scholarly journals Hypoglycemia, an obstacle to achieving glycemic control. Importance of blood glucose self-monitoring

2021 ◽  
Vol 2 (7) ◽  
pp. 40-44
Author(s):  
Inna Urlaeva ◽  
Keyword(s):  
Blood Glucose ◽  
Glycemic Control ◽  
Severe Hypoglycemia ◽  
Fatal Complication ◽  
Self Monitoring ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Blood Glucose Self Monitoring ◽  
Awareness Raising ◽  
Recurrent Hypoglycemia

Hypoglycemia is a well-known factor, limiting the patient's ability to achieve adequate glycemic control, and capable of causing a number of car-diovascular diseases (CVDs). Recurrent hypoglycemia may result in severe, potentially fatal complication of diabetes mellitus (DM), the impaired hypoglycemia awareness, raising the risk of severe hypoglycemia up up to six times. Measuring blood glucose levels is a universally accepted com-ponent of glycemic control and one of the strategies for prevention of hypoglycemia, along with the structured patient education in DM manage-ment and the use of modern hypoglycemic medications. Prevention of severe hypoglycemia may be important for prevention of CVDs in patients with DM.

The role of blood glucose self-monitoring in assessing glycemic variability in patients with type 1 diabetes mellitus

2021 ◽  
Vol 22 (2) ◽  
pp. 152-155
Author(s):  
A. S. Sudnitsyna ◽  
◽  
L. A. Suplotova ◽  
N. V. Romanova ◽  
◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glycemic Variability ◽  
Self Monitoring ◽  
Glucose Levels ◽  
Treatment And Prevention ◽  
Blood Glucose Levels ◽  
Patients With Diabetes ◽  
Blood Glucose Self Monitoring

In the context of the increasing prevalence of diabetes, an important task is to educate the patient on the mandatory self-monitoring of blood glucose levels (SMBG), which is an integral component of the treatment and prevention of acute and chronic complications of the disease. On the basis of the SMBG data, it is possible to assess the parameters of glycemic variability, which is the fluctuations in blood glucose during the day and differences in blood glucose levels at the same time on different days. Due to the fact that GV is one of the main criteria for assessing the quality of glycemic control, its correction is considered as a new goal in the treatment of patients with diabetes.

Self-monitoring of blood glucose levels and glycemic control: the Northern California Kaiser Permanente Diabetes registry∗

2001 ◽  
Vol 111 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Andrew J Karter ◽  
Lynn M Ackerson ◽  
Jeanne A Darbinian ◽  
Ralph B D’Agostino ◽  
Assiamira Ferrara ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glycemic Control ◽  
Northern California ◽  
Kaiser Permanente ◽  
Self Monitoring ◽  
Diabetes Registry ◽  
Glucose Levels ◽  
Blood Glucose Levels

scholarly journals Glucose levels during gestational diabetes pregnancy and the risk of developing postpartum diabetes or prediabetes

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Chadakarn Phaloprakarn ◽  
Siriwan Tangjitgamol
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glycemic Control ◽  
Gestational Diabetes ◽  
Confidence Interval ◽  
Control Group ◽  
Oral Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
The Impact

Abstract Background Blood glucose levels during pregnancy may reflect the severity of insulin secretory defects and/or insulin resistance during gestational diabetes mellitus (GDM) pregnancy. We hypothesized that suboptimal glycemic control in women with GDM could increase the risk of postpartum type 2 diabetes mellitus (T2DM) or prediabetes. Our objective was to evaluate the impact of plasma glucose levels throughout GDM pregnancy on the risk of postpartum T2DM or prediabetes. Methods The medical records of 706 women with GDM who underwent a postpartum 75-g, 2-hour oral glucose tolerance test at our institution between January 2011 and December 2018 were reviewed. These women were classified into 2 groups according to glycemic control during pregnancy: ≤ 1 occasion of either fasting glucose ≥ 95 mg/dL or 2-hour postprandial glucose ≥ 120 mg/dL was defined as optimal glycemic control or else was classified as suboptimal glycemic control. Rates of postpartum T2DM and prediabetes were compared between women with optimal (n = 505) and suboptimal (n = 201) glycemic control. Results The rates of postpartum T2DM and prediabetes were significantly higher in the suboptimal glycemic control group than in the optimal glycemic control group: 22.4% vs. 3.0%, P < 0.001 for T2DM and 45.3% vs. 23.5%, P < 0.001 for prediabetes. In a multivariate analysis, suboptimal glucose control during pregnancy was an independent risk factor for developing either postpartum T2DM or prediabetes. The adjusted odds ratios were 8.4 (95% confidence interval, 3.5–20.3) for T2DM and 3.9 (95% confidence interval, 2.5–6.1) for prediabetes. Conclusion Our findings suggest that blood glucose levels during GDM pregnancy have an impact on the risk of postpartum T2DM and prediabetes.

scholarly journals Transient bilateral diabetic cataracts in a Brazilian Terrier puppy

2005 ◽  
Vol 35 (3) ◽  
pp. 709-712
Author(s):  
Carla de Freitas Campos ◽  
Lilian Stefanoni Ferreira ◽  
Marlos Gonçalves Sousa ◽  
Fernanda Gomes Velasque Gama ◽  
José Luiz Laus ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glycemic Control ◽  
Insulin Therapy ◽  
Lens Opacity ◽  
Human Beings ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
And Control

A case of a Brazilian Terrier puppy presenting diabetic lens opacity that restored transparency after insulin therapy and control of blood glucose levels is reported. This entity has been rarely reported in human beings and has not been reported in dogs before. The rapid glycemic control may have been responsible for the transparency recovery.

scholarly journals Evaluation of prescription pattern and efficacy of anti-diabetic drugs in Coimbatore, India

2017 ◽  
Vol 6 (5) ◽  
pp. 27-33
Author(s):  
Nagarajaperumal Govindasamy ◽  
Mohan Sellappan
Keyword(s):  
Blood Glucose ◽  
Glycemic Control ◽  
Tamil Nadu ◽  
Pharmaceutical Journal ◽  
Scientific Data ◽  
Brand Names ◽  
Prescribing Pattern ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Improving Health Care

In this present study, 1500 Diabetes Mellitus (DM) patients were included from Coimbatore zone, Tamil Nadu, India. The blood glucose levels were monitored to correlate the glycemic control with the antidiabetic drug treatment. This study addressed many variabilities in such treatments including the prescribing pattern of various novel entities along with existing drugs for glycemic control, diabetic vascular complexities on Coimbatore zone, lack of relevant scientific data, occurrences of prescription errors, less awareness of the DM patients, the insufficient number of local hospitals and high cost of the medicine. Data analysis was carried out by segregating the DM patients under study according to their blood glucose level. Results demonstrated that brand names of anti-diabetic drugs were taken more frequently by outpatients when contrasted with inpatients. Also, the number of drugs prescribed under generic names were significantly less than prescribe brand names. Prescribed formulations results indicated that tablets were preferred over other formulations. Frequently prescribed twenty-one brands and their combination results demonstrated the popularity of the insulin human Mixtard® injection 30-40 IU. Moreover, frequently prescribed 21 branded drugs' cost were analyzed. It can be concluded from the current work that appropriate steps should be taken to raise awareness of the DM patients in Coimbatore zone so that they can follow the specialists' instruction for better hyperglycemia control. Finally, it can be suggested that the Tamil Nadu Government should put more effort on improving health care support in Coimbatore zone.Govindasamy and Sellappan, International Current Pharmaceutical Journal, April 2017, 6(5): 27-33http://www.icpjonline.com/documents/Vol6Issue5/01.pdf

Accuracy of Devices for Self-Monitoring of Blood Glucose Including Hypoglycemic Blood Glucose Levels

Diabetes Care ◽  
1995 ◽  
Vol 18 (4) ◽  
pp. 587-588 ◽  
Author(s):  
P. D. Zenob ◽  
A. Keller ◽  
S. E. Jaeggi-Groisman ◽  
Y. Glatz
Keyword(s):  
Blood Glucose ◽  
Self Monitoring ◽  
Glucose Levels ◽  
Blood Glucose Levels

scholarly journals Glucose-Responsive Insulin Through Bioconjugation Approaches

2019 ◽  
Vol 14 (2) ◽  
pp. 198-203 ◽  
Author(s):  
Maria M. Disotuar ◽  
Diao Chen ◽  
Nai-Pin Lin ◽  
Danny Hung-Chieh Chou
Keyword(s):  
Glycemic Control ◽  
Severe Hypoglycemia ◽  
Therapeutic Window ◽  
Insulin Analogs ◽  
Future Directions ◽  
Major Health ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Glucose Responsiveness ◽  
Reduced Risk

Although insulin analogs have markedly improved glycemic control for people with diabetes, glycemic excursions still cause major health problems and complications. In particular, the narrow therapeutic window of current insulin therapy makes it extremely difficult to maintain normoglycemia without risking severe hypoglycemia. Currently, there are no FDA-approved insulin therapeutics whose bioactivity is regulated by blood glucose levels. This review discusses recent progress on developing glucose-responsive insulin (GRI) bioconjugates without the need of exogenous matrices. Through this approach, tremendous efforts have been made over the years to demonstrate the promise of better glycemic control and reduced risk of hypoglycemia. Last, we discuss future directions of GRI development with a goal to maximize the glucose responsiveness.

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