46.2% vs 5 (16.1%); p=0.045). The severity of anxiety was significantly higher among patients with RMD - systemic lupus erythematosus, primary Sjogren's syndrome and systemic sclerosis, according to both scales. The severity of depression, anxiety and stress was significantly higher in women with RMD, rural residents and patients taking moderate and high doses of glucocorticoids. The pathological stress level was experienced by younger medical workers (27.5±5.45 vs 45.8±13.8 years; p=0.001). The transferred coronavirus infection did not lead to an increase in the severity of depression, anxiety and stress tension among patients, however, among medical workers, the frequency of clinically significant anxiety (4 (57.1%) vs 6 (24%)) and stress (3 (42.8%) vs 5 (20%)) was 2.2-2.9 times higher in those who have been ill. When compared with the results of the similar screening by HADS in 2012, the proportion of RМD-patients with clinically significant anxiety and depression over the past 8 years and in connection with the pandemic COVID-19 has not significantly changed.Conclusion. A new threat to health, isolation and uncertainty at the beginning of the COVID-19 were an additional stressful factor for patients with RМD, however, given the high background prevalence of low-severity chronic depression with frequent onset before RМD, the factor of the COVID-19 is not a key factor in provoking mental disorders.

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1114.2-1114
Author(s):  
M. Letaeva ◽  
M. Koroleva ◽  
J. Averkieva ◽  
O. Malyshenko ◽  
T. Raskina

Objectives:to assess the frequency of occurrence of the anxiety-depressive spectrum in patients with rheumatoid arthritis and ankylosing spondylitis.Methods:A survey was conducted of 44 patients aged from 21 to 57 years (average age - 42.3 ± 6.7 years), who were treated at GAUZ KO OKGVV. All patients had a verified diagnosis of RA and AS according to the ACR criteria and received treatment with basic drugs. The control group consisted of 40 people comparable in age and sex, without concomitant pathology of RA and AS.The depression screening card, the subjective well-being scale, and the hospital anxiety and depression scale (HADS) were used to assess and detect anxiety-depressive syndrome. The assessment of the condition is carried out over the last 2 weeks, which corresponds to the temporary diagnostic criterion for depression.The Depression Screening Scale is a 35-item self-questionnaire that assesses 7 categories of signs: sleep and appetite disorders, anxiety, emotional instability, cognitive impairment, loss of self, guilt, and suicidal tendencies. A total score of 65 and above indicates a high likelihood of depression.The Subjective Well-Being Scale is a psychodiagnostic screening tool for measuring the emotional component of subjective well-being or emotional comfort.Hospital Anxiety and Depression Scale Zigmond A.S., Snaith R.P. was developed for the primary detection of depression and anxiety in a general medical practice. The HADS scale consists of 14 statements with 4 possible answers and includes two parts: anxiety and depression. The sum of points of 8 or more is regarded as “subclinically expressed anxiety / depression”, 11 or more points - “clinically expressed anxiety / depression”.Results:According to the results of the depression screening questionnaire, 34 (77.3%) patients with RA and AS showed signs of depression, while in the control group only 6 (15%) patients tested positive for the presence of depressive disorders. According to the data obtained when assessing the scale of well-being in the main group, 26 (59.1%) patients showed signs of emotional discomfort (the indicator was 80% or more), in the control group - in 6 (15%). Using the hospital scale of anxiety and depression HADS, anxiety-depressive syndrome was detected in 36 (81.8%) patients with RA and AS: 16 (44.4%) patients had anxiety, 20 (55.6%) - depression, of them, subclinically expressed anxiety and depression were observed in 10 (27.7%) and 12 (33.3%) people, respectively. Anxiety-depressive syndrome in the control group, according to the HADS questionnaire, was detected only in 8 (20%) patients, of whom 4 (10%) patients had subclinical anxiety and 4 (10%) had signs of depression. No clinically pronounced anxiety and depression were registered in the control group.Conclusion:In most patients with rheumatoid arthritis and ankylosing spondylitis, anxiety-depressive disorders have been identified, which can directly affect both the course of the disease itself and the development of various complications. Timely diagnosis of mental disorders and close cooperation of rheumatologists, psychiatrists and psychologists in the selection of adequate therapy can improve the course and prognosis of the disease.Disclosure of Interests:None declared


2017 ◽  
Vol 28 (6) ◽  
pp. 726-743 ◽  
Author(s):  
Mei-Hua Kao ◽  
Pi-Feng Hsu ◽  
Sheng-Fang Tien ◽  
Chie-Pein Chen

This study was to examine the effects of support interventions on anxiety, depression, and quality of life in women hospitalized with preterm labor. A randomized, single-blind experimental design was used. Participants were recruited from maternity wards of one medical center in Taiwan. The control group ( n = 103) received routine nursing care, and intervention group ( n = 140) received interventional support during hospitalization. The Beck Anxiety Inventory, Edinburgh Postnatal Depression Scale, and Quality of Life Enjoyment and Satisfaction Questionnaire were used at admission and 2 weeks of hospitalization. For the control group, anxiety and depression scores increased significantly and quality of life decreased 2 weeks after hospitalization. Participants who received 2 weeks of support intervention had significantly lower anxiety and depression scores than controls. Thus, clinical nurses can offer support interventions to improve anxiety and depression for women with preterm labor during hospitalization.


2018 ◽  
Vol 41 (9) ◽  
pp. 1254-1269
Author(s):  
Chunyan Nie ◽  
Tianzhu Li ◽  
Xiaoxia Guo

The objective of this article is to investigate the effects of intensive patients’ education and lifestyle improving program (IPEL) on anxiety, depression, and overall survival (OS) in coronary artery disease (CAD) patients with anxiety and depression. In all, 224 CAD patients with anxiety and depression were randomly assigned to IPEL or control group. In Stage I, the IPEL group received IPEL and usual care, while the control group only received usual care. In Stage II, patients were further followed up and OS analysis was performed. Hospital Anxiety and Depression Scale–anxiety (HADS-A) and HADS–depression (HADS-D) were used to assess anxiety and depression. IPEL reduced HADS-A score at Month 9 (M9)/M12, and the percentage of anxiety at M12 and HADS-A score changed. IPEL reduced HADS-D score at M12, and the percentage of depression at M12 and HADS-D score changed compared with control. Patients with nonanxiety/nondepression at M12 in the IPEL group showed better OS. IPEL reduces anxiety and depression and improves OS in CAD patients.


Author(s):  
Maria E. Loades ◽  
Rebecca Read ◽  
Lucie Smith ◽  
Nina T. Higson-Sweeney ◽  
Amanda Laffan ◽  
...  

Abstract Adolescents with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) appear to be more likely to experience anxiety and/or depression using Patient Reported Outcome Measures (PROMs). However, we do not know how accurate these are at detecting problems in this patient group given the primary symptom of fatigue. We aimed to accurately determine the prevalence of anxiety/depression using gold-standard diagnostic interviews and evaluate the accuracy of PROMs measuring mood disorders in this patient group. We conducted a cross-sectional epidemiological study in a specialist tertiary paediatric CFS/ME service, England. The participants were164 12–18-year olds with clinician confirmed CFS/ME and their parents. The measures were a semi-structured diagnostic interview, the Kiddie Schedule for Affective Disorders and Schizophrenia, K-SADS, and questionnaires (Revised Children’s Anxiety and Depression Scale, RCADS; Spence Children’s Anxiety Scale, SCAS; Hospital Anxiety and Depression Scale, HADS). Parents completed the RCADS-P. 35% met the criteria for at least one common mental health problem. 20% had major depressive disorder, and 27% an anxiety disorder, with social anxiety and generalised anxiety being the most common. There was high co-morbidity, with 61% of those who were depressed also having at least one anxiety disorder. The questionnaires were moderately accurate (AUC > 0.7) at detecting clinically significant anxiety/depression, although only the RCADS-anxiety reached the predefined 0.8 sensitivity, 0.7 specificity target. Mental health problems are particularly common amongst adolescents with CFS/ME. Most screening tools were not sufficiently accurate in detecting clinically significant anxiety and depression, so these should be used with care in combination with thorough psychological/psychiatric assessment.


Cephalalgia ◽  
2003 ◽  
Vol 23 (6) ◽  
pp. 451-455 ◽  
Author(s):  
C Wacogne ◽  
JP Lacoste ◽  
E Guillibert ◽  
FC Hugues ◽  
C Le Jeunne

This study investigated the intensity of stress, anxiety and depression in a sample of 141 migraineurs compared with a control group of 109 non-migraine workers matched for age and sex. Stress was measured using the Perceived Stress Questionnaire, and anxiety and depression using the Hospital Anxiety and Depression Scale. Results indicated that stress and anxiety were higher in the migraine group than in the control group and above the clinical level. Depression scores remained low in both groups, under clinical relevance. Stress is a primordial factor in the triggering and perpetuation of migraine attacks. The high score of the items ‘morning fatigue’, ‘intrusive thoughts about work’, ‘feeling under pressure’, ‘impatience’, and ‘irritability’ of the stress questionnaire in the migraineurs is particularly significant in the intensive stress response. It seems necessary to manage stress to improve the daily life of migraineurs and to study the link between stress, anxiety and migraine.


2012 ◽  
Vol 24 (10) ◽  
pp. 1622-1632 ◽  
Author(s):  
Osvaldo P. Almeida ◽  
Brian Draper ◽  
Jane Pirkis ◽  
John Snowdon ◽  
Nicola T. Lautenschlager ◽  
...  

ABSTRACTBackground: This study aimed to determine: (1) the prevalence of depression, anxiety, and depression associated with anxiety (DA); (2) the risk factor profile of depression, anxiety, and DA; (3) the course of depression, anxiety, and DA over 24 months.Methods: Two-year longitudinal study of 20,036 adults aged 60+ years. We used the Patient Health Questionnaire and the Hospital Anxiety and Depression Scale anxiety subscale to establish the presence of depression and anxiety, and standard procedures to collect demographic, lifestyle, psychosocial, and clinical data.Results: The prevalence of anxiety, depression, and DA was 4.7%, 1.4%, and 1.8%. About 57% of depression cases showed evidence of comorbid anxiety, while only 28% of those with clinically significant anxiety had concurrent depression. There was not only an overlap in the distribution of risk factors in these diagnostic groups but also differences. We found that 31%, 23%, and 35% of older adults with anxiety, depression, and DA showed persistence of symptoms after two years. Repeated anxiety was more common in women and repeated depression in men. Socioeconomic stressors were common in repeated DA.Conclusions: Clinically significant anxiety and depression are distinct conditions that frequently coexist in later life; when they appear together, older adults endure a more chronic course of illness.


Author(s):  
E. V. Zhovnerchuk ◽  
I. V. Bukhtiyarov ◽  
D. E. Khatin ◽  
A. V. Moskovenko ◽  
V. V. Serikov ◽  
...  

Introduction. Depression and anxiety, observed in general medical practice, can lead to maladaptive states that reduce performance, and contributes to the manifestation of various psychosomatic disorders. Therefore, timely diagnosis of these disorders in many cases becomes an important condition for the success of medical care and the patient’s return to work. Clinical manifestations of occupational and work-related diseases are often accompanied by anxiety and depressive symptoms, which can occur as a comorbid mental disorder or be affective inclusion.The aim of the study is to explore the distribution and severity of secondary anxiety and depression in the provision of special inpatient medical care in the field of occupational pathology by conducting a screening examination and develop practical recommendations for diagnosis.Materials and methods. The hospital’s HADS anxiety and depression scale and Beck’s depression scale were used to test for indications of secondary anxiety and depression in the incoming patient stream (n=260). Correlation analysis was used to study the dependence of the severity of anxiety values on the severity of depression values and the severity of anxiety and depression on the age of patients. Using the Mann-Whitney criterion, a comparison was made between a sample of respondents with anxiety and depression values and a control group with normal indicators for all disease groups according to ICD–10. Also, in the General sample and separately for a group of men and women, three groups of diseases were compared — professional, production-related, and others.Results. In the risk group of 94 patients with severe symptoms of anxiety (10.9±2.84) and depression (10.2±1.9), 67% were women. This group has higher rates of anxiety and depression in the HADS survey compared to the group of men (33%, p<0.001). The dependence of the severity of anxiety signs on the severity of depression signs for the joint sample of men and women was 0.337 (p≤0.05). Separately, for a group of women, 0.251 (p≤0.05) and for a group of men, 0.252 (p≤0.05). This suggests that as anxiety increases, the severity of depression may also increase. The relationship between the patient’s age and the severity of his symptoms of anxiety 0.144 (p≤0.05) and depression 0.1199 (p≤0.05) confirms the trend towards this relationship. The distribution of anxiety and depression indicators among patients with occupational and work-related pathology showed a predominance of anxiety values in professional (10.5±2.4) and work-related (11.8±3.2) diseases in the group of women. The prevalence of depression in professional (10.5±2.4) and production-related (10.4±2) diseases was also detected in the group of women. Criterion for the difference between a sample of respondents with anxiety and depression values and a control group with normal indicators for all disease groups according to ICD–10 (p<0.001). Differences in depression indicators between groups of occupational and work-related diseases (p=0.08) indicate that patients with occupational diseases have more pronounced values on the depression scale. Women with occupational and work-related diseases have much higher depression values than women with other diseases (p=0.02). Thus, women with occupational and workrelated diseases have higher indicators of anxiety and depression scales than men.Conclusions. Screening examination for signs of anxiety and depression in the provision of special inpatient medical care in the profile of occupational pathology, revealed increased indicators of anxiety and depression in the group of women. As the severity of anxiety indicators increases, so does the severity of depression indicators. The dependence of anxiety and depression indicators on the age of patients confirms the tendency to this dependence. The distribution of anxiety and depression indicators among patients with occupational and work-related pathology showed the predominance of the value of anxiety in professional and work-related diseases in the group of women. The predominance of indicators of depression in occupational and work-related diseases was also found in the group of women. In the female group, patients with occupational and work-related diseases have much higher rates of depression than patients with other diseases. Thus, women with occupational and work-related illnesses are more likely to experience anxiety and depression than men. The development of practical recommendations for the diagnosis of signs of anxiety and depression is reduced to psycho-educational work to prevent negative stigmatization of issues related to mental health, conducting timely examinations with elements of bioinformatics modeling and using a system to support medical decision-making.


2017 ◽  
Vol 41 (S1) ◽  
pp. S736-S737 ◽  
Author(s):  
M.H. Kao ◽  
C.P. Chie-Pein Chen

AimTo examine the effects of support interventions on anxiety, depression in women hospitalized with preterm labour at admission and 2 weeks.BackgroundHospitalized pregnant women with preterm labour have significantly higher anxiety and depression levels. Few studies have explored the effects of support interventions on anxiety, depression in such women.MethodsA randomized, single-blind experimental design was used. The control group (n = 103) and intervention group (n = 140) were recruited from the maternity wards of one medical centre in northern Taiwan between January 2013 and April 2015. The control group received routine nursing care. The experimental group received support interventions, which included an interview, distraction methods and assistance with daily living needs. Groups were evaluated with the Beck anxiety inventory, Edinburgh Postnatal Depression Scale and at admission and 2 weeks of hospitalization.ResultsThere were no significant differences between groups for demographics, obstetric characteristics, or birth outcomes. For the control group, anxiety and depression scores increased significantly decreased 2 weeks after hospitalization. The intervention group had a small, but significant, increase in anxiety and no significant change in depression at 2 weeks. Participants who received 2 weeks of support intervention had significantly lower anxiety and depression scores than the control group.ConclusionsProviding interventional support could reduce anxiety and depression for women with preterm labour during hospitalization.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2018 ◽  
Vol 9 (2) ◽  
pp. 63
Author(s):  
Anil Kumar Roy ◽  
Nilesh Maruti Gujar ◽  
Arif Ali ◽  
Utpal Borah

Background: Studies have shown that caregivers of the persons with the neurological illness have high levels of psychological distress, depression and caregiver’s burden. The aim of the study was to find out anxiety, depression and caregiver’s burden among the caregivers of persons with neurological illness (PWNI). Method: Thirty caregivers of PWNI attending the Centre of Rehabilitation Sciences, LGB Regional Institute of Mental Health, Tezpur, Assam were selected using purposive sampling technique for the present study. Socio-demographic and clinical data sheet, Zarit Burden Interview Scale and The Hospital Anxiety and Depression Scale were used. Results: The results shown that in Hospital Anxiety and Depression Scale, 26.6% of the caregivers' scores were in the abnormal range in the domain of depression. While in the domain of anxiety, 16.6% scored in the abnormal range. In Zarit Burden of Scale, 13.3% of the caregivers were having little or no burden, 26.6% of the caregivers were having mild to moderate level of burden, 20% were having moderate to severe burden and 30% were having a severe burden of care. Care burden has significant positive correlation with depression (r= .124, p≤ 0.01 and anxiety (r= .124, p≤ 0.05). Conclusion: Caregivers of PWNI have been found to be at higher risk of mental health problems and care burden. The importance of addressing the burden of caregivers involved in the care of PWNI need to be taken into consideration while providing treatment and rehabilitation of PWNI.     Keywords: Anxiety, depression, burden, neurological illness


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