Analysis of Clinical Test and Quality Control of Pathogenic Bacteria in Patients with Respiratory Tract Infection

Recognition of etiologies of lower respiratory tract infection (LRTI) may help in delivering effective treatment options and circumvent emergence of antibiotic resistance. This study was carried out to uncover bacterial profile and antibiotic sensitivity patterns among 310 LRTI patients attended Rizagary Hospital between January 2014 to December 2016. Standard laboratory techniques were applied in collecting, processing, and culturing sputum and bronchial wash specimens. VITEK® 2 compact systems were used to identify bacteria and their antibiotic sensitivity patterns. Results showed that Streptococcus parasanguinis and Acinetobacter baumannii were the most abundant gram-positive and gram-negative bacteria (GPB & GNB), respectively, isolated from sputum specimens. From bronchial wash specimens, only GNB were detected and Serratia marcescens was the most abundant one. Antibiotic sensitivity tests revealed that Streptococcus parasanguinis was the most resistant GPB and Acinetobacter baumannii was the most resistant GNB. Sputum recovered GPB were highly resistant to Ampicillin, Erythromycin, Levofloxacin, Trimethoprim/Sulfamethoxazole, and Tetracycline. Bronchial wash recovered GNB were highly resistant to Ampicillin, Minocycline, Pefloxacin, Piperacillin, and Ticarcillin. In conclusion, LRTIs are mainly associated with GNB rather than GPB. The recovered Streptococcus parasanguinis and Acinetobacter baumannii were found to be multidrug-resistant pathogens. Ampicillin was ineffective against any of recovered pathogenic bacteria.

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Bacterial causes of upper & lower respiratory tract infection in Sheep

The Iraqi Journal of Veterinary Medicine ◽

10.30539/iraqijvm.v29i1.858 ◽

2005 ◽

Vol 29 (1) ◽

pp. 1-10

Author(s):

Jamal Salman Ali

Keyword(s):

Tract Infection ◽

Respiratory Tract ◽

Nasal Cavity ◽

Respiratory Tract Infection ◽

Lower Respiratory Tract Infection ◽

Lower Respiratory Tract ◽

Pathogenic Bacteria ◽

Bacterial Species ◽

High Sensitivity ◽

Hemorrhagic Lesion

This study was designed to investigate the bacterial species that induceupper and lower respiratory tract infection in sheep, and to find out anyrelationship which may exist between them.Therefore two groups of sheep were employed. The first group wassuffering from certain respiratory signs. While the second group was apparentlyhealthy. Each group included 50 sheep. Research samples were collected for aperiod of six months from AL-Shulla Abattoir.Microbiological investigation indicated the isolation of certainmicroorganisms from all animals in both groups from nasal cavity, and from 34lungs of the first group and 16 lungs of the second group. The number of isolatesfrom the nasal cavity, were 200 from different species ,43 isolates from thebronchioles and 70 from the lungs tissue. On the other hand the number ofbacterial isolates from the nasal cavity, bronchioles and the lung tissue of thefirst group were 113, 29 and 55 respectively.The study revealed the isolation of potentially pathogenic bacteria from thelower respiratory system of both groups, these bacteria were namely Pasteurellahaemolytica of serotype (A2), Niesseria spp. and Corynebacterium pyogenes,the number of isolates were 6 for each, and 8 isolates of Staphylococcus aureus.These bacteria were also isolated from the nasal cavity. The isolation of thesebacteria from the nasal strongly suggested their presence in the lungs and theprobable role in lesion formation.Animal inoculation were performed to study the virulence of P.haemolytica which caused certain hemorrhagic lesion in the lung , liver andkidney, with areas of necrosis in the lungs of the experimentally inoculatedrabbit, and caused death in mice. While the inoculation of C. ovis caused thedeath of rabbits within 72 hours, together with the presence of multipleabscessation on the internal organs and abdomenal wall.Sensitivity tests indicated a high sensitivity of most isolates to Gentamicin,Erythromycin and Kanamycin.

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Pathogenic Bacteria and Drug Sensitivity Analysis of Lower Respiratory Tract Infections in Patients

Advanced Emergency Medicine ◽

10.18686/aem.v3i1.2 ◽

2014 ◽

Vol 3 ◽

pp. 4

Author(s):

Qianqian Wang ◽

Chuanhui Wang

Keyword(s):

Internal Medicine ◽

Drug Resistance ◽

Tract Infection ◽

Respiratory Tract ◽

Respiratory Tract Infection ◽

Lower Respiratory Tract Infection ◽

Lower Respiratory Tract ◽

Pathogenic Bacteria ◽

Gram Negative Bacteria ◽

Gram Negative

Objective: To study drug resistance of pathogenic bacteria in lower respiratory tract infection in patients in Respiratory Department of Internal Medicine. Method: On October 2011 to October 2013, there were 112 patients with lower respiratory tract infection in the hospital respiratory medicine ward were reviewed for analysis by collected patient’s infected blood, urine and sputum for laboratory analysis and investigation of drug resistance. Results: In a total of 112 strains of pathogenic bacteria, gram negative bacteria, the number of strains was 68, accounting for 60.7% of all strains. The analysis of gram positive bacteria had the lowest drug resistance to vancomycin, but the resistance to erythromycin and penicillin was the highest, while gram negative bacteria were the lowest, but the drug resistance was high. Conclusion: In Respiratory Department Of Internal Medicine, patients with lower respiratory tract infection, the pathogenic bacteria which is gram negative bacterial infection is more common, to clarify the distribution of the infection of pathogenic bacteria, and the drug resistance to do a good grasp of the lower respiratory tract infection in patients with lower respiratory tract infection in patients with the role of a thing.

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