Speech Audiometry Tests in Noise Are Impaired in Older Patients with Mild Cognitive Impairment: A Pilot Study

Abstract Background Cognitive disorders are one of the important issues in old age. There are many cognitive tests, but some variables affect their results (e.g., age and education). This study aimed to evaluate the reliability and validity of A Quick Test of Cognitive Speed (AQT) in screening for mild cognitive impairment (MCI) and dementia. Methods This is a psychometric properties study. 115 older adults participated in the study and were divided into three groups (46 with MCI, 24 with dementia, and 45 control) based on the diagnosis of two geriatric psychiatrists. Participants were assessed by AQT and Mini-Mental State Examination (MMSE). Data were analyzed using Pearson correlation, independent t-test, and ROC curve by SPSS v.23. Results There was no significant correlation between AQT subscales and age and no significant difference between the AQT subscales in sex, educational levels. The test-retest correlations ranges were 0.84 from 097. Concurrent validity was significant between MMSE and AQT. Its correlation was with Color − 0.78, Form − 0.71, and Color-Form − 0.72. The cut-off point for Color was 43.50 s, Form 52 s, and Color-Form 89 s were based on sensitivity and specificity for differentiating older patients with MCI with controls. The cut-off point for Color was 62.50 s, for Form 111 s, and Color-Form 197.50 s based on sensitivity and specificity measures for differentiating older patients with dementia and MCI. Conclusion The findings showed that AQT is a suitable tool for screening cognitive function in older adults.

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Abstract 14215: Cognitive Impairment in Adult Congenital Heart Disease Survivors: A Pilot Study

Circulation ◽

10.1161/circ.142.suppl_3.14215 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Carla P Rodriguez Monserrate ◽

Rajeshwari Jakkam ◽

Emily Clay ◽

Kimberlee Gauvreau ◽

Michelle Z GURVITZ

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Pilot Study ◽

General Population ◽

Ventricular Function ◽

Congenital Heart ◽

Education Level ◽

Factors Associated

Introduction: The most common comorbidities in children with congenital heart disease (CHD) are neurodevelopmental and psychosocial impairments, particularly in areas of executive function, memory, attention, and behavioral control. Limited studies in the adult CHD population suggest similar impairments exist and adults with CHD may be at increased risk for dementia. No studies have screened specifically for mild cognitive impairment and dementia in adult CHD patients. Methods: We performed a prospective cross-sectional study of adult CHD patients, ages 30-65 years, who were coming for routine clinic visits. We administered the Mini-Mental State Exam (MMSE) and scores were compared with population norms adjusted by age and education level. We also evaluated the association of MMSE scores with CHD complexity, demographic and clinical risk factors. Results: A total of 125 patients were recruited (55% male). The median age was 40 years (range 30-65). Almost all participants (97%) had a high school degree and 75% had some college education or advanced degrees. The majority of patients (94%) had moderate or complex CHD. Adjusting for age and education, CHD participants scored significantly lower than the general population (median 1 point lower, p=0.001). The greatest impairments occurred in recall and orientation. Factors associated with lower scores included decreased systemic ventricular function (p=0.028) and having ≥2 cardiac catheterizations (p=0.006). Five percent of the total cohort met the general threshold for mild cognitive impairment (MMSE<24). Clinical factors associated with this degree of cognitive impairment were duration of cyanosis (p=0.005) and decreased systemic ventricular function (p=0.003). Conclusions: Our pilot study showed that, when adjusted for age and education level, adult CHD patients had significantly lower MMSE scores than the general population, with 5% meeting criteria for mild cognitive impairment. These findings suggest that subtle and early neurodevelopmental changes are present in the adult CHD population. Further studies are needed to investigate those changes and evaluate potential disease modifying therapies that might influence long-term outcomes in the adult CHD population.

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Effects of a Portable Computerized Cognitive Training System on the Visual-perceptual Function of Stroke Patients with Mild Cognitive Impairment : A Pilot Study

Journal of the Korea Entertainment Industry Association ◽

10.21184/jkeia.2019.12.13.8.603 ◽

2019 ◽

Vol 13 (8) ◽

pp. 603-610

Author(s):

Min-Jae Jeon ◽

Jong-Hoon Moon

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Pilot Study ◽

Cognitive Training ◽

Training System ◽

Stroke Patients ◽

Computerized Cognitive Training ◽

Perceptual Function

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P2-508: COGNITIVE AND NEURAL CORRELATES OF THREE PERFORMANCE-BASED FUNCTIONAL ASSESSMENTS IN NORMAL AGING AND MILD COGNITIVE IMPAIRMENT: A PILOT STUDY

Alzheimer s & Dementia ◽

10.1016/j.jalz.2018.06.1202 ◽

2006 ◽

Vol 14 (7S_Part_17) ◽

pp. P927-P927

Author(s):

Luis Daniel Medina ◽

Kate S. Heffernan ◽

Christopher M. Filley ◽

Brianne M. Bettcher

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Pilot Study ◽

Neural Correlates ◽

Normal Aging ◽

Functional Assessments

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Electromyographic Activity in the EEG in Alzheimer's Disease: Noise or Signal?

International Journal of Alzheimer s Disease ◽

10.4061/2011/547024 ◽

2011 ◽

Vol 2011 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Karin van der Hiele ◽

Robert H. A. M. Reijntjes ◽

Alla A. Vein ◽

Rudi G. J. Westendorp ◽

Mark A. van Buchem ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Pilot Study ◽

Amnestic Mild Cognitive Impairment ◽

Theta Activity ◽

Emg Activity ◽

Electromyographic Activity ◽

Behavioural Aspects

Many efforts have been directed at negating the influence of electromyographic (EMG) activity on the EEG, especially in elderly demented patients. We wondered whether these “artifacts” might reflect cognitive and behavioural aspects of dementia. In this pilot study, 11 patients with probable Alzheimer's disease (AD), 13 with amnestic mild cognitive impairment (MCI) and 13 controls underwent EEG registration. As EMG measures, we used frontal and temporal 50–70 Hz activity. We found that the EEGs of AD patients displayed more theta activity, less alpha reactivity, and more frontal EMG than controls. Interestingly, increased EMG activity indicated more cognitive impairment and more depressive complaints. EEG variables on the whole distinguished better between groups than EMG variables, but an EMG variable was best for the distinction between MCI and controls. Our results suggest that EMG activity in the EEG could be more than noise; it differs systematically between groups and may reflect different cerebral functions than the EEG.

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