Chlorophyll extraction from Egyptian Luffa leaf

This study examined factors affecting on chlorophyll extraction from Egyptian Luffa leaf for using as food colorant. Optimal conditions for chlorophyll extraction were ethanol 96% for 97 minutes at 49oC and extraction speed at 123 rpm. The quality of extracts was investigated for microorganisms, heavy metals and antioxidant activity by using the DPPH (2-2-diphenyl-1- DPPH) method. The free radical scavenging activities of extract presented by the IC50 value was 261,7 μg/mL.

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ANTIOXIDANT ACTIVITIES OF ROPINIROLE AND PRAMIPEXOLE NOVEL DRUGS USED IN TREATMENT OF PARKINSONISM: AN IN VITRO APPROACH

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2016.v9s3.14861 ◽

2016 ◽

Vol 9 (9) ◽

pp. 105 ◽

Cited By ~ 1

Author(s):

Preetha Selva ◽

Srinivasan Vengadassalapathy

Keyword(s):

Free Radical ◽

Dopamine Agonist ◽

Antioxidant Activities ◽

Radical Scavenging ◽

Free Radical Scavenging ◽

Novel Drugs ◽

Dpph Method ◽

Selective Dopamine ◽

Free Radical Scavenging Activities

ABSTRACTObjective: The objective of this study is to evaluate and compare the free radical scavenging activities of selective dopamine agonist namely ropiniroleand pramipexole.Methods: The antioxidant activity of ropinirole and pramipexole at various concentrations was done by 1, 1-diphenyl-2picrylhydrazyl (DPPH) freeradical scavenging assay comparing it with ascorbic acid which was taken as standard.Results: The free radical scavenging property as measured by DPPH method showed that ropinirole and pramipexole have got a potent free radicalscavenging activity with that of ascorbic acid.Conclusion: Novel drugs such as pramipexole and ropinirole are promising molecules in the field of oxidative damage related neurodegenerativedisorders providing us an optimistic targeted approach toward neuroprotection.Keywords: Free radical scavenging, 1, 1-diphenyl-2picrylhydrazyl assay, Anti-Parkinson’s, Dopamine agonist.

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An Indian Folkore Phytomedicine Perilla frutescens L.: Free Radical Scavenging Property along with Metal Detection by ICP-MS

Asian Journal of Chemistry ◽

10.14233/ajchem.2021.23155 ◽

2021 ◽

Vol 33 (4) ◽

pp. 945-948

Author(s):

Ajay Singh ◽

Arunesh Kumar Dixit ◽

S. Farooq ◽

Zafar Mehmood ◽

Suman Lata Chhimwal

Keyword(s):

Antioxidant Activity ◽

Free Radical ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Free Radical Scavenging ◽

Perilla Frutescens ◽

Considerable Proportion ◽

Ic50 Value ◽

Dpph Method

In present study, free radical scavenging activity of methanolic extract of all parts (leaves, seeds, root, stem and flower) of Perilla frutescens L. has been estimated. The promising results, among the five plant parts leaves, seeds, root, stem, flower and the standard tested for the in vitro antioxidant activity using the DPPH method, the crude methanolic extracts of all parts showed antioxidant activity, with IC50 values of 5.95 ± 0.10, 8.28 ± 0.20, 66.27 ± 0.17, 80.03 ± 0.10 and 122.35 ± 0.17 μg/mL, respectively. The IC50 value for ascorbic acid was 5.19 ± 0.26 μg/mL. While butylated hydroxyl toluene (BHT) a synthetic commercial antioxidant has comparatively high IC50 value of 108.46 ± 0.57 μg/mL. Presence of zinc in all parts of plant in the range 17.20 ± 0.22 to 33.56 ± 0.32 ppm further supports the strong antioxidant activity of Perilla frutescens L. The phytochemical tests indicated that all parts of Perilla frutescens L. have considerable proportion of important phytochemicals and are in rich source of secondary metabolites like polyphenols, tannins, alkaloids and flavonoids. Several of such compounds are known to possess potent antioxidant activity.

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