scholarly journals Aural polyp with facial asymmetry in an unfortunate infant

2021 ◽  
Vol 16 (1) ◽  
pp. 133-135
Author(s):  
Farah Syahida Zubir ◽  
Jeyasakthy Saniasiaya ◽  
Haslinda Abdul Gani
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Temporal Bone ◽  
Early Treatment ◽  
Pediatric Patients ◽  
Facial Asymmetry ◽  
Ear Infection ◽  
Aural Polyp ◽  
History Of

Temporal bone rhabdomyosarcoma is an aggressive entity that simulates chronic otitis ear infection. It is the most common soft tissue sarcoma amongst pediatric patients. Herein, we would like to report a case of temporal bone rhabdomyosarcoma involving a 2-year-old boy who presented with a one-month history of otorrhea with facial asymmetry. Early treatment led to remission of this severe neoplasm.

scholarly journals Recurrent Episodic Foot-Drop Following Surgery to the Thigh

Sarcoma ◽  
2000 ◽  
Vol 4 (4) ◽  
pp. 183-184 ◽  
Author(s):  
Srinivas Maiya ◽  
Simon Tan ◽  
Robert J. Grimer
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Case History ◽  
Surgical Excision ◽  
Left Thigh ◽  
Foot Drop ◽  
Complete Relief ◽  
History Of

Subject.We present the case history of a 47-year-old lady who, 10 months following excision of a soft tissue sarcoma from the left thigh, was struck with recurrent episodes of foot drop.Discussion.The curious phenomenon of recurrent foot drop was found to be secondary to pressure symptoms from a tense seroma of the thigh. She underwent surgical excision of the sac and had immediate and complete relief of symptoms.

scholarly journals A Clinicopathological Analysis of Soft Tissue Sarcoma with Telangiectatic Changes

Sarcoma ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Hiroshi Kobayashi ◽  
Keisuke Ae ◽  
Taisuke Tanizawa ◽  
Tabu Gokita ◽  
Noriko Motoi ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Tumor Size ◽  
Epithelioid Sarcoma ◽  
Needle Aspiration ◽  
Nerve Sheath Tumor ◽  
Subsequent Recovery ◽  
Pleomorphic Sarcoma ◽  
History Of ◽  
Mri Characteristics

Background. Soft tissue sarcoma with a hemorrhagic component that cannot be easily diagnosed by needle biopsy is defined here as soft tissue sarcoma with telangiectatic changes (STST).Methods. We retrospectively reviewed clinicopathological data of STST from 14 out of 784 patients (prevalence: 1.8%) with soft tissue sarcoma.Results. Tumors were found mostly in the lower leg. Histological diagnoses were undifferentiated pleomorphic sarcoma (n=5), synovial sarcoma (n=5), epithelioid sarcoma (n=2), and malignant peripheral nerve sheath tumor and fibrosarcoma (n=1). No history of trauma to the tumor site was recorded in any patient. Needle aspiration transiently reduced the tumor volume, but subsequent recovery of tumor size was observed in all cases. Out of 14 patients, 9 presented with a painful mass. MRI characteristics included intratumoral nodules (64.3%). The local recurrence rate was 14.3%, and the 2-year event-free survival rate was poorer (50%) than that of most sarcomas.Conclusions. STST is unique in its clinicopathological presentation. Painful hematomas without a trauma history, intratumoral nodules within a large hemorrhagic component, and subsequent recovery of tumor size after aspiration are indicative of the presence of STST.

scholarly journals Smoking and Family Cancer History Are Associated With Sarcomas in A Japanese Population Study

2020 ◽  
Author(s):  
Yoshihiro Araki ◽  
Norio Yamamoto ◽  
Yoshikazu Tanzawa ◽  
Takahiro Higashi ◽  
Katsuhiro Hayashi ◽  
...  
Keyword(s):  
Family History ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Smoking Habit ◽  
Soft Tissue Sarcomas ◽  
High Grade ◽  
Cancer History ◽  
Family Cancer History ◽  
History Of ◽  
History Of Cancer

Abstract Background: Sarcoma is a rare cancer, and it is also the cause of the development of various kinds of sarcomas, such as gene abnormalities, which has recently becoming evident due to advances of genetic testing. The approach to solve the origin of diseases is essential to elucidate both the external environmental factors and the internal genetic factors. However, the lifestyle habits, lifestyle-related diseases, personal and family cancer history of sarcoma patients remain unclear.Methods: A total of 1320 sarcoma patients were enrolled in this study. A questionnaire on lifestyle habits, life-style diseases, and the patient’s personal and family cancer history was completed at presentation. A total of 1320 controls were selected by propensity score matching for age and gender. Smoking, drinking, obesity, hypertension, dyslipidemia and diabetes mellitus were compared. In addition, we investigated the incidence of a personal and family cancer history in sarcoma patients. Results: A smoking habit was the only independent risk factor for high-grade soft tissue sarcoma development in adults ≥20 years old (n=952), excluding low-grade and intermediate malignant soft tissue tumors (Odds ratio [OR], 2.45; 95% confidence interval [CI] 1.88-3.20, p<0.001). The ORs of high-grade liposarcoma and undifferentiated pleomorphic sarcoma (UPS) were 2.56 and 3.00, respectively. Eight percent of sarcoma patients had a personal history of another cancer. Thirty percent of soft tissue sarcoma patients had a family history of cancer in a first-degree relatives (malignant peripheral nerve sheath tumor, 52%; leiomyosarcoma, 46%). Conclusions: We confirmed that a smoking habit were associated with the development of high-grade soft tissue sarcomas. A family history of cancer might be associated with certain soft tissue sarcomas, but a further investigation will be necessary.

Treatment of Unilateral Buccal Crossbites in the Primary, Early Mixed, and Permanent Dentitions: Case Reports

2007 ◽  
Vol 31 (3) ◽  
pp. 214-218 ◽  
Author(s):  
Roberto Valencia
Keyword(s):  
Early Treatment ◽  
Pediatric Patients ◽  
Case Reports ◽  
Facial Asymmetry ◽  
Arch Width ◽  
Clinical Cases

It is important to recognize the development of an arch-width problem in pediatric patients and to determine the best time to treat it. One of these conditions is the posterior (buccal) crossbite where one may also find an exaggerated overjet, caused by maxillary excess, and/or mandibular width deficiency. One may also find a mandibular midline deviation on the side of the crossbite, creating a long-term orthopedic problem with a mild facial asymmetry. When correction of this condition is attempted in adulthood, poor results can be expected, making this the most important reason for early treatment. Six clinical cases are presented, along with the mechanics performed in both arches

Pulmonary nodules discovered during the initial evaluation of pediatric patients with bone and soft-tissue sarcoma

2008 ◽  
Vol 50 (6) ◽  
pp. 1147-1153 ◽  
Author(s):  
Michael J. Absalon ◽  
M. Beth McCarville ◽  
Tiebin Liu ◽  
Victor M. Santana ◽  
Najat C. Daw ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Pediatric Patients ◽  
Pulmonary Nodules ◽  
Initial Evaluation

scholarly journals Effective palliative treatment of recurrent soft tissue sarcoma in a dog using imatinib mesylate (Gleevec®)

2018 ◽  
Vol 63 (No. 11) ◽  
pp. 532-536
Author(s):  
G.H. Kim ◽  
J.H. Kim
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Surgical Resection ◽  
Partial Remission ◽  
Palliative Treatment ◽  
Metronomic Chemotherapy ◽  
Imatinib Treatment ◽  
Second Surgery ◽  
History Of ◽  
Yorkshire Terrier

A 14-year-old neutered female Yorkshire terrier presented with a rapidly growing gluteal mass. There was a history of surgical resection of a mass diagnosed as a grade two soft tissue sarcoma in the same region a year earlier. The second mass was surgically excised and histopathologically diagnosed as grade two soft tissue sarcoma. A further relapse occurred six months after the second surgery. On that occasion, the dog was treated with metronomic chemotherapy consisting of cyclophosphamide and piroxicam, which failed to adequately control the disease and the mass increased 2.5-fold in size in three weeks. Imatinib treatment was started, after which there was a 62% reduction in the size of the mass. The patient has remained in partial remission for five months. To the authors’ knowledge, this is the first report on the use of imatinib to treat canine soft tissue sarcoma. Imatinib might be a useful treatment for soft tissue sarcoma that recurs after surgical resection.

scholarly journals Neoadjuvant and adjuvant doxorubicin chemotherapy in a case of feline soft tissue sarcoma

2019 ◽  
Vol 5 (2) ◽  
pp. 205511691985787
Author(s):  
Filippo Torrigiani ◽  
Giorgio Romanelli ◽  
Paola Roccabianca ◽  
Elisabetta Treggiari
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Surgical Excision ◽  
Mesenchymal Tumour ◽  
Tissue Mass ◽  
History Of ◽  
Local Tumour ◽  
The Right ◽  
Slow Growing

Case summary A 7-year old male neutered domestic shorthair cat was presented with a 2 month history of a slow-growing mass on the right zygomatic area. A CT scan revealed a soft tissue mass in the right zygomatic region with no alterations of the underlying bone and features of local invasiveness. Cytology was suggestive of a mesenchymal tumour and histopathology from an incisional biopsy was consistent with a soft tissue sarcoma (STS). The cat was treated with neoadjuvant intravenous doxorubicin chemotherapy at a dose of 25 mg/m2, every two weeks. The patient experienced a partial response and underwent surgical excision of the tumour. Doxorubicin was continued as an adjuvant treatment for three further chemotherapy sessions, at a dose of 25 mg/m2 every 21 days. Local tumour recurrence was detected on clinical examination and cytologically confirmed 259 days following surgery. Relevance and novel information Treatment with neoadjuvant doxorubicin can be considered in cases of inoperable STSs in order to cytoreduce the tumour and improve the chances of achieving complete surgical margins. The role of adjuvant chemotherapy in this setting remains unclear.

Clinical Features and Outcome of Initially Unresected Nonmetastatic Pediatric Nonrhabdomyosarcoma Soft Tissue Sarcoma

2002 ◽  
Vol 20 (15) ◽  
pp. 3225-3235 ◽  
Author(s):  
Sheri L. Spunt ◽  
D. Ashley Hill ◽  
Alison M. Motosue ◽  
Catherine A. Billups ◽  
Alvida M. Cain ◽  
...  
Keyword(s):  
High Risk ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Neoadjuvant Therapy ◽  
Clinical Features ◽  
Pediatric Patients ◽  
Residual Tumor ◽  
Response To Therapy ◽  
Outcome Analysis ◽  
Limiting Factor

PURPOSE: To describe the clinical features, response to therapy, and outcome of pediatric patients with initially unresected nonmetastatic nonrhabdomyosarcoma soft tissue sarcoma (NRSTS). PATIENTS AND METHODS: We retrospectively reviewed the presenting clinical features and tumor characteristics of all 40 pediatric patients with initially unresected nonmetastatic NRSTS who were seen at our institution between March 1962 and December 1996. A subset of 27 patients for whom complete treatment information was available was analyzed to determine whether response to therapy was associated with local disease control and event-free and overall survival. RESULTS: More than 70% of the 40 patients had tumors with high-risk features (tumor size > 5 cm, high grade, invasiveness). For the 27 patients included in the outcome analysis, 5-year event-free survival and survival estimates were 33% ± 9% and 56% ± 10%, respectively. Ten (37%) of these patients had a complete or partial response to neoadjuvant chemotherapy and/or radiotherapy, and only two of the 10 had residual tumor after surgery. Combined chemotherapy and radiotherapy seemed more effective than either modality alone in inducing a response, but the response to neoadjuvant therapy did not predict outcome. Most treatment failures were local, and postrelapse survival was poor (19% ± 10%). CONCLUSION: Initially unresected NRSTS constitutes a unique subgroup of pediatric sarcomas that commonly present with high-risk features and respond poorly to neoadjuvant therapy. Only about one third of patients treated with multimodal therapy remain disease-free, and local control is the major limiting factor in achieving cure. More effective risk-directed treatments are needed for this unique subgroup of patients.

scholarly journals Capillary Hemangioma of the Temporal Bone

2017 ◽  
Vol 32 (1) ◽  
pp. 37-40
Author(s):  
Jose Z. Fernando ◽  
Rosario R. Ricalde
Keyword(s):  
Temporal Bone ◽  
Bone Erosion ◽  
Recurrent Infection ◽  
Punch Biopsy ◽  
Capillary Hemangioma ◽  
Suppurative Otitis Media ◽  
Aural Polyp ◽  
Keywords Hemangioma ◽  
History Of ◽  
The Right

Objective: To discuss a rare case of temporal bone capillary hemangioma, and its diagnosis and management. Methods:             Design:           Case Report             Setting:           Tertiary Government Hospital             Patient:           One Results: A 44-year old woman with a history of on-and-off right ear discharge, tinnitus and decreased hearing, and a pinkish, smooth-surfaced, non-friable, non-pulsating mass occluding the right external auditory canal, was initially treated for chronic suppurative otitis media with aural polyp. A punch biopsy due to persistence of disease despite medical treatment revealed capillary hemangioma.  She underwent canal wall down mastoidectomy with obliteration to completely resect the tumor. Conclusion: Capillary hemangiomas of the temporal bone are benign lesions that may lead to complications such as bone erosion, hearing loss, recurrent infection and bleeding if left untreated. Surgery remains the ideal treatment, and recurrence is rare and the prognosis is good if resection is complete. Keywords: Hemangioma, capillary hemangioma, temporal bone, middle ear  

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