scholarly journals Clinicopathological Features of Carcinoma of Cervix

2021 ◽  
Vol 15 (7) ◽  
pp. 1785-1786
Author(s):  
Jawad Ali Memon ◽  
Zubair Ali Memon ◽  
Muhammad Sibtain Shah ◽  
Abdul Rasheed Baloch ◽  
Ali Akbar Nagraj
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Clinicopathological Features ◽  
Stage Ii ◽  
Carcinoma Cervix ◽  
College Hospital ◽  
Medical College ◽  
Carcinoma Of Cervix ◽  
Key Word ◽  
Time Of Presentation

Objective: To look at the age, stage at presentation, and morphology of cervix cancer patients. Study Design: Single institutional study. Place and Duration of Study:Department of Radiology, Peoples Medical College, Hospital, Nawabshah, Shaheed Benazirabad, and Sindh, Pakistan from January 1st 2018 to 31st December 2020. Methodology: Five hundred biopsy proven cases of carcinoma cervical cancer were enrolled and age at the time of presentation, histology, and stage after diagnosis were included. Results:68.4% females with cervical carcinoma were between the age of 40 to 59 years and majority of patients were belonged to the rural area with (73.7%). 75.1% of the patients had squamous cell carcinomas, 3.3% had adenosquamous carcinomas, and 17.9% had adenocarcinomas. Female patients have been stratified by stage of the disease in which 46.2 % belongs to the stage II. Conclusion: Majority of females have squamous cell carcinoma predominance over ardenosquamous carcinoma and adenocarcinoma and stage II was the most common in the females with carcinoma of cervix. Key Word Carcinoma, Cervix, Squamous cell

scholarly journals Early detection of cervical intraepithelial lesions by simple visual inspection after acetic acid among women in Rajshahi medical college hospital

1970 ◽  
Vol 10 (4) ◽  
pp. 240-244 ◽  
Author(s):  
N Yusuf ◽  
F Islam ◽  
H Akhter ◽  
MA Ali ◽  
JA Khanam
Keyword(s):  
Visual Inspection ◽  
Invasive Carcinoma ◽  
Final Diagnosis ◽  
Epidemiological Studies ◽  
College Hospital ◽  
Medical College ◽  
Cervical Intraepithelial Lesions ◽  
Carcinoma Of Cervix ◽  
History Of ◽  
Intraepithelial Lesions

Aim: To evaluate the performance of visual inspection of acetic acid (VIA) in the detection of precancerous and early cancerous lesions of cervix. Materials and methods: Total 5593 eligible women who randomly came to the Gyenae out patient department (OPD) of RMCH (Rajshahi Medical College Hospital) were examined by VIA. Detection of well defined, opaque, acetowhite lesions close to the squamocolumner junction or in transitional zone or dense acetowhitening of ulceroproliferative growth on the cervix constituted a positive VIA. Those who had abnormal results in screening test & those who had clinically suspicious lesions were sent for colposcopic evaluation (n= 442) & directed biopsy were taken from colposcopically suspected areas (n=214). The final diagnosis was based on histology. Results: Out of 5593 patients, 442 (7.20%) were VIA positive. 442 patients were colposcopically evaluated .Among them, 228 (51.58%) were normal and 202(45.70%) had different stages of cervical intraepithelial lesions (CIN) and 12 ( 2.71 % ) had carcinoma of cervix. Out of 214 patients biopsied, 23.36 % patients had a final diagnosis of CIN lesions, 5 (2.33%) had carcinoma in-situ & 17 cases (7.94%) had invasive carcinoma. Besides to find out the predictable factors of cervical lesions data have been collected from VIA positive patients regarding age of first coitus and first delivery, history of extra marital exposure and STI, use of contraceptive methods and family history of cancer. Age of first coitus between 12 to 15 years and 16 to 20 years were observed among 203 (46 %) and 40 % (177) women respectively. More than half of the patients (62%) were experienced with their first delivery within the age 15-20 years which was below 15 years of 12 % (53) patients. Fifty four percent patients used OCP and barrier methods used were only 10 %. Family history of cancer was observed among 09 % women. 58% patients were belonged to lower middle class and upper group were only 9% (table 1) Conclusion: In our study detection of different grades of intraepithelial lesions (CIN-I, CIN-II, CIN-III, invasive carcinoma) of cervix by VIA was comparable to that of colposcopy. So VIA is suitable for detection of precursor lesions of cervical cancer in low resource settings and also for diagnosis, follow up treatment and epidemiological studies of cervical cancer. Key words: Visual inspection; VIA; cervical carcinoma; colposcopy; screening; epidemiological studies. DOI: http://dx.doi.org/10.3329/bjms.v10i4.9494 BJMS 2011; 10 (4): 240-244

scholarly journals Cytologic and colposcopic evaluation of all symptomatic women at tertiary care centre

2017 ◽  
Vol 4 (3) ◽  
pp. 799
Author(s):  
Richa Garg ◽  
Ranjana Desai
Keyword(s):  
Prospective Observational Study ◽  
Pap Smear ◽  
Invasive Carcinoma ◽  
Tertiary Care ◽  
Care Centre ◽  
Carcinoma Cervix ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Carcinoma Of Cervix ◽  
Malignant Lesions

Background: Cervical cancer in India ranks as the 2nd most frequent cancer among women and the 2nd most frequent cancer among women between 15 and 44 years of age. Invasive carcinoma of cervix is preventable as it is associated with pre-invasive stage which occurs 10-15 years prior to it, thus permitting early detection by screening and leading to effective treatment and thereby reducing mortality rate with greater impact on lives saved. Objectives were to correlate the findings of Pap smear with colposcopy in evaluation of all symptomatic women; and to assess the utility of colposcopy in detecting the premalignant and malignant lesions of cervix.Methods: This was a prospective observational study of 200 symptomatic women attending the Gynecology OPD of Umaid Hospital Dr. S. N. Medical College Jodhpur, Rajasthan, India from February 2015 to October 2016. Evaluation of all symptomatic women done with Pap smear, colposcopy and biopsy in selected cases and findings were noted.Results: Commonest complaint was white discharge per vaginum in 58.5% followed by pelvic pain in 24% women. 8% women had abnormal pap smear findings with 4% of women had ASCUS, 0.5% had ASC-H, 3% had LSIL and 0.5% had HSIL,73% had inflammatory and 19% with normal smear. 38.5% had abnormal colposcopy with maximum 28% women had acetowhite lesions. Sensitivity of pap smear was 44.44% while sensitivity of colposcopy was 88.88%.Conclusions: Pap smear had poor sensitivity as compared to colposcopy. Hence simultaneous use of colposcopy has shown to increase in the rate of carcinoma cervix detection in symptomatic women.

scholarly journals Pattern of Histopathologically Confirmed Uterine and Ovarian Anomeli Among 98 Hysterectomies Attending a Private Medical College Hospital, Dhaka

2017 ◽  
Vol 8 (1) ◽  
pp. 6-9
Author(s):  
Tabassum Tahmin Sajani ◽  
Tanjila Tahmin Sarnali ◽  
Md Atiqur Rahman ◽  
Shoib Ahmed
Keyword(s):  
Histopathological Examination ◽  
Developed Countries ◽  
Age Group ◽  
Pathological Findings ◽  
Carcinoma Cervix ◽  
College Hospital ◽  
Medical College ◽  
Total Hysterectomy ◽  
Gynecological Disorders ◽  
Chronic Cervicitis

Background: Endometrial diseases ranked among the most common gynecological disorders that affect women globally. This study was undertaken to identify the most common pathologies identified in hysterectomy specimens.Materials & Methods: The present study was conducted in the Department of Pathology, Anwer Khan Modern Medical College, Dhaka over a period of 6 months from July to December 2013. Ninety eight (98) hysterectomy specimens were received by the pathology department during this period. On receiving the hysterectomy specimens, the gross features were noted. A detailed microscopic examination was done to arrive at an accurate diagnosis.Result: Most of the women 54% were 40-49 years age group followed by 25% in 30-39 years age group. Chronic cervicitis and adenomyosis were the commonest pathological findings in (80.6%) and (32.7%) respectively. Other pathologies identified include Leiomyoma (23.5%), endometrial hyperplasia (17.4%), endometrial polyp (4.1%) and PID with hemorrhagic infection (1.0%). Two cases of carcinoma cervix (2.0%), two local invasion of tumors (2.0%) and one adenocarcima (1.0%) was found. Type of operation most common is total hysterectomy with oophorectomy (51.0%).Conclusion: Hysterectomy still remains the widely used treatment modality even in developed countries. The ultimate diagnosis is only on histology, so every hysterectomy specimen should be subjected to histopathological examination. Benign pathologies are more common than their malignant counterparts and the most common pathologies identified in hysterectomy specimens are chronic cervicitis, adenomyosis and leiomyoma.Anwer Khan Modern Medical College Journal Vol. 8, No. 1: Jan 2017, P 6-9

Prognostic potential of CK-19 managing disseminated oral squamous cell carcinomas in Pakistan: A descriptive cross-sectional study

2020 ◽  
pp. 1-13
Author(s):  
Waqas Iqbal ◽  
Uzma Tariq ◽  
Arhama Surwaich ◽  
Surwaich Ali channa ◽  
Abdul Majid ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cross Sectional Study ◽  
Squamous Cell Carcinomas ◽  
Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Oral Squamous Cell Carcinomas

Abstract A cross-sectional study was conducted to assess the adoptability of CK-19 as a routine diagnostic assay and potential prognostic marker following disseminated oral squamous cell carcinoma in Pakistani population. The current descriptive study was conducted at Isra Dental College Hospital, Isra University, Hyderabad, Pakistan. Suspected patients of oral squamous cell carcinomas (OSCC), who visited the Isra Dental College Hospital’s outpatient department from January 2014 up to January 2015 with four year follow up (from January 2015 up to December 2019), were included after ethical approval of the Institutional board. SPSS version 21.0 was used for data analysis. Sixty cases of oral squamous cell carcinoma (OSCC) were selected for CK-19 quantification by using PCR before and after incisional biopsy.    

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