scholarly journals PENGARUH BACAAN MUROTTAL AL-QUR’AN YANG DIPERDENGARKAN PADA PASIEN STROKE ISKEMIK AKUT TERHADAP LUARAN KLINIS

Author(s):  
Susi Ifati ◽  
Dodik Tugasworo ◽  
Dwi Pudjonarko

    THE EFFECT OF HOLY QUR’AN HEARING ON CLINICAL OUTCOMES IN ACUTE ISCHEMIC STROKEABSTRACTIntroduction: Qur’an recitation has a high spiritual and religious value and effect to Islam believer, and also has beautiful and regular tone, so that it is believed to be useful to cure various diseases. Depression and anxiety are common, and add to worsening outcomes of stroke. There was spiritual correlation between decreased emotional distress and depression associated with poor outcome of stroke. Qur’an recitation could be used as spiritual relaxation technique, thus improve the effect of mental health.Aims: To determine effect of Qur’an recitation audio on anxiety, depression and National Institute of Health Stroke Scale (NIHSS) in acute ischemic stroke in Medical Faculty of Diponegoro University/dr. Kariadi Hospital, Semarang, Central Java Indonesia.Method: This was an intended to treat research with randomized pretest-posttest with control group design. Subjects were acute ischemic stroke patients with onset less than 72 hours, divided into treatment and control groups. Treatment was carried out for 7 days by playing Juz ‘Amma Qur’an recitation through headphone twice a day for 30 minutes at 06.00 am and 06.00 pm. Demographic data, risk factors, and Hospital Anxiety and Depression Scale (HADS) and NIHSS before and after treatment were assessed. The correlation of HADS and NIHSS between treatment and control were analyzed with Chi-square/Fisher test. Multivariate analysis was used to analyzed other factors affecting clinical outcomes.Result: Forty subjects were randomized into treatment or control groups. There was significant correlation between listening Juz ‘Amma Qur’an recitation with improvement of anxiety HADS and NIHSS. There was no correlation with improvement of depression HADS. Logistic regression analysis showed improvement of NIHSS after listening Juz ‘Amma Qur’an recitation.Discussion: Listening to the Qur’an recitation improved anxiety symptoms, improved clinical outcomes by 9.025 times compared to controls in acute ischemic stroke, thus can be considered to support the recovery of stroke patients.Keywords: Acute ischemic stroke, HADS, NIHSS, Qur’an recitationABSTRAKPendahuluan: Bacaan Al-Qur’an memiliki nilai spiritualitas dan religiositas yang tinggi serta memberikan efek ketenangan selain nadanya indah dan teratur, sehingga dapat digunakan untuk penyembuhan berbagai penyakit. Depresi maupun ansietas sering terjadi pada stroke yang menambah perburukan luaran. Terdapat hubungan spiritual pada penurunan ansietas dan depresi yang dihubungkan dengan luaran stroke yang buruk. Bacaan Al-Qur’an dapat digunakan sebagai teknik relaksasi spiritual sehingga didapatkan efek meningkatkan kesehatan mental.Tujuan: Untuk mengetahui pengaruh murottal Al-Qur’an yang diperdengarkan pada pasien stroke iskemik akut terhadap luaran klinis neurologis menggunakan skor National Institute of Health Stroke Scale (NIHSS), gangguan depresi dan ansietas di Fakultas Kedokteran Universitas Diponegoro/RSUP dr. Kariadi, Semarang, Jawa Tengah, Indonesia.Metode: Penelitian ini merupakan penelitian perlakuan randomized pretest-posttest control group design. Subjek adalah pasien stroke iskemik akut awitan kurang 72 jam, dibagi menjadi kelompok perlakuan dan kontrol. Perlakuan dilaksanakan 7 hari dengan memperdengarkan murottal Al-Qur’an Juz ‘Amma melalui headphone sehari 2 kali, durasi30 menit pukul 06.00 dan 16.00. Data yang diambil meliputi data demografi, faktor risiko stroke serta penilaian Hospital Anxiety and Depression Scale (HADS), dan NIHSS sebelum dan setelah perlakuan. Pengaruh perlakuan terhadap HADS, NIHSS menggunakan uji Chi-square/Fisher. Faktor-faktor lain yang berpengaruh pada luaran klinis juga dianalisis secara multivariat.Hasil: Sebanyak 40 subjek dilakukan random alokasi sebagai kelompok perlakuan berjumlah 20 subjek dan kelompok kontrol berjumlah 20 subjek. Terdapat hubungan bermakna antara memperdengarkan murottal Al-Qur’an dengan perbaikan HADS ansietas, dan perbaikan NIHSS. Tidak terdapat hubungan antara memperdengarkan murottal Al-Qur’an dan perbaikan HADS depresi. Analisis logistik regresi menunjukkan, memperdengarkan murottal Al-Qur’an berpengaruh pada perbaikan NIHSS pasien stroke iskemik akut.Diskusi: Memperdengarkan murottal Al-Qur’an memperbaiki gejala ansietas, memperbaiki luaran klinis sebesar 9,025 kali dibanding kontrol pada stroke iskemik akut sehingga dapat dipertimbangkan untuk menunjang pemulihan pasien stroke.Kata kunci: Murottal Al-Qur’an, NIHSS, skor HADS, stroke iskemik akut 

2019 ◽  
Vol 39 (4) ◽  
pp. 245-255
Author(s):  
Yanny Octavia Sally Ride ◽  
Yusup Subagio Sutanto ◽  
Debree Septiawan

Background: Anxiolytic premedication can reduce anxiety, improving procedural tolerance, and reduce postbronchoscopic complications. There was ongoing debate about the safety of bronchoscopist-administered sedation. Alprazolam as a surgical premedication can reduce anxiety. Alprazolam can be used as an adjuvant analgesic, to reduce anxiety-related breathlessness, and to reduce coughing as adjuvant antitussive. The study aimed to evaluate the effectiveness of alprazolam in patients undergoing bronchoscopy. Methods: A clinical study with experimental quasi pre-post test control group design, using consecutive sampling was performed in patients with lung tumor undergoing bronchoscopy in dr.Moewardi Hospital from February to March 2019. The study subjects were divided in experimental (alprazolam) and control groups (without alprazolam). The Hospital Anxiety and Depression Scale (HADS), VAS for pain score, modified Borg score, and VAS for cough were measured in baseline, before, and after bronchoscopy. Results: Thirty two lung subjects were included in this study. The intervention groups showed decreased HADS score pre and post bronchoscopy (6.56±2.83 and 6.88±2.63), pain VAS scores (15.00±10.95 and 9.69±11.61), cough VAS score (11.56±8.89 and 27.19±17.89), and these were different significantly compared to control group. We found decreased mean of modified Borg in the study group though they were not significant compared to the control group. Conclusion: Alprazolam controlled anxiety, coughing, and pain in patients undergoing bronchoscopy. Alprazolam minimized breathlessness after bronchoscopy. (J Respir Indo. 2019; 39(4): 245-55)


2020 ◽  
Author(s):  
Jung-Won Choi ◽  
In Woo Ryoo ◽  
Jun Yeong Hong ◽  
Kyung-Yul Lee ◽  
Hyo Suk Nam ◽  
...  

Abstract Background: Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are associated with infirmity, vascular disease, and adverse cardiovascular risk factors. Currently, female sexual hormones are considered neuroprotective agents. The purpose of this study was to assess the role of sex hormones and the ratio of estradiol/testosterone (E/T) in patients with acute ischemic stroke (AIS).Methods: Between January 2011 and December 2016, 146 male patients with AIS and 152 age- and sex-matched control subjects were included in this study. Sex hormones, including estradiol, progesterone, and testosterone, were evaluated in the AIS patient and control groups. We analyzed the clinical and physiological levels of sex hormones and hormone ratios in these patients.Results: The E/T ratio was significantly elevated among patients in the stroke group compared to those in the control group (P = 0.001). Categorization of data into tertiles revealed that patients with the highest E/T ratio were more likely to have AIS [odds ratio (OR) 3.084; 95% Confidence interval (CI): 1.616-5.886; P < 0.001) compared with those in the first tertile. The E/T ratio was also an independent unfavorable outcome predictor with an adjusted OR of 1.167 (95% CI: 1.053-1.294; P = 0.003).Conclusions: These findings support the hypothesis that increased estradiol and reduced testosterone levels are associated with AIS in men.


2018 ◽  
Vol 3 (2) ◽  

Background: As one of the chronic conditions, stroke brings about important problems for the individual, their family and the society. Aim: This research was made in order to determine the effect of training given to stroke patient caregivers on their anxiety and depression levels. Methods: This experimental research with pretest-posttest control group was conducted in Neurology Clinic between July 2011 and July 2012. The experiment group of the research consisted of 31 stroke patient lying for the first time in the clinic and control group consisted of 33 stroke patients who lied in the clinic before and also care givers. The pretest data was collected by the patient and care giver introduction form prepared by the researchers starting from the week the patient was accepted to the clinic, Barthel Index and Hospital Anxiety and Depression Scale. Posttest data was collected by using all scales after discharge of patient (except introduction form). In the evaluation of the data percentage, average, chi-square was used and also t test was used in independent groups. Results: According to research results a significant difference could not be found between anxiety and depression points of experiment and control groups before training (p>0.05). In the evaluation made after the training it was determined that the anxiety and depression points of the caregivers decreased and the decreases were significant (p<0.001). Conclusions: As a result it was determined that the training given to care givers in the experiment group decreased their anxiety and depression levels. We can recommend that nurses participate in educations on the care of patients with stroke, provide education to caregivers and arrange workshops to increase their awareness on this issue.


2020 ◽  
Author(s):  
Jung-Won Choi ◽  
In Woo Ryoo ◽  
Jun Yeong Hong ◽  
Kyung-Yul Lee ◽  
Hyo Suk Nam ◽  
...  

Abstract Background: Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are associated with infirmity, vascular disease, and adverse cardiovascular risk factors. Currently, female sexual hormones are considered neuroprotective agents. The purpose of this study was to assess the role of sex hormones and the ratio of estradiol/testosterone (E/T) in patients with acute ischemic stroke (AIS). Methods: Between January 2011 and December 2016, 146 male patients with AIS and 152 age- and sex-matched control subjects were included in this study. Sex hormones, including estradiol, progesterone, and testosterone, were evaluated in the AIS patient and control groups. We analyzed the clinical and physiological levels of sex hormones and hormone ratios in these patients.Results: The E/T ratio was significantly elevated among patients in the stroke group compared to those in the control group (P = 0.001). Categorization of data into tertiles revealed that patients with the highest E/T ratio were more likely to have AIS [odds ratio (OR) 3.084; 95% Confidence interval (CI): 1.616-5.886; P < 0.001) compared with those in the first tertile. The E/T ratio was also an independent unfavorable outcome predictor with an adjusted OR of 1.167 (95% CI: 1.053-1.294; P = 0.003).Conclusions: These findings support the hypothesis that increased estradiol and reduced testosterone levels are associated with AIS in men.


2020 ◽  
Author(s):  
Jung-Won Choi ◽  
In Woo Ryoo ◽  
Jun Yeong Hong ◽  
Kyung-Yul Lee ◽  
Hyo Suk Nam ◽  
...  

Abstract Background: Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are associated with infirmity, vascular disease, and adverse cardiovascular risk factors. Currently, female sexual hormones are considered neuroprotective agents. The purpose of this study was to assess the role of sex hormones and the ratio of estradiol/testosterone (E/T) in patients with acute ischemic stroke (AIS). Methods: Between January 2011 and December 2016, 146 male patients with AIS and 152 age- and sex-matched control subjects were included in this study. Sex hormones, including estradiol, progesterone, and testosterone, were evaluated in the AIS patient and control groups. We analyzed the clinical and physiological levels of sex hormones and hormone ratios in these patients.Results: The E/T ratio was significantly elevated among patients in the stroke group compared to those in the control group (P = 0.001). Categorization of data into tertiles revealed that patients with the highest E/T ratio were more likely to have AIS [odds ratio (OR) 3.084; 95% Confidence interval (CI): 1.616-5.886; P < 0.001) compared with those in the first tertile. The E/T ratio was also an independent unfavorable outcome predictor with an adjusted OR of 1.167 (95% CI: 1.053-1.294; P = 0.003).Conclusions: These findings support the hypothesis that increased estradiol and reduced testosterone levels are associated with AIS in men.


BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jung-Won Choi ◽  
In Woo Ryoo ◽  
Jun Yeong Hong ◽  
Kyung-Yul Lee ◽  
Hyo Suk Nam ◽  
...  

Abstract Background Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are associated with infirmity, vascular disease, and adverse cardiovascular risk factors. Currently, female sexual hormones are considered neuroprotective agents. The purpose of this study was to assess the role of sex hormones and the ratio of estradiol/testosterone (E/T) in patients with acute ischemic stroke (AIS). Methods Between January 2011 and December 2016, 146 male patients with AIS and 152 age- and sex-matched control subjects were included in this study. Sex hormones, including estradiol, progesterone, and testosterone, were evaluated in the AIS patient and control groups. We analyzed the clinical and physiological levels of sex hormones and hormone ratios in these patients. Results The E/T ratio was significantly elevated among patients in the stroke group compared to those in the control group (P = 0.001). Categorization of data into tertiles revealed that patients with the highest E/T ratio were more likely to have AIS [odds ratio (OR) 3.084; 95% Confidence interval (CI): 1.616-5.886; P < 0.001) compared with those in the first tertile. The E/T ratio was also an independent unfavorable outcome predictor with an adjusted OR of 1.167 (95% CI: 1.053-1.294; P = 0.003). Conclusions These findings support the hypothesis that increased estradiol and reduced testosterone levels are associated with AIS in men.


Author(s):  
Tahereh Bahrami, MScN ◽  
Nahid Rejeh, PhD, MScN, BScN ◽  
Majideh Heravi-Karimooi, PhD, MScN, BScN ◽  
Seyed Davood Tadrisi, MScN ◽  
Mojtaba Vaismoradi, PhD, MScN, BScN

Background: Patients with cardiovascular diseases usually suffer from hospital anxiety and depression. Aim: This study aimed to investigate the effect of foot reflexology massage on anxiety and depression in female older adults suffering from acute coronary syndrome.Participants: Ninety older women with acute coronary syndrome were randomly assigned into intervention and control groups (n=45 in each group).Research Design: A randomized controlled trial.Intervention: The intervention and control groups received foot reflexology massage and routine care, respectively.Main Outcomes Measures: The levels of anxiety and depression were evaluated using the hospital’s anxiety and depression scale (HADS) before and immediately after foot reflexology massage.Results: Foot reflexology massage reduced both anxiety (F(1.44)=19.11, p = .001) and depression (F(1.44)=16.76, p = .001) in acute coronary patients relative to control patients. The intervention had a large effect on hospital anxiety and depression.Conclusions: Foot reflexology massage is an efficient and safe intervention for alleviating psychological responses among female older adults suffering from acute coronary syndrome during hospitalization.


2019 ◽  
Vol 39 (1) ◽  
pp. 21-30
Author(s):  
Teguh Budi Santosa ◽  
Yusup Subagio Sutanto ◽  
Debree Septiawan

Background: Patient’s comfort during bronchoscopy is important, as it affects its success and the whole outcome. The short comings of bronchoscopy with general anesthesia are long procedure, high cost, and its complication in respiratory failure patient’s. Hypnosis in various surgery procedures can reduce anxiety. Hypnosis can also be used as a therapy for shortness of breath and chronic cough. This study aimed to analyze the effectiveness of hypnotherapy in controling anxiety, breathing shortness a cough of patient’s undergoing bronchoscopy. Methods: This research is a clinical trial with a quasi-experimental design using the pretest-posttest control group approach using consecutive sampling was performed in patients with lung tumor undergoing bronchoscopy in dr. Moewardi Hospital from July to August 2018. The study subjects were randomized in to hypnotized and non-hypnotized (control groups). Scores of Hospital Anxiety and Depression Scale (HADS), modified Borg, and cough Visual Analog Scale (VAS) were measured before and after bronchoscopy. Results: Thirtyseven lung tumor patient’s undergoing bronchoscopy were included in our study. The intervention groups showed decreased HADS (6,68+8,28) and different significantly compared to control group (p


2020 ◽  
Author(s):  
Jung-Won Choi ◽  
In Woo Ryoo ◽  
Jun Yeong Hong ◽  
Kyung-Yul Lee ◽  
Hyo Suk Nam ◽  
...  

Abstract Background: Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are associated with infirmity, vascular disease, and adverse cardiovascular risk factors. Currently, female sexual hormones are considered neuroprotective agents. The purpose of this study was to assess the role of sex hormones and the ratio of estradiol/testosterone (E/T) in patients with acute ischemic stroke (AIS). Methods: Between January 2011 and December 2016, 146 male patients with AIS and 152 age- and sex-matched control subjects were included in this study. Sex hormones, including estradiol, progesterone, and testosterone, were evaluated in the AIS patient and control groups. We analyzed the clinical and physiological levels of sex hormones and hormone ratios in these patients.Results: The E/T ratio was significantly elevated among patients in the stroke group compared to those in the control group (P = 0.001). Categorization of data into tertiles revealed that patients with the highest E/T ratio were more likely to have AIS [odds ratio (OR) 3.084; 95% Confidence interval (CI): 1.616-5.886; P < 0.001) compared with those in the first tertile. The E/T ratio was also an independent unfavorable outcome predictor with an adjusted OR of 1.167 (95% CI: 1.053-1.294; P = 0.003).Conclusions: These findings support the hypothesis that increased estradiol and reduced testosterone levels are associated with AIS in men.


2021 ◽  
Vol 2 (1) ◽  
pp. 15-25
Author(s):  
Muhammad Anggun ◽  
Titik Kusumawinakhyu ◽  
Irma Finurina Mustikawati ◽  
Wiharto Wiharto

Hemodialysis is a routinely performed therapy on chronic kidney patients, leading to psychological problems among subjects who undergo hemodialysis, such as anxiety and depression. One of the efforts to overcome anxiety and depression is with the dhikr intervention. Dhikr presents hearts to remember and be obedient to Allah followed by the words and actions in various conditions.  Discover dhikr's influence on the level of anxiety and depression in patients on hemodialysis in  Purwokerto Islamic Hospital. It was a quantitative study using quasi experiment with a non-quivalent control group design. The number of samples was 12 subjects consisting of 6 subjects in the control group and six subjects in the intervention group with the purposive sampling technique. Instruments were used to measure anxiety and depression are the HADS ( Hospital Anxiety and Depression Scale ) before and after dhikr intervention as much as 12 times. Research is carried out in Hemodialysis Unit of  Purwokerto Islamic Hospital. Test statistics on research are used paired t-test and independent t-tests. This study showed a decrease in the mean level of anxiety from 5, 83 to 1.67 in the experimental group ( p = 0.003). The mean level of depression experienced a decline of 9, 67 becomes 4.67 on a group experiment ( p = 0.003). Dhikr reduces the level of anxiety and depression in hemodialysis patients at the Purwokerto Islamic Hospital.


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