Bartonellosi e D-dimero

2021 ◽  
Vol 24 (10) ◽  
pp. 298-303
Author(s):  
Michela Licitra ◽  
Gabriela Acucella ◽  
Michelangelo Barbaglia ◽  
Paolo Mazzocchi ◽  
Gaetano Bottari ◽  
...  
Keyword(s):  
Bartonella Henselae ◽  
Abdominal Ultrasound ◽  
Ultrasound Scan ◽  
Persistent Fever ◽  
The Family ◽  
D Dimer

The paper reports the case of a 17-year-old immunocompetent boy with persistent fever and elevated D-dimer. The family referred contact with kitten and ingestion of homemade deer salami. Abdominal ultrasound scan and CT showed multiple hepatic and splenic abscesses. High levels of antibody title for Bartonella henselae confirmed the diagnosis of hepatosplenic bartonellosis.

Abdominal ultrasound scan in Down Syndrome patients: High frequency of nonsymptomatic biliary tract disease

1993 ◽  
Vol 46 (5) ◽  
pp. 612-612 ◽  
Author(s):  
Juan C. Llerena ◽  
Raquel Boy ◽  
João Barbosa Neto ◽  
Fernando Vargas ◽  
Clarisse Fontana ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Biliary Tract ◽  
High Frequency ◽  
Biliary Tract Disease ◽  
Abdominal Ultrasound ◽  
Ultrasound Scan ◽  
Tract Disease

scholarly journals Identification, Cloning, and Expression of the CAMP-Like Factor Autotransporter Gene (cfa) of Bartonella henselae

2005 ◽  
Vol 73 (7) ◽  
pp. 4205-4213 ◽  
Author(s):  
Christine M. Litwin ◽  
Joel M. Johnson
Keyword(s):  
Amino Acid ◽  
Bartonella Henselae ◽  
Polyacrylamide Gel Electrophoresis ◽  
Sodium Dodecyl ◽  
Cloning And Expression ◽  
Cosmid Library ◽  
Group B Streptococci ◽  
Reading Frame ◽  
Calculated Molecular Weight ◽  
The Family

ABSTRACT The CAMP reaction was first described by Christie et al. (R. Christie, N. E. Atkins, and E. Munch-Petersen, Aust. J. Exp. Biol. 22:197-200, 1944) as the synergistic lysis of sheep red blood cells by Staphylococcus aureus sphingomyelinase and CAMP factor (cohemolysin), a secreted protein from group B streptococci. We observed a CAMP-like reaction when Bartonella henselae was grown in close proximity to S. aureus on 5% sheep blood agar. This study describes the cloning, sequencing, and characterization of a CAMP-like factor autotransporter gene (cfa) from B. henselae. A cosmid library of B. henselae ATCC 49793 was constructed using SuperCos1 in Escherichia coli XL1-Blue MR. Cosmids were screened for the CAMP reaction, and a quantitative cohemolysis microtiter assay was developed using purified sphingomyelinase. Cosmid clones with the strongest cohemolytic reaction had similar restriction enzyme patterns. A DNA fragment that expressed the cohemolysin determinant was subcloned in a 7,200-bp StuI-BamHI fragment which contained a 6,024-bp open reading frame. The deduced amino acid sequence showed homology to the family of autotransporters. The autotransporters are a group of proteins that mediate their own export through the outer membrane. They contain an N-terminal passenger region, the α-domain, and a C-terminal transporter region, the β-domain. The α-domain contained four, nearly identical 42-amino-acid repeats and showed homology to the family of RTX (repeat in toxin) hemolysins. The concentrated supernatant of the recombinant strain expressed a protein with a molecular mass of 180 kDa on sodium dodecyl sulfate-polyacrylamide gel electrophoresis consistent with the calculated molecular weight of the secreted α-domain. In conclusion, we have characterized a novel secreted cohemolysin autotransporter protein of B. henselae.

scholarly journals Dent disease

2008 ◽  
Vol 136 (Suppl. 4) ◽  
pp. 312-315
Author(s):  
Snezana Pavicevic ◽  
Radovan Bogdanovic ◽  
Michael Ludwig ◽  
Mira Samardzic
Keyword(s):  
Renal Failure ◽  
Renal Damage ◽  
Abdominal Ultrasound ◽  
Tubular Reabsorption ◽  
Dent Disease ◽  
Low Molecular Weight ◽  
Clcn5 Gene ◽  
The Family ◽  
Proximal Tubulopathy ◽  
Beta 2 Microglobulin

INTRODUCTION. Dent disease is X-linked recessive proximal tubulopathy, due to mutations in the CLCN5 gene. It is characterized by low molecular weight proteinuria, hypercalciuria, nephrocalcinosis and progressive renal failure. CASE OUTLINE. A seven-year-old boy was referred after endocrinological examination where abdominal ultrasound showed nephrocalcinosis. There were anamnestic data neither of oedema, macrohaematuria, nor polyuria or hypertension. There were also no data of chronic renal failure in the family. We determined: proteinuria (1.8 g/day), elevated urinary excretion of Beta 2 microglobulin, microscopic haematuria, hypercalciuria (8-10 mg/kg/day), nephrocalcinosis, decreased tubular reabsorption phosphate (65%). Values of growth hormone, parathormone on thyroid hormone were normal. Except hypercalciuria, which was registered in the patient?s mother, all other analyses performed in family members were betwen reference values. Diagnosis was finalized by mutation analysis, which showed S244L substitution on CNCL5. Mutation carrier was mother with normal phenotype. CONCLUSION. Dent disease is rare X-linked nephrocalcinosis. Definitive diagnosis of this proximal tubulopathy which leads to progressive renal damage is not possible without evidence of gene mutation in renal chlorine channel.

Detection of liver involvement in inflammatory bowel disease by abdominal ultrasound scan

1992 ◽  
Vol 21 (2-4) ◽  
pp. 314-317 ◽  
Author(s):  
Cristina de Fazio ◽  
Giuseppe Torgano ◽  
Roberto de Franchis ◽  
Gianmichele Meucci ◽  
Mariateresa Arrigoni ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Abdominal Ultrasound ◽  
Liver Involvement ◽  
Ultrasound Scan ◽  
Inflammatory Bowel

scholarly journals AB010. S010. Pancreatic cystic lesions’ follow-up with abdominal ultrasound scan: could it play an alternative role to the routine use of MRI?

2018 ◽  
Vol 1 (1) ◽  
pp. AB010-AB010
Author(s):  
Simone Guadagni ◽  
Roberta Pisano ◽  
Valerio Borrelli ◽  
Gregorio Di Franco ◽  
Matteo Palmeri ◽  
...  
Keyword(s):  
Abdominal Ultrasound ◽  
Cystic Lesions ◽  
Ultrasound Scan

scholarly journals Neurological findings in a patient with mosaic chromosome 8 trisomy

2021 ◽  
Author(s):  
Bruno Custódio Silva ◽  
Thais Vanessa Salvador ◽  
Jéssica Karine Hartmann ◽  
Laira Francielle Ferreira Zottis ◽  
Mateus Arenhardt de Souza ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Abdominal Ultrasound ◽  
Chromosome 8 ◽  
Computed Tomography Scan ◽  
Cardiac Volume ◽  
The Family ◽  
Normal Chest ◽  
Bilateral Congenital Cataract ◽  
The Right ◽  
Tomography Scan

Context: Mosaic chromosome 8 trisomy is a rare genetic disease that can develop with neurological abnormalities. Case report: A male patient had a deficit in weight gain since his first month of life, in addition to delayed speech and neuropsychomotor. At 2 years old, the family noticed that he did not see well, and then began an ophthalmological investigation that resulted in the diagnosis of bilateral congenital cataract. Moreover, it was observed that the child had microcephaly, epicanthus, and strabismus converging to the right. Abdominal ultrasound showed hepatosplenomegaly and asymmetric kidneys. Computed tomography scan of the skull was normal. Chest radiography showed an increase in cardiac volume. Bone scintigraphy revealed heterogeneous uptake of the tracer radius in the projection of the femoral diaphyses, in addition to bilateral distal femoral hypertension, with central hypoactivity being more evident on the left. Blood karyotype exhibited a mosaic chromosome 8 trisomy (mos 47, XY, + 8 [10] / 46, XY [12]). His first medullogram had been normal; however, the new test showed myelodysplasia. Conclusions: Mosaic chromosome 8 trisomy is a chromosomal abnormality characterized by quite varied clinical manifestations. Neurological changes may be present, among which are seizures. There is also a description of agenesis of the corpus callosum. In our case, speech and neuropsychomotor delay was noteworthy.

scholarly journals Incidence of Invasive Fungal Infection (IFI) in ACUTE Myeloid Leukemia (AML) on Primary Prophylaxis with Voriconazole in Tertiriary Care Center in Pakistan

Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 42-42
Author(s):  
Shazia Riaz ◽  
Maria Saeed ◽  
Ahmed Imran
Keyword(s):  
Fungal Infection ◽  
Conflicts Of Interest ◽  
Fungal Infections ◽  
Care Center ◽  
Abdominal Ultrasound ◽  
Primary Prophylaxis ◽  
Hematologic Malignancies ◽  
Developed Countries ◽  
Persistent Fever ◽  
Institutional Review

OBJECTIVE: The aim of this study was to establish the incidence of IFI in AML patients receiving voriconazole prophylaxis in developing country. METHOD: This prospective study was conducted at The Children's Hospital, Lahore from July 2019 to December 2019 under Prospective AML registry approved by Institutional Review Board. All, consecutive patients of AML, either newly diagnosed or previously diagnosed cases with persistent fever and prolonged neutropenia, were included. Moreover, all patients of AML receiving chemotherapy also received voriconazole prophylaxis. Data of 64 patients was computed in accordance with age, gender, FAB classification, chemotherapy regimen and anti-fungal therapy. EORTC/MSG criteria was used to determine and classify IFI as proven, probable, or possible after performing CT chest and PNS, x-ray PNS, and abdominal ultrasound. CT scan was independently reviewed by a trained radiologist. Data was analyzed by SPSS version 22. RESULTS: Total 64 patients of AML were included in the study. The mean age of presentation was 6 years, range 1.5years to 16 years with 45 % males. Out of 64 patients, fungal infection was suspected in 50 patients (78%) due to persistent fever and prolonged neutropenia. In suspected 50 patients, probable and possible fungal infections were found in 22(34.37%) Patients. Eighteen 18/22 (81.81 %) were probable and 4/22 (18.18 %) were possible fungal infection. Majority of the cases 13/22 (59%) patients developed fungal infection during or after course of first induction therapy. CONCLUSION: Patients with high-risk hematologic malignancies especially AML are more at risk to develop IFI. In our study despite primary prophylaxis with voriconazole, incidence was higher than that reported in the literature from developed countries. Our data suggests that there is need to further improve supportive care measures and implement IFI preventive measures to decrease the incidence of IFI and improve survival. Disclosures No relevant conflicts of interest to declare.

scholarly journals Ultrasound and Risk Survey Evidence for Cystic Echinococcosis in La Rioja Province, Argentina

2021 ◽  
Author(s):  
Héctor Danoy Villa Micó ◽  
R. Salomé Ranalli ◽  
Lara Estefanía Hoffmann ◽  
Hugo Eduardo Bazán
Keyword(s):  
Confidence Interval ◽  
Rural Community ◽  
Cystic Echinococcosis ◽  
Ultrasound Examination ◽  
Abdominal Ultrasound ◽  
Ultrasound Images ◽  
Family Risk ◽  
Worldwide Distribution ◽  
The Family ◽  
La Rioja

Hydatidosis is a zoonosis of worldwide distribution with endemic areas in Argentina. The present epidemiological study was conducted to explore the presence of cystic echinococcosis in the rural community of Los Bordos (population 99), in the northern province of La Rioja, Argentina, during March 2018. The study included the search for cysts by abdominal ultrasound and a survey on family risk. Sixty-seven people agreed to undergo ultrasound examination, and five adults showed images compatible with hydatic cysts (7.5% prevalence). A family survey was applied to 29 households (78%), stratifying 24 families (83%) as high risk (95% confidence interval = 64.2–94.1) and 5 (17%) as low risk (95% confidence interval = 5.8–55.7) of transmission of the disease, respectively. The values were statistically different by the McNemar test. The goal of the present study, the first study of its kind in La Rioja, was to assess the family risk of echinococcosis among subjects with ultrasound images compatible with cystic echinococcosis.

scholarly journals Multiple contractures and their relationship with congenital amyoplasia

2021 ◽  
Author(s):  
Bruno Custódio Silva ◽  
Tainá Alano ◽  
Lennon Vidori ◽  
Paulo Ricardo Gazzola Zen ◽  
Rafael Fabiano Machado Rosa
Keyword(s):  
Abdominal Ultrasound ◽  
Clinical Findings ◽  
Radiographic Evaluation ◽  
Skeletal Musculature ◽  
The Family ◽  
History Of ◽  
Vertebral Bodies ◽  
The Right ◽  
Bone Structures ◽  
Nevus Flammeus

Context: Congenital amyoplasia is characterized by contractures (arthrogryposis) involving multiple large joints. Case report: The patient is a couple’s first daughter and no history of similar cases in the family. She was born at term, by cesarean delivery, weighing 3080 grams and with Apgar scores of 8 and 9. Gestational ultrasound revealed fetal akinesia, oligodramnia, and altered fetal skeletal musculature with shortening of the four limbs. During delivery, she suffered a fracture of the right femur. The patient evolved with a delay in neuropsychomotor development. On physical examination, hypotonia, nevus flammeus on the forehead, contractures involving several joints (including fingers, elbows, hips, knees and feet) were observed as well as pits in elbows and knees. Computed tomography scan of the skull showed cortical hypoplasia. Radiographic evaluation showed levoconvex thoracolumbar scoliosis and congenital changes in vertebral bodies of the thoracic spine, and thinning bone structures of the upper limbs. In addition, there were dysplastic acetabular, signs of constriction or tissue band in distal third of the right and middle thighs of the left, intense muscular hypotrophy, thinning of diaphysis of the femurs and echinovirus feet. Abdominal ultrasound and karyotype were normal. Conclusions: The clinical findings were compatible with those of congenital amyoplasia. Fetal akinesia or hypokinesia is a finding widely reported by mothers of children with this condition, as occurred in our case. Therefore, early interventions are very important, in order to avoid, in particular, greatest atrophy of the affected limbs, in addition to osteopenia.

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