scholarly journals Methicillin-resistant Staphylococcus aureus in the western region of Saudi Arabia: prevalence and antibiotic susceptibility pattern

2012 ◽  
Vol 32 (5) ◽  
pp. 513-516 ◽  
Author(s):  
Nagwa M. El Amin ◽  
Hani S. Faidah
2009 ◽  
Vol 35 (1) ◽  
pp. 28-30 ◽  
Author(s):  
Shamweel Ahmad ◽  
Faris Q. Alenzi ◽  
Nami Fawazan Al-Juaid ◽  
Shad Ahmed

Keywords: Antibiotic; Armed Forces Hospital; Methicillin resistant; Saudi Arabia; Staphylococcus aureusOnline: 22 May 2009DOI: 10.3329/bmrcb.v35i1.1983Bangladesh Med Res Counc Bull 2009; 35: 28-30


2014 ◽  
Vol 4 (7) ◽  
pp. 548-551 ◽  
Author(s):  
CP Bhatt ◽  
BMS Karki ◽  
B Baral ◽  
S Gautam ◽  
A Shah ◽  
...  

Background: Methicillin resistant Staphylococcus aureushas emerged as one of the most important nosocomial pathogens. It invokes a tremendous financial burden and enhanced morbidity and mortality due to difficult to treat systemic infections.Aim of this study was to determine antibiotic susceptibility pattern of Staphylococcus aureus and Methicillin resistant Staphylococcus aureus. Materials and Methods: Different clinical specimens were collected and processed for routine culture and antibiotic sensitivity test by standard microbiology techniques. Results: Out of 1173 samples received for microbiological examination, 100 were found to be S. aureus with 19% cases were Methicillin resistant Staphylococcus aureus (MRSA). Fourteen MRSA were found from inpatient and 5 were from outpatient. MRSA was found higher in female than male and maximum number (31.5%) was found in age group 0-10 years. Staphylococcus aureus was 100% sensitive to Vancomycin followed by Amikacin (90%), Gentamycin (83%), and tetracycline (81%). On urine isolates Nitrofurantoin(91.6%) was drug of choice. All the isolates were resistant to Penicillin G. In case of Methicillin resistant Staphylococcus aureus showed 100% sensitive to Vancomycin followed by Amikacin (84.2%), Tetracycline (63.1%), Ciprofloxacin (42%) and Gentamycin (36.8%). Among urine isolates Nitrofutantoin showed 87.5% sensitive followed by Norfloxacin (75%). Conclusion: Methicillin resistant Staphylococcus aureus was found 19% of Staphylococcus aureus isolates. It was most common in females, hospitalized patients and young age group. Vancomycin seems to be drug of choice followed by Amikacin. It would be helpful to formulating and monitoring the antibiotic policy and ensure proper empiric treatment. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10297 Journal of Pathology of Nepal (2014) Vol. 4, 548-551   


2016 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Ibrahim Al Balawi ◽  
Palanisamy Amirthalingam ◽  
Abdullah Abdul Khalig Alyoussef ◽  
Osama Salih Mohammed ◽  
Hyder Oman Mirghani ◽  
...  

The present study aimed to investigate the antibiotic susceptibility pattern of Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) in isolated wound cultures of the patients admitted in King Khalid Hospital, Tabuk, Kingdom of Saudi Arabia. A retrospective cohort study of 54 patients admitted with wound infections in the surgical department. Ethics committee approval was granted by the University of Tabuk and King Khalid Hospital, Kingdom of Saudi Arabia. Fifty-four adult patients (&gt;18 years old) diagnosed with moderate to severe skin and soft tissue infections were included in the study. 26 patients with isolated cultures of MRSA were compared with 28 patients with Methicillin-sensitive <em>Staphylococcus aureus</em> (MSSA) isolated cultures using Graph pad prism 4.0 version statistical databases. Overall, there was no significant difference in sensitivity (P = 0.2445) and resistance (P = 0.4215) between MRSA and MSSA cultures. However, it is interesting findings that Oxacillin and Fusidic acid had higher resistance in MRSA isolated cultures compared MSSA culture, on the other hand, Linezolid, Tigecycline and Nitrofurantoin shows 100% sensitivity in both MRSA and MSSA isolates. No significant difference between male and female regarding the sensitivity (P = 0.0638) and resistance (P = 0.3638). The current study emphasizes that Tigecycline, Nitrofurantoin and Fusidic acid were the best drugs in both MRSA and MSSA isolates. While, oxacillin showed 100% resistance to MRSA; but retain its efficacy on MSSA isolates.


Author(s):  
Ibrahim Al Balawi ◽  
Palanisamy Amirthalingam ◽  
Abdullah Abdul Khalig Alyoussef ◽  
Osama Salih Mohammed ◽  
Hyder Oman Mirghani ◽  
...  

The present study aimed to investigate the antibiotic susceptibility pattern of Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) in isolated wound cultures of the patients admitted in King Khalid Hospital, Tabuk, Kingdom of Saudi Arabia. A retrospective cohort study of 54 patients admitted with wound infections in the surgical department. Ethics committee approval was granted by the University of Tabuk and King Khalid Hospital, Kingdom of Saudi Arabia. Fifty-four adult patients (&gt;18 years old) diagnosed with moderate to severe skin and soft tissue infections were included in the study. 26 patients with isolated cultures of MRSA were compared with 28 patients with Methicillin-sensitive <em>Staphylococcus aureus</em> (MSSA) isolated cultures using Graph pad prism 4.0 version statistical databases. Overall, there was no significant difference in sensitivity (P = 0.2445) and resistance (P = 0.4215) between MRSA and MSSA cultures. However, it is interesting findings that Oxacillin and Fusidic acid had higher resistance in MRSA isolated cultures compared MSSA culture, on the other hand, Linezolid, Tigecycline and Nitrofurantoin shows 100% sensitivity in both MRSA and MSSA isolates. No significant difference between male and female regarding the sensitivity (P = 0.0638) and resistance (P = 0.3638). The current study emphasizes that Tigecycline, Nitrofurantoin and Fusidic acid were the best drugs in both MRSA and MSSA isolates. While, oxacillin showed 100% resistance to MRSA; but retain its efficacy on MSSA isolates.


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