Relationship of Febrile Convulsion with Iron Deficiency Anemia and Zinc Deficiency

2016 ◽  
Vol 6 (2) ◽  
pp. 94-97
Author(s):  
Hasim Gencer ◽  
Ihsan Kafadar ◽  
Gulsen Kose ◽  
Yildiz Yildirmak
Author(s):  
Ayse Betul Ergul ◽  
Cem Turanoglu ◽  
Cigdem Karakukcu ◽  
Serap Karaman ◽  
Yasemin Altuner Torun

2017 ◽  
Vol 4 (5) ◽  
pp. 1599
Author(s):  
Gautam Shah ◽  
Ritesh Parmar

Background: Febrile seizures are the most common cause of convulsions in children between 6 months to 5 years, occurring in 2-5% of children. Iron deficiency is postulated as a risk factor for febrile seizures in children and it is an easily correctable condition. The objective of the study was to study the clinical profile and risk factors of febrile convulsions and to establish an association between febrile seizure and iron deficiency anemia.Methods: The study was carried out in Department of Pediatrics, Dhiraj General Hospital, Piparia, a tertiary care teaching hospital. 34 cases and 34 controls were included in the study. Controls were children of same age group presenting with short febrile illness but without any seizures. Febrile seizures were defined according to the AAP (American Academy of Pediatrics) criteria. Iron deficiency was diagnosed by hematologic investigations of haemoglobin value < 11 g/dl, MCV <70 fL and RDW > 15.6%.Results: Iron deficiency anemia was present in 23.52% (8/34) of cases as compared to 17.64% (6/34) in the control group. Odds ratio was 1.436 (95% CI 0.439-4.669, p value 0.549), which suggest there is no significant association of iron deficiency anemia with febrile convulsions. Subgroup analysis for association of iron deficiency anemia with simple febrile convulsion cases showed Odds ratio of 1.11 (95% CI 0.298-4.138), which suggests there is poor association of iron deficiency anemia with simple febrile convulsions. Subgroup analysis for association of iron deficiency anemia with complex febrile convulsion cases showed Odds ratio of 2.809 (95% CI 0.521-15.041), which suggests there is poor association of iron deficiency anemia with complex febrile convulsions. Wide confidence interval indicates less sample size. Study with large sample size is required for reliable interpretation.Conclusions:The study reveals iron deficiency anemia is not a significant risk factor in children presenting with febrile seizures. Further study with large sample size is required. 


2021 ◽  
Vol 38 (2) ◽  
pp. 111-114
Author(s):  
Nevin ALAYVAZ ASLAN ◽  
Engin KELKİTLİ ◽  
Nurinnisa ÖZTÜRK

Iron deficiency and zinc deficiency are known to disturb cognitive functions especially in infants and preschool children. Our purpose was to evaluate the effect of zinc deficiency and iron deficiency on cognitive function (with Montreal Cognitive Assessment [MoCA] score) in females. We designed a randomized controlled prospective study. 41 iron deficient female patients and 40 healthy volunteers were involved in the study. The average MoCA score ± SD was 24,63 ± 4,3 (range 11–30) in iron deficiency anemia (IDA), and 27.43± 2.02 (23-30) in healthy volunteers. Zinc level was 97.06 (40.8–146.8) mg/dl and 257.5 (128.2–463.7) in IDA and healthy volunteers respectively. MoCA score (r= 0.803, p<0,01), were significantly correlated with Zinc level in iron deficient group. We found that there was a statistically important linear relationship between MoCA score and zinc level in female patients with iron deficiency anemia.


2017 ◽  
Vol 19 (1) ◽  
pp. 61-67 ◽  
Author(s):  
Cahyaningtyas Triwinarni ◽  
Th Ninuk Sri Hartini ◽  
Joko Susilo

Background : Nutritional problems frequently experienced by adolescents is anemia. Anemia is a condition with blood hemoglobin levels were lower than normal as a result of the inability of tissues forming red blood cells in its production in order to maintain hemoglobin levels at normal levels. The prevalence of anemia in women age 15 and older, according to Riset Kesehatan Dasar in 2013 by 22.7%. Objective : The purpose of this study analyze the relationship between nutritional status and the incidence of iron deficiency anemia among high school students in Pakem. Method : This observational study using cross sectional approach, implemented in four high schools in the District of Pakem. The population in this study were students of class X and XI in four high school in Pakem. The independent variables were the nutritional status. The dependent variable is the iron anemia. Hemoglobin levels were measured by the method cyanmethemoglobin, weight was measured with a digital bathroom scales, height measured by microtoise. Data analysis used chi-square statistic. Conclusion : Based on the analysis proves that there is a relationship of nutritional status according to BMI / U with the incidence of iron deficiency anemia in high school in Pakem with p = 0.017.   Keywords: nutritional status , anemia , High School students


2017 ◽  
Vol 35 (2) ◽  
pp. 75-79
Author(s):  
Sharmistha Ghosal

Background and objective: Febrile Seizure (FS) is the commonest seizure disorder among under 5 children. Iron deficiency is a documented risk factor of FS and as the data about the relationship of iron deficiency with FS among Bangladeshi children is scanty, this study was undertaken to assess the association of Serum Ferritin to simple FS.Materials and Methods: This case control study was conducted at the department of pediatrics of SSMC & Mitford Hospital during 7th May 2011 to 6th January 2012 on consecutive 120 children aged between five months to six years who fulfilled the inclusion criteria were considered as cases. Similar number of age and sex matched children admitted with fever without seizures were taken as controls. All candidates were gone through CBC with RBC indices and serum ferritin and iron deficiency anemia was diagnosed on the basis of mentioned tests.Results: The results showed that majority of the cases were male (66.7%) and most of them were between 13-24 months of age (51.7%). Mean duration of convulsion was less than 5 minutes in 70% of the cases. Level of Hb was low in both the cases and controls but the other RBC indices for anemia like MCV, MCH, MCHC and serum ferritin were significantly lower among the febrile seizures group in comparison to controls. The chi-square test is indicated as a significant difference between two groups and odds ratio is 6.0 which signifies that febrile seizure group were 6.0 times more likely to develop iron deficiency anemia compared to control group.Conclusion: The findings suggest that children with febrile seizure have association with iron deficiency anemia (which is evident by microcytic hypochromic anemia and low serum ferritin level) .This means low serum ferritin and presence of anemia can serve as a risk factor for febrile seizure in children.J Bangladesh Coll Phys Surg 2017; 35(2): 75-79


2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A215-A215
Author(s):  
M. Inalhan ◽  
Y. Feyza ◽  
T. Ozlem ◽  
A. Ozlem ◽  
C. Mehmet ◽  
...  

2018 ◽  
Vol 50 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Ayse Betul Ergul ◽  
Cem Turanoglu ◽  
Cigdem Karakukcu ◽  
Serap Karaman ◽  
Yasemin Altuner Torun

2020 ◽  
pp. 1-3
Author(s):  
Lakshmi M ◽  
Sumapriya M ◽  
Channamsetty Anusha

BACKGROUND: Febrile convulsion (FC) is the most common CNS disorder in childhood. 2-5% of children (or 4.8 out of every 1000) are affected every year. Studies conducted on the effect of iron deficiency on febrile convulsions found in children have yielded completely conflicting results. Iron deficiency has been a risk factor for febrile convulsions in some studies, while in others, it was proved to be protective against febrile seizure as iron deficiency increases the threshold of neuron excitation. Aims: To study the relationship between iron deficiency anemia and febrile convulsion in children to prevent the treatable cause of FC. Objectives: Is to determine the relationship between iron deficiency anemia and febrile seizures and to find out the incidence of anemia in the febrile seizure in males and females. Methods: A Hospital-based observational study carried out at Andhra Mahila Sabha Hospital, Hyderabad, during the period May 2014 to May 2016 involving children aged about 6months to 5 years of age group with typical febrile convulsions meeting inclusion and exclusion criteria. The temperature at admission and nutritional status was recorded, and investigations like hemoglobin, blood indices (MCV, MCH, MCHC), RDW (Red Cell Distribution Width), serum iron, and peripheral smear did for detection of iron deficiency anemia and their relationship with febrile seizure was observed. Results: Out of 350 children enrolled, 131 (37.4%) were female, and 219 (62.6%) were males. In our study males was slightly more prone to febrile seizure with the ratio of M: F is 1.6:1. There is a significant association of iron deficiency anemia with FC, and there is increased frequency with increased incidence of iron deficiency anemia,(i.e.) seizures tend to repeat itself in the presence of iron deficiency anemia ( with P-value of <0.001, at CI of 95%). Conclusion: low serum iron levels and the presence of anemia can serve as strengthening factors for febrile seizures in children. Accordingly, children with febrile seizures are suggested to be monitored for the diagnosis and treatment of IDA.


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