Malassezia Species Associated Seborrheic Dermatitis and Its Comparison between HIV Positive and Negative Patients

Introduction: Malassezia yeasts are lipophilic organisms causing certain skin diseases. Seborrheic dermatitis (SD) is the second most common skin infection caused by Malassezia as well as in HIV/AIDS. Aim: To determine the frequency of association of Malassezia species in HIV infected and HIV non-infected patients with Seborrheic dermatitis. Materials and Methods: The prevalence of Seborrheic dermatitis is 5% in the general population. Hence a sample size of 80 was derived, 40 each of HIV seropositive and HIV seronegative adult patients clinically suspected of having Seborrheic Dermatitis. Specimens were collected by scraping and cellophane tape for KOH and Chicago Sky Blue (CSB) stain, and were cultured on Sabouraud’s dextrose agar. Data were analysed using SPSS version 16.0. P ≤ 0.05 was considered as significant. Results: Majority of the patients i.e. 46 (57.5%) out of 80 were in the age group of 18-30 years with male preponderance. All HIV positive patients with SD had scaly, greasy, itchy, hypo-pigmented and erythematous lesions, & neck (23) and groin (20) were commonest sites. In 39 HIV positive and 22 HIV negative patients, >2 sites were involved. Majority of the HIV negative patients with SD had scaly (40), itchy (24) and hypo-pigmented lesions (27) & dandruff, and scalp (24) & neck (18) were commonest sites. (P<0.05). Twenty HIV positive patients had CD4 count ranging from 200-350 cells/mm3. Malassezia was detected in 38 and 34 HIV positive & negative patients respectively in laboratory diagnosis. Conclusion: Seborrheic Dermatitis has severe presentation at multiple sites in HIV positive patients as compared to HIV negative patients. Key words: Malassezia, Seborrheic dermatitis, HIV positive, HIV negative.

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An unprecedent prevalence of palmoplantar warts among nursing students

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20205593 ◽

2020 ◽

Vol 7 (1) ◽

pp. 44

Author(s):

M. Vijaya Bharathi ◽

Neetha L. ◽

S. Murugan ◽

S. Rajagopal ◽

J. Nivin Simon

Keyword(s):

Nursing Students ◽

Skin Diseases ◽

Seborrheic Dermatitis ◽

First Year ◽

Medical Sciences ◽

First Year Students ◽

Common Skin ◽

Skin Conditions ◽

Nursing College ◽

Hands And Feet

Background: Skin diseases are common contributors to disease morbidity worldwide, particularly among adolescents. Although skin diseases are rarely lethal, they can have a significant impact in terms of treatment cost, absence from school, and psychological distress. Verruca vulgaris (cutaneous warts) is a common skin problem in adolescents that commonly affects the hands and feet. The aim of the study was to determine the prevalence of warts among nursing students.Methods: Three hundred and twenty eight undergraduate degree students of nursing college were examined for skin conditions after an unprecedented sporadic visitors form the nursing college with palmo-plantar warts. The study was conducted at Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari district during the period of 20 March 2019 to 25 March 2019.Results: Among the 328 students, 102 students (31%) remained healthy dermatologically. Seborrheic dermatitis was found among 145 students (4.4%), pediculosis was found in 40 students (12%). 34 students were having palmoplantar warts (10.4%). Among these, nearly 30 were having palmar warts and only 4 were having plantar and palmar warts. 83 first year students were not having any warts in their hands or foot, whereas 11 among 2nd year, 16 among 3rd year students and 7 among 4th year students were having viral warts. Prevalence was more among 2nd and 3rd year students.Conclusions: Screening of hostel students should also include for the presence of viral skin disease like herpes simplex, Herpes zoster and HPV infections and they should be treated then and there to break the chain of transmission.

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Secondary Syphilis in Patients Treated at the City Institute for Skin and Venereal Diseases in Belgrade from 2010 to 2014

Serbian Journal of Dermatology and Venerology ◽

10.1515/sjdv-2015-0005 ◽

2015 ◽

Vol 7 (2) ◽

pp. 53-60

Author(s):

Milan Bjekić

Keyword(s):

Skin Diseases ◽

Clinical Manifestations ◽

Secondary Syphilis ◽

Hiv Positive ◽

Venereal Diseases ◽

Cutaneous Manifestations ◽

Source Of Infection ◽

Sex With Men ◽

The City ◽

Hiv Negative

AbstractThe aim of this study was to analyze the characteristics and clinical manifestations of secondary syphilis among patients registered at the City Institute for Skin and Venereal Diseases in Belgrade, during the period from 2010 to 2014. The study was designed as a case-note review. In the five-year period, a total of 62 patients with secondary syphilis were registered. The average patient age was 32 years. There were 45 (72.6%) HIV-negative, and 17 (27.4%) HIV-positive patients. The incidence of HIV–positive patients was significantly different from random distribution (p = 0.016). All HIV-positive patients were unmarried men. A significant percentage of HIV-positive patients were unemployed (p < 0.001), reported unknown source of infection (p = 0.002) and were all homosexuall (p = 0.026). More than 25% of all patients with syphilis had a history of chancres, and it was still present at the time of examination in 11.3% of all patients. The majority of cases (87.1%) had a rash, and lymphadenopathy was found in 20% of patients. However, syphilitic alopecia was detected only in HIV-positive cases (p = 0.004). There were no statistically significant differences between HIV-positive and HIV-negative patients in regard to other clinical manifestations, such as mucous patches and condylomata lata. Being a great imitator, secondary syphilis may manifest in a myriad of diverse morphological entities and clinical manifestations. We review a range of cutaneous manifestations of secondary syphilis and skin diseases it may mimic. Clinicians must be vigilant and consider syphilis in differential diagnosis, and maintain a high index of suspicion, especially when assessing vulnerable populations, such as men who have sex with men and HIV-infected individuals.

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Prevalence of skin disease among adolescent girls and their impact on quality of life

Pediatric Review International Journal of Pediatric Research ◽

10.17511/ijpr.2021.i02.08 ◽

2021 ◽

Vol 8 (2) ◽

pp. 116-120

Author(s):

Dr. Deepika Gurram ◽

Keyword(s):

Quality Of Life ◽

Skin Disease ◽

Social Engagement ◽

Skin Diseases ◽

Seborrheic Dermatitis ◽

Age Groups ◽

Life Quality ◽

Self Confidence ◽

Common Skin

Introduction: Skin diseases can adversely affect the quality of life of an individual. Adolescence is acritical time in biophysical development and adverse skin conditions during this period can alter thegrowth in self-confidence and self-esteem and social engagement. Purpose: The present study wasdesigned to assess the burden, the pattern of skin diseases and their impact on their quality of life inadolescent students. Materials and Methods: A total of 23 schools having 3581 students between10-16 years of age were visited, out of which 3367 students were covered and screened. Skincharacteristics such as the severity of skin disease were recorded by the attended physician. Adermatology life quality index (DLQI) questionnaire was used to assess the effect of skin diseases ontheir quality of life. Results: Among the total cases 2,783 (82%) had skin diseases, of the651(19%) had two or more 2 skin diseases. Prevalence of infectious skin diseases was more in (10-12) young age groups 78.5% as compared to (13-16) later age groups of 55.2% (p<0.01).Pediculosis (52%) has a high point of prevalence, followed by scabies (25%), Pityriasis alba (6.6%),Seborrheic dermatitis (5%), Pyoderma (3.3%), Acne (2.6%) and Tinea (2%). Pediculosis andscabies together constitute 77% of all skin diseases. Conclusion: Good hygiene practices likeregular bathing, regular head wash, and hand wash should be taught to children. Hence training ofschool teachers and PHC doctors regarding the management of common skin diseases and Healtheducation to parents or guardians of children about Hygienic measures, sexual behaviour and needof seeking medical advice.

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Efficacy and Safety of Oral Ivermectin and Topical Permethrin in the Treatment of Scabies

TAJ Journal of Teachers Association ◽

10.3329/taj.v33i1.49824 ◽

2020 ◽

Vol 33 (1) ◽

pp. 41-47

Author(s):

Mohsena Akhter ◽

Ishrat Bhuiyan ◽

Zulfiqer Hossain Khan ◽

Mahfuza Akhter ◽

Gulam Kazem Ali Ahmad ◽

...

Keyword(s):

Skin Diseases ◽

Close Contact ◽

Randomized Study ◽

Sarcoptes Scabiei ◽

Efficacy And Safety ◽

Common Skin ◽

Group A ◽

The Mean ◽

The Difference ◽

Group B

Background: Scabies is one of the most common skin diseases in our country. It is caused by the mite Sarcoptes scabiei var hominis, which is an ecto-parasite infesting the epidermis. Scabies is highly contagious. Prevalence is high in congested or densely populated areas. Individuals with close contact with an affected person should be treated with scabicidal which is available in both oral and topical formulations. The only oral but highly effective scabicidal known to date is Ivermectin. Amongst topical preparations, Permethrin 5 % cream is the treatment of choice. Objective: To evaluate the efficacy & safety of oral Ivermectin compared to topical Permethrin in the treatment of scabies. Methodology: This prospective, non-randomized study was conducted at the out-patient department of Dermatology and Venereology of Shaheed Suhrawardy Medical College & Hospital over a period of 6 months, from August 2016 to January 2017. The study population consisted of one hundred patients having scabies, enrolled according to inclusion criteria. They were divided into two groups. group A was subjected to oral Ivermectin and the group B to Permethrin 5% cream. Patients were followed up on day 7 and 14 for assessment of efficacy and safety. Result: The mean scoring with SD in group A (Ivermectin) and group B (Permethrin) were 8.26 ± 2.22 and 7.59 ± 2.01 respectively at the time of observation. The difference between the mean score of the two group is not significant (p=0.117) the mean scoring with SD in group A and group B were 4.54 ± 2.05 and 1.64 ± 1.84 respectively at 7thdays. The difference between the mean score of the two group is significant (p<0.001). The mean scoring with SD in group A and group B were 2.68± 2.35 and .36± 1.10 respectively at 14th day difference between the mean score of the group is significant (p<0.001). Conclusion: Topical application of permethrin 5% cream is more effective and safer than oral Ivermectin in the treatment of scabies. TAJ 2020; 33(1): 41-47

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Incidence of Cytological Abnormalities in Pap's Smear in HIV Positive Women

Journal of Medical Research and Innovation ◽

10.15419/jmri.136 ◽

2018 ◽

Vol 2 (S1) ◽

pp. e000136

Author(s):

Suhana Jotva ◽

Hemani Desai ◽

Hansa Goswami

Keyword(s):

Trichomonas Vaginalis ◽

Clinical History ◽

Hiv Positive ◽

Squamous Intraepithelial Lesions ◽

Squamous Cells ◽

Medical College ◽

Hiv Positive Women ◽

Cytological Abnormalities ◽

Intraepithelial Lesions ◽

Hiv Negative

Aims and Objectives: The aim of present study is to estimate the frequency of abnormal PAP’s smears and mainly to detect precancerous and cancerous lesions as well as inflammatory lesions in HIV infected women. Methodology: Our study was a retrospective study of total 130 cases and PAP’s smears were examined in cytology section in Department of Pathology, BJ Medical College, Ahmedabad from 1st March 2017 to 31st August 2017. Both HIV positive and HIV negative patients were included in the study. 80 patients were HIV negative and 50 patients were HIV positive. The clinical history and relevant parameters were noted. All the smears were processed by a conventional method using Papanicolaou stain. Results: Out of 130 cases, 118 cases were reported negative for intraepithelial lesions or malignancy (NILM). Five cases were positive for squamous intraepithelial lesions (SIL) out of which four were HIV positive. Seven cases were of atypical squamous cells of undetermined significance (ASCUS) out of which 5 were HIV positive. Three cases were showing bacterial vaginosis. 1 case was showing Trichomonas Vaginalis. 19 cases were showing changes of non-specific inflammation. 6 cases were showing atrophic changes. Conclusion: HIV infected women are at more risk to develop cervical cytological abnormalities. The study revealed a maximum number of non-specific inflammatory smears followed by smears showing atrophic changes. Smears suspicious for malignancy (ASCUS) and smears showing squamous intraepithelial lesions (SIL) were more common in HIV positive patients. Thus regular PAP’s smears screening as recommended by National AIDS Control Organization (NACO) will help in early detection of cervical abnormalities in HIV positive women.

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