scholarly journals Baseline Infection Burden and Cognitive Function in Elders with Essential Tremor

2021 ◽  
Vol 11 (1) ◽  
pp. 16
Author(s):  
Daniella Iglesias Hernandez ◽  
Silvia Chapman ◽  
Keith Radler ◽  
Hollie Dowd ◽  
Edward D. Huey ◽  
...  
Neurology ◽  
2006 ◽  
Vol 66 (1) ◽  
pp. 69-74 ◽  
Author(s):  
J. Benito-Leon ◽  
E. D. Louis ◽  
F. Bermejo-Pareja ◽  

2016 ◽  
Vol 366 ◽  
pp. 240-245 ◽  
Author(s):  
Elan D. Louis ◽  
Kathleen Collins ◽  
Brittany Rohl ◽  
Sarah Morgan ◽  
Daphne Robakis ◽  
...  

2018 ◽  
Vol 44 (2) ◽  
pp. E8 ◽  
Author(s):  
Na Young Jung ◽  
Chang Kyu Park ◽  
Won Seok Chang ◽  
Hyun Ho Jung ◽  
Jin Woo Chang

OBJECTIVEAlthough neurosurgical procedures are effective treatments for controlling involuntary tremor in patients with essential tremor (ET), they can cause cognitive decline, which can affect quality of life (QOL). The purpose of this study is to assess the changes in the neuropsychological profile and QOL of patients following MR-guided focused ultrasound (MRgFUS) thalamotomy for ET.METHODSThe authors prospectively analyzed 20 patients with ET who underwent unilateral MRgFUS thalamotomy at their institute in the period from March 2012 to September 2014. Patients were regularly evaluated with the Clinical Rating Scale for Tremor (CRST), neuroimaging, and cognition and QOL measures. The Seoul Neuropsychological Screening Battery was used to assess cognitive function, and the Quality of Life in Essential Tremor Questionnaire (QUEST) was used to evaluate the postoperative change in QOL.RESULTSThe total CRST score improved by 67.3% (from 44.75 ± 9.57 to 14.65 ± 9.19, p < 0.001) at 1 year following MRgFUS thalamotomy. Mean tremor scores improved by 68% in the hand contralateral to the thalamotomy, but there was no significant improvement in the ipsilateral hand. Although minimal cognitive decline was observed without statistical significance, memory function was much improved (p = 0.031). The total QUEST score also showed the same trend of improving (64.16 ± 17.75 vs 27.38 ± 13.96, p < 0.001).CONCLUSIONSThe authors report that MRgFUS thalamotomy had beneficial effects in terms of not only tremor control but also safety for cognitive function and QOL. Acceptable postoperative changes in cognition and much-improved QOL positively support the clinical significance of MRgFUS thalamotomy as a new, favorable surgical treatment in patients with ET.


2010 ◽  
Vol 43 (9) ◽  
pp. 45
Author(s):  
LEANNE SULLIVAN
Keyword(s):  

2011 ◽  
Vol 7 (7) ◽  
pp. 13
Author(s):  
MICHELE G. SULLIVAN

Author(s):  
C Fusco ◽  
J Valls-Solé ◽  
C Iturriaga ◽  
J Colomer ◽  
E Fernández-Alvarez

GeroPsych ◽  
2011 ◽  
Vol 24 (2) ◽  
pp. 83-92 ◽  
Author(s):  
Valentina A. Tesky ◽  
Christian Thiel ◽  
Winfried Banzer ◽  
Johannes Pantel

To investigate the effects of leisure activities on cognitive performance of healthy older subjects, an innovative intervention program was developed. Frequent participation in cognitively stimulating activities (i.e., reading, playing chess, or playing music) is associated with reduced risk of dementia. AKTIVA (active cognitive stimulation – prevention in the elderly) is an intervention program designed to enhance cognitive stimulation in everyday life by increasing cognitive stimulating leisure activities. The present study determines the effects of AKTIVA on cognitive function, mood and attitude toward aging in a sample of older participants from the general population. Several measurement instruments were used including the Alzheimer’s Disease Assessment Scale (ADAS-Cog), the Trail-Making Test (TMT), and the Memory Complaint Questionnaire (MAC-Q). Initially, the sample consisted of 307 older persons (170 female, 72 ± 7 years). The intervention was evaluated with a randomized, controlled pre-post follow-up design. Participants were randomly assigned to one of three conditions: AKTIVA intervention (n = 126), AKTIVA intervention plus nutrition and exercise counseling (n = 84), no-intervention control group (n = 97). The AKTIVA intervention consisted of 8 weekly sessions and two booster sessions after a break of 4 months. Participation in the group program resulted in positive effects on cognitive function and attitude toward aging for subassembly groups. Older persons (≥ 75 years) showed enhanced speed of information processing (by TMT Version A) (F = 4.17*, p < .05); younger participants (< 75 years) showed an improvement in subjective memory decline (by MAC-Q) (F = 2.55*, p < .05). Additionally, AKTIVA enhanced the frequency of activities for leisure activities for subassembly groups. The results of this study suggest that the AKTIVA program can be used to increase cognitively stimulating leisure activities in the elderly. Further research is necessary to identify the long-term effects of this intervention particularly with respect to the prevention of dementia.


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