BEHAVIOR OF DIFFERENT IMAGE CLASSIFIERS WITHIN A BROAD DOMAIN

2009 ◽  
Keyword(s):  
Broad Domain

The Hormonal Underpinnings of Sexual Communication

2020 ◽  
pp. 234-260
Author(s):  
Amanda Denes ◽  
Anuraj Dhillon ◽  
Ambyre L. P. Ponivas ◽  
Kara L. Winkler
Keyword(s):  
Interpersonal Relationships ◽  
Sexual Communication ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Communication Research ◽  
Future Directions ◽  
Oxytocin Receptor Gene ◽  
Broad Domain ◽  
Relational Outcomes

Sexual communication is a pivotal part of interpersonal relationships; recent research reveals associations between sexual communication and various relational outcomes. Within the broad domain of sexual communication, current scholarship specifically addresses the role of postsex communication in relationships and its links to physiological and genetic markers. Given these advancements, the present chapter offers an overview of research linking physiology, hormones, and genes to communication after sexual activity. The chapter first presents reviews of two key hormones in sexual communication research: testosterone (T) and oxytocin (O). The oxytocin receptor gene and its link to social behavior broadly, and sexual behavior specifically, is also explored. The chapter then offers a review of several theories relevant to understanding the hormonal underpinnings of sexual communication, as well as future directions for research exploring sexual communication and physiology.

Reliability and Validity of a Simulation-based Acute Care Skills Assessment for Medical Students and Residents

2003 ◽  
Vol 99 (6) ◽  
pp. 1270-1280 ◽  
Author(s):  
John R. Boulet ◽  
David Murray ◽  
Joe Kras ◽  
Julie Woodhouse ◽  
John McAllister ◽  
...  
Keyword(s):  
Medical Students ◽  
Acute Care ◽  
Reliability And Validity ◽  
Faculty Members ◽  
First Year ◽  
Clinical Experiences ◽  
Critical Events ◽  
Simulation Based ◽  
Broad Domain ◽  
Simulation Exercises

Background Medical students and residents are expected to be able to manage a variety of critical events after training, but many of these individuals have limited clinical experiences in the diagnosis and treatment of these conditions. Life-sized mannequins that model critical events can be used to evaluate the skills required to manage and treat acute medical conditions. The purpose of this study was to develop and test simulation exercises and associated scoring methods that could be used to evaluate the acute care skills of final-year medical students and first-year residents. Methods The authors developed and tested 10 simulated acute care situations that clinical faculty at a major medical school expects graduating physicians to be able to recognize and treat at the conclusion of training. Forty medical students and residents participated in the evaluation of the exercises. Four faculty members scored the students/residents. Results The reliability of the simulation scores was moderate and was most strongly influenced by the choice and number of simulated encounters. The validity of the simulation scores was supported through comparisons of students'/residents' performances in relation to their clinical backgrounds and experience. Conclusion Acute care skills can be validly and reliably measured using a simulation technology. However, multiple simulated encounters, covering a broad domain, are needed to effectively and accurately estimate student/resident abilities in acute care settings.

Application of Modular Air-Tuned Damper System in High-Rise Buildings

2019 ◽  
Author(s):  
Sebastian Mendes ◽  
Zhi Zhang ◽  
Pierre Ghisbain ◽  
Marguerite Pinto ◽  
Elisabeth Malsch
Keyword(s):  
Cost Effective ◽  
Tuned Mass Dampers ◽  
Interior Space ◽  
High Rise ◽  
Complex Shapes ◽  
Dynamic Analyses ◽  
Broad Domain ◽  
Wind Events ◽  
Tuned Damper

<p>High-rise buildings are progressively being designed and constructed in increasingly slender and complex shapes. Consequently, excessive wind-induced vibrations of these structures are a growing serviceability concern due to their flexibility. Tuned mass dampers (TMDs) are regularly incorporated into high-rise buildings for mitigating excessive wind-induced vibrations. However, traditional TMDs are only effective over a narrow domain of frequencies, require an immense mass and occupy a significant volume of interior space. A novel modular air-tuned damper system was developed which is more cost-effective and flexible in distributing its mass throughout a building to make efficient use of unused space. Importantly, the air-tuned damper system is capable of being tuned across a broad domain of frequencies to more effectively alleviate wind-induced vibrations. This paper presents a case study demonstrating the performance of a high-rise building under 1- year and 10-year wind events whilst equipped with the air-tuned damper system. Dynamic analyses were performed for evaluating the reductions of the building’s lateral accelerations considering different air-tuned damper configurations. The performance of the building under the different damper configurations is discussed.</p>

Retinoic acid synthesis and hindbrain patterning in the mouse embryo

Development ◽  
2000 ◽  
Vol 127 (1) ◽  
pp. 75-85 ◽  
Author(s):  
K. Niederreither ◽  
J. Vermot ◽  
B. Schuhbaur ◽  
P. Chambon ◽  
P. Dolle
Keyword(s):  
Retinoic Acid ◽  
Neural Crest ◽  
Hox Genes ◽  
Receptor Gene ◽  
Acid Synthesis ◽  
Branchial Arch ◽  
Eph Receptor ◽  
Caudal Portion ◽  
Midbrain Region ◽  
Broad Domain

Targeted disruption of the murine retinaldehyde dehydrogenase 2 (Raldh2) gene precludes embryonic retinoic acid (RA) synthesis, leading to midgestational lethality (Niederreither, K., Subbarayan, V., Dolle, P. and Chambon, P. (1999). Nature Genet. 21, 444–448). We describe here the effects of this RA deficiency on the development of the hindbrain and associated neural crest. Morphological segmentation is impaired throughout the hindbrain of Raldh2−/− embryos, but its caudal portion becomes preferentially reduced in size during development. Specification of the midbrain region and of the rostralmost rhombomeres is apparently normal in the absence of RA synthesis. In contrast, marked alterations are seen throughout the caudal hindbrain of mutant embryos. Instead of being expressed in two alternate rhombomeres (r3 and r5), Krox20 is expressed in a single broad domain, correlating with an abnormal expansion of the r2-r3 marker Meis2. Instead of forming a defined r4, Hoxb1- and Wnt8A-expressing cells are scattered throughout the caudal hindbrain, whereas r5/r8 markers such as kreisler or group 3/4 Hox genes are undetectable or markedly downregulated. Lack of alternate Eph receptor gene expression could explain the failure to establish rhombomere boundaries. Increased apoptosis and altered migratory pathways of the posterior rhombencephalic neural crest cells are associated with impaired branchial arch morphogenesis in mutant embryos. We conclude that RA produced by the embryo is required to generate posterior cell fates in the developing mouse hindbrain, its absence leading to an abnormal r3 (and, to a lesser extent, r4) identity of the caudal hindbrain cells.

Affect-Sensitive Computer Systems

2018 ◽  
pp. 4124-4135
Author(s):  
Nik Thompson ◽  
Tanya McGill ◽  
David Murray
Keyword(s):  
Information Processing ◽  
Software Development ◽  
Human Computer Interaction ◽  
Rapid Growth ◽  
Affective Computing ◽  
Emotional State ◽  
Computer Systems ◽  
Theoretical Models ◽  
Computer Interfaces ◽  
Broad Domain

Affective computing is the broad domain encompassing all of the hardware, software and underlying theoretical models underpinning the development of affect sensitive computer systems. Such systems facilitate more intuitive, natural computer interfaces by enabling the communication of the user's emotional state. Despite rapid growth in recent years, affective computing is still an under-explored field, which holds promise to be a valuable direction for future software development. Human-computer interaction has traditionally been dominated by the information processing metaphor and as a result, interaction between the computer and the user is generally unidirectional and asymmetric. The next generation of computer interfaces aim to address this gap in communication and create interaction environments that support the motivational and affective goals of the user.

Sous-groupes dans le domaine des états-limites

1982 ◽  
Vol 27 (5) ◽  
pp. 390-396
Author(s):  
Michael H. Stone
Keyword(s):  
Early Life ◽  
Antidepressant Medication ◽  
Depressive Illness ◽  
Clinical Syndrome ◽  
Manic Depressive Illness ◽  
Manic Depressive ◽  
Affective Symptoms ◽  
Borderline Patients ◽  
Broad Domain ◽  
Dexamethasone Suppression

The currently most popular definitions of “borderline” are those of Kernberg, Gunderson and Spitzer (now incorporated into the DSM-III). The Kernberg criteria define a level of function (between “Neurotic” and “Psychotic”); the Gunderson criteria, a more narrowly circumscribed clinical syndrome, phenomenologically distinct from schizophrenia and from the psychoneuroses. The DSM-III criteria are derived from these and other sources and define a broad domain that includes the other usages of “borderline.” Even the narrower definitions of borderline describe a collection of conditions heterogeneous with respect to hereditary, constitutional and psychosocial factors. Genetic, biochemical and clinical research suggests the appropriateness of dividing the borderline domain into a variety of sub-types. The largest proportion of borderline cases are effective (with prominent depressive symptoms; occasionally, with cyclothymic or hypomanic symptoms). Of these, some show strong “endogenous” features, as well as family pedigrees of manic-depressive illness. This category includes many patients with anorexia nervosa or with agoraphobia. In others, the affective symptoms seem more related to severe psychosocial stresses in early life (including physical abuse, parental deprivation, or incest). Smaller proportions within the borderline domain are occupied by schizotypal cases (many with hereditary linkage to core schizophrenia), or by organic cases (including temporal lobe epilepsy, or minimal brain damage, giving rise to the “episodic dyscontrol” syndrome). Biochemical and nerophysiological markers that may be useful in distinguishing among the borderline subtypes include measure of platelet MA O-activity, of dexamethasone suppression, of R.E.M. latency, motion-sickness susceptibility and of average evoked response to photic stimulation. Attention to subtypes is important in considering optimal treatment for borderline patients. Not all respond to analytically-oriented psychotherapy alone. Those with severe affective symptoms often require antidepressant medication or lithium. Affectively ill borderlines usually have a better prognosis than schizotypals. In cases of episodic dyscontrol, anti-epileptic drugs may be useful.

Using the short Subscales of a Questionnaire to Assess Subcomponents with low Reliabilities: A Cautionary Note

2002 ◽  
Vol 90 (3_part_2) ◽  
pp. 1255-1256
Author(s):  
Ahmed Abdel-Khalek ◽  
David Lester
Keyword(s):  
College Students ◽  
Factor Analysis ◽  
Cautionary Note ◽  
Broad Domain ◽  
Personality Questionnaires

Some authors of personality questionnaires use factor analysis with the aim of constructing subcomponents to assess subsidiary traits within the broad domain tapped by the scale. However, these short subscales suffer from low reliabilities in most cases. The findings of using the Maudsley Obsessional–Compulsive Inventory in American ( n = 73) and Kuwaiti ( n = 87) college students justified the caution against using such short subscales with low reliabilities, inasmuch-as 7 out of the 8 alpha reliabilities were less than .69, ranged from .35 to .68, and the median was .56.

scholarly journals Lipid domain–dependent regulation of single-cell wound repair

2014 ◽  
Vol 25 (12) ◽  
pp. 1867-1876 ◽  
Author(s):  
Emily M. Vaughan ◽  
Jae-Sung You ◽  
Hoi-Ying Elsie Yu ◽  
Amber Lasek ◽  
Nicolas Vitale ◽  
...  
Keyword(s):  
Wound Repair ◽  
De Novo ◽  
Cell Damage ◽  
Healing Process ◽  
Lipid Domains ◽  
Damage Site ◽  
Lipid Domain ◽  
Broad Domain ◽  
Cortical Cytoskeleton

After damage, cells reseal their plasma membrane and repair the underlying cortical cytoskeleton. Although many different proteins have been implicated in cell repair, the potential role of specific lipids has not been explored. Here we report that cell damage elicits rapid formation of spatially organized lipid domains around the damage site, with different lipids concentrated in different domains as a result of both de novo synthesis and transport. One of these lipids—diacylglycerol (DAG)—rapidly accumulates in a broad domain that overlaps the zones of active Rho and Cdc42, GTPases that regulate repair of the cortical cytoskeleton. Formation of the DAG domain is required for Cdc42 and Rho activation and healing. Two DAG targets, protein kinase C (PKC) β and η, are recruited to cell wounds and play mutually antagonistic roles in the healing process: PKCβ participates in Rho and Cdc42 activation, whereas PKCη inhibits Rho and Cdc42 activation. The results reveal an unexpected diversity in subcellular lipid domains and the importance of such domains for a basic cellular process.

scholarly journals Broad domain generality in focal regions of frontal and parietal cortex

2013 ◽  
Vol 110 (41) ◽  
pp. 16616-16621 ◽  
Author(s):  
E. Fedorenko ◽  
J. Duncan ◽  
N. Kanwisher
Keyword(s):  
Parietal Cortex ◽  
Domain Generality ◽  
Broad Domain

scholarly journals Etyka biegłego rewidenta

2008 ◽  
Vol 4 ◽  
pp. 296-305
Author(s):  
Grażyna Voss
Keyword(s):  
Business Ethics ◽  
Strong Relation ◽  
Broad Domain ◽  
Personal Ethics ◽  
Environment Preservation

Business ethics is a broad domain. The legislative entity defines its practice as a moralbusiness (that is advisable and recommended). Moral qualifications assure the clearness of thelaws in the insurances, in the environment preservation, and in the honesty of banking system.There is a strong relation between the company’s ethics and the personal ethics of employees.It means that both the manager and the workers are responsible for the ethics. The choice of theemployees should take into account their style of life (and their characteristics) to promise theethics in the business.

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