Uncertainty assessment in subsurface modeling: considering geobody shape and connectivity in complex systems.

Author(s):  
Pauline Collon ◽  
Guillaume Rongier ◽  
Marion Parquer ◽  
Nicolas Clausolles ◽  
Guillaume Caumon

<p>Modeling the subsurface is a complex task because the data scarcity leads to ambiguous interpretations. As a result, subsurface models are prone to many uncertainties, which can be accounted for by stochastically simulating a large set of possible models. These models are constrained by the data (of various resolution and types), but also by geological knowledge and concepts. Integrating the latter in simulation methods emerges as a key point to reduce uncertainties, although it adds another layer of complexity to the modeling process. In this presentation, I focus on two different geological contexts characterized by specific geobody shapes and connectivity: channelized systems and salt tectonics.</p><p>Channelized systems are, indeed, characterized by elongated and sinuous structures, the channels, which evolve through time by continuous lateral and vertical migrations, and abrupt events like avulsion or meander cut-offs. The combination of erosion and deposition processes is an additional source of complexity in the sedimentary records. When considering the 3D reconstruction of channelized systems, honoring data while reproducing the complex spatial architecture of these structures - so their specific connectivity - remains challenging. The various methods we have recently developed can now be combined to achieve such a goal: (i) single channels or channel parts (for avulsion) can be simulated consistently with well-data, probability cubes, or confinement thanks to a method based on Lindenmayer systems; (ii) from a channel path, consistent 3D architectures can be generated with a reverse-time channel migration approach (ChaRMigS) handling the observed abandoned meanders; (iii) to honor well data within this reverse-time reconstruction, the stochastic simulation of abandoned meanders and avulsions offers interesting solutions. The impact of such modelling methodology on connectivity reproduction has been demonstrated using static criteria, and a flow-based evaluation constitutes an obvious next step.</p><p>In the case of salt tectonics, one difficulty comes from the highly convoluted shapes taken by salt bodies, incompatible with the hypothesis of minimal surface classically used in geomodeling methods. To tackle this issue, we have developed a dedicated method to stochastically generate various salt envelopes in a pre-defined uncertainty zone. Simulations of welds, i.e. surfaces (or most often thin volumes) resulting from the removal of salt from a former layer or diapir stage, also allow us to reproduce topological singularities between salt and the surrounding sediments. Welds connect the different salt volumes, which let us recover a more geologically-consistent representation of such complex systems. The present method is still in its early days, and further improvements need to be undertaken to fully integrate the diversity of structures actually observed in the field.</p>

Author(s):  
Rolando Leiva ◽  
Lise Rochaix ◽  
Noémie Kiefer ◽  
Jean-Claude K. Dupont

AbstractPurpose This study investigates the impact of an intensive case management program on sick leave days, permanent work incapacity levels and treatment costs for severe vocational injuries set up by the French National Insurance Fund in five health insurance districts. Methods The method employed relies on a four-step matching procedure combining Coarsened Exact Matching and Propensity Score Matching, based on an original administrative dataset. Average Treatment effects on the Treated were estimated using a parametric model with a large set of covariates. Results After one-year follow-up, workers in the treatment group had higher sickness absence rates, with 22 extra days, and the program led to 2.7 (95% CI 2.3–3.1) times more diagnoses of permanent work incapacity in the treatment group. With an estimated yearly operational cost of 2,722 € per treated worker, the average total extra treatment cost was 4,569 € for treated workers, which corresponds to a cost increase of 29.2% for the insurance fund. Conclusions The higher costs found for the treatment group are mainly due to longer sick leave duration for the moderate severity group, implying higher cash transfers in the form of one-off indemnities. Even though workers in the treated group have more diagnoses of permanent work incapacity, the difference of severity between groups is small. Our results on longer sick leave duration are partly to be explained by interactions between the case managers and the occupational physicians that encouraged patients to stay longer off-work for better recovery, despite the higher costs that this represented for the insurance fund and the well-documented adverse side effects of longer periods off-work.


2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Jessie Colin ◽  
Domenico Libri ◽  
Odil Porrua

Recent studies on yeast transcriptome have revealed the presence of a large set of RNA polymerase II transcripts mapping to intergenic and antisense regions or overlapping canonical genes. Most of these ncRNAs (ncRNAs) are subject to termination by the Nrd1-dependent pathway and rapid degradation by the nuclear exosome and have been dubbed cryptic unstable transcripts (CUTs). CUTs are often considered as by-products of transcriptional noise, but in an increasing number of cases they play a central role in the control of gene expression. Regulatory mechanisms involving expression of a CUT are diverse and include attenuation, transcriptional interference, and alternative transcription start site choice. This review focuses on the impact of cryptic transcription on gene expression, describes the role of the Nrd1-complex as the main actor in preventing nonfunctional and potentially harmful transcription, and details a few systems where expression of a CUT has an essential regulatory function. We also summarize the most recent studies concerning other types of ncRNAs and their possible role in regulation.


Author(s):  
Amin Moniri-Morad ◽  
Mohammad Pourgol-Mohammad ◽  
Hamid Aghababaei ◽  
Javad Sattarvand

Operational heterogeneity and harsh environment lead to major variations in production system performance and safety. Traditional probabilistic model is dealt with time-to-event data analysis, which does not have the capability of quantifying and simulation of these types of complexities. This research proposes an integrated methodology for analyzing the impact of dominant explanatory variables on the complex system reliability. A flexible parametric proportional hazards model is developed by focusing on standard parametric Cox regression model for reliability evaluation in complex systems. To achieve this, natural cubic splines are utilized to create a smooth and flexible baseline hazards function where the standard parametric distribution functions do not fit into the failure data set. A real case study is considered to evaluate the reliability for multi-component mechanical systems such as mining equipment. Different operational and environmental explanatory variables are chosen for the analysis process. Research findings revealed that precise estimation of the baseline hazards function is a major part of the reliability evaluation in heterogeneous environment. It is concluded that an appropriate maintenance strategy potentially mitigate the equipment failure intensity.


2019 ◽  
Author(s):  
Raphael Leman ◽  
Hélène Tubeuf ◽  
Sabine Raad ◽  
Isabelle Tournier ◽  
Céline Derambure ◽  
...  

Abstract Background: Branch points (BPs) map within short motifs upstream of acceptor splice sites (3’ss) and are essential for splicing of pre-mature mRNA. Several BP-dedicated bioinformatics tools, including HSF, SVM-BPfinder, BPP, Branchpointer, LaBranchoR and RNABPS were developed during the last decade. Here, we evaluated their capability to detect the position of BPs, and also to predict the impact on splicing of variants occurring upstream of 3’ss. Results: We used a large set of constitutive and alternative human 3’ss collected from Ensembl (n = 264,787 3’ss) and from in-house RNAseq experiments (n = 51,986 3’ss). We also gathered an unprecedented collection of functional splicing data for 120 variants (62 unpublished) occurring in BP areas of disease-causing genes. Branchpointer showed the best performance to detect the relevant BPs upstream of constitutive and alternative 3’ss (99.48 % and 65.84 % accuracies, respectively). For variants occurring in a BP area, BPP emerged as having the best performance to predict effects on mRNA splicing, with an accuracy of 89.17 %. Conclusions: Our investigations revealed that Branchpointer was optimal to detect BPs upstream of 3’ss, and that BPP was most relevant to predict splicing alteration due to variants in the BP area. Keywords: Branch Point, Prediction, RNA, Benchmark, HSF, SVM-BPfinder, BPP, Branchpointer, LaBranchoR, RNABPS, Variants


2018 ◽  
Vol 35 (1) ◽  
pp. 25-43
Author(s):  
Florian Unbehaun ◽  
Franz Fuerst

Purpose This study aims to assess the impact of location on capitalization rates and risk premia. Design/methodology/approach Using a transaction-based data series for the five largest office markets in Germany from 2005 to 2015, regression analysis is performed to account for a large set of asset-level drivers such as location, age and size and time-varying macro-level drivers. Findings Location is found to be a key determinant of cap rates and risk premia. CBD locations are found to attract lower cap rates and lower risk premia in three of the five largest markets in Germany. Interestingly, this effect is not found in the non-CBD locations of these markets, suggesting that the lower perceived risk associated with these large markets is restricted to a relatively small area within these markets that are reputed to be safe investments. Research limitations/implications The findings imply that investors view properties in peripheral urban locations as imperfect substitutes for CBD properties. Further analysis also shows that these risk premia are not uniformly applied across real estate asset types. The CBD risk effect is particularly pronounced for office and retail assets, apparently considered “prime” investments within the central locations. Originality/value This is one of the first empirical studies of the risk implications of peripheral commercial real estate locations. It is also one of the first large-scale cap rate analyses of the German commercial real estate market. The results demonstrate that risk perceptions of investors have a distinct spatial dimension.


2021 ◽  
Author(s):  
Hala Alqatari ◽  
Thierry-Laurent Tonellot ◽  
Mohammed Mubarak

Abstract This work presents a full waveform sonic (FWS) dataset processing to generate high-resolution images of the near-borehole area. The dataset was acquired in a nearly horizontal well over a distance of 5400 feet. Multiple formation boundaries can be identified on the final image and tracked at up to 200 feet deep, along the wellbore's trajectory. We first present a new preprocessing sequence to prepare the sonic data for imaging. This sequence leverages denoising algorithms used in conventional surface seismic data processing to remove unwanted components of the recorded data that could harm the imaging results. We then apply a reverse time migration algorithm to the data at different processing stages to assess the impact of the main processing steps on the final image.


2021 ◽  
Author(s):  
Pavlo Kuzmenko ◽  
Viktor Buhrii ◽  
Carlo D'Aguanno ◽  
Viktor Maliar ◽  
Hrigorii Kashuba ◽  
...  

Abstract Processing of the seismic data acquired in areas of complex geology of the Dnieper-Donets basin, characterized by the salt tectonics, requires special attention to the salt dome interpretation. For this purpose, Kirchhoff Depth Imaging and Reverse Time Migration (RTM) were applied and compared. This is the first such experience in the Dnieper-Donets basin. According to international experience, RTM is the most accurate seismic imaging method for steep and vertical geological (acoustic contrast) boundaries. Application of the RTM on 3D WAZ land data is a great challenge in Dnieper-Donets Basin because of the poor quality of the data with a low signal-to-noise ratio and irregular spatial sampling due to seismic acquisition gaps and missing traces. The RTM algorithm requires data, organized to native positions of seismic shots. For KPSDM we used regularized data after 5D interpolation. This affects the result for near salt reflection. The analysis of KPSDM and RTM results for the two areas revealed the same features. RTM seismic data looked more smoothed, but for steeply dipping reflections, lateral continuity of reflections was much improved. The upper part (1000 m) of the RTM has shadow zones caused by low fold. Other differences between Kirchhoff data and RTM are in the spectral content, as the former is characterized by the full range of seismic frequency spectrum. Conversely, beneath the salt, the RTM has reflections with steep dips which are not observed on the KPSDM. It is possible to identify new prospects using the RTM seismic image. Reverse Time Migration of 3D seismic data has shown geologically consistent results and has the potential to identify undiscovered hydrocarbon traps and to improve salt flank delineation in the complex geology of the Dnieper-Donets Basin's salt domes.


2019 ◽  
Vol 38 (8) ◽  
pp. 610-616
Author(s):  
Yun Wei ◽  
Hua Chen ◽  
Senqing Hu ◽  
Peipei Deng ◽  
Yongdeng Xiao ◽  
...  

A new broadband wide-azimuth towed-streamer (WATS) survey was acquired to better resolve reservoir compartments in a shallow-water region of the East China Sea. To offset the shortcomings of narrow-azimuth acquisition along the strike direction, two vessels were added side-by-side as additional source vessels to form the WATS acquisition geometry for this survey. This WATS acquisition was much sparser than typical WATS surveys used in deepwater environments due to its one-sided configuration. The combination of sparse acquisition, shallow water, and deep targets set the challenge of how to optimally reveal the potential of side-gun data to improve the final image. Three-dimensional effects and severe aliasing in the crossline direction pose significant challenges for side-gun data processing. We present a comprehensive workflow to resolve these challenges consisting of 3D deghosting, 3D model-based water-layer demultiple, 3D surface-related multiple elimination, and 4D regularization for sparse and shallow-water wide-azimuth data. A tilted orthorhombic velocity model is built with better constraints from the wide-azimuth data, leading to improved fault positioning and imaging. Side-gun data clearly enhance the final target reservoir image and tie better with well data due to improved illumination. A new channel is discovered based on interpretation from the inverted VP/VS, explaining the previous incorrect prediction for one failed well that was drilled into a thinner and shallower channel unconnected to the main reservoir. An analysis of the impact of side-gun data from different offsets and azimuths shows that better azimuthal distribution within middle offset ranges had a more significant impact than far offsets in the final image of this survey. This information provides valuable reference in similar geologic conditions for future acquisition designs.


Tectonics ◽  
2019 ◽  
Vol 38 (4) ◽  
pp. 1466-1488 ◽  
Author(s):  
Leonardo M. Pichel ◽  
Emma Finch ◽  
Rob L. Gawthorpe

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