Feminine intimate hygiene plants from Kinshasa / DR Congo: Potential source of contraceptive compounds

2021 ◽  
Vol 1 (1) ◽  
pp. 071-078
Author(s):  
Odette N Kabena ◽  
Jean Jacques D Amogu ◽  
Nadège K Ngombe ◽  
EJ Mboloko ◽  
Pius T Mpiana ◽  
...  
Keyword(s):  
Mangifera Indica ◽  
Human Sperm ◽  
Phytochemical Analysis ◽  
Dr Congo ◽  
Ethnobotanical Survey ◽  
Bridelia Ferruginea ◽  
Contraceptive Effect ◽  
Potential Source ◽  
Sperm Mobility ◽  
The One

This study is part of the promotion of local medicinal plants by highlighting their spermicidal activity. An ethnobotanical survey carried out in Kinshasa made it possible to identify the plants used in female intimate hygiene. On the one hand, the aqueous extracts of the organs of ten (10) plants on the inventoried species were subjected to a phytochemical analysis. On the other hand, the recipes as applied by women as well as the total extracts of these plants have come into contact with human sperm. The analysis of the mobility and the evaluation of the viability of the sperm of the ejaculates, of good quality according to the WHO, were carried out according to the methods of Sander-Cramer and that of Williams, respectively. Thus, the concentration (EC100) capable of killing 100% of sperm within 30 minutes of exposure was detected. Thirty-eight (38) plant species have been identified. From thirteen sought-after phytochemical groups, extracts of Mangifera indica and Bridelia ferruginea contain twelve and eleven respectively. Four (4) groups of metabolic compounds with a contraceptive effect are present in all ten extracts of feminine hygiene plants. Three (3) herbal recipes (Abrus precatorius, Bridelia ferruginea and Ocimum basilicum) out of the ten studied resulted in the cancellation of sperm mobility after 3 hours of exposure. And, the EC100 is defined at 200 mg/mL for A. precatorius and 25 mg / mL for B. ferruginea. The results of this study show that feminine intimate hygiene plants contain compounds with spermicidal potential, which can be used for the development of vaginal contraceptives.

scholarly journals PHYSICOCHEMICAL AND PHYTOCHEMICAL ANALYSIS OF Mangifera indica linn.( AAMRA KERNEL )

2020 ◽  
Vol p4 (05) ◽  
pp. 2394-2400
Author(s):  
Pooja Dogra ◽  
A. Rama Murthy ◽  
Sumit Nathani
Keyword(s):  
Mangifera Indica ◽  
Natural Antioxidants ◽  
Water Soluble ◽  
Phytochemical Analysis ◽  
Tropical Regions ◽  
Potential Source ◽  
Mango Kernel ◽  
Phytochemical Constituents ◽  
Phytochemical Studies

Introduction: Mangifera Indica Linn., Anacardiaceae family, is a large evergreen tree of tropical and sub-tropical regions of the world. Mango kernel can be used as a potential source for functional food ingredi-ents, animal feeds, antimicrobial compounds and cosmetic due to its high quality of fat and protein as well as high levels of natural antioxidants. Aim: The aim of the present study was to evaluate the physicochemical and phytochemical analysis of Mangifera Indica Linn. Methods Aamra Kernel were collected, cleaned, dried and powdered. Aqueous and alcoholic extracts of Aamra kernel were analyzed for physicochemical and phytochemical constituents. The study was conduct-ed as per the guidelines of Ayurvedic pharmacopeia of India. Results: The result of physicochemical parameters (moisture content: 10.2%, total ash: 2.12%, acid insolu-ble ash: 0.3%, water soluble ash: 1.42%, aqueous extractive value: 14.67% and alcoholic extractive value 12.98%). The phytochemical studies revealed the presence of active constituents, carbohydrates, amino acid, steroids, proteins, saponins, alkaloids, glycosides, tannins in aqueous and alcoholic extracts. Conclusion: All studies standardization parameters like physicochemical and phytochemical screening pa-rameters provide the knowledge in the identification, authentication of kernel of Mangifera Indica Linn. Hence it is concluded that this drug supposed to be great beneficial and boon for our society.

Survey of Medicinal Plants Used in the Management of Sickle Cell Disease by Traditional Medical Practitioners of Gbonyin Local Government Area of Ekiti State, Nigeria

2015 ◽  
Vol 19 ◽  
pp. 78-84
Author(s):  
TI Famojuro ◽  
JO Moody
Keyword(s):  
Sickle Cell Disease ◽  
Local Government ◽  
Medicinal Plants ◽  
Plant Species ◽  
Sickle Cell ◽  
Mangifera Indica ◽  
Local Government Area ◽  
Herbal Remedies ◽  
Cell Disease ◽  
Ethnobotanical Survey

Ethnobotanical survey was conducted on plants used traditionally for the management of sickle cell disease (SCD) in Gbonyin Local Government Area (LGA) of Ekiti State, South Western Nigeria. The study was conducted to document some of the medicinal plants used in the management of SCD with the aim of identifying possible drug leads from the phytomedicine of the area. A semi-structured questionnaire was used to obtain information on the use of herbal remedies for the management of SCD. A total of 32 respondents were interviewed in this study. twenty of them were males while twelve were females with the age range of 25 to 70 years. A total of 44 plant species belonging to 44 genera and 30 families were identified to be useful for the management of SCD. The most prominent among these plant families (genera) are Anacardiaceae (Anacardium occidentalis, Mangifera indica, Spondias mombin), Euphorbiaceae (Croton lobatus, Jatropha gossypifolia, Plukeneta conophora) and Fabaceae (Cajanus cajan, Pterocarpus osun, Cassia siamea) with three species each. Eighty percent (80%) of the 32 respondents interviewed said that their clients did not report any side effect and that the herbs were either collected from the forest (where available) or purchased from the herb markets. In all, the commonest plant species among the recipes given by the respondents according to their Use Mention Index (UMI) include: Elaeis guineense Jacq., Arecaceae (0.124); Khaya grandifoliola C.DC., Meliaceae (0.094); Carica papaya L., Caricaceae(0.094); Hymenocardia acida Tul., Phyllanthaceae (0.094); Mangifera indica L., Anacardiaceae (0.094); Parquetina nigrescens (Afzel.) Bullock, Asclepiadaceae (0.094) and Xylopia aethiopica (Dunal) A. Rich., Annonaceae (0.094).The main method of preparation is by decoction and in most cases, the preparation is taken orally twice to thrice daily. All the plants identified in this work have been used by most of the herbalists and adjudged to be efficacious in SCD management. The study concluded that the medicinal folklore of the Ekiti State LGA covered by this survey indicated high potential for drug discovery for the management of sickle cell disease.Keywords: Ethnobotany, Sickle Cell Disease, Traditional Medicine, Gbonyin LGA, Medicinal Plants

Antimalarial herbal remedies of Bukavu and Uvira areas in DR Congo: An ethnobotanical survey

2020 ◽  
Vol 249 ◽  
pp. 112422 ◽  
Author(s):  
Mboni Henry Manya ◽  
Flore Keymeulen ◽  
Jérémie Ngezahayo ◽  
Amuri Salvius Bakari ◽  
Mutombo Emery Kalonda ◽  
...  
Keyword(s):  
Herbal Remedies ◽  
Dr Congo ◽  
Ethnobotanical Survey

scholarly journals Antimicrobial and phytochemical analysis of leaves and bark extracts from Bridelia ferruginea

2010 ◽  
Vol 9 (7) ◽  
pp. 1031-1036 ◽  
Author(s):  
Owoseni ◽  
A Abimbola ◽  
Ayanbamiji ◽  
A T ◽  
Ajayi ◽  
...  
Keyword(s):  
Phytochemical Analysis ◽  
Bridelia Ferruginea

scholarly journals Development of mango (Mangifera indica L.) energy drinks

2017 ◽  
Vol 70 (1) ◽  
pp. 8115-8121
Author(s):  
Carlos Julio Márquez Cardozo ◽  
Carlos Andrés Jiménez Castañeda ◽  
Carolina Sofía Salazar Ripoll
Keyword(s):  
Confidence Level ◽  
Carboxymethyl Cellulose ◽  
High Density Polyethylene ◽  
Mangifera Indica ◽  
Storage Period ◽  
Soluble Solids ◽  
Browning Index ◽  
Physico Chemical ◽  
Off Flavors ◽  
The One

The effect of two hydrocolloids, pectin and carboxymethyl cellulose (CMC), was evaluated in mango beverage stability (Mangifera indica L.) formulated and developed with caffeine at a concentration of 30 mg/100 mL. The physico-chemical and sensory characteristics of color, acidity, viscosity, total soluble solids, pH, flavor, aroma and texture were studied every three days over a 12-day period. The beverages were packaged in high-density polyethylene containers with a 250 mL capacity and were stored at 5 °C and 90% RH for the duration of the experimentation period. The drinks with added pectin showed greater stability and lower acidity values than the control, but higher values than those prepared with CMC. The drinks made with CMC had a significantly higher viscosity at a 95% confidence level than those made with pectin or the control beverages. The treatment that showed the lowest browning index was the one added with pectin. Concerning the sensory evaluation, the drinks showed significant differences at a 95% confidence level; the drink made with pectin was the most widely accepted. It was concluded that the most stable drinks were those made with pectin because they presented the lowest height in millimeters of precipitate solids over the storage period. No off-flavors in beverages were perceived by the judges.

scholarly journals IDENTIFICATION OF CHEMICAL COMPOSITION OF Eugenia aromatica AND ITS BIO-EFFICACY AGAINST Sitophilus oryzae (L.) AND Tribolium castaneum (HERBST)

2019 ◽  
pp. 26-35
Keyword(s):  
Gas Chromatography ◽  
Chemical Composition ◽  
Essential Oil ◽  
Sitophilus Oryzae ◽  
Management Program ◽  
Phytochemical Analysis ◽  
Flower Buds ◽  
Plant Oil ◽  
Potential Source ◽  
F1 Progeny

In this investigation plant oil and powder of E. aromatica were evaluated under laboratory conditions to determine their toxicity, fumigant effect and impact on F1 progeny of S. oryzae and T. castaneum adults. Essential oil and powder of flower buds obtained from Eugenia aromatica were purified and analyzed by Gas-Chromatography–Mass Spectrometer (GC-MC). The results obtained showed that the two products of E. aromatica had good disorders on the all tested parameters. For toxicity and fumigant effect the oil was the premier compared to powder. In addition, that the two products completely prevented the F1 emergence of the two insects. In respect of the toxicity and fumigation the T. castaneum was more tolerant than S. oryzae adults. Phytochemical analysis showed that euegnol (89.62%) was the premier component of essential oil, while euegnol (78.66%), caryophyllene (6.30%), -a-Terpinyl acetate (1.35%) were the major components for its powder. These findings suggest application of E. aromatica products as suitable tools as a potential source of insecticides, alternative to synthetic insecticides or using these products in integrated pest management program against stored product insects, especially S. oryzae or T. castaneum adults.

scholarly journals Evaluation of in vitro antiplasmodial effect of extracts from seven medicinal plants used to treat malaria in Côte d'Ivoire.

Bioimpacts ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 151-157
Author(s):  
Jeanne Akissi Koffi ◽  
Kigbafori Dieudonné Silué ◽  
Dominique Konan Tano ◽  
Trésor Marius Dable ◽  
William Yavo
Keyword(s):  
Aqueous Extract ◽  
Mangifera Indica ◽  
Antiplasmodial Activity ◽  
Phytochemical Analysis ◽  
Moderate Activity ◽  
Methanolic Extracts ◽  
Fluorescence Reading ◽  
Cumulative Rate ◽  
Therapeutic Alternatives

Introduction: Plasmodium falciparum strains had been increasingly resistant to commonly used molecules including artemisinin. It is therefore urges to find new therapeutic alternatives. Methods: In this study, the antiplasmodial activity of 21 extracts obtained from seven plants of the Anthocleista djalonensis, Cochlospermum planchonii, Harungana madagascariensis, Hoslundia opposita, Mangifera indica, Margaritaria discoidea and Pericopsis laxiflora of the Ivorian pharmacopoeia was evaluated on the chloroquine sensitive (NF54) and multi-resistant (K1) reference strains and on clinical isolates as well. The technique used was the microtiter method based on fluorescence reading with SYBR Green. Results: The aqueous extract of the bark of H. madagascariensis and methanolic extracts of P. laxiflora showed the best antiplasmodial activity with IC50 values of 6.16 µg/mL and 7.44 µg/mL, respectively. On the other hand, extracts of M. indica showed a very moderate activity with IC50 values between 15 µg/mL and 50 µg/mL (5<IC50<50 µg/mL) on the same strains of P. falciparum. Only the aqueous extract of A. djalonensis had IC50 values greater than 50 µg/mL. The phytochemical analysis showed a strong presence of polyphenols and alkaloids in extracts with a cumulative rate of 90.47% and 95.23%, respectively. Conclusion: The results obtained were also justified by the composition of these plants, which have several secondary metabolites involved in the treatment of malaria. The antiplasmodial properties of these plants could partially justify their use in malaria treatment. Further studies on these extracts are needed to manufacture a stable galenic formulation for the development of an improved traditional medicine.

scholarly journals Humans, Animals, Food and Environment: One Health Approach against Global Antimicrobial Resistance

Antibiotics ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 346
Author(s):  
Marcello Iriti ◽  
Sara Vitalini ◽  
Elena Maria Varoni
Keyword(s):  
Public Health ◽  
Antimicrobial Resistance ◽  
One Health ◽  
Animal Health ◽  
Global Public Health ◽  
Antimicrobial Drugs ◽  
Potential Source ◽  
Antibiotic Drugs ◽  
Hospital Stays ◽  
The One

Antimicrobial resistance represents one of the most relevant threats to global public health and food security, affecting anyone, of any age, in any country and is responsible for longer hospital stays, higher medical costs and increased mortality. Resistant microorganisms are present in humans, animals, food and the environment, and, therefore, the One Health approach is very promising to counteract antimicrobial resistance, since human health and animal health are connected to each other and with the environment and the latter a potential source of resistant microorganisms. In this context, the need for novel antimicrobial drugs has stimulated the exploration of plant products as a source of novel phytotherapeutics able to reverse antimicrobial resistance when used in combination with conventional antibiotic drugs.

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