Antibiotics induced lactase deficiency as cause for abdominal involuntary movements

A rare condition is temporary but recurrent onset of involuntary motion sequences in the abdominal region. They demands for an extensive diagnostic workup. Therapeutic options are limited. The successful treatment of this spinal myoclonus or abdominal involuntary movements resembling syndrome prompted this report.

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Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin

Journal of Medical Microbiology ◽

10.1099/jmm.0.023010-0 ◽

2010 ◽

Vol 59 (11) ◽

pp. 1383-1386 ◽

Cited By ~ 34

Author(s):

Romney M. Humphries ◽

Theodoros Kelesidis ◽

Jennifer Dien Bard ◽

Kevin W. Ward ◽

Debika Bhattacharya ◽

...

Keyword(s):

Antimicrobial Resistance ◽

Klebsiella Pneumoniae ◽

Successful Treatment ◽

Poor Prognosis ◽

Therapeutic Options ◽

Resistant Isolate ◽

High Dose

The spread of antimicrobial resistance among members of the Enterobacteriaceae is a significant clinical threat. We report the treatment of pan-resistant Klebsiella pneumoniae bacteraemia with combination tigecycline and colistin in a 49-year-old male and review available therapeutic options. Despite a poor prognosis, the patient recovered, but remains colonized with the pan-resistant isolate.

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Treatment of Locking of the Metacarpophalangeal Joint of the Thumb

Journal of Hand and Microsurgery ◽

10.1055/s-0039-3400441 ◽

2019 ◽

Vol 12 (01) ◽

pp. 62-66

Author(s):

Yoshifumi Harada ◽

Atsuyuki Inui ◽

Yutaka Mifune ◽

Hanako Nishimoto ◽

Takeshi Kokubu ◽

...

Keyword(s):

Surgical Treatment ◽

Successful Treatment ◽

Open Reduction ◽

Case Series ◽

Rare Condition ◽

Metacarpophalangeal Joint ◽

The Other ◽

Chronic Case ◽

Metacarpal Head ◽

Thumb Metacarpophalangeal Joint

AbstractLocking of the thumb metacarpophalangeal joint is a relatively rare condition. We report successful treatment in 11 cases of locking of the thumb. Ten patients were diagnosed at an average of 3.2 days (range: 0–21 days) from the injury onset, whereas one patient was diagnosed at 4 months from the injury. Seven of 11 cases underwent successful manual reduction, whereas the other four cases required surgical treatment. Among the surgically treated cases, all cases had a sharp prominent of the radial condyle of the metacarpal head. Therefore, this case series showed 1 chronic case and 4 of 10 cases with a nonround shape of metacarpal heads requiring open reduction.

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Spinal myoclonus: report of four cases

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x1993000400012 ◽

1993 ◽

Vol 51 (4) ◽

pp. 498-501 ◽

Cited By ~ 3

Author(s):

James Pitágoras de Mattos ◽

Ana Lúcia Z. Rosso ◽

Antonio J. V. Carneiro ◽

Sergio Novis

Keyword(s):

Spinal Cord ◽

Spastic Paraplegia ◽

Devic’S Disease ◽

Involuntary Movements ◽

Fourth Patient ◽

Devic's Disease ◽

Spinal Myoclonus ◽

The Mean ◽

The Right ◽

Mean Time

Four cases of spinal myoclonus are described, three males and one female. The mean age was 51 years (28-75 years). The mean time between the onset of the myelopathy and the myoclonic jerks was 4.3 months (1-8 months). The involuntary movements were determined by trauma, Devic's disease, tuberculous myelopathy and tumor. Three patients had spastic paraplegia with bilateral myoclonus more evident on the right side. The fourth patient had a flaccid paraplegia with symmetrical jerks. The data suggest that different processes (trauma, demyelinating, infection and tumor) affecting the spinal cord may cause the same type of involuntary movements.

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Novel Blood Biomarkers for a Diagnostic Workup of Acute Aortic Dissection

Diagnostics ◽

10.3390/diagnostics11040615 ◽

2021 ◽

Vol 11 (4) ◽

pp. 615

Author(s):

Anja Forrer ◽

Felix Schoenrath ◽

Michael Torzewski ◽

Jens Schmid ◽

Urlich F. W. Franke ◽

...

Keyword(s):

Chest Pain ◽

Aortic Dissection ◽

Acute Aortic Dissection ◽

Troponin T ◽

Acute Chest Pain ◽

Rare Condition ◽

Interleukin 10 ◽

Diagnostic Workup ◽

Aortic Tissue ◽

Plasminogen Activator Inhibitor 1

Acute aortic dissection (AAD) is a rare condition, but together with acute myocardial infarction (AMI) and pulmonary embolism (PE) it belongs to the most relevant and life-threatening causes of acute chest pain. Until now, there has been no specific blood test in the diagnostic workup of AAD. To identify clinically relevant biomarkers for AAD, we applied Proseek® Multiplex assays to plasma samples from patients with AAD, AMI, PE, thoracic aortic aneurysm (TAA), and non-cardiovascular chest pain (nonCVD). Subsequently, we validated top hits using conventional immunoassays and examined their expression in the aortic tissue. Interleukin 10 (IL-10) alone showed the best performance with a sensitivity of 55% and a specificity of 98% for AAD diagnosis. The combination of D-dimers, high-sensitive troponin T (hs-TnT), interleukin 6 (IL-6), and plasminogen activator inhibitor 1 (PAI1) correctly classified 75% of AAD cases, delivering a sensitivity of 83% and specificity of 95% for its diagnosis. Moreover, this model provided the correct classification of 77% of all analyzed cases. Our data suggest that IL-10 shows potential to be a rule-in biomarker for AAD. Moreover, the addition of PAI1 and IL-6 to hs-TnT and D-dimers may improve the discrimination of suspected AAD, AMI, and PE in patients presenting with acute chest pain.

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Successful treatment of highly recurrent facial baroparesis in a frequent high-altitude traveler: a case report

Journal of Medical Case Reports ◽

10.1186/s13256-020-02557-9 ◽

2020 ◽

Vol 14 (1) ◽

Author(s):

Jason P. Caffrey ◽

Jason W. Adams ◽

Isabel Costantino ◽

Kristin Klepper ◽

Elina Kari ◽

...

Keyword(s):

High Altitude ◽

Successful Treatment ◽

Rare Condition ◽

Pressure Equalization ◽

Seventh Cranial Nerve ◽

Commercial Airline ◽

Bone Segment ◽

Patient Reported ◽

History Of ◽

The Right

Abstract Background Facial baroparesis is a palsy of the seventh cranial nerve resulting from increased pressure compressing the nerve along its course through the middle ear cavity. It is a rare condition, most commonly reported in barotraumatic environments, in particular scuba diving and high-altitude air travel. We report here an unusual case of highly frequent baroparesis, workup, and successful treatment. Case presentation A 57-year-old Caucasian male frequent commercial airline traveler presented with a 4-year history of recurrent episodes of right-sided facial paralysis and otalgia, increasing in both frequency and severity. Incidents occurred almost exclusively during rapid altitude changes in aircraft, mostly ascent, but also during rapid altitude change in an automobile. Self-treatment included nasal and oral decongestants, nasal corticosteroids, and warm packs. Temporal bone computed tomography (CT) scan revealed possible right-sided dehiscence of the tympanic bone segment; audiogram and magnetic resonance imaging of the internal auditory canals were unremarkable. After a diagnosis of facial nerve baroparesis was made, the patient underwent myringotomy with insertion of a pressure equalization tube (PET) into the right tympanic membrane. Despite re-exposure to altitude change multiple times weekly post-treatment, the patient reported being symptom-free for more than 6 months following intervention. Conclusions Prompt PET insertion may represent the preferred treatment for individuals who suffer recurrent episodes of facial baroparesis. Education regarding this rare condition may prevent unnecessary testing and treatment of affected patients. Future studies should explore the pathophysiology and risk factors, compare therapeutic options, and provide follow-up data to optimize the management of affected patients.

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Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab

Case Reports in Neurological Medicine ◽

10.1155/2021/5591559 ◽

2021 ◽

Vol 2021 ◽

pp. 1-6

Author(s):

Mick B. Reedy ◽

Yanping Wang ◽

Brad R. Beinlich ◽

William Nicholas Rose

Keyword(s):

Cognitive Impairment ◽

Case Report ◽

Corpus Callosum ◽

Successful Treatment ◽

Treatment Guidelines ◽

Rare Condition ◽

Evoked Responses ◽

Auditory Evoked Responses ◽

Susac Syndrome ◽

Established Treatment

We present a case report of a patient with incomplete Susac syndrome. He had cognitive impairment, corpus callosum lesions, and vestibulocochlear dysfunction on brainstem auditory evoked responses. He was treated with methylprednisolone and plasmapheresis, improved, and then, also received rituximab. His improvement has been lasting as of this writing. This case shares our experience with a successful treatment of this rare condition that is incompletely understood and lacks well-established treatment guidelines.

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Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options

Journal of Hematology & Oncology ◽

10.1186/1756-8722-4-10 ◽

2011 ◽

Vol 4 (1) ◽

Cited By ~ 75

Author(s):

Gerhard J Molderings ◽

Stefan Brettner ◽

Jürgen Homann ◽

Lawrence B Afrin

Keyword(s):

Mast Cell ◽

Cell Activation ◽

Diagnostic Workup ◽

Therapeutic Options ◽

Mast Cell Activation ◽

Practical Guide ◽

Mast Cell Activation Disease

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Abdominal Wall Dyskinesia: Case Report

Case Reports in Neurology ◽

10.1159/000504336 ◽

2020 ◽

Vol 12 (1) ◽

pp. 69-72 ◽

Cited By ~ 1

Author(s):

Leyla Cavdar ◽

Solomon Ajasin ◽

Scott Woolf ◽

Robert Fekete

Keyword(s):

Case Report ◽

Abdominal Surgery ◽

Abdominal Wall ◽

Dopamine Receptor ◽

Clinical Presentation ◽

Anterior Abdominal Wall ◽

Rare Condition ◽

Receptor Blocking ◽

Involuntary Movements ◽

Tardive Syndrome

The clinical presentation of repetitive choreiform involuntary movements of the anterior abdominal wall was first introduced as “belly dancer’s dyskinesia.” Etiologies of this rare condition include idiopathic causes, medication inducement, or post-abdominal surgery. We report a case of orobuccal stereotypic movements and abdominal wall dyskinesia secondary to prochlorperazine intake. The movements began 2 weeks after cessation of prochlorperazine. The patient took this dopamine receptor-blocking medication for 6 months to treat nausea due to chemotherapy. To our knowledge, abdominal wall dyskinesia as a tardive syndrome of prochlorperazine has not been previously reported.

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Involuntary movements and AIDS: report op seven cases and review of the literature

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x1993000400011 ◽

1993 ◽

Vol 51 (4) ◽

pp. 491-497 ◽

Cited By ~ 15

Author(s):

James Pitágoras de Mattos ◽

Ana Lúcia Z. Rosso ◽

Rosalie Branco Corrêa ◽

Sérgio Novis

Keyword(s):

Opportunistic Infection ◽

Drug Users ◽

Review Of The Literature ◽

Involuntary Movements ◽

Aids Virus ◽

Rubral Tremor ◽

Spinal Myoclonus ◽

Male Patients ◽

The Mean ◽

Aids Diagnosis

We studied 1086 AIDS patients in the last six years. Of these 389 (35.82%) had neurological manifestation and 7 (1.8%) male patients had abnormal involuntary movements (parkinsonism in 3, hemichorea-hemiballism in 2, spinal myoclonus in 1 and rubral tremor in another). All patients were men, 5 white and 2 black. Four were homosexual, 2 drug-users and 1 bisexual. The mean age was 33.14 years. The time between AIDS diagnosis and the onset of movement disorders was 23.8 months in 5 patients and in 2 it was the first symptom. The parkinsonian patients did not show any opportunistic infection in conection with the neurological symptoms but in the remaining four cases this relationship was suggested. The data showed that not only the opportunistic infection but also the AIDS virus may play an important role on the development of involuntary movements.

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