scholarly journals Botulinum Toxin for the Treatment of Gummy Smile

2017 ◽  
Vol 18 (6) ◽  
pp. 474-478 ◽  
Author(s):  
Afnan F Al-Fouzan ◽  
Lamia S Mokeem ◽  
Reem T Al-Saqat ◽  
Maisa A Alfalah ◽  
Mana A Alharbi ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Neuromuscular Disorders ◽  
Type I ◽  
Lower Margin ◽  
Female Patients ◽  
Dermatology Clinic ◽  
Before And After ◽  
The Mean ◽  
Gummy Smile

ABSTRACT Aim The aim was to evaluate the effect of botulinum toxin (Botox) injections as a conservative treatment for gummy smile. Materials and methods An experimental in vivo study was conducted at a dermatology clinic in Riyadh in January 2016. The study included 23 female patients who ranged from 20 to 50 years and were treated with Botox injections due to excessive maxillary gingival display. The patients with short clinical crowns or long maxilla, those who were pregnant or breastfeeding, and patients with neuromuscular disorders were excluded. Patients received Botox type I, injected 3 mm lateral to the alar-fascial groove at the level of the nostril opening at the insertion of the levator labii superioris alaeque nasi muscle. Photos were taken of the patient's smile before and after the treatment and were then uploaded to the SketchUp program to calculate improvements in gingival display. The distance from the lower margin of the upper lip to the gingival margin was calculated pre- and posttreatment. The amount of improvement was calculated as (pre-Botox treatment – post-Botox treatment/pre-Botox treatment × 100). The mean percentage of the total improvement was analyzed. Results A total of 23 female patients received treatment to improve their gummy smile. Improvement was clear 2 weeks after Botox injection. The mean percentage of improvement in the gingival display was 99.6%. Conclusion Botox type I is an effective conservative technique to improve gummy smile caused by muscular hyperfunction. Clinical significance Patients’ retention highly indicated that they were satisfied with the provided treatment by Botox injections. Improving the quality of life with least painful experience and immediate results was the major advantage for Botox type I. How to cite this article Al-Fouzan AF, Mokeem LS, Al-Saqat RT, Alfalah MA, Alharbi MA, Al-Samary AE. Botulinum Toxin for the Treatment of Gummy Smile. J Contemp Dent Pract 2017;18(6):474-478.

Evaluation of Changes in Depression Levels of Bruxism Patients Treated With Botulinum Toxin-A

2021 ◽  
pp. 232020682110065
Author(s):  
Deniz Erdil ◽  
Nilsun Bagis ◽  
Hakan Eren ◽  
Melike Camgoz ◽  
Kaan Orhan
Keyword(s):  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Age Groups ◽  
Treatment Method ◽  
Definitive Treatment ◽  
Toxin A ◽  
Physiological Factors ◽  
Before And After ◽  
The Mean ◽  
Post Hoc

Aim: Bruxism is defined as the involuntary recurrent masticatory muscle activity characterized by gnashing, grinding, clenching of teeth, and/or pushing the mandible. Factors creating its etiology are peripheral (morphological) or central (physiopathological and physiological), and exogenous. Recently, among physiological factors, depression and bruxism were considered to be related. A definitive treatment method does not exist for bruxism; however, botulinum toxin-A (BT-A) application is an up-to-date and effective way of treatment. The present study is aimed to evaluate the levels of depression in bruxism patients treated with BT-A application. Materials and Methods: A total of 25 individuals (23 females and 2 males) who were diagnosed as bruxism patients were included in the study. 25 U of BT-A for each masseter muscle was injected into the patients. Patients were prospectively observed for a possible change in depression levels by using Beck’s Depression Inventory. The inventory was implemented before and six months after the BT-A application. Depression levels before and six months after the injection were compared. A paired t-test was used to compare “before” and “after” treatment values. One-way analysis of variance and post-hoc Tukey tests were used to evaluate the change in Beck’s Depression Inventory scores according to age groups. Results: The mean total score was 7.80 ± 8.10 before the treatment and 7.16 ± 6.52 six months after the treatment. The decrease in the mean score was not statistically significant ( P > .05). Conclusion: In conclusion, despite the decrease in the mean Beck’s Depression Inventory scores, a statistically significant decrease in the depression levels of patients was not observed.

scholarly journals Pre- and intraoperative acoustic and functional assessment of the novel APrevent® VOIS implant during routine medialization thyroplasty

2019 ◽  
Vol 277 (3) ◽  
pp. 809-817
Author(s):  
Guan-Yuh Ho ◽  
Matthias Leonhard ◽  
Doris-Maria Denk-Linnert ◽  
Berit Schneider-Stickler
Keyword(s):  
Vocal Fold ◽  
Type I ◽  
The Novel ◽  
Glottal Closure ◽  
Medialization Thyroplasty ◽  
Before And After ◽  
Glottal Insufficiency ◽  
The Mean ◽  
Acoustic Analyses ◽  
Short Time

Abstract Purpose Persistent unilateral vocal fold paralysis (UFVP) with glottal insufficiency often requires type I medialization thyroplasty (MT). Previous implants cannot be adjusted postoperatively if necessary. The newly developed APrevent® VOIS implant (VOIS) can provide postoperative re-adjustment to avoid revision MT. The objective of this pilot study is to evaluate the VOIS intraoperatively concerning voice improvement, surgical feasibility and device handling. Methods During routine MT, VOIS was applied short time in eight patients before the regular implantation of the Titanium Vocal Fold Medialization Implant (TVFMI™). In all patients, perceptual voice sound analysis using R(oughness)–B(reathiness)–H(oarseness)-scale, measurement of M(aximum)–P(honation)–T(ime) and glottal closure in videolaryngoscopy were performed before and after implanting VOIS/TVFMI™. Acoustic analyses of voice recordings were performed using freeware praat. Surgical feasibility, operative handling and device fitting of VOIS and TVFMI™ were assessed by the surgeon using V(isual)-A(nalog)-S(cale). Data were statistically analyzed with paired t test. Result All patients showed significant improvement of voice sound parameters after VOIS/TVFMI™ implantation. The mean RBH-scale improved from preoperative R = 2.1, B = 2.3, H = 2.5 to R = 0.6, B = 0.3, H = 0.8 after VOIS and R = 0.5, B = 0.3, H = 0.8 after TVFMI™ implantation. The mean MPT increased from preoperative 7.9 to 14.6 s after VOIS and 13.8 s after TVFMI™ implantation. VOIS/TVFMI™ achieved complete glottal closure in 7/8 patients. The satisfaction with intraoperative device fitting and device handling of VOIS was as good as that of TVFMI™. Conclusion The novel APrevent® VOIS implant showed similar intraoperative voice improvement compared to routinely used TVFMI™ without adverse device events and with safe device fitting.

Effect of Honey and Green Tea Solutions on Streptococcus mutans

2015 ◽  
Vol 39 (5) ◽  
pp. 435-441
Author(s):  
F Abdelmegid ◽  
M Al-Agamy ◽  
A Alwohaibi ◽  
H Ka'abi ◽  
F Salama
Keyword(s):  
Streptococcus Mutans ◽  
Green Tea ◽  
Saliva Sample ◽  
Post Intervention ◽  
Cross Sectional ◽  
Colony Forming Unit ◽  
Before And After ◽  
The Mean ◽  
Mouth Rinsing

Objectives: The aim of this cross-sectional in vivo study was to assess the effect of green tea and honey solutions on the level of salivary Streptococcus mutans. Study design: A convenient sample of 30 Saudi boys aged 7–10 years were randomly assigned into 2 groups of 15 each. Saliva sample was collected for analysis of level of S. mutans before rinsing. Commercial honey and green tea were prepared for use and each child was asked to rinse for two minutes using 10 mL of the prepared honey or green tea solutions according to their group. Saliva samples were collected again after rinsing. The collected saliva samples were prepared and colony forming unit (CFU) of S. mutans per mL of saliva was calculated. Results: The mean number of S. mutans before and after rinsing with honey and green tea solutions were 2.28* 108(2.622*108), 5.64 *107(1.03*108), 1.17*109(2.012*109) and 2.59*108 (3.668*108) respectively. A statistically significant reduction in the average number of S. mutans at baseline and post intervention in the children who were assigned to the honey (P=0.001) and green tea (P=0.001) groups was found. Conclusions: A single time mouth rinsing with honey and green tea solutions for two minutes effectively reduced the number of salivary S. mutans of 7–10 years old boys.

Ultrasonographic Bioinformatics Analysis of Uterus After Myomectomy

2020 ◽  
Vol 10 (6) ◽  
pp. 1374-1378
Author(s):  
Lili Jiang ◽  
Chuanxin Cheng ◽  
Xinmei Sheng
Keyword(s):  
Blood Flow ◽  
Bioinformatics Analysis ◽  
Uterine Wall ◽  
Before And After ◽  
The Mean

Objective: The myomectomy will affect the shape of uterine wall. Ultrasound can analyze the bioinformatics characteristics of uterus such as shape and blood flow in vivo. The aim of this study is to analyze the ultrasonographic bioinformatics of uterus after myomectomy. Methods: A total of 127 patients underwent myomectomy were examined by ultrasonography before operation, and 7 d, 1 m, 3 m, and 6 m after operation. The changes of uterine echo and blood signals were observed and recorded. Results: The mean volume of uterus was (152 ± 64) cm3 before myomectomy. During 6 m after operation, the uterus volume in all patients was decreased gradually. At 7 d and 1 m after operation, the mean volume of uterus was (73 ± 22) cm3 and (54 ± 23) cm3, respectively (about 48% and 36% of volume before operation). Different degree of scar echo appeared in 43 patients (33.8%). The diameter of scars was decreased remarkably during 6 months after myomectomy, especially 1 month after operation. Conclusion: The bioinformatics characteristics of uterus changed obviously before and after myomectomy. Ultrasonography is useful to evaluate these changed.

scholarly journals In vivo exposure for fear of pain and avoidance of movement in low back pain

2020 ◽  
Vol 73 (5) ◽  
Author(s):  
Érica Brandão de Moraes ◽  
Francisco Farias Martins Júnior ◽  
Cibele Andrucioli de Mattos-Pimenta
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Daily Living ◽  
Low Back ◽  
Fear Of Pain ◽  
Before And After ◽  
Quasi Experimental ◽  
The Mean ◽  
Fear And Anxiety

ABSTRACT Objectives: to verify the effects of hierarchization and in vivo exposure for fear of pain, avoidance of movement, and anxiety in chronic low back pain. Methods: quasi-experimental study. The 27 patients who participated graded the damage associated with the movements in each of the 40 activities of daily living depicted in pictures using a scale from 0 to 100. The patients chose five out of all the activities that received a score higher than 50 to carry out the exposure. The intensities of fear and anxiety were measured before and after each exposure session. Results: the frequencies of the gender were equal, and the mean age was 44.9 years. The activities chosen more frequently for the exposure were shoveling (33.3%) and running (33.3%). There was reduction of fear and anxiety before and after exposure (p<0.001). Conclusions: hierarchization and in vivo exposure were effective in reducing fear and anxiety.

scholarly journals Microtubules in cone myoid elongation in the teleost retina.

1978 ◽  
Vol 78 (1) ◽  
pp. 247-259 ◽  
Author(s):  
R H Warren ◽  
B Brunside
Keyword(s):  
Serial Section ◽  
Dark Adaptation ◽  
Cone Cells ◽  
Before And After ◽  
Teleost Retina ◽  
The Mean ◽  
Retinal Cone

The myoids of retinal cone cells of the blue-striped grunt (Haemulon sciurus) undergo significant elongation during dark adaptation of the retina. Longitudinally oriented microtubules are present in myoids both before and after elongation. Injection of colchicine into the vitreous of the eye in vivo disrupts the microtubules in the myoids and prevents dark-adaptive myoid elongation. Counts of microtubules in transverse sections along the lengths of elongating myoids show that there is a uniform decrease in the number of microtubules at any one point along the myoid as the myoid elongates. The magnitude of the decrease is proportional to the extent of the elogation. The product of the mean myoid microtubule number (determined from counts at progressive intervals along the myoid) and the myoid length remains essentially constant during myoid elongation, indicating that the total quantity of microtubules in the myoid does not increase with elogation. Serial section tracings of the microtubules along the myoids suggest that individual microtubules do not extend the length of the myoid and that the myoid microtubular apparatus consists of bundles of overlapping shorter microtubules. We propose that elongation of the myoid is accompanied by sliding redistribution of microtubules along the length of the myoid, and that the sliding may be generated by interaction between microtubules in regions where they closely overlap in bundles. We find no evidence for the involvement of discrete, electron-dense microtubular organizing centers in myoid elogation.

Cervical spinal motion before and after surgery in patients with Chiari malformation Type I associated with syringomyelia

2007 ◽  
Vol 7 (5) ◽  
pp. 473-477 ◽  
Author(s):  
Atsushi Ono ◽  
Futoshi Suetsuna ◽  
Kazumasa Ueyama ◽  
Toru Yokoyama ◽  
Shuichi Aburakawa ◽  
...  
Keyword(s):  
Foramen Magnum ◽  
Type I ◽  
Foramen Magnum Decompression ◽  
Chiari Malformation Type I ◽  
Spinal Motion ◽  
Flexion Extension ◽  
Before And After ◽  
The Mean ◽  
The Relationship ◽  
Tonsillar Descent

Object There have been few reports about the cervical spinal motion in patients with Chiari malformation Type I (CM-I) associated with syringomyelia. To investigate this phenomenon, the relationship between the preoperative cervical range of motion (ROM) and the stage of cerebellar tonsillar descent as well as the cervical ROM before and after foramen magnum decompression (FMD) were evaluated. Methods Thirty patients who had CM-I associated with syringomyelia and who underwent FMD participated in the study. The ROM and lordosis angle of the cervical spine were measured on x-ray films. In addition, the relationship between preoperative degree of cerebellar tonsillar descent and the ROM between the levels of the occiput (Oc) and C2 was investigated. Results The mean flexion–extension ROM at Oc–C2 was 15.5° before and 14.1° after surgery, and the mean flexion–extension ROM of C2–7 was 55.1° before and 52.8° after surgery. The mean pre- and postoperative lordosis angles at C2–7 were 16.8 and 19.1°, respectively. There was no significant difference between the values measured before and after surgery. There was no correlation between the degree of cerebellar tonsillar descent and the ROM at Oc–C2. Conclusions Foramen magnum decompression is an excellent surgical technique that has no effect on the postoperative cervical ROM and cervical alignment.

scholarly journals Clinical and electromyographic evaluation of botulinum toxin type A in the treatment of gummy smile: A prospective clinical study

2021 ◽  
Vol 15 (2) ◽  
pp. 122-128
Author(s):  
Payal Padmakar Mate ◽  
Kumar Nilesh ◽  
Anand Joshi ◽  
Arun Panda
Keyword(s):  
Botulinum Toxin ◽  
Clinical Study ◽  
Repeated Measures ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Prospective Clinical Study ◽  
Upper Lip ◽  
The Mean ◽  
Gummy Smile

Background. The present study aimed to assess the effect of botulinum toxin type A (BTX-A) for the management of gummy smile and evaluate its stability after administrating BTX-A clinically and using electromyography. Methods. The investigators designed and implemented a prospective clinical study on 10 patients with a gummy smile. Patients with different types of gummy smile were injected with BTX-A in the levator muscles of the upper lip and were followed for six months. The effect of BTX-A was evaluated clinically and using electromyography preoperatively and after two weeks and three and six months. Statistical analyses were carried out using repeated measures ANOVA and post hoc Bonferroni tests for pairwise comparisons. Results. The sample consisted of 10 patients with an anterior gummy smile (n=3), posterior gummy smile (n=2), mixed gummy smile (n=3), and asymmetrical gummy smile (n=2). There were significant differences (P<0.001) between the mean gingival display and compound muscle action potential at two-weeks and three-month follow-ups. The maximum result was obtained at the two-week interval. The mean gingival display and C-MAP values increased slightly at the three-month postoperative interval and gradually increased to the baseline values at six-month follow-up. Conclusion. BTX-A is an effective, minimally invasive, and temporary treatment modality for gummy smiles. The electromyographic study is a convenient method for assessing changes in the upper lip muscle contractility to quantify the effect of BTX-A in the treatment of gummy smile.

scholarly journals Botulinum Toxin A Facilitated Laparoscopic Repair of Complex Ventral Hernia

2022 ◽  
Vol 8 ◽  
Author(s):  
Fu-Xin Tang ◽  
Ning Ma ◽  
Enmin Huang ◽  
Tao Ma ◽  
Chuang-Xiong Liu ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Hernia Repair ◽  
Ventral Hernia ◽  
Botulinum Toxin A ◽  
Abdominal Muscles ◽  
Toxin A ◽  
Complex Ventral Hernia ◽  
Combined Use ◽  
Before And After ◽  
The Mean

Background: Complex ventral hernia repair can be challenging despite the recent advances in surgical techniques. Here, we aimed to examine the effectiveness of preoperative combined use of botulinum toxin A (BTA) and preoperative progressive pneumoperitoneum (PPP) for surgical preparation of patients with complex ventral hernia.Methods: In this prospective, observational study, we included 22 patients with complex ventral hernia between January 2018 and May 2021. All patients were treated with BTA injections into the lateral abdominal muscles and PPP before hernia repair. The lengths of abdominal wall muscles, the volumes of the incisional hernia (VIH), the volumes of the abdominal cavity (VAC), and the VIH/VAC ratio were measured before and after BTA and PPP using abdominal CT scan. All Hernias were repaired using laparoscopic intra-peritoneal onlay mesh (IPOM) or laparoscopic-open-laparoscopic (LOL) techniques.Results: Imaging showed a significant increase in the mean lateral abdominal muscle length from 13.1 to 17.2 cm/side (p &lt; 0.01). Before and after BTA and PPP, the mean VIH was 894 cc and 1209 cc (P &lt; 0.01), and the mean VAC was 6,692 cc and 9,183 cc (P &lt; 0.01). The VAC increased by 2,491 cc (P &lt; 0.01) and was greater than the mean VIH before PPP. An average reduction of 0.9% of the VIH/VAC ratio after BTA and PPP was obtained (p &gt; 0.05). All hernias were surgically reduced with mesh, hernia recurrence occurred in only two patients.Conclusions: The preoperative combined use of PPP and BTA increased the abdominal volume, lengthened the laterally retracted abdominal muscles, and facilitated laparoscopic closure of large complex ventral hernia.

scholarly journals Research of Ear Endoscopic Type I Tympanoplasty——Single-institution Experiences in China

2021 ◽  
Author(s):  
Di Ji ◽  
Jun Jie Yang ◽  
Xian Bai Zhu ◽  
Xue Qin Zhou ◽  
Xiao Jun Liang ◽  
...  
Keyword(s):  
Tympanic Membrane ◽  
Tympanic Membrane Perforation ◽  
Type I ◽  
Hearing Level ◽  
Hearing Improvement ◽  
Suppurative Otitis Media ◽  
Mean Values ◽  
Before And After ◽  
The Mean ◽  
Type I Tympanoplasty

Abstract Purpose: To assess outcomes of one-handed ear endoscopic Type I Tympanoplasty and summarize the experience. Methods: This study retrospectively analyzed 34 cases (23 females and 11 males) of one-handed ear Endoscopic Type I Tympanoplasty. Result: The mean values of air conduction threshold before and after surgery were 48.22+18.36dB HL and 34.34+19.83dB HL, respectively. The mean values of the air-bone gap before and after surgery were 23.60+12.18 dB HL and 11.05+6.62 dB HL, respectively. The results showed statistically significant differences in hearing improvement(P<0.05). Among 34 ears, 30 ears had effective hearing improvement. No vertigo, intracranial infection, suppuration, and any other postoperative complications occurred. Although 1 ear occurred tympanic membrane perforation again, all ears achieved dry. Conclusion: Ear endoscopic Type I Tympanoplasty with fewer complications and shorter surgery time were suitable for the chronic suppurative otitis media. Healing of the tympanic membrane and recovery of hearing level was ensured. However, the experience is still insufficient in China, so a large number of clinical workers need to exchange experience to promote the development of ear minimally invasive surgery.

Sign in / Sign up

Export Citation Format

Share Document