scholarly journals Evaluation of Trace Elements in Thyroid Adenomas Using Energy Dispersive X-Ray Fluorescent Analysis

2021 ◽  
pp. 1-7
Author(s):  
Vladimir Zaichick ◽  
Keyword(s):  
Trace Elements ◽  
Exploratory Study ◽  
Thyroid Tissue ◽  
Energy Dispersive ◽  
Benign Tumors ◽  
Tissue Samples ◽  
X Ray ◽  
Fluorescent Analysis ◽  
Thyroid Adenomas

Thyroid adenomas (TA) are benign tumors, but there is a 20% possibility of malignant transformation. The distinguishing between the TA and thyroid cancer (TC) is tricky, therefore new TA biomarkers are needed. Furthermore, the role of trace elements (TE) in etiology and pathogenesis of TA is unclear. The aim of this exploratory study was to examine the content of bromine (Br), cooper (Cu), iron (Fe), rubidium (Rb), strontium (Sr), and zinc (Zn) in the normal and in adenomatous thyroid. Thyroid tissue levels of six TE were prospectively evaluated in 19 patients with TA and 105 healthy inhabitants. Measurements were performed using 109Cd radionuclide-induced energy-dispersive X-ray fluorescent analysis Tissue samples were divided into two portions. One was used for morphological study while the other was intended for TE analysis. It was found that contents of Br and Cu were significantly higher (25.8 and 4.16 times, respectively) and content of Sr were significantly lower (39%) in adenomatous thyroid in comparison with normal level. There are considerable changes in TE contents in the adenomatous thyroid.

scholarly journals Comparison between Bromine, Calcium, Chlorine, Iodine, Potassium, Magnesium, Manganese, and Sodium Contents in Normal Thyroid and Riedel’s Struma

2021 ◽  
Vol 3 (4) ◽  
pp. 1-6
Author(s):  
Vladimir Zaichick ◽  
Keyword(s):  
Exploratory Study ◽  
Chemical Elements ◽  
Thyroid Tissue ◽  
Control Group ◽  
Healthy Individuals ◽  
Tissue Samples ◽  
Mean Values ◽  
Non Destructive ◽  
Potassium Magnesium

Role of chemical elements (ChE) in etiology and pathogenesis of Riedel’s disease (RD) is unclear. The aim of this exploratory study was to assess whether there were significant changes in thyroid tissue levels of eight ChE (Br, Ca Cl, I, K, Mg, Mn, and Na) are present in the fibrotic transformed thyroid. Eight ChE of thyroid tissue were determined in 6 patients with RD. The control group included thyroid tissue samples from 105 healthy individuals. Measurements were conducted using non-destructive instrumental neutron activation analysis with high-resolution spectrometry of short-lived radionuclides. Reduced mean values of Ca and I content in 6.3 and 6.7 times, respectively, while elevated level of Br in 5.1 times were found in thyroid with RD in comparison with normal level. Because considerable changes in some ChE contents in tissue of thyroid with RD were found, it is reasonable to assume that the levels of these ChE in affected thyroid tissue can be used as RD markers. However, this topic needs additional studies.

scholarly journals Evaluation of Ten Trace Elements in Riedel’s Struma Using Neutron Activation Analysis

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
V Zaichick
Keyword(s):  
Trace Elements ◽  
Neutron Activation Analysis ◽  
Instrumental Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Exploratory Study ◽  
Thyroid Tissue ◽  
Mean Values ◽  
Non Destructive

Aims: Role of trace elements (TE) in etiology and pathogenesis of Riedel’s disease (RD) is unclear. The aim of this exploratory study was to assess whether there were significant changes in thyroid tissue levels of ten TE (Ag, Co, Cr, Fe, Hg, Rb, Sb, Sc, Se, and Zn) are present in the fibrotic transformed thyroid. Methods: Ten TE of thyroid tissue were determined in 6 patients with RD and 105 healthy populations. The measurements were performed using non-destructive instrumental neutron activation analysis with high resolution spectrometry of long-lived radionuclides. Results: Elevated mean values of Rb content were found in thyroid with RD in comparison with normal level. Conclusions: There are considerable changes in Rb content in tissue of thyroid with RD. Thus, it is reasonable to assume that the level of Rb in thyroid tissue can be used as RD markers. However, this topic needs additional studies.

ANALYSIS OF COPPER COINS BY EDXRF TECHNIQUE

2004 ◽  
Vol 14 (03n04) ◽  
pp. 133-139 ◽  
Author(s):  
T. R. RAUTRAY ◽  
V. VIJAYAN ◽  
P. K. NAYAK ◽  
S. JENA
Keyword(s):  
Trace Elements ◽  
Major And Trace Elements ◽  
Spectroscopic Technique ◽  
Energy Dispersive ◽  
Historical Events ◽  
Trade Routes ◽  
X Ray ◽  
Edxrf Technique ◽  
Non Destructive ◽  
Archaeological Objects

Coins are important archaeological objects that can provide useful information regarding preparation methodology and provenance. Their classification plays a fundamental role in dating historical events, in constructing trade routes and in establishing the welfare of population. Several Indian copper coins of different periods have been studied using Energy Dispersive X-ray Fluorescence (EDXRF) spectroscopic technique. The method is rapid, efficient, multi elemental and non-destructive in nature. Concentrations of the major and trace elements like Ca , Ti , V , Cr , Mn , Fe , Co , Ni , Cu , Zn , As and Pb have been estimated in these copper coins. In the present investigation, an attempt has been made to characterize some Indian copper coins of different periods using EDXRF technique.

Simultaneous determination of trace elements in lavage fluids from human bronchial alveoli by energy dispersive x-ray fluorescence. 1: Technique and determination of the normal reference interval.

1985 ◽  
Vol 31 (4) ◽  
pp. 551-555 ◽  
Author(s):  
E A Maier ◽  
F Rastegar ◽  
R Heimburger ◽  
C Ruch ◽  
A Pelletier ◽  
...  
Keyword(s):  
Trace Elements ◽  
Analytical Procedure ◽  
Reference Interval ◽  
Lavage Fluid ◽  
Energy Dispersive ◽  
Polypropylene Film ◽  
Internal Standards ◽  
X Ray ◽  
Large Numbers

Abstract We have applied energy dispersive x-ray fluorescence to the analysis of broncho-alveolar lavage fluids, to determine the concentration of several elements simultaneously with manipulation of the sample minimized. A 20-microL sample of a homogenized lavage fluid, to which two internal standards (containing Y and V) have been added, is deposited on a polypropylene film, 4 microns in thickness, and analyzed by x-ray fluorescence. We report the analytical procedure, the detection limits, and the reproducibility. The normal concentration range for trace elements is reported for a selected population. The simplicity and rapidity of the method, and the possibility of automating measurements, make this procedure suitable for screening large numbers of lavage specimens and to establish the diagnosis of some pneumoconioses.

Simultaneous determination of trace elements in lavage fluids from human bronchial alveoli by energy-dispersive x-ray fluorescence. 3. Routine analysis.

1987 ◽  
Vol 33 (12) ◽  
pp. 2234-2239 ◽  
Author(s):  
E A Maier ◽  
A Dietemann-Molard ◽  
F Rastegar ◽  
R Heimburger ◽  
C Ruch ◽  
...  
Keyword(s):  
Trace Elements ◽  
Occupational Exposure ◽  
Bronchoalveolar Lavage ◽  
Normal Values ◽  
Energy Dispersive ◽  
Fluorescence Technique ◽  
X Ray ◽  
High Concentrations ◽  
Number Of Cells

Abstract We applied the energy-dispersive x-ray fluorescence technique to determination of trace elements in human bronchoalveolar lavage fluids. Our analysis of more than 200 samples allowed us to determine normal reference values, to be used in characterizing occupational exposure. These values are expressed both in nanograms per 1000 cells (of all kinds) and nanograms per 1000 macrophages to correlate lavage efficiency and dust content of the alveoli. The result expressed in milligrams per liter is not sufficient, because some healthy volunteers showed high concentrations of iron but normal values when expressed vs the number of cells. Some examples of abnormal compositions of broncho-alveolar lavages are reported and the fully automated spectrometer developed for clinical and biological investigations is described.

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