Terpenoids as Renewable Nano-Sized Building Blocks
Terpenoids are a large and structurally group of natural products containing multiple five carbon containing isoprene units. Previously we have reported that irrespective of their acyclic or alicyclic nature, all the triterpenoids containing 30C’s have nano-metric lengths. In the current studies, detailed computations have been carried out with 120 naturally occurring mono- (C10), sesqui- (C15), di- (C20), sester- (C25), sesqua- (C35) and tetra- (C40) terpenoids using Gaussian 09 software with Gauss view 07 and molecular mechanics calculation using Serena software. The heat of formation and the calculated molecular lengths obtained by the two methods were compared. Interestingly, monoterpenoid to tetraterpenoid all the terpenoids (except three monoterpenoid and one sesqui-terpenoid) have molecular lengths above one nanometer making them useful as nano-sized building blocks.