scholarly journals Treatment of metabolic syndrome and quality of life in patients with schizophrenia: a systematic review

Author(s):  
MAICA RUIZ-PEREZ ◽  
SALVADOR LLISTAR-VERDÚ ◽  
LAIA FARRAS-PERMANYER ◽  
TARY GOMEZ-HINOJOSA

Schizophrenia affects around 0.3–0.7% people at some point in their lives - or 24 million people worldwide. This review covers topics of broad general interest that have seen significant development or progress in recent years. This paper aims to review the scientific literature of the past 10 years on metabolic syndrome regarding the quality of life of people with schizophrenia and the interventions carried out. A bibliographical search was conducted on Web of Science and PsycINFO, using the keywords of this study. More than 90 publications were found, 70 of which met the requirements. The main topic was schizophrenia, metabolic syndrome and quality of life. Those that focused on the effects of drugs were excluded. Although the association between mental illness and physical health problems has been convincingly demonstrated, numerous studies support the existence of dual physical health care neglect of people with schizophrenia. On the other hand, the modifiable risk factors are clearly defined to improve the physical health of these patients as well as the aspects which should be included in any approach to improve metabolic syndrome in particular, physical health in general, and thus modify the self-perceived quality of life. The data on psychoeducational treatments for this population were insufficient. However, some studies show that the implementation of behavioral interventions in clinical practice can help patients improve their overall health and prevent chronic disease. There are few studies on the application of ehealth devices to schizophrenic patients.

2017 ◽  
Vol 29 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Mir Hasan Shakil Mahmud ◽  
Bushra Yeasmin ◽  
Shipra Mandal

Schizophrenia is one of the major mental disorders which affect individual’s thinking ability, social interaction or attention. It affects person’s entire quality of life. The purpose of the study was to find out the quality of life of schizophrenic patient in Bangladesh. Cross sectional study design was used to conduct this study. The convenient sampling procedure was used throughout the process of participant’s selection and the numbers of respondents were 83. The study was carried out at National Institute of Mental Health and Hospital (NIMH), Dhaka. Data was collected by using face to face interview with a structured questionnaire WHOQOL-BREF (The World Health Organization Quality of Life- BREF) scale. It was found that most of the participants lead poor to moderate quality of life in four domains of the WHOQOL-BREF scale. Results showed that mean scores were for physical health (mean 2.7, SD+0.106); psychological health (mean 2.108, SD +0.0787); social relationship (mean 2.226; SD+0.116) and environmental health (mean 2.47; SD+0.077).This study indicated that, quality of life poor on psychological domain. It was also found statistically significance with age and social relationship domain (p value 0.005< 0.05); marital status and physical health domain (p value 0.004<0.05); educational level and physical health domain (p value 0.005<0.05) and environmental health domain (p value 0.025<0.05). There were no statistically significant difference between gender and other variables. Schizophrenia affects all aspects of person’s life such as physically, psychologically, socially and economically. Schizophrenic patients as well as their family members led very poor quality of life.Bang J Psychiatry June 2015; 29(1): 30-34


2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Faith Agbozo ◽  
Edith Bannerman ◽  
Senam Klomegah ◽  
Francis Zotor

AbstractMetabolic syndrome (MetS), which refers to co-occurrence of cardiovascular risks primarily obesity, hypertension, insulin resistance and atherogenic dyslipidemia was previously uncommon in sub-Sahara African. But it is increasingly becoming a public health concern heightened by the epidemiological transition associated with excess energy intake, sedentary lifestyles and urbanization. The aim of this study was to assess the dietary, lifestyle and physiologic risk factors associated with MetS and the effect on perceived quality of life. The design was one-to-one age and sex-matched case-control study. MetS was defined as concomitant adiposity, hypertension and diabetes. Cases (n = 76) were recruited in the diabetic clinic of a municipal hospital in Ghana while controls (n = 76) were recruited in the communities in which the cases lived. Lifestyle habits and physical activity were assessed using a validated lifestyle and habits questionnaire while habitual dietary intakes were assessed using a food frequency questionnaire. Anthropometry, blood pressure and fasting capillary glucose were measured. Differences between cases and controls were tested using McNemar and paired t-test tests. Crude odds ratio (COR) for MetS was estimated using conditional logistic regression.Mean age of participants was 57.31 ± 5.46 years (range 45–65 years). Females constituted the majority (95%, n = 144). Among the cases and controls, lateral obesity (100% vs 60.5%), central obesity (98.7% vs 36.8%), hypertension (90.8% vs 2.6%) and diabetes (72.4% vs 1.3%) differed significantly. Fewer cases (10.5%) consumed diversified and healthy diets compared to the controls (77.6%) (p = 0.001). Significant number of cases felt a high risk for illness based on how they assessed their physical health (73.7% vs 2.6%), exercise and fitness regime (88.2% vs 13.2%), nutrition and weight control (14.5% vs 1.3%) and psychological health (19.7% vs 0%). However, none felt socially unhealthy. Lower risk for MetS was found among participants who had at least secondary education (COR:0.17 95% CI:0.04–0.73) and lived in a peri-urban setting (COR:0.22 95% CI:0.09–0.53) while unemployment (COR:9.00 95% CI:1.26–64.35) and central obesity (COR: 48.0 95% CI: 6.62–147.74) were associated with higher risk. MetS adversely affected general sense of wellbeing of the middle age adults. Obesity was an important predictor. Educational interventions to promote diversification of dietary intakes and enhance weight control are crucial to reduce MetS and could improve the quality of life of those affected. These interventions should be integrated into already existing community-based social support, and health systems.


2011 ◽  
Vol 198 (3) ◽  
pp. 179-188 ◽  
Author(s):  
David Taylor ◽  
Nicholas Meader ◽  
Victoria Bird ◽  
Steve Pilling ◽  
Francis Creed ◽  
...  

BackgroundAntidepressant drugs are widely used in the treatment of depression in people with chronic physical health problems.AimsTo examine evidence related to efficacy, tolerability and safety of antidepressants for people with depression and with chronic physical health problems.MethodMeta-analyses of randomised controlled efficacy trials of antidepressants in depression in chronic physical health conditions. Systematic review of safety studies.ResultsSixty-three studies met inclusion criteria (5794 participants). In placebo-controlled studies, antidepressants showed a significant advantage in respect to remission and/or response: selective serotonin reuptake inhibitors (SSRIs) risk ratio (RR) = 0.81 (95% CI 0.73–0.91) for remission, RR = 0.83 (95% CI 0.71–0.97) for response; tricyclics RR = 0.70 (95% CI 0.40–1.25 (not significant)) for remission, RR = 0.55 (95% 0.43–0.70) for response. Both groups of drugs were less well tolerated than placebo (leaving study early due to adverse effects) for SSRIs RR = 1.80 (95% CI 1.16–2.78), for tricyclics RR = 2.00 (95% CI 0.99–3.57). Only SSRIs were shown to improve quality of life. Direct comparisons of SSRIs and tricyclics revealed no advantage for either group for remission, response, effect size or tolerability. Effectiveness studies suggest a neutral or beneficial effect on mortality for antidepressants in participants with recent myocardial infarction.ConclusionsAntidepressants are efficacious and safe in the treatment of depression occurring in the context of chronic physical health problems. The SSRIs are probably the antidepressants of first choice given their demonstrable effect on quality of life and their apparent safety in cardiovascular disease.


2020 ◽  
Vol 8 (3) ◽  
pp. 273
Author(s):  
Yudistira Afconneri ◽  
Wulan Getra Puspita

Schizophrenia is a mental disorder characterized by symptoms such as hallucinations and delusions. These symptoms can affect the quality of life in people with schizophrenia. From the data of Tanjung Paku Health Center, which suffers from schizophrenia as many as 46 people. The purpose of this study was to describe the life quality factors of schizophrenics in the working area of Tanjung Paku health center in Solok city in 2019. The purpose of this study was to describe the life quality factors of schizophrenics in the working area of Tanjung Paku health center in Solok city in 2019. This research is descriptive, carried out on June 11 to June 13, 2019 in the working area of Tanjung Paku Health Center, Solok City. The population in this study were all schizophrenic patients in the working area of Tanjung Paku Community Health Center in Solok City, amounting to 46 people. Sampling is done by means of total sampling totaling 25 people. Data is collected by means of observation and interviews, data processing is done by univariata analysis. The results of the study of 25 respondents found that most (56.0%) of respondents had poor physical health, most (68.8%) of respondents had bad social, most (56.0%) respondents had uncontrolled emotions, most of them (72%) respondents who can do activities well.


2021 ◽  
Vol 9 (2) ◽  
pp. 93-102
Author(s):  
Tunjung Sri Yulianti

Latar Belakang: skizofrenia merupakan suatu hal yang melibatkan banyak sekali faktor. Faktor tersebut adalah perubahan struktur fisik otak,  perubahan struktur kimia otak dan faktor genetik. Skizofrenia merupakan penyakit neurologis yang mempengaruhi persepsi klien,  cara berfikir,  bahasa,  emosi,  dan perilaku sosialnya.Terdapat beberapa faktor yang dapat mempengaruhi kualitas hidup pasien skizofrenia. Karena itu, mengetahui faktor kualitas hidup pasien skizofrenia sangat penting dimana dapat dijadikan acuan untuk mengidentifikasi kualitas hidup pasien skizofrenia dan faktor yang mempengaruhinya. Tujuan penelitian: untuk mengetahui faktor yang mempengaruhi kualitas hidup pasien skizofrenia. Metode: desain penulisan adalah literatur review. Populasi diambil dari seluruh jurnal penelitian dengan topik kualitas hidup pasien skizofrenia. Sampel pada penelitian ini adalah 5 jurnal tentang kualitas hidup pasien skizofrenia yang memenuhi kriteria inklusi. Hasil: hal-hal yang terkait dengan kualitas hidup pasien skizofrenia yaitu kesehatan fisik, kesehatan psikologis, hubungan sosial, lingkungan kesehatan dan sosial, fungsi sosial, kepatuhan minum obat dan kepatuhan berobat.  Kesimpulan: faktor yang mempengaruhi kualitas hidup pasien skizofrenia mencakup fungsi keluarga dan dukungan keluarga, stigma diri, harga diri, daya tilik diri.     Kata kunci: skizofrenia, kualitas Hidup   FACTORS AFFECTING THE QUALITY OF LIFE OF SCHIZOPHRENIC PATIENTS : LITERATURE REVIEW   Tunjung Sri Yulianti   Abstract   Background: schizophrenia is a multi-factor issue. These factors are changes in the physical structure of the brain, changes in the chemical structure of the brain and genetic factors. Schizophrenia is a neurological disease that affects the client's perception, way of thinking, language, emotions, and social behavior.There are several factors that can affect the quality of life of schizophrenic patients. Therefore, knowing the quality of life factors of schizophrenia patients is very important which can be used as a reference. So this study was conducted to find appropriate prevention efforts so that the quality of life of schizophrenia patients was not low. The aim of the study: to determine the factors that affect the quality of life of schizophrenic patients. Method: the writing design is a literature review. Literature review is the process of research or writing scientific papers, where literature is used as a data source. The population was taken from all journals of quality of life for schizophrenia patients. The samples in this scientific paper were 5 journals of quality of life for schizophrenia patients that met the inclusion criteria. Result: things related to the quality of life of schizophrenic patients, namely physical health includes: daily life activities, dependence on drugs and medical assistance, psychological health includes: body image and appearance, negative feelings, feelings of spirituality / religion / personal beliefs, thinking, relationships. social includes: personal relationships, social support and sexual activity. Environment includes: financial resources, freedom, physical security, health and social services: affordability and quality, home environment. Conclusion: factors that affect the quality of life of schizophrenic patients include physical health, psychological health, social and environmental relationships   Keywords: schizophrenia, quality of life.  


2010 ◽  
Vol 6 (02) ◽  
pp. 101-108 ◽  
Author(s):  
Tomás Sánchez-Araña Moreno ◽  
Sergio Ruiz-Doblado ◽  
José Luis Hernández-Fleta ◽  
Ramon Touriño-Gonzalez ◽  
Petra León-Pérez

2014 ◽  
Author(s):  
Izaddin A Aziz ◽  
Claire V Hutchinson ◽  
John Maltby

The current study explores the perceived quality of life of Syrian refugees who have entered the Kurdistan Region of Iraq. Two hundred and seventy participants residing in refugee camps in the Erbil region in Kurdistan completed the WHOQOL-BREF, which measures quality of life (QoL) within four domains; physical, psychological, social relationships and environment. Syrian refugees in Kurdistan scored significantly lower for general population norms on physical health, psychological and environment QoL, and score significantly lower for physical health and psychological QOL for refugees in the Gaza strip. However, respondents in the current sample scored significantly higher on environment QoL to refugees in the Gaza strip, and significantly higher on all the QoL domains than those reported for refugees in West Africa. Finally, Syrian refugees in Kurdistan scored significantly higher than general population norms for environment-related QoL. The current findings provide the first report of QoL domain scores among Syrian refugees, and position the QoL scores among this sample, for the most part, within the range mean scores for QoL domains of other samples, and may, for environment-related QoL, be higher than for other refugee samples.


2014 ◽  
Author(s):  
Izaddin A Aziz ◽  
Claire V Hutchinson ◽  
John Maltby

The current study explores the perceived quality of life of Syrian refugees who have entered the Kurdistan Region of Iraq. Two hundred and seventy participants residing in refugee camps in the Erbil region in Kurdistan completed the WHOQOL-BREF, which measures quality of life (QoL) within four domains; physical, psychological, social relationships and environment. Syrian refugees in Kurdistan scored significantly lower for general population norms on physical health, psychological and environment QoL, and score significantly lower for physical health and psychological QOL for refugees in the Gaza strip. However, respondents in the current sample scored significantly higher on environment QoL to refugees in the Gaza strip, and significantly higher on all the QoL domains than those reported for refugees in West Africa. Finally, Syrian refugees in Kurdistan scored significantly higher than general population norms for environment-related QoL. The current findings provide the first report of QoL domain scores among Syrian refugees, and position the QoL scores among this sample, for the most part, within the range mean scores for QoL domains of other samples, and may, for environment-related QoL, be higher than for other refugee samples.


2017 ◽  
Vol 41 (S1) ◽  
pp. S192-S193
Author(s):  
S. Di Marco ◽  
A. Feggi ◽  
E. Cammarata ◽  
L. Girardi ◽  
F. Bert ◽  
...  

IntroductionResilience is commonly defined as positive adaptation to adverse events or as the ability to maintain or regain mental health after exposure to difficulties. According to the bio-psycho-social model, resilience is influenced by self-esteem, coping strategies and personality traits. In schizophrenic patients, resilience seems to affect real-life functioning, while in mood disorders, resilience influences the longitudinal course of the disorder, reducing the frequency of relapses and improving drugs response.ObjectivesThe aim of this study is to asses levels of resilience and self-esteem, coping strategies, perceived quality of life and temperament characteristics in a sample composed by patients with major depressive disorder and patients affected by schizophrenia.MethodsWe collected a sample composed by 40 patients with major depressive disorder and 40 patients affected by schizophrenia patients recruited at the “Maggiore della Carità” Hospital in Novara, Italy. The assessment protocol included: Resilience Scale for Adults (RSA), Coping Orientation to Problems Experienced Inventory–Brief (BRIEF–COPE), Rosenberg Self-esteem Scale (RSES), Paykel List Of Stressful Events, Temperamental and Character Inventory (TCI) and Short form 36 (SF-36). Comparison of qualitative data was performed by means of the χ2, a t-test was performed for continuous normal-distribution variables otherwise a non-parametric Mann–Whitney test was performed. Statistical significance was set at P ≤ 0.05.ConclusionsIn patients with major depressive disorder resilience were associated with a good self-perception of physical and mental health, higher self-esteem levels and problem-focused/emotion focused coping strategies. In schizophrenic patients, sample there was no positive correlation between resilience and perceived quality of life. Further implications will be discussed.Disclosure of interestThe authors have not supplied their declaration of competing interest.


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