scholarly journals The Difficulties of Diagnosing Tumor of the Ewing’s Family of Sarcomas in an Emergency Hospital (Clinical Observation)

2021 ◽  
pp. 55-66
Author(s):  
A. Yu. Vasil’ev ◽  
T. V. Pavlova ◽  
V. A. Nechaev ◽  
Z. N. Baratashvili ◽  
O. O. Manuylova
Keyword(s):  
Young Patient ◽  
Clinical Case ◽  
Clinical Observation ◽  
Rare Tumor ◽  
Clinical Pattern ◽  
Emergency Hospital

The author presents his own clinical case demonstrating the long stage and difficulties in diagnosing a rare tumor of the Ewing’s Family of Sarcomas in a young patient, due to the peculiarity of the course of the disease, manifested by a non-pathognomonic clinical pattern.

Clinical case of periostitis in pregnant women complicated by sepsis

2020 ◽  
pp. 61-63
Author(s):  
S. Sh. Kakvaeva ◽  
M. A. Magomedova ◽  
A. N. Dzhalilova
Keyword(s):  
Pregnant Woman ◽  
Multiple Organ Failure ◽  
Pregnant Women ◽  
Organ Failure ◽  
Clinical Case ◽  
Clinical Observation ◽  
Infectious Agent ◽  
Modern Medicine ◽  
Multiple Organ ◽  
Number Of Patients

One of the most serious problems of modern medicine is sepsis. The number of patients undergoing this complication is 20–30 million (WHO) annually and has no tendency to decrease. Sepsis is characterized by severe multiple organ failure due to a violation of the response of the macroorganism to an infectious agent. Moreover, it is dangerous with high mortality. Sepsis often develops in patients with immunodeficiency conditions, which primarily include pregnant women. The article presents a clinical observation of a case of periostitis in a pregnant woman complicated by a septic state.

Detergent properties as the basis of the dimexide therapeutic effect in AA-amyloidosis infectious nature (clinical case analysis)

2020 ◽  
Vol 24 (2) ◽  
pp. 60-71
Author(s):  
V. Rameev ◽  
L. Kozlovskaya ◽  
A. Rameeva ◽  
P. Tao
Keyword(s):  
Therapeutic Effect ◽  
Medical Practice ◽  
Clinical Case ◽  
Clinical Observation ◽  
Case Analysis ◽  
Systemic Amyloidosis ◽  
Aa Amyloidosis ◽  
Functional Amyloid ◽  
History Of

The article discusses the current possibilities of postinfectious AA-amyloidosis treatment with dimexide on the example of clinical observation, discribes in detail the problem of functional amyloid and debates the prospects of the principle of amyloid resorption in the treatment of systemic amyloidosis. The history of the use of dimexide in medical practice is given, thenecessary dataon the pharmacology of dimexide are presented.

COVID-19-associated orthostatic hypotension syndrome: direct and indirect mechanisms of development

2021 ◽  
Vol LIII (3) ◽  
pp. 64-70
Author(s):  
Elena G. Mendelevich ◽  
Alsu A. Saifeeva ◽  
Artur I. Kurbanov
Keyword(s):  
Nervous System ◽  
Orthostatic Hypotension ◽  
Clinical Case ◽  
Clinical Observation ◽  
Thrombus Formation ◽  
Correct Diagnosis ◽  
Aim Analysis ◽  
Angiotensin Converting Enzyme 2 ◽  
Mechanisms Of Development ◽  
Near Future

Background. The article presents an observation of the clinical case of orthostatic hypotension that developed after an infection caused by the SARS-CoV-2 virus. The issues of etiology, pathogenesis, diagnosis are outlined. The complexity of diagnosis at the stage of clinical observation is due to the comorbidity of possible mechanisms and the difficulty of determining the primary factor. Taking into account the study of variants of direct and indirect action of this 2019-nCoV, the description of the clinical observation of orthostatic hypotension supplements the data on the spectrum of manifestations of this disease. Aim. Analysis of the clinical case of the development of orthostatic hypotension in the post-acute period of COVID-19. Material. When conducting a literature review on the selected topic, various sources were considered. The search depth was over 7 years. For the recruitment of literature, Internet platforms UpToDate, PubMed, Medscape were used. Russian and foreign sources were studied. Methods. Anamnesis collection, objective research, specialized tests, laboratory and instrumental research methods, study of disease history, literature sources on orthostatic hypotension and the effect of COVID-19 on the autonomic nervous system. Results. The analysis of this case with the determination of the leading mechanism of orthostatic hypotension is extremely difficult. Probably, there is a combination of factors: direct and indirect effects on the nervous system at COVID-19. The direct effect is associated with the interaction of the virus with the angiotensin converting enzyme 2 receptors in the nervous system, which causes a significant increase in the concentration of bradykinin and the development of hypotension. An indirect effect is due to both increased thrombus formation with the development of PE, and autonomic dysfunction, within the framework of secondary polyneuropathy of fine fibers. Conclusion. It is likely that in the near future the number of such patients in the practice of doctors will increase, therefore, timely and correct diagnosis of these conditions, with their careful management, will be the fundamental postulates in the recovery of patients. Drawing attention to this topic will possibly expand our understanding of the spectrum of complications of COVID-19 and will greatly complement the information available today.

Cholangiocarcinoma in pregnancy (clinical case)

2020 ◽  
pp. 19-27
Author(s):  
A. Yu. Ralnikova ◽  
V. F. Bezhenar ◽  
B. V. Arakelyan ◽  
N. A. Tatarova ◽  
M. E. Malysheva
Keyword(s):  
Pregnant Woman ◽  
Clinical Case ◽  
Clinical Observation ◽  
Late Diagnosis ◽  
Biliary Cancer ◽  
In Pregnancy

The article discusses the problems of diagnosing biliary cancer during pregnancy, proceeding under the guise of complications associated with gestation. A clinical observation of late diagnosis of cholangiocarcinoma in a pregnant woman is presented.

Clinical case: diagnosis of gastric cancer in a young patient

Therapy ◽  
2021 ◽  
Vol 5_2021 ◽  
pp. 136-140
Author(s):  
Druk I.V. Druk ◽  
Pavlov A.V. Pavlov ◽  
Kosenok V.K. Kosenok ◽  
Fadeeva E.A. Fadeeva ◽  
Pavlov A.A. Pavlov ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Young Patient ◽  
Clinical Case ◽  
Case Diagnosis

scholarly journals To the Question of the Role of Radiation Methods in the Diagnosis of Locoregional Recurrence of Colon Cancer (Clinical Case)

2017 ◽  
pp. 120-125 ◽  
Author(s):  
N. V. Nudnov ◽  
U. Stanoevich ◽  
E. N. Grebenkin ◽  
E. V. Sidorova
Keyword(s):  
Colon Cancer ◽  
Locoregional Recurrence ◽  
Clinical Case ◽  
Clinical Observation ◽  
Lymphatic System ◽  
Tumor Bed ◽  
Oncological Diseases ◽  
Cecum Cancer

Coloncancer is one of the first places in the structure of oncological diseases. According to statistics, edited by A.D. Kaprin, V.V. Starinskii, G.V. Petrova ofRussiafor 2015 was initially 36494 case of colorectal cancer, while 2% of cases are not diagnosed. Recurrence of colon cancer can occur at any stage regardless of the time elapsed after the radical treatment. Locoregionally originally is the presence of a tumor in the area of primary operation, which is represented by the primary tumor bed, the anastomosis, mesentery of the colon with lymphatic system, peritoneum and adjacent organs. Often after a diagnosis of “recurrence of the tumor in the colon” to the patient it is possible to provide only palliative care (colostomy, chemotherapy). The article cited clinical observation, confirming the important role of radiation techniques in determination of tactics of treatment of locoregional recurrence of the cecum cancer. 

scholarly journals Polyarthritis associated with COVID-19 (clinical case)

2021 ◽  
Vol 15 (5) ◽  
pp. 76-79
Author(s):  
E. S. Aronova ◽  
B. S. Belov
Keyword(s):  
Clinical Data ◽  
Laboratory Tests ◽  
Clinical Case ◽  
Clinical Observation ◽  
Laboratory Data ◽  
Careful Study ◽  
Instrumental Methods

The article describes the clinical observation of the onset of polyarthritis after COVID-19. Clinical data, laboratory tests' and instrumental methods results in dynamics, as well as approaches to therapy are presented. The discussion reflects modern views on the causes of the development of articular syndrome after SARS-CoV-2, with special attention to the need for a careful study of the history, clinical and laboratory data of patients with COVID-19.

scholarly journals Combination of ulcerative colitis with cirrhosis of the liver in the outcome of primary sclerosing cholangitis

2020 ◽  
Vol 174 (5) ◽  
pp. 104-107
Author(s):  
A. V. Nikitin ◽  
A. I. Khavkin ◽  
T. A. Skvortsova ◽  
G. V. Volynets ◽  
A. O. Atameeva
Keyword(s):  
Ulcerative Colitis ◽  
Weight Loss ◽  
Primary Sclerosing Cholangitis ◽  
Liver Damage ◽  
Sclerosing Cholangitis ◽  
Clinical Case ◽  
Clinical Observation ◽  
Lower Extremities ◽  
Cirrhosis Of The Liver ◽  
Extraintestinal Manifestation

A clinical case of a combination of ulcerative colitis with cirrhosis in the outcome of primary sclerosing cholangitis in a twelve-year-old child is presented. The uniqueness of the clinical observation lies in the atypical onset of ulcerative colitis in the form of complaints of weakness and headache, as well as detected anemia of 3 severity. It is important that the child lacked diarrhea, blood in the stool, tenesmus, weight loss, and fever. Of the most characteristic signs of liver damage, only itching of the skin of the lower extremities was noted. As a result, the child was diagnosed with cirrhosis of the liver at the end of the extraintestinal manifestation of ulcerative colitis — primary sclerosing cholangitis.

scholarly journals Progressing radiation injury of the rectum. Clinical observation

2020 ◽  
Vol 23 (3) ◽  
pp. 31-36
Author(s):  
T. E. Skvortsova ◽  
I. А. Oganezova
Keyword(s):  
Radiation Therapy ◽  
Clinical Case ◽  
Radiation Injury ◽  
Clinical Observation ◽  
Clinical Manifestations ◽  
Radiation Injuries ◽  
Common Complication ◽  
Pelvic Organs ◽  
Chronic Radiation ◽  
Progressive Course

Radiation damage to the rectum is the most common complication in radiation therapy of malignancies of pelvic organs. Clinical manifestations of chronic radiation proctitis can occur both 3 months after completion of therapy and decades later. Late radiation injuries to the intestine often has a persistent course, drug treatment is prolonged and repeated, in severe cases surgical treatment is required. The article presents literature data on pathophysiology, clinical picture, diagnostics and possibilities of treating this pathology. A clinical case reflecting the progressive course of the disease is described.

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