Determinants of short-term mortality and morbidity after the complete repair of tetralogy of Fallot in infant groups under 12 months and one-four years of age

2010 ◽  
Vol 10 (6) ◽  
Author(s):  
Ahmet Sasmazel ◽  
Ali Fedakar ◽  
Ayse Baysal ◽  
Ahmet Caliskan ◽  
Onursal Bugra ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Short Term ◽  
Mortality And Morbidity ◽  
Complete Repair ◽  
Short Term Mortality

Impact of Perioperative Tachydysrhythmias on Mortality and Length of Stay in Complete Repair of Tetralogy of Fallot: A Multicenter Retrospective Cohort Study from the Pediatric Health Information System

Cardiology ◽  
2021 ◽  
pp. 1-7
Author(s):  
Aziez Ahmed ◽  
Parthak Prodhan ◽  
Beverly J. Spray ◽  
Elijah H. Bolin
Keyword(s):  
Information System ◽  
Length Of Stay ◽  
Health Information ◽  
Tetralogy Of Fallot ◽  
Health Information System ◽  
Inpatient Mortality ◽  
Pediatric Health ◽  
Mortality And Morbidity ◽  
Multiple Risk Factors ◽  
Complete Repair

Introduction: Tachydysrhythmias (TDS) frequently occur after complete repair of tetralogy of Fallot (TOF). However, not much is known about the effect of TDS on morbidity and mortality after TOF repair. We sought to assess the associations between TDS and mortality and morbidity after repair of TOF using a multicentre database. Materials and Methods: We identified all children aged 0–5 years in the Pediatric Health Information System who underwent TOF repair between 2004 and 2015. Codes for TDS were used to identify cases. Outcome variables were inpatient mortality and total length of stay (LOS). Univariate and multiple logistic and linear regression analyses were used to identify the effects of multiple risk factors, including TDS, on mortality and LOS. Results: A total of 7,749 patients met inclusion criteria, of which 1,493 (19%) had codes for TDS. There was no association between TDS and inpatient mortality. However, TDS were associated with 1.1 days longer LOS and accounted for 2% of the variation observed in LOS. Conclusion: After complete repair of TOF, TDS were not associated with mortality and appeared to have only a modest effect on LOS.

scholarly journals Earlier preterm birth is associated with a worse neurocognitive outcome in a rabbit model

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0246008
Author(s):  
Johannes van der Merwe ◽  
Lennart van der Veeken ◽  
Analisa Inversetti ◽  
Angela Galgano ◽  
Jaan Toelen ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Rabbit Model ◽  
Late Preterm ◽  
Short Term ◽  
Policy Makers ◽  
Mortality And Morbidity ◽  
Short Term Mortality ◽  
Neurobehavioral Testing ◽  
Postconceptional Age ◽  
Cross Fostering

Background Preterm birth (PTB) and particularly late preterm PTB has become a research focus for obstetricians, perinatologists, neonatologists, pediatricians and policy makers alike. Translational models are useful tools to expedite and guide clinical but presently no model exists that contextualizes the late PTB scenario. Herein we aimed to develop a rabbit model that echo’s the clinical neurocognitive phenotypes of early and late PTB. Methods Time mated rabbit does underwent caesarean delivery at a postconceptional age (PCA) of either 28 (n = 6), 29 (n = 5), 30 (n = 4) or 31 (n = 4) days, term = 31 d. Newborn rabbits were mixed and randomly allocated to be raised by cross fostering and underwent short term neurobehavioral testing on corrected post-natal day 1. Open field (OFT), spontaneous alteration (TMT) and novel object recognition (NORT) tests were subsequently performed at 4 and 8 weeks of age. Results PTB was associated with a significant gradient of short-term mortality and morbidity inversely related to the PCA. On postnatal day 1 PTB was associated with a significant sensory deficit in all groups but a clear motor insult was only noted in the PCA 29d and PCA 28d groups. Furthermore, PCA 29d and PCA 28d rabbits had a persistent neurobehavioral deficit with less exploration and hyperanxious state in the OFT, less alternation in TMT and lower discriminatory index in the NORT. While PCA 30d rabbits had some anxiety behavior and lower spontaneous alteration at 4 weeks, however at 8 weeks only mild anxiety driven behavior was observed in some of these rabbits. Conclusions In this rabbit model, delivery at PCA 29d and PCA 28d mimics the clinical phenotype of early PTB while delivery at PCA 30d resembles that of late PTB. This could serve as a model to investigate perinatal insults during the early and late preterm period.

scholarly journals Laparoscopy for rectal cancer reduces short-term mortality and morbidity: results of a systematic review and meta-analysis

2012 ◽  
Vol 27 (5) ◽  
pp. 1485-1502 ◽  
Author(s):  
Alberto Arezzo ◽  
Roberto Passera ◽  
Gitana Scozzari ◽  
Mauro Verra ◽  
Mario Morino
Keyword(s):  
Systematic Review ◽  
Rectal Cancer ◽  
Meta Analysis ◽  
Short Term ◽  
Mortality And Morbidity ◽  
Short Term Mortality

scholarly journals Estimation of Short-term Mortality and Morbidity Attributed to Fine Particulate Matter in the Ambient Air of Eight Iranian Cities

2018 ◽  
Vol 84 (3) ◽  
pp. 408-418 ◽  
Author(s):  
Majid Kermani ◽  
Gholamreza Goudarzi ◽  
Abbas Shahsavani ◽  
Mohsen Dowlati ◽  
Farshad Bahrami Asl ◽  
...  
Keyword(s):  
Particulate Matter ◽  
Fine Particulate Matter ◽  
Ambient Air ◽  
Short Term ◽  
Mortality And Morbidity ◽  
Fine Particulate ◽  
Short Term Mortality

scholarly journals B.01 Neonatal Neuro-Critical Care (NNCC) program associated with improved short term outcomes in neonates significant Hypoxic Ischemic Encephalopathy (HIE)

2018 ◽  
Vol 45 (s2) ◽  
pp. S12-S11
Author(s):  
S Roychoudhury ◽  
M Esser ◽  
J Buchhalter ◽  
L Bello-Espinosa ◽  
H Zein ◽  
...  
Keyword(s):  
Brain Injury ◽  
Hospital Stay ◽  
Primary Outcome ◽  
Average Length ◽  
Length Of Hospital Stay ◽  
Clinical Staging ◽  
Short Term ◽  
Mortality And Morbidity ◽  
Short Term Mortality ◽  
The Impact

Background: Despite advances in neonatal care, neonates with moderate to severe HIE are at high risk of mortality and morbidity. we report the impact of a dedicated NNCC team on short term mortality and morbidities. Methods: A retrospective cohort study on neonates with moderate to serve HIE between July 1st 2008 and December 31st 2017. primary outcome : a composite of death and/or brain injury on MRI. Secondary outcomes: rate of cooling, length of hospital stay, anti-seizure medication burden, and use of inotropes. A regression analysis was done adjusting for gestational age, birth weight, gender, out-born status, Apgar score at 10 minutes, cord blood pH, and HIE clinical staging Results: 216 neonates were included, 109 before NNCC implementation, and 107 thereafter. NNCC program resulted in reduction in the primary outcome (AOR: 0.28, CI: 0.14-0.54, p<0.001) and brain injury (AOR: 0.28, CI: 0.14-0.55, p<0.001). It decreased average length of stay/infants by 5 days (p=0.03), improved cooling rate (73% compared to 93% , p <0.001), reduced: seizure misdiagnosis (71% compared to 23%, P <0.001), anti-seizure medication burden (P = 0.001), and inotrope use (34% compared to 53%, p=0.004) Conclusions: NNCC program decreased mortality and brain injury , shortened the length of hospital stay and improved care of neonates with significant HIE.

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