scholarly journals Phthalates consumed from milk: safety assessment for the population

2021 ◽  
Vol 4 (2) ◽  
pp. 85-98
Author(s):  
Zelenkin Sergey Evgen’evich ◽  
Karnazhitskaya Tatyana Dmitrievna ◽  
◽  
Keyword(s):  
Human Health ◽  
Health Research ◽  
Phthalic Acid ◽  
Safety Assessment ◽  
Endocrine System ◽  
Food Product ◽  
Food Products ◽  
Carcinogenic Risk ◽  
Reference Dose ◽  
Research Results

Phthalates, or phthalic acid ethers, are hazardous for human health as they produce negative effects on the endocrine system and liver when entering a body. Alimentary introduction into a body with food products is a priority for phthalates. Phthalates contents in milk are of particular interest since milk is the most popular food product among the population. It is vital to assess whether phthalates consumption from milk is safe for people due to their potential contents in this product and their potential hazards for human health. Research results indicate that when phthalates are introduced with milk it creates unacceptable non-carcinogenic risks for the examined children. Assessment of hazards caused by phthalates introduction allowed revealing that calculated phthalates doses were not safe as per adherence to the reference dose both for children and examined adults. The carcinogenic risk was also estimated as unacceptable both for children and adults.

Allergenomics and analysis of causes of unintentional incorpo‑ ration of substances capable of causing IgE‑mediated food allergy into meat products

2020 ◽  
Vol 5 (3) ◽  
pp. 4-11
Author(s):  
E. V. Kryuchenko ◽  
Yu. A. Kuzlyakina ◽  
V. S. Zamula ◽  
I. M. Chernukha
Keyword(s):  
Food Allergy ◽  
Risk Analysis ◽  
Meat Products ◽  
Food Product ◽  
Food Products ◽  
Legal Regulation ◽  
Comprehensive Assessment ◽  
Ige Mediated

The article discusses the definition and mechanism of IgE‑mediated food allergy, provides an overview of the legal regulation of the production and labeling of allergen-containing food products. In order to prevent the inadvertent appearance of allergens in products during their production, an allergenomics procedure is required — a comprehensive assessment of the allergic potential of a food product: allergenicity of product ingredients, risk analysis, and the procedure for managing allergens in the production.

Policy Considerations for the Design and Use of Web Portals for Researchers, Clinicians, and Patients: A Scoping Literature Review (Preprint)

2020 ◽  
Author(s):  
Michael Lang ◽  
Sébastien Lemieux ◽  
Josée Hébert ◽  
Guy Sauvageau ◽  
Ma'n H. Zawati
Keyword(s):  
Patient Care ◽  
Health Research ◽  
Complex Disease ◽  
Patient Empowerment ◽  
Patient Portals ◽  
Research Results ◽  
Online Systems ◽  
The Public ◽  
Online Tools ◽  
Research Findings

BACKGROUND Medical care and health research are jointly undergoing significant changes brought about by the Internet [1,2,3]. New online tools, apps, and programs are helping to facilitate unprecedented levels of data sharing and collaboration, potentially enabling more precisely targeted treatment and rapid research translation [4,5,6]. Patient portals have been a significant part of this emerging online health ecosystem, providing patients a mechanism for accessing electronic health records, managing appointments and prescriptions, even communicating directly with care providers [7]. Much has been written about the technical and ethical challenges associated with the development and integration of patient portals into the clinic [8,9]. But portal technology might also be used to connect health researchers to clinicians, patients, and the public. Online systems could be a useful platform for broadly and rapidly disseminating research results while also promoting patient empowerment. OBJECTIVE The aim of this study is to assess the potential use of online portals that facilitate the sharing of health research findings among researchers, clinicians, patients, and the public. It will also summarize the potential legal, ethical, and policy implications associated with such tools for public use and in the management of patient care for complex disease. METHODS We systematically consulted three databases, PubMed, Scopus, and WestLaw Next for sources describing online portals for sharing health research findings among clinicians, researchers, and patients and their associated legal, ethical, and policy challenges. raised by the integration of online tools into patient care for complex disease. Of 719 source citations, we retained 22 for review. RESULTS We found a varied and inconsistent treatment of online portals for sharing health research findings among clinicians, researchers, and patients. While the literature supports the view that portals of this kind are potentially highly promising, they remain novel and are not yet being widely adopted. We also found a wide-ranging discussion on the legal, ethical, and policy issues related to the use of online tools for sharing research data. We identified five important policy challenges: privacy & confidentiality, health literacy & patient empowerment, equity, training, and decision making. Each of these, we contend, have meaningful implications for the increased integration of online tools into clinical care. CONCLUSIONS As online tools become increasingly important mechanisms for sharing health research with clinicians, patients, and the public, it is vital that these developments are met with ethical and conceptual scrutiny. Therapeutic portals as they are presented in this paper may become a more widespread feature of precision and translational medicine. Our findings suggest that online portals are already being used to disseminate research results among clinicians, patients, and the public. But much of the ethical and conceptual debate is framed in terms of the patient portal, a concept that does not adequately reflect the potentially broader scope of therapeutic portals. It may be useful to clarify this distinction in future research and to underscore the unique ethical, legal, and policy challenges raised when online systems are used as a platform for disseminating research to as wide an audience as possible. CLINICALTRIAL n/a

Food advertising during children’s television programmes in Italy

2020 ◽  
pp. 1-8
Author(s):  
Silvano Gallus ◽  
Elisa Borroni ◽  
Chiara Stival ◽  
Sharanpreet Kaur ◽  
Sofia Davoli ◽  
...  
Keyword(s):  
Food Product ◽  
Food Products ◽  
Children's Television ◽  
World Health ◽  
Nutritional Values ◽  
International Guidelines ◽  
Food Advertisements ◽  
Health Organization ◽  
Almost All ◽  
The Eu

Abstract Objective: Previous studies from European countries noted that food products promoted on TV for children did not comply with international guidelines, including the World Health Organization European Nutrient Profile Model (WHO-ENPM) and the EU Pledge Nutrition Criteria (EU-PNC, an initiative developed by leading food companies). We aim to provide new data from Italy. Design: Evaluation of Italian TV advertisements. Data on nutritional values for food product advertised were compared with nutritional standards issued by the WHO-ENPM and the EU-PNC. Setting: In total, 180 h of TV programmes from six Italian channels, 2016–2017. Participants: Eight hundred and ten consecutive advertisements during children’s programmes. Results: Out of 810 advertisements, 90 (11·1 %) referred to food products. Among these, 84·5 % of the foods promoted did not meet the WHO-ENPM and 55·6 % the EU-PNC guidelines. Advertisements promoting sweet and salty snacks (i.e. ≥ 70 % of all foods) v. other food products showed higher non-compliance with both the WHO-ENPM (OR: 73·8; 95 % CI: 4·09, 1330) and the EU-PNC (OR: 9·21; 95 % CI: 2·82, 30·1). Conclusions: In Italy, most food advertisements during children’s programmes are not compliant with European nutritional standards. Almost all the advertisements for snacks do not meet international guidelines. As the WHO-ENPM guidelines do not propose standards for all the food products, including meals, there is an urgent need to define independent and easy-to-read guidelines for food advertisements targeting children. As a first step towards the complete ban of food advertisements targeting children recommended by other researchers, these guidelines should be enforced by all the TV broadcasts.

scholarly journals Human Health Risk Distribution and Safety Threshold of Cadmium in Soil of Coal Chemical Industry Area

Minerals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 678
Author(s):  
Kai Zhang ◽  
XiaoNan Li ◽  
ZhenYu Song ◽  
JiaYu Yan ◽  
MengYue Chen ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Health Risk ◽  
Human Health ◽  
Health Risks ◽  
Chemical Industry ◽  
Human Health Risk ◽  
Oral Intake ◽  
Carcinogenic Risk ◽  
Kriging Interpolation Method ◽  
Industry Area

Cadmium (Cd) is a highly carcinogenic metal that plays an important role in the risk management of soil pollution. In this study, 153 soil samples were collected from a coal chemical plant in northwest China, and the human health risks associated with Cd were assessed through multiple exposure pathways. Meanwhile, by the Kriging interpolation method, the spatial distribution and health risks of Cd were explored. The results showed that the average concentration of Cd in the soil was 0.540 mg/kg, which was 4.821 and 5.567 times that of the soil background value in Ningxia and China, respectively. In comparison, the concentration of Cd in the soil was below the national soil environmental quality three-level standard (1.0 mg/kg). In addition, health risk assessment results showed that the total carcinogenic risk of Cd was 1.269 × 10−6–2.189 × 10−6, both above the acceptable criteria (1 × 10−6), while the hazard quotient was within the acceptable level. Oral intake and ingestion of soil particles were the main routes of exposure, and the carcinogenic risk control value of oral intake was the lowest (0.392 mg/kg), which could be selected as the strict reference of the safety threshold for Cd in the coal chemical soil. From Kriging, a prediction map can be centrally predicted on heavy metal pollution in the area surrounding the coal entrance corridor and pedestrian entrance. This study can provide a theoretical basis for the determination of the heavy metal safety threshold of the coal chemical industry in China.

Investigation of the efficiency of beet syrup usage in products based on nutraceutical principles

2021 ◽  
Vol 12 (2) ◽  
Author(s):  
Yu Kryzhova ◽  
◽  
O Deyak ◽  
Keyword(s):  
Risk Factor ◽  
Human Health ◽  
Activity Index ◽  
Sugar Content ◽  
Control Sample ◽  
Food Product ◽  
Experimental Investigations ◽  
Energy Value ◽  
Total Sugar Content ◽  
Healthy Nutrition

The nature of nutrition is the most important factor determining human health. Proper healthy nutrition maintains health, plays an important role in preventing chronic diseases in modern humans. The level of food product quality must meet the human physiological needs for nutrients and energy, and healthy nutrition also includes the concept of the preventive effect of food, or food as a risk factor for chronic non-communicable diseases. When nutrients are in improper proportions, nutrition is considered incorrect, unhealthy, irrational, and may play a role as a risk factor for the development of human diseases. The paper substantiates the use of beet syrup and beet in ketchup technology and the benefits of the developed recipes for human health. It also covers the physicochemical composition of beet syrup, which contains 93.5% dry matter, and sugar composition and content in beet syrup: glucose, fructose, sucrose, and maltose, the total sugar content is 48.8 g/100 g that is 50.2 g/100 g less than common sugar. The ratio of prescription ingredients, established by experimental investigations on organoleptic parameters, is substantiated. The water activity index was investigated, which constituted 0.92 in the second sample, 0.93 – in the first sample, and 0.93 – in the control sample, which will have a positive effect on their shelf life. The examination of the chemical composition showed that the protein content in the first sample increased by 33%, in the second sample – by 56% compared to the control sample; the sugar content reduced by 42.7% in the first sample and by 50.6% in the second sample; the vitamin C content increased; the fiber content increased 3 times; the developed products are enriched with iron, phosphorus, and potassium. The Nutri-score calculation showed that the samples developed according to formulas №1 and №2 belong to categories A and B and are more balanced and beneficial to human health, which indicates the high nutritional value of the products. In terms of the energy value, the developed samples have an advantage over the control. The energy value (kcal/100 g) of the first sample is 100, the second sample – 89.5, and the control sample – 104.

The Ship Domain – A Criterion of Navigational Safety Assessment in an Open Sea Area

2008 ◽  
Vol 62 (1) ◽  
pp. 93-108 ◽  
Author(s):  
Zbigniew Pietrzykowski ◽  
Janusz Uriasz
Keyword(s):  
Artificial Intelligence ◽  
Safety Assessment ◽  
Research Results ◽  
Safe Navigation ◽  
Number Of Factors ◽  
Open Sea ◽  
Sea Area ◽  
Point Of Departure ◽  
Shape And Size

One of the basic tasks in shipping is to ensure safe navigation of vessels. The concept of the ship domain is of major importance in the assessment of a navigational situation and the avoidance of ship collisions. It is difficult to determine a ship domain as its shape and size depend on a number of factors. One question to be answered before the determination of the ship domain is which method to use: statistical, analytic, or expert method using artificial intelligence tools; other questions are connected with domain interpretation. The authors have analyzed the ship domain as a criterion for the assessment of ship navigational safety in an encounter situation in the open sea. The research results are used to answer some of the questions.Part 2 includes definitions of the ship domain and ship fuzzy domain. Part 3, in turn, presents methods of their determination as well as relevant questions. The results of the authors' research, described in Part 4, make up a basis for the determination of the domain and ship fuzzy domain. These have been determined with the so-called dynamic domains as a point of departure. The criteria of ship domain and closest point of approach are compared and discussed. Encounters of various size ships are considered in Part 5. The research and its results are described. Both ship domains and ship fuzzy domains of encountering ships are analyzed. Then, conclusions have been formulated in relation to the effect of the sizes of encountering ships on the shapes and sizes of their domains. Final conclusions are given in Part 6.

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