scholarly journals The Isambert disease: a very rare revelation of miliary tuberculosis

Author(s):  
Z Rachadi ◽  
M Idalene ◽  
L Arsalane ◽  
A Raji ◽  
N Tassi

The objective of this study was to report a case of miliary tuberculosis revealed by a pharyngeal localization, and study this disease through a literature review.We report the clinical case of a 23 year old patient presented for chronic tonsillitis treated as bacterial but without improvement. Dysphonia and dysphagia were added later with the same signs of tuberculous impregnation. The chest x-ray done before the onset of coughing had objectified miliary. The diagnosis of tuberculosis was selected before the detection of acid-fast bacilli in cytobacteriological examination of the pharyngeal swab and sputum. Specific antituberculous treatment led to a favourable outcomeIn a context of endemic tuberculosis, the diagnosis of miliary tuberculosis of the pharynxshould be considered in all pharyngeal syndrome did not improve with medical treatment.Keywords: Isambert disease; oropharynx ; tuberculosis

2014 ◽  
Vol 13 (3) ◽  
pp. 200-203
Author(s):  
Renatas Aškinis ◽  
Arnoldas Krasauskas ◽  
Sigitas Zaremba ◽  
Saulius Cicėnas

Neurilemoma – periferinių nervų dangalų auglys. Jis auga lėtai ir pradžia dažniausiai būna besimptomė. Pasiekęs kritinį dydį auglys, priklausomai nuo atsiradimo vietos, pasireiškia spaudimo į aplinkinius organus klinika. Neurilemomos dažniausiai atsiranda galūnėse 30–50 gyvenimo metais nepriklausomai nuo lyties. Klajoklio nervo neurilemoma yra nedažna patologija, o krūtininės klajoklio nervo dalies neurilemoma pasitaiko itin retai. Diagnozuojant svarbiausi yra radiologiniai tyrimo metodai. Gydymas – chirurginis auglio pašalinimas. Pateikiame krūtininės klajoklio nervo dalies neurilemomos, nustatytos 39 metų moteriai, klinikinį atvejį. Auglys aptiktas radiologiniais tyrimais (krūtinės rentgeno, kompiuterinės tomografijos ir tarpuplaučio magnetinio branduolių rezonanso), pašalintas naudojant vaizdo torakoskopinę (VATS) metodiką. Diagnozė galutinai patvirtinta histologiniu tyrimu. Aštuntą parą po operacijos ligonė išrašyta į namus.Reikšminiai žodžiai: neurilemoma, klajoklis nervas, operacija Neurilemoma of intrathoracal vagal nerve: clinical caseRenatas Aškinis, Arnoldas Krasauskas, Sigitas Zaremba, Saulius Cicėnas Neurilemoma is a tumour of peripleurical nervous tissues. It grows slowly and has an asymptomatic manifestation. During tumour enlargement, depending on localisation, clinical symptoms appear because of the tumour pressure to the surrounding tissues. Mostly neurilemomas appear in extremities of patients aged 30–50 years. N. vagus neurilemoma is a very rare disease. The diagnosis is made using radiology. The treatment is surgical removal. We present a clinical case of intrathoracal n. vagus neurilemoma in a 39-year-old woman. The diagnosis was made using radiological findings (chest X-ray, chest CT, and the MRI of the mediastinum). The removal of the tumour was made by VATS. The diagnosis was proved morphologically. After 8 days, the patient was discharged from the hospital.Key words: neurilemoma, vagal nerve, operation


2003 ◽  
Vol 61 (3B) ◽  
pp. 855-858 ◽  
Author(s):  
Emerson L. Gasparetto ◽  
Priscilla Tazoniero ◽  
Arnolfo de Carvalho Neto

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has the pulmonary form as the most common presentation. Dissemination of the disease is common in immunocompromised patients, but immunodeficiency related to pregnancy severe enough to cause dissemination of the Mycobacteria is exceedingly rare. When dissemination occurs, any organ may be affected and in central nervous system, the infection presents as meningitis and single brain parenchyma tuberculomas. We report the case of a 17 year-old woman at the 34th week of pregnancy with respiratory and high intracranial pressure symptoms. On the day before admission she had a sudden onset of paraparesis and urinary retention and ten hours after the delivery she presented with paraplegia . The chest X-ray and CT scan were compatible with miliary tuberculosis. The cranial CT scan revealed numerous rounded hypodense lesions located at cerebral and cerebellar hemispheres, which presented ring-like enhancement after contrast injection. The patient underwent a craniotomy with biopsy of the lesions confirming the diagnosis of brain tuberculomas. The three-drug regimen was started and the cranial CT scan performed a year after diagnosis showed no brain lesions. We emphasize the aggressive dissemination of the disease in this case associated with pregnancy and the importance of early diagnosis and institution of therapy resulting in regression of the lesions.


2020 ◽  
Vol 10 (1) ◽  
pp. 17-20
Author(s):  
Z. Nadiah ◽  
R. C. Koesoemadinata ◽  
S. M. McAllister ◽  
G. Putriyani ◽  
L. Chaidir ◽  
...  

Adult presumptive tuberculosis (TB) patients (n = 1690) were screened for TB using a questionnaire, chest X-ray (CXR) and sputum microscopy for acid-fast bacilli (AFB); <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> culture was performed for 74% of the patients and Xpert® MTB/RIF was done for 17.2%. Among patients recruited, 943 (55.8%) were diagnosed with TB, of whom 870 (92.3%) were bacteriologically confirmed and 73 (7.7%) were clinically diagnosed on the basis of CXR. Using CXR prior to culture or Xpert testing reduces the number needed to screen from 7.6 to 5.0. Using CXR to triage for culture or Xpert testing reduces the number of missed cases and increases the efficiency of culture and Xpert testing.


2012 ◽  
Vol 11 (3-4) ◽  
pp. 89-92
Author(s):  
Renatas Aškinis ◽  
Arnoldas Krasauskas ◽  
Sigitas Zaremba ◽  
Saulius Cicėnas

Neurilemoma – periferinių nervų dangalų auglys, kuris auga lėtai ir jo pradžia dažniausiai būna besimptomė. Pasiekę kritinį dydį augliai, priklausomai nuo atsiradimo vietos, pasireiškia spaudimo į aplinkinius organus klinika. Neurilemomos dažniausiai atsiranda galūnėse 30–50-ais gyvenimo metais ir nuo lyties nepriklauso. Klajoklio nervo neurilemoma yra nedažna patologija, o krūtininės klajoklio nervo dalies neurilemoma pasitaiko itin retai. Diagnostikai svarbiausi yra radiologiniai tyrimo metodai. Gydymas – chirurginis auglio šalinimas. Pateikiame krūtininės klajoklio nervo dalies neurilemomos, nustatytos 39 metų moteriai, klinikinį atvejį. Auglys aptiktas radiologiniais tyrimais (krūtinės rentgeniniu, kompiuterinės tomografijos ir tarpuplaučio magnetinio branduolių rezonanso), pašalintas naudojant vaizdo torakoskopinę metodiką. Diagnozė galutinai patvirtinta histologiniu tyrimu. Aštuntą parą po operacijos ligonė išrašyta į namus.Reikšminiai žodžiai: neurilemoma, klajoklis nervas, operacija.Neurilemoma of intrathoracal vagal nerve: case report Neurilemoma is a tumour of peripleurical nervous tissues. It grows slowly and has an asymptomatic manifestation. During tumour enlargement, depending on its localization, clinical symptoms appear due to the tumour pressure to surrounding tissues. Neurilemomas mostly appear in the extremities of patients aged 30–50 years. N. vagus neurilemoma is a very rare disease. The diagnosis is made using radiology. Its treatment is surgical removal. We present a clinical case of intrathoracal nervus vagus neurilemoma in a 39-y woman. The diagnosis was based on radiological findings (chest X-ray, chest CT, and mediastinum MRI). The removal of the tumour was made by the VATS method. The diagnosis was proven morphologically. After 8 days the patient was discharged from the hospital.Key words: neurilemoma, vagal nerve, operation.


2021 ◽  
Vol 9 (09) ◽  
pp. 122-127
Author(s):  
Yousra Oussou ◽  
◽  
Jihad Raoui ◽  
Siham Hallab ◽  
Latifa Oukerraj ◽  
...  

Hydatid cyst is a parasitic disease endemic in different regions of the world. Cardiac localization represents only 0.5 to 2% of all attacks, characterized by clinical, paraclinical and especially radiological polymorphism. Its spontaneous development is serious because of the risk of endocavity rupture. The diagnosis is facilitated by means of non-invasive imaging, in particular echocardiography, thoracic computed tomography and magnetic resonance imaging. Given the lack of alternative treatment options, cystectomy and pericystectomy are the only surgical techniques capable of offering chances of recovery with acceptable morbidity and mortality. Antiparasitic treatment comes in addition to surgery. Eradication of hydatid disease mainly involves effective collective and individual preventive measures. We present a clinical case of a 54-year-old patient who presented with asthenia followed by precordial pain, who has a normal EKG and chest x-ray. Transthoracic echocardiography (TTE) a mass that bulges in the lateral aspect of the left heart chambers. The thoracic tomodensitometry objectified a cystic image which bulges in the left cardiac chambers suggesting a cardiac hydatid cyst. A hypereosinophilia was objective in the biological assessment. The patient was sent to the cardiovascular surgery department for surgery. We present a clinical case of a 54-year-old patient who presented with asthenia followed by precordial pain, who has a normal EKG and chest x-ray. Transthoracic echocardiography (TTE) a mass that bulges in the lateral aspect of the left heart chambers. The thoracic tomodensitometry objectified a cystic image which bulges in the left cardiac chambers suggesting a cardiac hydatid cyst. A hypereosinophilia was objective in the biological assessment. The patient was sent to the cardiovascular surgery department for surgery. We present a clinical case of a 54-year-old patient who presented with asthenia followed by precordial pain, who has a normal EKG and chest x-ray. Transthoracic echocardiography (TTE) a mass that bulges in the lateral aspect of the left heart chambers. The thoracic tomodensitometry objectified a cystic image which bulges in the left cardiac chambers suggesting a cardiac hydatid cyst. A hypereosinophilia was objective in the biological assessment. The patient was sent to the cardiovascular surgery department for surgery. Transthoracic echocardiography (TTE) a mass that bulges in the lateral aspect of the left heart chambers. The thoracic tomodensitometry objectified a cystic image which bulges in the left cardiac chambers suggesting a cardiac hydatid cyst. A hypereosinophilia was objective in the biological assessment. The patient was sent to the cardiovascular surgery department for surgery. Transthoracic echocardiography (TTE) a mass that bulges in the lateral aspect of the left heart chambers. The thoracic tomodensitometry objectified a cystic image which bulges in the left cardiac chambers suggesting a cardiac hydatid cyst. A hypereosinophilia was objective in the biological assessment. The patient was sent to the cardiovascular surgery department for surgery.


2014 ◽  
Vol 13 (3) ◽  
pp. 200-203
Author(s):  
Renatas Aškinis ◽  
Arnoldas Krasauskas ◽  
Sigitas Zaremba ◽  
Saulius Cicėnas

Neurilemoma – periferinių nervų dangalų auglys. Jis auga lėtai ir pradžia dažniausiai būna besimptomė. Pasiekęs kritinį dydį auglys, priklausomai nuo atsiradimo vietos, pasireiškia spaudimo į aplinkinius organus klinika. Neurilemomos dažniausiai atsiranda galūnėse 30–50 gyvenimo metais nepriklausomai nuo lyties. Klajoklio nervo neurilemoma yra nedažna patologija, o krūtininės klajoklio nervo dalies neurilemoma pasitaiko itin retai. Diagnozuojant svarbiausi yra radiologiniai tyrimo metodai. Gydymas – chirurginis auglio pašalinimas. Pateikiame krūtininės klajoklio nervo dalies neurilemomos, nustatytos 39 metų moteriai, klinikinį atvejį. Auglys aptiktas radiologiniais tyrimais (krūtinės rentgeno, kompiuterinės tomografijos ir tarpuplaučio magnetinio branduolių rezonanso), pašalintas naudojant vaizdo torakoskopinę (VATS) metodiką. Diagnozė galutinai patvirtinta histologiniu tyrimu. Aštuntą parą po operacijos ligonė išrašyta į namus.Reikšminiai žodžiai: neurilemoma, klajoklis nervas, operacija Neurilemoma of intrathoracal vagal nerve: clinical caseRenatas Aškinis, Arnoldas Krasauskas, Sigitas Zaremba, Saulius Cicėnas Neurilemoma is a tumour of peripleurical nervous tissues. It grows slowly and has an asymptomatic manifestation. During tumour enlargement, depending on localisation, clinical symptoms appear because of the tumour pressure to the surrounding tissues. Mostly neurilemomas appear in extremities of patients aged 30–50 years. N. vagus neurilemoma is a very rare disease. The diagnosis is made using radiology. The treatment is surgical removal. We present a clinical case of intrathoracal n. vagus neurilemoma in a 39-year-old woman. The diagnosis was made using radiological findings (chest X-ray, chest CT, and the MRI of the mediastinum). The removal of the tumour was made by VATS. The diagnosis was proved morphologically. After 8 days, the patient was discharged from the hospital.Key words: neurilemoma, vagal nerve, operation


On an example of a clinical case in a patient with drug addiction, the reviewed clinical and chest X-ray features of community-acquired pneumonia, the diagnostic algorithms and the differential diagnostics are based on the recommendations of the Ukrainian Association of Pulmonology. The treatment strategy of the patient in the conditions of an ambulatory are described. Community-Acquired pneumonia acquired by intravenous drug use is characterized by a severe course, febrile body temperature, severe specific lung disease. On the example of this clinical case, the importance of express diagnostics of pneumonia at the ambulatory stage wasconfirmed to determine the correct tactics of patient management.


2017 ◽  
Vol 98 (2) ◽  
pp. 261-266
Author(s):  
M L Gorbunova ◽  
S N Volkova ◽  
G V Shestakova ◽  
E L Spiridonova

The article presents а description of our personal case of pulmonary and hepatic echinococcosis in a 38-years-old patient. Literature data on clinical presentation, laboratory and instrumental diagnostic methods of the disease are presented. Different variants of clinical presentation of pulmonary echinococcosis and its possible complications are described. The problems of differential diagnosis, surgical and conventional methods of treatment are analyzed. The presented clinical case confirms the wide spread opinion that the diagnosis of pulmonary echinococcosis based on only the results of chest X-ray is extremely challenging. Frequent diagnostic mistakes are associated with the primary diagnosis of pneumonia based on chest X-ray. Use of high-pitch spiral computed tomography implemented recently into clinical practice provides early differential diagnosis of pulmonary lesions with parasitic diseases, in particular, with echinococcosis. The final diagnosis is confirmed by serologic methods of echinococcosis diagnosis with the use of enzyme immunoassays.


2011 ◽  
Vol 139 (7-8) ◽  
pp. 514-517 ◽  
Author(s):  
Branislava Milenkovic ◽  
Aleksandra Dudvarski-Ilic ◽  
Goran Jankovic ◽  
Lena Martinovic ◽  
Dragana Mijac

Introdution. Tumour necrosis factor alpha (TNF?) has a central role in the host immune response to mycobacterial infection. TNF? blockade may therefore result in reactivation of recent or remotely acquired infection. In reported mycobacterium tuberculosis infections, extra-pulmonary and disseminated tuberculosis (TB) was common, appeared rapidly, and if unrecognized, with fatal outcome. We present a female patient with miliary TB following treatment with infliximab for fistulizing Crohn?s disease. Case Outline. Five years before admission, the patient was diagnosed with Crohn?s disease, with inflammation limited to the terminal ileum and sigmoid colon and has been on azathioprine 100 mg/day for the last 10 months. Three months before admission to the hospital she developed an enterocutaneous fistula for which therapy with infliximab was started in addition to azathioprine therapy. A tuberculin skin test and a chest x-ray were performed prior to the first infusion with normal findings. She presented with a 6-week history of fever, weakness, weight-loss and a 2-week dry cough. Chest x-ray and computed tomography displayed remarkable bilateral hilar and mediastinal lymphadenopathy and uniformly distributed fine nodules throughout both lung fields varying in size from 2 to 3 mm, without any signs of cavitation. Since there were clinical and morphological signs that indicated miliary TB, the treatment with antituberculous therapy was started and six weeks later all of the symptoms completely resolved and the lesions visible on x-ray diminished. Conclusion. The clinical use of TNF-inhibitors is associated with increased risk of developing tuberculosis. Physicians should be aware of the increased risk of reactivation of TB among patients treated with anti-TNF agents and regularly look for usual and unusual symptoms of TB.


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