scholarly journals Activation of Biodefense System by Low-Dose Irradiation or Radon Inhalation and Its Applicable Possibility for Treatment of Diabetes and Hepatopathy

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Takahiro Kataoka ◽  
Kiyonori Yamaoka
Keyword(s):  
Liver Disease ◽  
Alloxan Diabetes ◽  
Low Dose ◽  
Oxygen Species ◽  
Sod Activity ◽  
Oxygen Stress ◽  
Dose Irradiation ◽  
Treatment Of Diabetes ◽  
Radon Inhalation ◽  
Nonalcoholic Liver Disease

Adequate oxygen stress induced by low-dose irradiation activates biodefense system, such as induction of the synthesis of superoxide dismutase (SOD) and glutathione peroxidase. We studied the possibility for alleviation of oxidative damage, such as diabetes and nonalcoholic liver disease. Results show that low-dose -irradiation increases SOD activity and protects against alloxan diabetes. Prior or post-low-dose X- or -irradiation increases antioxidative functions in livers and inhibits ferric nitrilotriacetate and carbon tetrachloride-induced (CCl4) hepatopathy. Moreover, radon inhalation also inhibits CCl4-induced hepatopathy. It is highly possible that low-dose irradiation including radon inhalation activates the biodefence systems and, therefore, contributes to preventing or reducing reactive oxygen species-related diabetes and nonalcoholic liver disease, which are thought to involve peroxidation.

scholarly journals Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation

2011 ◽  
Vol 146 (1-3) ◽  
pp. 360-363 ◽  
Author(s):  
T. Kataoka ◽  
A. Sakoda ◽  
M. Yoshimoto ◽  
S. Nakagawa ◽  
T. Toyota ◽  
...  
Keyword(s):  
Low Dose ◽  
Dose Irradiation ◽  
Radon Inhalation ◽  
Lifestyle Diseases

Inhibition of Neointimal Proliferation With Low-Dose Irradiation From a β-Particle–Emitting Stent

Circulation ◽  
1996 ◽  
Vol 93 (3) ◽  
pp. 529-536 ◽  
Author(s):  
John R. Laird ◽  
Andrew J. Carter ◽  
William M. Kufs ◽  
Timothy G. Hoopes ◽  
Andrew Farb ◽  
...  
Keyword(s):  
Low Dose ◽  
Dose Irradiation ◽  
Neointimal Proliferation

scholarly journals Low-dose irradiation reduces forced swim test-induced immobility and oxidative stress in mice

2021 ◽  
Vol 165 ◽  
pp. 56-57
Author(s):  
Shota Naoe ◽  
Takahiro Kataoka ◽  
Hina Shuto ◽  
Junki Yano ◽  
Tetsuya Nakada ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Low Dose ◽  
Forced Swim Test ◽  
Swim Test ◽  
Dose Irradiation ◽  
Forced Swim ◽  
And Oxidative Stress

scholarly journals Editorial “Nutrition and Dietary Intake for Liver-Related Diseases”

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 390
Author(s):  
Ewa Stachowska ◽  
Karolina Jakubczyk ◽  
Dominika Maciejewska-Markiewicz
Keyword(s):  
Liver Disease ◽  
Dietary Intake ◽  
Special Issue ◽  
Nonalcoholic Liver Disease

In this special issue, we focus on the role of nutrition in the therapy of nonalcoholic liver disease (NAFLD) [...]

Combined treatments of low dose irradiation with antimicrobials for inactivation of foodborne pathogens on fresh pork

Food Control ◽  
2021 ◽  
Vol 125 ◽  
pp. 107977
Author(s):  
Ziyi Hu ◽  
Yingping Xiao ◽  
Bingkui Wang ◽  
Tony Z. Jin ◽  
Wentao Lyu ◽  
...  
Keyword(s):  
Foodborne Pathogens ◽  
Low Dose ◽  
Combined Treatments ◽  
Dose Irradiation

Primary Explants of Human Uroepithelium Show an Unusual Response to Low-Dose Irradiation with Cobalt-60 Gamma Rays

1995 ◽  
Vol 142 (2) ◽  
pp. 181 ◽  
Author(s):  
C. Mothersill ◽  
J. Harney ◽  
F. Lyng ◽  
D. Cottell ◽  
K. Parsons ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Dose Irradiation ◽  
Primary Explants

scholarly journals Low-dose irradiation promotes Rad51 expression by down-regulating miR-193b-3p in hepatocytes

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Eon-Seok Lee ◽  
Yeo Jin Won ◽  
Byoung-Chul Kim ◽  
Daeui Park ◽  
Jin-Han Bae ◽  
...  
Keyword(s):  
Low Dose ◽  
Dose Irradiation

scholarly journals Cromoglycate and nedocromil enhanced the reactive oxygen species-dependent suppressions with, but not without, dexamethasone in ischaemic and histamine paw oedema of mice

1997 ◽  
Vol 6 (5-6) ◽  
pp. 369-374
Author(s):  
Y. Oyanagui
Keyword(s):  
Reactive Oxygen Species ◽  
Hydrogen Peroxide ◽  
Superoxide Dismutase ◽  
Glucocorticoid Receptor ◽  
Low Dose ◽  
Natural Antioxidant ◽  
Target Cells ◽  
Oxygen Species ◽  
Paw Oedema ◽  
Β Carotene

Anti-inflammatory actions of two anti-allergic drugs, alone or with dexamethasone (Dex) were examined in two models, because inflammation is claimed to be important for allergic events, especially for asthma. Cromoglycate and nedocromil were tested in ischaemic- and histamineinduced paw oedema models of mice. These antiallergic drugs (1–100 mg/kg, i.p.) failed to suppress these oedemata, but enhanced the suppressions by a low dose of dexamethasone (0.1 mg/kg, s.c.) at 3–8 h after Dex injection. The mode of effects by anti-allergic drugs resembled that of a natural antioxidant (α-tocopherol, β-carotene etc.), and was different from that of an immunosuppressant like FK506. The enhancing potencies of the two anti-allergic drugs were similar at 6 h after Dex in both oedemata, and were diminished by superoxide dismutase (SOD) or catalase (i.p.). Cycloheximide completely abolished suppressions. Nedocromil, but not cromoglycate, inhibits inflammatory events. Therefore, there are common unknown actions by which the two anti-allergics enhance suppression by Dex. A possible mechanism of this action was supposed to enhance the superoxide and/or hydrogen peroxide-dependent glucocorticoid receptor (GR) signalling in the target cells.

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