scholarly journals Hastanede Yatan COVID-19 Tanılı Hastalarda Görülen Nörolojik Semptomlar ve Hastalık Şiddeti ile İlişkisi

Author(s):  
Onur Serdar GENÇLER

Introduction: Coronavirus disease 2019 (COVID-19) spread rapidly all over the world, causing a pandemic. Neurological findings have also been reported in patients since the beginning of the pandemic. Recent data suggest that severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has both neurotropic and neurovirulent effects. This study aimed to evaluate the presence of neurological findings in hospitalized patients with the diagnosis of COVID-19 and the relationship of these findings with the severity of COVID-19. Material and Methods: Patients, positive for SARS-CoV-2 and had an indication of hospitalization were included in the study. Demographic characteristics, systemic symptoms, laboratory values and computed chest tomography findings of the patients were recorded. Neurological findings of the patients were evaluated by an experienced neurologist, and the relationship between these findings and the disease severity was analyzed. Results: The median age of 66 patients (33 females, 33 males) included in the study was 34.5. Of the patients, 33 (50%) had mild, 28 (42.4%) had moderate, 5 (7.6%) had severe COVID-19. The most common symptom was fever (48.5%). At least one neurologic symptom was detected in 43 patients (65.2%). Dysgeusia (27.3%), hyposmia-anosmia (27.3%), headache (25.8%) and muscle pain (24.2%) were the most common neurological symptoms. Among mild COVID-19 patients, individuals with neurological symptoms had longer hospitalization periods, than the patients without neurological symptoms (p=0.017). Conclusion: Neurological symptoms were observed in the majority of patients with COVID-19 in this study. Besides this study revealed that neurological symptoms may occur not only in aged intensive care patients with COVID-19, but also in young patients, with mild COVID-19. Therefore the hospitalization period may be prolonged in this patient group. In conclusion, regardless of its severity, physicians should keep in mind that COVID-19 may be a potential risk factor for neurological disorders. Keywords: COVID-19, pandemic, neurological symptoms, nervous system invasion

1975 ◽  
Vol 42 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Rainer Fogelholm ◽  
Olli Heiskanen ◽  
Olli Waltimo

✓The relationship of age to clinical and pathological findings was analyzed in 109 adult patients operated on because of chronic subdural hematoma. A well-formed membrane on the inner and outer surface of the hematoma was used as the criterion for chronicity of the hematoma. Younger patients had more evidence of increased intracranial pressure; older patients had more evidence of mental deterioration and pyramidal tract lesions. The interval from trauma to operation was shorter in the young patients. The thickness of the hematoma as measured from angiograms increased with the age of the patient. The cause of this difference is discussed.


2019 ◽  
pp. 014556131986766 ◽  
Author(s):  
Nurdoğan Ata ◽  
Necat Alataş ◽  
Esra Yılmaz ◽  
Ayşe Bülbül Adam ◽  
Bahri Gezgin

Introduction: Ankyloglossia is a congenital condition that restricts tongue mobility. The aim of this study is to evaluate the relationship between gender and pediatric ankyloglossia and evaluate the planning of ideal timing of surgery. Methods: The files of pediatric patients in the Turkish population treated surgically for tongue-tie between June 2014 to June 2018 were scanned retrospectively. Results: Three hundred and eighty-two pediatric patients were included in the study. Of these, 115 (30.1%) were female and 267 (69.9%) were male. The prevalence of ankyloglossia was significantly higher in males than in females ( P < .001). The age of the patients at time of surgery ranged from 1 day to 114 months. The most common indication was sucking/feeding difficulties (82%) in patients younger than 2 years, and the most common symptom was speech problems (67%) in patients aged 2 years and older. Conclusion: In our study, the prevalence of ankyloglossia in Turkish society was significantly higher in males. Frenectomy surgery is a safe procedure that can be performed on the first day of life in newborns.


2010 ◽  
Vol 32 (6) ◽  
pp. 377-384 ◽  
Author(s):  
Turgay Celik ◽  
U.Cagdas Yuksel ◽  
Selim Kilic ◽  
Halil Yaman ◽  
Atila Iyisoy ◽  
...  

Author(s):  
Pierre Sohier ◽  
Stéphanie Matar ◽  
Jean-François Meritet ◽  
Sara Laurent-Roussel ◽  
Nicolas Dupin ◽  
...  

Abstract Context: During the coronavirus disease 2019 pandemic, several studies have described a distinctive cutaneous manifestation with a clinical picture resembling chilblains or chilblain lupus in young patients. Objective: To report the histopathological description of a series of chilblain-like lesions appearing in the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic. Design: The study included 13 patients with cutaneous acral lesions resembling chilblains occurring in the setting of suspected SARS-CoV-2 infection with available skin biopsy. Results: Two main histopathological patterns were observed: a chilblain-like histopathological pattern (10 cases out of 13, 77%) and a thrombotic vasculopathy pattern (3 cases out of 13, 23% of cases). The chilblain-like histopathological pattern featured a superficial and deep perivascular infiltrate of lymphocytes of varying intensity. This infiltrate was sometimes peri-eccrine and alterations of eccrine glands were present in most cases. Vacuolar alteration of the basal layer of the epidermis was found in a majority of patients. Lichenoid interface dermatitis was rarely present. The thrombotic vasculopathy pattern featured an absent or mild inflammatory infiltrate, multiple intraluminal fibrin thrombi and ischemic epidermal necrosis. In both patterns, no true vasculitis was observed. No patient was tested positive for SARS-CoV-2 by polymerase chain reaction possibly due to the fact that these lesions may represent late cutaneous manifestations of the disease or are associated with an early effective immune response. Conclusion: The relationship of chilblain-like lesions to SARS-CoV-2 requires further investigations. Histopathological features mimic chilblains, chilblain lupus and less frequently a thrombotic vasculopathy. Response to viral infection might trigger diverse mechanisms leading to the two histopathological patterns described.


PEDIATRICS ◽  
1957 ◽  
Vol 20 (5) ◽  
pp. 848-865
Author(s):  
Magnus H. Agustsson ◽  
James W. DuShane ◽  
H. J. C. Swan

Data on hemodynamic findings in 19 infants and children with ventricular septal defect are presented. The ages of these patients ranged from 3 months to 14 years. Significant elevation of pulmonary arterial pressure was found in 17 of the 19 patients studied. Left-to-right shunts, at times of large magnitude, were found in all these patients. However, right-to-left shunts accounting for up to 50 per cent of systemic flow were also obtained, even in young patients. A history suggestive of cardiac failure was obtained in seven patients. Cyanosis was constant in one patient and was found intermittently in three others. A systolic murmur was heard in most cases in the third or fourth intercostal space. In four additional patients a diastolic murmur was also identified. The electrocardiogram provided valuable information, which correlated with the relationship of pulmonary and systemic arterial resistances, the status of intracardiac shunting of blood, and the total pulmonary blood flow. These factors are considered to be of paramount importance in selection of patients for the operative closure of ventricular septal defect. It has been demonstrated that the hemodynamic status of the patient may be difficult to assess at the time of cardiac catheterization because of the unpredictable effect of anesthesia on ventilation. The use of dye-dilution curves in the diagnosis and evaluation of both right-to-left and left-to-right shunts is a vital factor in the adequate assessment of the patients from the hemodynamic standpoint.


Author(s):  
N.S. Tuturov ◽  
O.V. Voeykova ◽  
V.G. Lebedev ◽  
Yu.Yu. Bosykh ◽  
N.L. Lezhava ◽  
...  

The article is devoted to treatment methods of young patients with class II malocclusion suffering from temporomandibular joint (TMJ) dysfunction. The authors proposed the improved treatment plan for the studied patients, which implies three stages: the first is a comprehensive functional analysis of the dental-maxillofacial system using digital technologies, the second one is the design, milling, manufacturing of occlusal overlays that allow to control occlusal plane slope and the last one is overlays luting and subsequent treatment with the help of aligners in order to normalize the relationship of the upper and lower teeth in three perpendicular planes with of retrusion control achieving. The described treatment method is disclosed in a clinical example.


Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.


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