Evaluation Of Drug Utilization Patterns Based On World Health Organization Drug Use Indicators At Outpatients Clinics

2020 ◽  
Vol 11 (3) ◽  
pp. 20031489-20031489
Author(s):  
Kayamkani Abedulla Khan
2020 ◽  
Vol 15 ◽  
Author(s):  
Solomon Hambisa ◽  
Rediet Feleke ◽  
Ameha Zewudie ◽  
Mohammed Yimam

Background:: Rational drug use comprises aspects of prescribing, dispensing and patient use of medicines for different health problems. This study is aimed to assess drug prescribing practice based on the world health organization prescribing indicators in Mizan-Tepi University teaching hospital. Methods:: An institutional based retrospective cross sectional study was conducted to evaluate prescribing practices in Mizan-Tepi University teaching hospital. Data were collected based on World health organization drug use indicators using prescription papers. 600 prescriptions dispensed through the general outpatient pharmacy of the hospital were collected by systematic random sampling method from prescriptions written for a 1-year time in Mizan-Tepi University teaching hospital. Results:: The present study found that the average number of drugs per prescription was 2.04 ± 0.87 in Mizan-Tepi University teaching hospital with a range between 1 and 5. Prescribing by generic name was 97.6 % and 47.8% of prescriptions contained antibiotics in the hospital. 27.7% of prescriptions contained at least one injectable medication in Mizan-Tepi University teaching hospital. From prescribed drugs, 96.7% of them were prescribed from Ethiopian essential drug list. Conclusion:: Present study indicated that the average number of drugs prescribed per encounter, the percentage of generic prescribing and prescribing from the EDL were close to optimal value. However, the percentage of encounters with antibiotics and injections prescribed were found be very high. Thus, the study highlights some improvements in prescribing habits, particularly by focusing on the inappropriate consumption of antibiotics and injections.


2021 ◽  
Vol 14 (1) ◽  
pp. 27-31
Author(s):  
Rajasmith Paul McGrath ◽  
Murugakadavul Arumugavignesh ◽  
Rajaram Abishek ◽  
S Uduman Mohamed Afreeth ◽  
Nagendran Ponraj ◽  
...  

2017 ◽  
Vol 8 ◽  
pp. 117739361770334 ◽  
Author(s):  
Sandeep Lahiry ◽  
Avijit Kundu ◽  
Ayan Mukherjee ◽  
Shouvik Choudhury ◽  
Rajasree Sinha

Objective: To analyze drug utilization (DU) pattern of antidiabetes drug (ADD) prescription in elderly type 2 diabetes mellitus (T2DM) in rural West Bengal based on 2016 World Health Organization (WHO) Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) Index. Methods: This was a prospective observational study. Prescription data of 600 elderly patients (age > 60 years) attending outpatient clinic were screened over 12 months (January 2015 to January 2016) from 5 different rural hospitals in West Bengal. Pooled data were sorted and classified in accordance with 2016 ATC/DDD WHO Index. Direct cost associated and consumption of ADD were measured as DDD/1000 patients/day. The adverse drug reactions (ADRs) related to antidiabetic medicines were monitored. Results: During the study period, mean age of patients recorded was 66.4 ± 5.0 years, with 66.6% (n = 396) having history of T2DM > 5 years. Follow-up encounters (n = 2328) revealed metformin (94.67%), sulfonylureas (SUs) (50.54%), pioglitazone (24.22%), voglibose (22.50%), insulin (9.75%), and acarbose (6.82%) to be more prevalent, constituting DU 90% (92.01%). Combination of metformin plus SU was recorded in most of the patients (56%). Insulin, however, was found to be an underutilized class ( P < .005). The DDD/1000 patients/day of metformin (2.918), glimepiride (1.577), and gliclazide (0.069) conformed to 2016 WHO ATC/DDD Index. The total ADD consumption during study period was 5.03 DDD/1000 patients/day. The average drug cost per encounter per day was Rs 11.24 ± 2.01. Nineteen ADRs were reported and their descriptions were found to be of hypoglycemia (n = 9), pedal edema (n = 2), and gastrointestinal upsets (n = 8). Target glycemic status was achieved in 40% monthly follow-up encounters. Low-store drug availability and poor compliance to treatment (>60%) were major determinants. Lack of regular aerobic exercises (>85%) and proper knowledge regarding medical nutrition therapy (MNT) (>80%) and low average consultation time (3.5 ± 0.6 minutes) were important contributing factors. Conclusions: The study exhibited increased utilization of 2 drug combinations of oral ADD and lower utilization of insulin during study period. Such inferences merit further exploration.


2020 ◽  
Vol 8 ◽  
pp. 205031212092643
Author(s):  
Amrita Aryal ◽  
Asmita Dahal ◽  
Rajeev Shrestha

Background: The basic health service is a fundamental right of every citizen. Appropriate use of medicine is an essential component for the quality of health. Drug use evaluation is a systematic and criteria-based drug evaluation, which ensures the appropriate use of the drug. The purpose of this study was to analyze the drug use situation in primary healthcare centers of Kathmandu valley. Methodology: A cross-sectional descriptive study was performed in all primary healthcare centers of Kathmandu valley. Six hundred prescriptions were analyzed retrospectively, choosing a simple random sampling method for prescribing indicators. One hundred twenty patients were interviewed for patient-care indicators, and health facility representatives were interviewed for health facility indicators. Drug use indicators developed by World Health Organization/International Network for Rational Use of Drugs were used with slight modification. Result: The average number of drugs per encounter was 2.6. The percentage of drugs prescribed by generic names and from the essential medicine list was 60% and 80.9%, respectively. The prescriptions encounters with antibiotics and injections were 58% and 4.2%, respectively. The average consultation and dispensing time were 3.6 min and 54.4 s, respectively. The percentage of drugs actually dispensed was 76.6%. Only half of the patients knew the correct dose of the dispensed drug and no adequate labeling at all. The majority of dispensers were intern nursing students (42%), and all prescribers were medical officers. Ten out of 12 primary healthcare centers had a copy of EML. The availability of key drugs in primary healthcare centers was incomplete (64.7%). Conclusion: The observed values for all World Health Organization indicators deviated from the optimal range. Patient care provided by health facilities was insufficient and thus an effective intervention program for the promotion of rational drug use practice is recommended.


Author(s):  
Eko Prasetio ◽  
Wahyu Utami ◽  
Zulhabri Othman ◽  
Ari Wardani ◽  
Abdul Rahem ◽  
...  

AbstractBackgroundThe Government of Indonesia has put in place many interventions for rationalizing drug use at all levels of the health services including in primary care centers (puskesmas). One of the programs for the rational use of drugs at the puskesmas is the monitoring and evaluation of drug use conducted by pharmacists. The purpose of this research was to evaluate the rationality of drug use in Pamekasan puskesmas that use World Health Organization (WHO) prescribing indicators and to find the difference in the percentage of rationality of drug use between puskesmas in Pamekasan.MethodsThis study reviewed official documents considering reporting of rational drug use. The documents were obtained from the district health office or from the public domain from 2014 to 2018. Data were then collated, extracted, and presented as frequencies.ResultsThe percentage prescribed for antibiotics for acute respiratory infection (ARI) non-pneumonia was 47.27% and percentage prescribing antibiotic drugs in a non-specific diarrhea was 59.85%. The percentage prescribed for injection was 36.15%. The average number of drugs prescribed per treatment was 2.61.ConclusionsThe majority of WHO guidelines stated that prescribing indicators were not met by the puskesmas in Pamekasan, except for the parameters for the average number of drugs prescribed per consultation. This shows an alarming clarion call for the local healthcare stakeholders to improve such situations.


2020 ◽  
Vol 5 (2) ◽  
pp. 1076-1081
Author(s):  
Bajarang Prasad Sah ◽  
Deepak Paudel ◽  
Deependra Prasad Sarraf

Introduction: Assessment of drug utilization pattern using the World Health Organization (WHO) prescribing indicators is important to promote rational drug therapy.It needs to be evaluated periodically to obtain information about drug utilization pattern, to detect early signals of irrational use of drugs and to provide feedback to prescribers. Objective: The objective of the present study was to assess the drug prescribing patterns in the Otorhinolaryngology OPD based on the WHO prescribing indicators. Methodology: A cross-sectional study was conducted among 148 outpatients at Otorhinolaryngology and HNS department of B.P. Koirala Institute of Health Sciences for six month duration. Patients aged 18 years and above and prescribed at least one drug were enrolled. Medical case sheets of the every fifth patients visiting the OPD were reviewed to collect the relevant data on a self-designed proforma. Descriptive statistics and WHO prescribing indicators were calculated using SPSS version 11.0. The study was approved by Institutional Review Committee, B.P. Koirala Institute of Health Sciences Results: A total of 322 drugs were prescribed to 148 patients. Most of the drugs were prescribe through oral route (69.3%). Levocetrizine (10.6%) was the commonest prescribed drug followed by Ibuprofen+Paracetamol (10.2%) and Pantoprazole (10.2%). Among systemic antibiotics, Amoxicillin+Clavulanic acid (35.9%) was the most frequently prescribed followed by Cefixime (12.8%) and Levofloxacin (12.8%). Ofloxacin + Dexamethasone (22.9%) was the most frequently prescribed topical drug followed by Mometasone (17.7%). The average number of drugs prescribed per encounter or mean was 2.2 (range 1-5). The percentage of encounters in which an antibiotic was prescribed was 33.2%. The percentage of drugs prescribed by generic name and from National List of Essential Medicine (NLEM) was 28% and 31.9% respectively. Conclusions: The drug utilization pattern did not comply with the most of the WHO prescribing indicators. The average number of drug per prescription was higher than recommended by WHO, generic prescribing was remarkably lower and prescribing from NLEM was also low.


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