Alterations of Serum Osteocalcin Levels in Patients with Legg-Calvé-Perthes

Background Legg-Calvé-Perthes disease (LCPD) is a paediatric form of osteonecrosis that ultimately heals but will cause femoral head and acetabular deformities. The purpose of this study was to investigate the early serum measurement of osteocalcin in children with femoral head necrosis compared with that of healthy children. Methods 20 patients with LCPD (4 girls and 16 boys) and 20 healthy volunteers (5 girls and 15 boys) were enrolled. All patients did not have additional treatment. Blood samples were obtained from all patients pre-operatively in the morning. All cases had hip radiographs. The serum levels of osteocalcin comparisons between the LCPD patients and the healthy volunteers were performed using Wilcoxon signed-rank test. The Spearman rank correlation was used to assess correlation between LCPD grade and serum osteocalcin levels. Significance was set at p = 0.05. Results The 20 patients with LCPD (72.75 ± 24.92 ng/ml) had significantly higher serum osteocalcin levels compared with the healthy group (16.80 ± 4.04 ng/ml) (p≤0.01). Serum osteocalcin levels of different LCPD grades were significantly different (Spearman's p = 0.540, p = 0.014). Conclusions We observed a significant correlation between serum osteocalcin levels and LCPD. These results may be meaningful in clinical practice and to future studies.

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MORPHOFUNCTIONAL DETERMINANTS OF THE EFFECTIVENESS OF ONE VERSUS ONE SMALL-SIDED GAMES IN SOCCER PLAYERS

Journal of Kinesiology and Exercise Sciences ◽

10.5604/01.3001.0013.5095 ◽

2018 ◽

Vol 28 (82) ◽

pp. 45-52

Author(s):

Janusz Jaworski ◽

Tadeusz Ambroży ◽

Dariusz Tchórzewski ◽

Krzysztof Durlik

Keyword(s):

Motor Skills ◽

Rank Correlation ◽

Correlation Coefficients ◽

Training Group ◽

Rank Test ◽

Football Players ◽

Correlation Matrices ◽

Signed Rank ◽

Signed Rank Test ◽

Functional Profiles

Aim. The aim of this report is to identify variables determining the effectiveness of small football games at subsequent stages of training. Material and Methods. The study material comprised the results of tests conducted among 42 football players who were assigned to 3 categories: youngsters, younger juniors and seniors. The scope of the study included basic somatic features, selected motor skills tests and specific coordination tests of motor skills recommended for football players. Detailed correlation matrices were calculated using Spearman’s signed-rank test between all the analysed variables and the overall game perforance index (OPI). For each training group, morpho-functional profiles were calculated taking variables from previous analyses into account. Variables forming the structure of these models were normalised on the T scale. Results. 11 statistically significant Spearman’s signed-rank correlation coefficients were obtained between game performance indices and the analysed variables. In the 3 training groups of football players, considerable diversity of the internal structure of morpho-functional models was noted. In the group of juniors and seniors, differentiation between features was 1.2 of standard deviation. Conclusions. In terms of fitness, the influence of circulatory-respiratory endurance and speed ability on the indicator of overall performance for the seniors’ game was noted. In turn, taking the neuro-functional side of the players’ motor ability into account, correlations with the effectiveness of the game were mainly found within the ability of balance, kinesthetic differentiation and motor adaptation. Such regularities mainly refer to the youngsters and younger juniors.

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Genotoxicity and cytotoxicity of cone beam computed tomography in children

BMC Oral Health ◽

10.1186/s12903-021-01792-w ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Doua H. Altoukhi ◽

Sumer Alaki ◽

Eman El Ashiry ◽

Osama Nassif ◽

Dania Sabbahi

Keyword(s):

Computed Tomography ◽

Cone Beam Computed Tomography ◽

Buccal Mucosa ◽

Condensed Chromatin ◽

Cone Beam ◽

Rank Test ◽

Healthy Children ◽

Significance Level ◽

Signed Rank ◽

Signed Rank Test

Abstract Background Dental radiographs are essential tools for diagnosis. However, there are significant concerns about the dangerous effect of radiation especially on children. The aim of this study was to evaluate genotoxicity and cytotoxicity in the exfoliated cells of buccal mucosa of children subjected to Cone Beam Computed Tomography (CBCT). Methods The study included 18 healthy children aged (9–12 years) who were exposed to CBCT. All CBCT scans were performed with the i-CAT CBCT. Exfoliated buccal cells were scraped from the left and right cheek immediately before the exposure, after 10 ± 2 days, and after 1 month. Cells were stained using Feulgen/fast green stain and examined under light microscopy. Genotoxicity (Micronuclei) and cytotoxicity (condensed chromatin, karyorrhexis, pyknosis, and karyolysis) were scored. Statistical analysis was performed using the McNemar test, Wilcoxon Signed-Rank test, and Mann-Whitney U test at a significance level of p < 0.05. Results There were statistically significant differences in the mean percentages of micronuclei, condensed chromatin, karyorrhexis, pyknosis, and karyolysis before and 10 ± 2 days after the CBCT scan (p < 0.05). There were no statistically significant differences in the frequency of micronuclei, condensed chromatin, karyorrhexis, or pyknosis before and 1 month after the exposure (p > 0.05) except for karyolysis (p < 0.05). Conclusions CBCT may induce genotoxicity and cytotoxicity in buccal mucosa cells of children. Therefore, CBCT should not be prescribed unless necessary as it cannot be considered a risk-free procedure.

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Follow-up study on serum cholesterol profiles in recovered COVID-19 patients

10.21203/rs.3.rs-118803/v1 ◽

2020 ◽

Author(s):

Wenbin Tan ◽

Guiling Li ◽

Li Du ◽

Xiuqi Wei ◽

Xiaoling Cao ◽

...

Keyword(s):

White Blood Cells ◽

Recovery Process ◽

Serum Levels ◽

Rank Test ◽

Reactive Protein ◽

Follow Up Study ◽

Laboratory Values ◽

Signed Rank ◽

Signed Rank Test

Abstract Background: COVID-19 patients develop hypolipidemia. However, it is unknown whether lipid levels have improved in recovered patients.Objective: In this follow-up study, we evaluated serum lipidemia and other physiopathological laboratory values in recovered patients.Methods: A 3–6 month follow-up study was performed between June 15 and September 3, 2020, to examine serum levels of laboratory values in 107 discharged COVID-19 patients (mild = 59; severe/critical = 48; diagnoses on admission). 61 patients had a revisit chest CT scan. A Wilcoxon signed-rank test was used to analyze changes in laboratory values at admission and follow-up.Results: LDL-c and HDL-c levels were significantly higher at follow-up than at admission in severe/critical cases (p < 0.05). LDL-c levels were significantly higher at follow-up than at admission in mild cases (p < 0.05). With adjustment of the factor of traditional Chinese medicine, LDL-c and HDL-c levels were significantly improved at follow-up than at admission in severe/critical cases (p < 0.05). Coagulation and liver laboratory values were significantly lower at follow-up than at admission for patients (p < 0.05). Increases in HDL-c significantly correlated with increases in numbers of white blood cells (p<0.001) and decreases in levels of C-reactive protein (p < 0.05) during patients’ recovery. Residue lesions were observed in CT images in 69% (42 of 61) of follow-up patients.Conclusions: Improvements of LDL-c, HDL-c and incomplete absorption of lung lesions were observed at 3–6 month follow-up for recovered patients, indicating that a long-term recovery process could be required.

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Follow-up study on serum cholesterol profiles in recovered COVID-19 patients

10.1101/2020.12.08.20245977 ◽

2020 ◽

Author(s):

Guiling Li ◽

Li Du ◽

Xiaoling Cao ◽

Xiuqi Wei ◽

Yao Jiang ◽

...

Keyword(s):

White Blood Cells ◽

Recovery Process ◽

Serum Levels ◽

Rank Test ◽

Reactive Protein ◽

Follow Up Study ◽

Laboratory Values ◽

Signed Rank ◽

Signed Rank Test

AbstractCOVID-19 patients develop hypolipidemia. However, it is unknown whether lipid levels have improved in recovered patients. In this study, a 3–6 month follow-up study was performed to examine serum levels of laboratory values in 107 discharged COVID-19 patients (mild = 59; severe/critical = 48; diagnoses on admission). 61 patients had a revisit chest CT scan. A Wilcoxon signed-rank test was used to analyze changes in laboratory values. LDL-c and HDL-c levels were significantly higher at follow-up than at admission in severe/critical cases (p < 0.05). LDL-c levels were significantly higher at follow-up than at admission in mild cases (p < 0.05). With adjustment of the factor of traditional Chinese medicine, LDL-c and HDL-c levels were significantly improved at follow-up than at admission in severe/critical cases (p < 0.05). Increases in HDL-c significantly correlated with increases in numbers of white blood cells (p<0.001) and decreases in levels of C-reactive protein (p < 0.05) during patients’ recovery. Residue lesions were observed in CT images in 69% (42 of 61) of follow-up patients. We concluded that improvements of LDL-c, HDL-c and incomplete absorption of lung lesions were observed at follow-up for recovered patients, indicating that a long-term recovery process could be required.

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Follow-up study on serum cholesterol profiles and potential sequelae in recovered COVID-19 patients

BMC Infectious Diseases ◽

10.1186/s12879-021-05984-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Guiling Li ◽

Li Du ◽

Xiaoling Cao ◽

Xiuqi Wei ◽

Yao Jiang ◽

...

Keyword(s):

White Blood Cells ◽

Recovery Process ◽

Serum Levels ◽

Rank Test ◽

Follow Up Study ◽

Laboratory Values ◽

Signed Rank ◽

Signed Rank Test

Abstract Background COVID-19 patients develop hypolipidemia. However, it is unknown whether lipid levels have improved and there are potential sequlae in recovered patients. Objective In this follow-up study, we evaluated serum lipidemia and various physiopathological laboratory values in recovered patients. Methods A 3–6 month follow-up study was performed between June 15 and September 3, 2020, to examine serum levels of laboratory values in 107 discharged COVID-19 patients (mild = 59; severe/critical = 48; diagnoses on admission). Sixty-one patients had a revisit chest CT scan. A Wilcoxon signed-rank test was used to analyze changes in laboratory values at admission and follow-up. Results LDL-c and HDL-c levels were significantly higher at follow-up than at admission in severe/critical cases (p < 0.05). LDL-c levels were significantly higher at follow-up than at admission in mild cases (p < 0.05). Coagulation and liver functional values were significantly improved at follow-up than at admission for patients (p < 0.05). Increases in HDL-c significantly correlated with increases in numbers of white blood cells (p < 0.001) during patients’ recovery. With exclusion of the subjects taking traditional Chinese medicines or cholesterol-lowering drugs, LDL-c and HDL-c levels were significantly increased at follow-up than at admission in severe/critical cases (p < 0.05). Residue lesions were observed in CT images in 72% (44 of 61) of follow-up patients. Conclusions Improvements of LDL-c, HDL-c, liver functions, and incomplete resolution of lung lesions were observed at 3–6 month follow-up for recovered patients, indicating that a long-term recovery process could be required and the development of sequelae such as pulmonary fibrosis could be expected in some patients.

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Self-relation of persons with different attitudes to the physical “I” in terms of students of different sexes

Вестник Костромского государственного университета им Н А Некрасова ◽

10.34216/2073-1426-2021-27-2-88-96 ◽

2021 ◽

Vol 27 (2) ◽

pp. 88-96

Author(s):

Vera N. Kleva ◽

Valentina S. Chernyavskaya

Keyword(s):

Rank Correlation ◽

Young Men ◽

Female Students ◽

Rank Test ◽

External Appearance ◽

Psychological Counselling ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient ◽

Signed Rank ◽

Signed Rank Test

The article substantiates the factors of self-attitude of persons with different attitudes to the physical “Iˮ. The study involved 80 people – students of economic and psychological fields of training, 52 girls and 28 boys. The average age is 19.7 years. Existence of differences in the self-attitude of young men and girls to their physical “Iˮ is proved – young men are more positive about their physical “Iˮ, are characterised by a higher level of self-attitude, than girls. It is proved that the indicators of self-attitude and attitude to one's physical self are closely interrelated in female students. The study was conducted using theoretical analysis, as well as methods – the test questionnaire “Self-relationsˮ by Vladimir Stolin and Sergey Panteleyev; the methodology “Self-relation to the image of the physical Selfˮ by Anna Cherkashina; the questionnaire “Evaluative content interpretation of the components of the external appearance by Vera Labunskaya and Yelena Belugina; as well as the method of associative experiment. Statistical methods of data processing – nonparametric measures (Mann-Whitney U test, Wilcoxon signed-rank test, Spearman's rank correlation coefficient) – were used. The results showed that women's attitudes about themselves are based on attitudes about their physical “Self” (face, body, clothing, physical appearance). The results of the study can be used in psychological counselling for people with different attitudes towards the physical “Self”.

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Pilates versus resistance exercise on the serum levels of hs-CRP, in the abdominal circumference and body mass index (BMI) in elderly individuals

Motricidade ◽

10.6063/motricidade.6682 ◽

2016 ◽

Vol 12 (1) ◽

pp. 128 ◽

Cited By ~ 1

Author(s):

Maria Adesilda Silva Pestana ◽

Eduardo Martins Netto ◽

Manuella Castro Silva Pestana ◽

Vitor Silva Pestana ◽

Maria Isabel Schinoni

Keyword(s):

Resistance Exercise ◽

Serum Levels ◽

The Elderly ◽

Abdominal Circumference ◽

Rank Test ◽

Elderly Individuals ◽

Signed Rank ◽

Wilcoxon Signed Rank Test ◽

Signed Rank Test ◽

Hs Crp

Recent studies have shown that the elderly exhibit a subclinical state of inflammation associated with increased adipose tissue and several comorbidities. To compare the effects of mat Pilates based exercises and resistance exercise on the serum levels of reactive C protein of high sensitivity (hs-CRP), in the abdominal circumference (AC) and the body mass index (BMI) in the elderly. It is a randomised clinical trial with a sample of 78 elderly individuals (median age 69 years). The active independent variable investigated was nature of treatment intervention (Pilates mat based exercises vs resistance exercise), and the dependent variables were hs-CRP level, AC and BMI. The statistical analysis used Wilcoxon signed rank and Mann-Whitney tests. The correlation between the continuous variables was assessed using Spearman’s coefficient of correlation. The data were analysed using SPSS software version 17.0, and probability values lower than 5% (p< 0.05) were considered statistically significant. Mat Pilates based exercises exhibited reductions in serum hs-CPR level (Wilcoxon signed rank test; z = -2.466, p = 0.01), BMI (Wilcoxon signed rank test; z = -3.295, p = 0.001) and AC (Wilcoxon signed rank test; z = -3.398, p = 0.01). Mat Pilates based exercises promoted a significant reduction of the serum hs-CRP levels and anthropometric measurements in elderly individuals.

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Abstract TP380: Change in the Medication Behavior During One Year After Stroke in Patients With Initial Mild Ischemic Stroke

Stroke ◽

10.1161/str.47.suppl_1.tp380 ◽

2016 ◽

Vol 47 (suppl_1) ◽

Author(s):

Akie Kobayashi ◽

Takako Ichihara ◽

Ayako Tamura

Keyword(s):

Ischemic Stroke ◽

Drug Cost ◽

Medication Compliance ◽

Rank Correlation ◽

Rank Test ◽

P Values ◽

Spearman’S Rank Correlation ◽

Signed Rank ◽

Signed Rank Test ◽

One Year

Background and Purpose: Patients with stroke often stop medication for the prevention. Medication behavior is mainly composed the medication compliance and understanding of the medication. The purpose of this study was to assess change in the medication behavior during one year after initial stroke, and to identify the correlation between medication compliance and understanding of the medication in patients with mild ischemic stroke. Methods: Thirty-one patients with initial mild ischemic stroke were prospectively recruited. Two types of self-reported questionnaires (Medication compliance questionnaires, Understanding of medication questionnaires) were applied at admission (baseline) and 1 year after stroke respectively. Understanding of medication questionnaires contained 4 factors; “motivation”, “capacity”, “understanding” and “drug cost” for the medication. Change in the medication was analyzed by Wilcoxon signed rank test. The correlation between the medication compliance and understanding of medication were analyzed by Spearman’s rank correlation. The p-values<0.05 were considered statistically significant. Results: Among the patients who agreed to participate in this study, 71% were males and 29% were females, with the average age of 66.0±8.4. Lacunar was the most common type of stroke among those patients. Their scores of medication compliance at 1 year after stroke were significantly increased (p<0.01) compared to those in the baseline. Their scores of understanding of medication“the drug cost burden” were also significantly increased (p<0.05).At baseline, there was significant correlation between medication compliance and understanding of medication“hassle for taking medicine”(ρ=0.464,p<0.01 ),“simple medication ” (ρ=0.528,p<0.01 ).At 1 year after stroke, there was significant correlation between medication compliance and understanding of medication“hassle for taking medicine” (ρ=0.381,p<0.05). Conclusions: These data suggest that the estimation of drug cost and hassle for medication primarily affects the medication compliance. Nurses need to focus on not only the medication compliance but also the motion and cognitive function.

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Do the 15D scores and time trade-off (TTO) values of hospital patients' own health agree?

International Journal of Technology Assessment in Health Care ◽

10.1017/s0266462309990869 ◽

2010 ◽

Vol 26 (1) ◽

pp. 117-123 ◽

Cited By ~ 5

Author(s):

Tarja Honkalampi ◽

Harri Sintonen

Keyword(s):

Empirical Relationship ◽

Rank Correlation ◽

Rank Test ◽

Spearman Rank Correlation ◽

Health States ◽

Additional Information ◽

Signed Rank ◽

Hospital Patients ◽

Signed Rank Test ◽

Patient Groups

Objectives: The aim of this study was to estimate an empirical relationship and degree of agreement between the TTO values of patients’ own health and their 15D scores.Methods: A total of 863 hospital patients aged 18–93 years filled in the 15D questionnaire to establish their 15D score and valued their present health with TTO. Wilcoxon signed rank test, the Spearman rank correlation coefficient and Tobit models were used to analyze the relation between the 15D and TTO scores.Results: The null hypothesis of no tendency for one set of scores to be higher or lower than the other set could not be rejected. Apart from dummies for few patients groups, no additional information to the 15D score was found that would have explained significantly the variance in the TTO valuations of patients’ own health. The agreement between these to sets of scores turned out quite good at the aggregate level.Conclusions: To the extent that mean TTO valuations of patients own health are valid for QALY calculations as they at least theoretically should be, and if experience of health states to be valued counts, the 15D scores are also valid without any transformation in a large group of heterogeneous patients. However, in certain patient groups, the agreement was not as good as overall.

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PENGARUH TIRAH BARING TERHADAP PENURUNAN RASA MUAL PADA KLIEN GASTRITIS DI PELAYANAN KESEHATAN

Healthy-Mu Journal ◽

10.35747/hmj.v3i1.386 ◽

2019 ◽

Vol 3 (1) ◽

pp. 25

Author(s):

Dewi Nurhanifah ◽

Desy Noor Latifah Sari ◽

Rahmawati Rahmawati

Keyword(s):

Rank Test ◽

Purposive Sampling ◽

Signed Rank ◽

Wilcoxon Signed Rank Test ◽

Signed Rank Test

Salah satu masalah kesehatan yang sering dialami adalah penyakit gastritis. Gejala yang sering dikeluhkan oleh penderita gastritis adalah mual. Salah satu penatalaksanaan keperawatan yang dapat mengurangi rasa mual adalah tirah baring. Penelitian ini bertujuan untuk mengetahui pengaruh tirah baring terhadap penurunan rasa mual pada klien gastritis di Pelayanan Kesehatan. Metode penelitian menggunakan eksperimental dengan bentuk penelitian one group pretest-posttest design. Populasi dan sampel adalah klien yang mengalami mual di Wilayah Kerja Puskesmas yang berjumlah 15 orang. Sampel diambil dengan teknik purposive sampling. Alat pengumpul data menggunakan observasi. Analisa data melalui uji Wilcoxon Signed Rank Test. Hasil penelitian menujukkan klien gastritis sebelum tirah baring mengalami mual ringan sebanyak 7 orang (46,7%), sesudah tirah baring mengalami tidak mual sebanyak 7 orang (46,7%). Ada pengaruh tirah baring terhadap penurunan rasa mual pada klien gastritis di Pelayanan Kesehatan (ρ value = 0,001).

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