scholarly journals A Clinical Evaluation of Biphasic Calcium Phosphate Alloplast with and without a Flowable Bioabsorbable Guided Tissue Regeneration Barrier in the Treatment of Mandibular Molar Class II Furcation Defects

2016 ◽  
Vol 17 (2) ◽  
pp. 143-148 ◽  
Author(s):  
Vineet Kini ◽  
Dilip G Nayak ◽  
Ashita S Uppoor
Keyword(s):  
Calcium Phosphate ◽  
Tissue Regeneration ◽  
Biphasic Calcium Phosphate ◽  
Class Ii ◽  
Bone Replacement ◽  
Group I ◽  
Furcation Defects ◽  
Mandibular Molar ◽  
Group Ii ◽  
Bone Replacement Graft

ABSTRACT Background Guided tissue regeneration (GTR) therapy has shown good results in the management of mandibular molar class II furcation defects. Advances in biomaterial sciences have developed alloplastic bone replacement graft materials and bioabsorbable GTR barrier membranes with good biologic response and handling properties. The aim of this study was to compare the attachment gain and the bone fill obtained with an alloplast [biphasic calcium phosphate (BCP) 60% hydroxyapatite (HA) and 40% beta tricalcium phosphate (β-TCP)] with and without a bioabsorbable GTR barrier [flowable poly (DL-lactide) (PLA) dissolved in N-methyl-2- pyrrolidone (NMP)] in the treatment of mandibular molar class II furcation defects. Materials and methods A total of 20 class II furcation defects were treated in 16 patients with chronic periodontitis in a comparative study. Ten defects were treated with Camceram® (BCP 60% HA and 40% – TCP) bone replacement graft material (group I) and 10 defects with a combination of Camceram® bone replacement graft material with Atrisorb® Freeflow™, bio-absorbable GTR barrier (flowable PLA dissolved in NMP) (group II). At baseline and at 6 months postsurgery, clinical parameters of vertical probing depth (PD) and horizontal probing depth (P-H), clinical attachment level (CAL), gingival recession (GR), and vertical depth of furcation defect (VDF) and horizontal depth of furcation defect (BP-H) were evaluated. Results Statistical analysis was done with the Statistical Package for Social Sciences (SPSS) program. Intergroup comparisons made at 6 months postsurgery by unpaired Student's t-test showed mean reduction in PD in group I was 3.10 ± 0.73 mm and in group II was 3.20 ± 1.03 mm (p > 0.05). Mean reduction in P-H in group I was 1.60 ± 0.69 mm and in group II was 1.90 ± 0.73 mm (p > 0.05). Gain in CAL in group I was 2.80 ± 1.03 mm and in group II was 2.90 ± 0.94 mm (p > 0.05). Change in GR in group I was .0.30 ± 0.48 mm and in group II was .0.30 ± 0.48 (p > 0.05). Reduction in VDF in group I was 1.30 ± 0.67 mm and in group II was 1.80 ± 0.63 mm (p . 0.01). Reduction in BP-H in group I was 1.30 ± 0.67 mm and in group II was 1.90 ± 0.73 mm (p . 0.05). Conclusion It was concluded that the combination technique of BCP alloplast with a flowable bioabsorbable GTR barrier led to better results in regard to defect bone fill as compared with when the BCP alloplast alone was used. How to cite this article Kini V, Nayak DG, Uppoor AS. A Clinical Evaluation of Biphasic Calcium Phosphate Alloplast with and without a Flowable Bioabsorbable Guided Tissue Regeneration Barrier in the Treatment of Mandibular Molar Class II Furcation Defects. J Contemp Dent Pract 2016;17(2):143-148.

scholarly journals A Clinical Evaluation of Anorganic Bovine Bone Graft Plus 10% Collagen with or without a Barrier in the Treatment of Class II Furcation Defects

2006 ◽  
Vol 7 (1) ◽  
pp. 60-70 ◽  
Author(s):  
Krishnanjaneya Pathakota Reddy ◽  
Dilip Gopinath Nayak ◽  
Ashita Sadananda Uppoor A
Keyword(s):  
Bone Graft ◽  
Gingival Recession ◽  
Class Ii ◽  
Bovine Bone ◽  
Hard Tissue ◽  
Barrier Membranes ◽  
Group I ◽  
Probing Depth ◽  
Furcation Defects ◽  
Group Ii

Abstract The use of bone replacement grafts with barrier membranes in class II furcation defects are aimed at improving the outcome of the regenerative technique. In this regard, however, there is a paucity of studies comparing the results obtained with bone grafts alone or in combination with barrier membranes. The aim of this study was to clinically compare an anorganic bovine bone graft plus 10% collagen (BO) with or without a bioresorbable collagen barrier (BG) in human mandibular molar class II furcation defects. Methods and Materials Twenty mandibular class II furcation defects (ten patients with bilateral defects) were treated either with BO (group I) or a combination of BO/BG (group II). Each defect was randomly assigned to either group I or group II. The soft tissue and hard tissue measurements including vertical probing depth (VPD), horizontal probing depth (HPD), clinical attachment level (CAL), gingival recession (GR), vertical depth of furcation defect (VDF), and horizontal depth of furcation defect (HDF) were recorded at baseline and six months after surgery. Results Both treatment procedures resulted in statistically significant reduction in VPD and HPD, gain in CAL, and reduction in VDF and HDF. There was a statistically significant difference between group I and group II in all soft and hard tissue parameters with the exception of VPD reduction and gingival recession. Conclusion The findings of this study suggest superior clinical results with BO/BG treatment when compared to BO treatment in mandibular class II furcation defects. Citation Reddy KP, Nayak DG, Uppoor A AS. A Clinical Evaluation of Anorganic Bovine Bone Graft Plus 10% Collagen with or without a Barrier in the Treatment of Class II Furcation Defects. J Contemp Dent Pract 2006 February;(7)1:060-070.

Guided Tissue Regeneration in Human Class II Furcation Defects Using a Diphenylphosphorylazide-Cross-Linked Collagen Membrane: A Consecutive Case Series

2003 ◽  
Vol 74 (7) ◽  
pp. 1071-1079 ◽  
Author(s):  
Charles S. Zahedi ◽  
S. Asghar Miremadi ◽  
Gérard Brunel ◽  
Eric Rompen ◽  
Jean-Pierre Bernard ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Case Series ◽  
Class Ii ◽  
Guided Tissue Regeneration ◽  
Collagen Membrane ◽  
Consecutive Case ◽  
Human Class ◽  
Furcation Defects

scholarly journals Socket preservation by beta-tri-calcium phosphate with collagen compared to platelet-rich fibrin: A clinico-radiographic study

2016 ◽  
Vol 10 (02) ◽  
pp. 264-276 ◽  
Author(s):  
Swati Das ◽  
Rajesh Jhingran ◽  
Vivek Kumar Bains ◽  
Rohit Madan ◽  
Ruchi Srivastava ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Cost Effective ◽  
Cortical Plate ◽  
Socket Preservation ◽  
Platelet Rich Fibrin ◽  
Tissue Replacement ◽  
Group I ◽  
The Mean ◽  
Group Ii ◽  
Insight Into

ABSTRACT Objectives: This study was primarily designed to determine the clinico-radiographic efficacy of platelet-rich fibrin (PRF) and beta-tri-calcium phosphate with collagen (β-TCP-Cl) in preserving extraction sockets. Materials and Methods: For Group I (PRF), residual sockets (n = 15) were filled with autologous PRF obtained from patients’ blood; and for Group II (β-TCP-Cl), residual sockets (n = 15) were filled with β-TCP-Cl. For the sockets randomly selected for Group II (β-TCP-Cl), the reshaped Resorbable Tissue Replacement cone was inserted into the socket. Results: Clinically, there was a significantly greater decrease in relative socket depth, but apposition in midcrestal height in Group II (β-TCP-Cl) as compared to Group I (PRF), whereas more decrease in buccolingual width of Group I (PRF) than Group II (β-TCP-Cl) after 6 months. Radiographically, the mean difference in socket height, residual ridge, and width (coronal, middle, and apical third of socket) after 6 months was higher in Group I (PRF) as compared to Group II (β-TCP-Cl). The mean density (in Hounsfield Units) at coronal, middle, and apical third of socket was higher in Group I (PRF) as compared to Group II (β-TCP-Cl). There were statistically significant apposition and resorption for Group I (PRF) whereas nonsignificant resorption and significant apposition for Group II (β-TCP-Cl) in buccal and lingual/palatal cortical plate, respectively, at 6 months on computerized tomography scan. Conclusion: The use of either autologous PRF or β-TCP-Cl was effective in socket preservation. Results obtained from PRF were almost similar to β-TCP-Cl; therefore being autologous, nonimmune, cost-effective, easily procurable regenerative biomaterial, PRF proves to be an insight into the future biofuel for regeneration.

scholarly journals Sex specificities of medical and social parameters in patients with coronary artery disease with different severity of depression

2021 ◽  
Vol 20 (1) ◽  
pp. 2425
Author(s):  
Yu. V. Nagibina ◽  
M. I. Kubareva ◽  
D. S. Knyazeva
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Class Ii ◽  
Mental Condition ◽  
Class Iii ◽  
Group I ◽  
Severity Of Depression ◽  
The Mean ◽  
Group Ii ◽  
Artery Disease

Aim. To determine the sex specificities of medical and social parameters in patients hospitalized due to coronary artery disease (CAD), class II, III, IV angina, aged 35-60 years and assess the significance of their relationship with different levels of depression.Material and methods. The study involved 312 patients aged 35-60 with documented CAD, class II, III, IV angina. Two comparison groups were identified: group I — 138 patients (men, 81; women, 57) with CAD and without depression (mean age, 47,8±4,6 years); group II — 174 patients (men, 60; women, 105) with CAD and depression (mean age, 48,3±5,3 years). Medical and social data, the severity of depression and distress tolerance, psychological status and quality of life was assessed. Statistical analysis was carried out, which are presented as the mean and standard error of the mean (M±m). The odds ratio (OR) and 95% confidence interval (CI) were calculated. Differences were considered significant at p<0,05.Results. The prevalence of depression among patients with CAD was 55,77%, while women were 1,5 times more likely to suffer it than men. Depression was significantly associated with hyperglycemia, hypercholesterolemia, and class III-IV angina, regardless of sex. Class III and IV angina prevailed in women, while class II angina — in men (OR, 2,16; 95% CI, 1,37-3,41, p<0,001)). Women were more prone to degree II-III disability (group II, 26,67%; group I 8,77%; p=0,008), compared with men (group II, 27,54%; group I, 11,11%; p=0,012). Sedentary lifestyle was also associated to a greater extent with the female sex than with the male (OR, 2,89, 95% CI, 1,46-5,70, p=0,003; OR, 2,31, 95% CI, 1,19-4,48; p=0,014, respectively). Both men and women showed a significant association of depression with atherosclerosis (p<0,001), however, sex differences did not reach significance. Indicators such as lack of job and higher education, as well as smoking and arrhythmias were characteristic of both sexes, but had a greater impact on the mental condition of men (p=0,002, p<0,001, p=0,0014 and p=0,01, respectively). For men, the relationship of depression with diabetes (8,7 vs 0%; p=0,008), obesity (42,03 vs 19,75%; p=0,004), subordinate status (82,61 vs 64,2%; p=0,016) and unmarried status (60,87 vs 40,74%; p=0,02).Conclusion. There are significant differences in factors contributing to depression in different sex groups. The association of depression with CAD has an adverse effect on the physical and psychological health of both males and females. At the same time, women are more prone to mental disorders than men. It is necessary to further study the sex characteristics of medical and social parameters in order to personalize treatment methods.

Comparison of AdvanSync2® and Twin Block Appliances in Treatment of Class II Malocclusion With Retrognathic Mandible—An Observational Retrospective Study

2021 ◽  
pp. 030157422110572
Author(s):  
Ankit Kumar Shahi ◽  
Payal Sharma ◽  
Achint Juneja ◽  
Divya Shetty ◽  
Rishibha Bhardwaj ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Class Ii ◽  
T Test ◽  
Growth Spurt ◽  
Class Ii Malocclusion ◽  
Twin Block ◽  
Group I ◽  
Tissue Changes ◽  
Group Ii ◽  
Soft Tissue Changes

Objectives: To evaluate the treatment outcomes between Twin Block and AdvanSync2® appliances by comparing the skeletal, dentoalveolar, and soft tissue changes. Materials and Methods: Radiographic data of 20 patients were retrospectively analyzed. Data were selected from patients in their skeletal growth spurt as evaluated by the cervical vertebral maturation method (CVMI 2, 3, and 4), with class II malocclusion characterized with retrognathic mandible (ANB > 4°, SNB < 77°, FMA = 25 ± 5°, overjet > 5 mm). There were 10 patients in each group that underwent orthodontic correction for class II malocclusion: either using Twin Block or AdvanSync2®. Independent t test and Paired t test and chi-square tests were used for the data analysis. The level of statistical significance was set at P value ≤.05. Results: The chronological and skeletal age were similar in both the groups. Records were taken for the functional treatment with mean treatment span of 8 ± 1 month. Changes in SNB (group I = 1.59°, group II = 3.11°) ( P < .01), Co-Gn (group I = 2.89 mm, group II = 5.34 mm), and U1-L1° (group I = −1.51°, group II = 2.97°) showed statistically different outcome between the groups, when the pre-post data were studied. Rest of the variables—cranial base, maxillary skeletal, mandibular skeletal, intermaxillary, vertical skeletal, maxillary dentoalveolar, mandibular dentoalveolar, and soft tissue—showed similar outcome ( P > .05). Conclusion: Both appliances lead to desirable outcomes in the correction of class II malocclusion. AdvanSync2® resulted in inducing more of changes in SNB and effective mandibular length as compared to Twin Block. Overjet and molar relation improved significantly with both the appliances. Both the appliances resulted in similar skeletal, dentoalveolar, and soft tissue changes.

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