scholarly journals Effects of functional foods in diabetic patients: a systematic review

2021 ◽  
Vol 14 (3) ◽  
Author(s):  
Delma Conceição Pereira das Neves ◽  
Durval Ribas Filho
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Diabetes Mellitus Type 2 ◽  
Functional Foods ◽  
Randomized Clinical Trials ◽  
Diabetes Mellitus Type ◽  
Diabetic Patients ◽  
Adequate Diet ◽  
Insulin Control

The control of Type II Diabetes Mellitus is directly related to the dietary profile, so an adequate diet for this group of patients must be implemented as soon as possible. But what foods can we use to facilitate glycemic and insulin control? Therefore, this study aims to systematically review the literature on the effects of functional foods in diabetic patients. Method: Systematic review of randomized clinical trials published between 2014 and 2021. Using as descriptors: Diabetes Mellitus Type 2 (Diabetes Mellitus Type 2), Functional Food. Results: Of the 566 articles found, 65 articles were selected, which passed the PEDro scale of methodological quality, and 11 articles were included. Of which they addressed different functional foods and their effects on different variables in diabetic patients. It can be concluded that several foods have beneficial effects on glycemic and insulin control in diabetic patients. Still, as a benefit, they had side effects in controlling dyslipidemia, blood pressure, and BMI.

Evaluation of the alterations in the serum blood sugar level, the activity of AST and ALT enzymes of diabetes mellitus type 2 in Iraqi women patients

2021 ◽  
Vol 16 (8) ◽  
pp. 98-102
Author(s):  
Hashim Abdul Razzaq Iman ◽  
Hussein Murtadha Jinan
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Diabetes Mellitus Type 2 ◽  
Correlation Factor ◽  
Diabetes Mellitus Type ◽  
Fasting Blood Sugar ◽  
Diabetic Patients ◽  
Cell Dysfunction ◽  
Iraqi Women

Diabetes mellitus type 2 (T2DM) results from beta cell dysfunction or reduced action of insulin responsive. The objective of this study was to examine the relevance between blood sugar, the activity of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in fasting women diabetic patients in different durations. A total of sixty-eight women were divided into three groups: first a healthy group – non-diabetic (twenty-six women), second and third groups (twenty-one) were diabetic patients of age 35 – 50 and 51 – 69 years respectively. Serum fasting blood sugar was significantly (P < 0.05) elevated to 181.60 mg/dl in female patients with 35 – 50 years. The same effect happened in activity of AST to 32.91 u/L in 51 – 69 years and ALT was 28.43 u/L in 35 – 50 years. No significant differences were found between the aged and fasting blood sugar, AST and ALT in diabetic patients. The correlation factor (r) between fasting blood sugar and the activity of ALT was highly significant.

ARTIFICIAL NEURAL NETWORKS FOR ESTIMATING GLOMERULAR FILTRATION RATE BY URINARY DIPSTICK FOR TYPE 2 DIABETIC PATIENTS

2016 ◽  
Vol 28 (03) ◽  
pp. 1650016
Author(s):  
Yu Chu-Su ◽  
Chien-Sheng Liu ◽  
Ruey-Shin Chen ◽  
Chii-Wann Lin
Keyword(s):  
Diabetes Mellitus ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Diabetes Mellitus Type 2 ◽  
Filtration Rate ◽  
Optimal Combination ◽  
Diabetes Mellitus Type ◽  
Diabetic Patients ◽  
Test Items

Background: The result of a standard urinary dipstick from a patient with diabetes mellitus type 2 can be used to predict the estimated glomerular filtration rate (eGFR). We designed a multilayer perceptron (MLP) to investigate the possibility and optimal number of variables for the prediction. Methods: A total of 299 volunteers with diabetes mellitus type 2 were included. The blood and urine samples from volunteers were analyzed for blood sugar, glycated hemoglobin, serum creatinine, and urine chemistry. The urine chemistry was examined by a standard urinary dipstick. Volunteer age and gender and six test items of the dipstick were set as eight variables for this study. The eight variables were grouped and examined for the optimal combination. The eight variables from 232 of 299 volunteers were used to train an MLP for the optimal variables. The performance of trained MLP was validated by the data from 69 of 232 volunteers. Results: The optimal combination for variables was the six test items of the dipstick and volunteer age. The area under the curve (0.928), accuracy (0.879), sensitivity (0.83), and specificity (0.88) of the trained MLP were examined. Conclusions: The results demonstrate the eGFR prediction potential of the results of a urinary dipstick using this method.

scholarly journals Systematic Review: Are the Elderly With Diabetes Mellitus Type 2 Prone to Fragility Fractures?

Cureus ◽  
2021 ◽  
Author(s):  
Ioannis Papaioannou ◽  
Georgia Pantazidou ◽  
Zinon Kokkalis ◽  
Neoklis Georgopoulos ◽  
Eleni Jelastopulu
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Diabetes Mellitus Type 2 ◽  
Fragility Fractures ◽  
The Elderly ◽  
Diabetes Mellitus Type

An Evaluation of Hemoglobin Concentration in Patients with Diabetes Mellitus Type 2

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Karem Kdaer Karem ◽  
Saba Ibrahim Salih ◽  
Wafaa Kadhim Jassim
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 2 ◽  
Hemoglobin Concentration ◽  
The Body ◽  
Diabetes Mellitus Type ◽  
Diabetic Patients ◽  
Other Information ◽  
Patients With Diabetes ◽  
Age Range

The second type of diabetes Mellitus is the most common type of diabetes, its represent about 90-95% of diabetes cases. In this disease, the response of the body to insulin does not occur properly in a condition known as insulin resistance. The diabetes may accompany with anemia because the hormone erythropoietin (EPO) which is produced by the kidneys is regulates red blood cell production and the Kidney has been damaged at several levels as a complication of diabetes, the complication range from diabetic nephropathy to chronic kidney disease. This study was conducted at the AL-Kafeel Hospital, Kerbala from October 2016 to December2016. The study included 60 adult patients with age range from 43-67 years and having diabetes mellitus type 2. Fasting blood sugar and Hb tests were made and accompanied with other information like age and duration of diabetes mellitus. The results show that 43% of diabetic patients had anemia and there is a strong negative connection between Hb levels and the duration of getting diabetes (p0.01). We conclude from this study that anemia is may developed in Type 2DM patients and the diabetic patients should be taken care of toprevent the development of diseases and other complications.

scholarly journals Dipeptidyl peptidase 4 inhibitors in modern domestic practice

2020 ◽  
pp. 14-18
Author(s):  
A. S. Ametov ◽  
N. A. Chernikov ◽  
O. A. Knyshenko
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 2 ◽  
Randomized Clinical Trials ◽  
Combined Treatment ◽  
Dipeptidyl Peptidase ◽  
Low Risk ◽  
Diabetes Mellitus Type ◽  
Dipeptidyl Peptidase 4 ◽  
Dipeptidyl Peptidase 4 Inhibitors

The choice of treatment of diabetes mellitus type 2 is personalized, based on modern Russian and international algorithms for management of such patients. Given the initial level of decompensation of the disease at the time of diagnosis (at the level of glycated hemoglobin), most patients with type 2 diabetes at the time of initiation of therapy requires the combined treatment, at least two antidiabetic drugs. In modern conditions, on the basis of evidence-based medicine, priority should be given to drugs with a low risk of hypoglycemic conditions and do not affect or reduce body weight. In this article we consider a class of inhibitors of dipeptidyl peptidase 4, which entered into clinical practice since 2006 for the treatment of patients suffering from diabetes mellitus type 2, with an emphasis on drugs used in the Russian Federation. Today in our country there are seven members of the class of inhibitors of dipeptidyl peptidase 4. The results of the major randomized clinical trials (SAVOR-TIMI 53, EXAMINE, TECOS, CAROLINA), which studied the cardiovascular safety of dipeptidyl peptidase 4 inhibitors, showed the intra class heterogeneity with respect to data on the frequency of hospitalizations due to chronic heart failure. Have proven cardiovascular neutrality in relation to the primary combined cardiovascular outcome was MACE, including cardiovascular death, nonfatal myocardial infarction and nonfatal stroke. A major problem is the choice of effective glucose-lowering therapy to special patient groups. Assign their profession the safety of drugs plays a key role. With its high efficiency and unique glucosidation mechanism of action, guaranteeing a low risk of hypoglycemia and high safety, the drugs of this group has firmly taken its niche among the priority hypoglycemic drugs.

scholarly journals Efficacy of Diabetes Education in Adults With Diabetes Mellitus Type 2 in Primary Care: A Systematic Review

2020 ◽  
Vol 52 (2) ◽  
pp. 155-163
Author(s):  
Celia Cruz‐Cobo ◽  
M José Santi‐Cano
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Primary Care ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Education ◽  
Diabetes Mellitus Type

scholarly journals Effect of hyperbaric oxygen treatment on oxidative stress in patients having diabetes mellitus type 2

2009 ◽  
Vol 62 (5-6) ◽  
pp. 225-230 ◽  
Author(s):  
Sandra Tepic ◽  
Miodrag Zivkovic ◽  
Negra Terzic ◽  
Radmila Krivokuca ◽  
Biljana Ljesevic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
High Pressure ◽  
Diabetes Mellitus Type 2 ◽  
Vascular Complications ◽  
Vascular Complication ◽  
Diabetes Mellitus Type ◽  
Diabetic Patients ◽  
Peripheral Vascular ◽  
Group I

Introduction The aim of our study was to investigate the influence of breathing oxygen under high pressure on potential prooxidative activity in diabetic patients with serious vascular complications. Material and methods 24 patients with diabetes mellitus type 2, were divided into two groups, 12 patients each, by degree of peripheral vascular complications (by Wagner's scale). The group I was composed of 4 women and 8 men, their average age being 70 years, and average Diabetes duration of 12 years, without clinically manifest peripheral vascular complication (Wagner 0). The group II was composed of 4 women and 8 men, their average age being 74 years, and average illness duration of 17 years, having peripheral vascular complications, classified by Wagner's scale 1-5. Blood samples for biochemical analysis were taken before the therapy, then on the 3rd, 5th, 7th and 10th day of hyperbaric oxygenation treatment. The values of superoxide anion radical (O-), hydrogen peroxide (H2O2) and TBARS as a parameter of lipid peroxidation were measured during the HBOt. All examined patients were treated with the same therapy protocol (10 HBO treatments, under pressure of 1.7-2.2 bar, in duration of 60 minutes). The therapy was provided in monoplace oxygen hyperbaric chamber. Results The obtained results show no statistically significant increase in the values of O2-, H2O2, TBARS during the HBOt compared to the values before the HBOt. However, O2-, H2O2 were significantly reduced after HBOt. Conclusion On the basis of these data, we can conclude that the use of oxygen under high pressure has no influence on the increased prooxidative activities in diabetic patients during and after HBOt, disregarding the degree of the present vascular damages.

scholarly journals Therapeutic Effect of Folate and Cobalamin in Diabetics

2021 ◽  
Author(s):  
Farah Qudsia ◽  
Samreen Riaz
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 2 ◽  
Microvascular Complications ◽  
Well Being ◽  
Diabetes Mellitus Type ◽  
Diabetic Patients ◽  
Cardiovascular Comorbidities ◽  
Enhance Insulin Sensitivity ◽  
High Chance

Diabetes Mellitus type 2 is a metabolic ailment. It is a condition when insulin is produced by our body but, it is not used properly by us. The number of diabetic patients is increasing in the whole world. The problem of obesity is also very closely related to it, which itself is expanding. The individuals diagnosed with type 2 Diabetes Mellitus have high chance of microvascular problems (like nephropathy, retinopathy and neuropathy). They are also at the verge of facing macrovascular ailments (like cardiovascular comorbidities). This indicates that many antidiabetic agents should be administered in combination, to maintain normal sugar level in blood. The management for the patients suffering from diabetes should be effective and harmless for them. It should also improve the general well-being of the patients. So many remedies have been developed for the management of diabetes. Several of them are being developed. We should enhance insulin sensitivity to let our body use insulin effectively. We also must stop the increasing pancreatic β-cell failure which is a specific characteristic of Diabetes Mellitus type 2. The microvascular complications must also be avoided or revoked. Our direst need is to develop agents which may help us in achieving goals mentioned earlier. Many micronutrients are involved in combating the Diabetes Mellitus and complication associated to the malady. These micronutrients are vitamins. Our main focus in this chapter are Vitamins B9 (Folate) and B12 (Cobalamin). Many researches have shown that the said parameters were decreased in patients suffering from Diabetes Mellitus. The level of these two vitamins should be maintained to the normal level and not toward the border line. The maintained level of these vitamins will help in controlling the main problems in patients suffering from Diabetes Mellitus like neuropathy, anemia and many others. By taking these vitamins along with other preventive measures, Diabetes Mellitus can be controlled and can be less dangerous.

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